KEGG   ENZYME: 3.2.1.205Help
Entry
EC 3.2.1.205                Enzyme                                 

Name
isomaltose glucohydrolase
Class
Hydrolases;
Glycosylases;
Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
BRITE hierarchy
Sysname
isomaltose 6-alpha-glucohydrolase (configuration-inverting)
Reaction(IUBMB)
isomaltose + H2O = beta-D-glucose + D-glucose [RN:R11791]
Reaction(KEGG)
Substrate
isomaltose [CPD:C00252];
H2O [CPD:C00001]
Product
beta-D-glucose [CPD:C00221];
D-glucose [CPD:C00031]
Comment
The enzyme catalyses the hydrolysis of alpha-1,6-glucosidic linkages from the non-reducing end of its substrate. Unlike EC 3.2.1.10, oligo-1,6-glucosidase, the enzyme inverts the anomeric configuration of the released residue. The enzyme can also act on panose and maltotriose at a lower rate.
History
EC 3.2.1.205 created 2017
Orthology
K22308  isomaltose glucohydrolase
Genes
NCA: Noca_4631
KFL: Kfla_1896
NOA: BKM31_21910
AYM: YM304_31650
Taxonomy
Reference
1  [PMID:27302067]
  Authors
Tagami T, Miyano E, Sadahiro J, Okuyama M, Iwasaki T, Kimura A
  Title
Two Novel Glycoside Hydrolases Responsible for the Catabolism of Cyclobis-(1-->6)-alpha-nigerosyl.
  Journal
J Biol Chem 291:16438-47 (2016)
DOI:10.1074/jbc.M116.727305
  Sequence
[kfl:Kfla_1896]
Other DBs
ExplorEnz - The Enzyme Database: 3.2.1.205
IUBMB Enzyme Nomenclature: 3.2.1.205
ExPASy - ENZYME nomenclature database: 3.2.1.205
BRENDA, the Enzyme Database: 3.2.1.205

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