KEGG ENZYME: 4.2.3.60

ENZYME: 4.2.3.60

Entry

EC 4.2.3.60 Enzyme

Name

germacrene C synthase

Class

Lyases;
Carbon-oxygen lyases;
Acting on phosphates

Sysname

(2E,6E)-farnesyl-diphosphate diphosphate-lyase (germacrene-C-forming)

Reaction(IUBMB)

(2E,6E)-farnesyl diphosphate = germacrene C + diphosphate [RN:R09624]

Reaction(KEGG)

R09624

Substrate

(2E,6E)-farnesyl diphosphate [CPD:C00448]

Product

germacrene C [CPD:C19747];
diphosphate [CPD:C00013]

History

EC 4.2.3.60 created 2011

Pathway

ec00909

Sesquiterpenoid and triterpenoid biosynthesis

Orthology

K15802

germacrene C synthase

Genes

SLY:	543549(SSTLE1)

Reference

1 [PMID:9482865]

Authors

Colby SM, Crock J, Dowdle-Rizzo B, Lemaux PG, Croteau R

Title

Germacrene C synthase from Lycopersicon esculentum cv. VFNT cherry tomato: cDNA isolation, characterization, and bacterial expression of the multiple product sesquiterpene cyclase.

Journal

Proc Natl Acad Sci U S A 95:2216-21 (1998)
DOI:10.1073/pnas.95.5.2216

Sequence

[sly:543549]

Other DBs

ExplorEnz - The Enzyme Database:

4.2.3.60

IUBMB Enzyme Nomenclature:

4.2.3.60

ExPASy - ENZYME nomenclature database:

4.2.3.60

BRENDA, the Enzyme Database:

4.2.3.60

DBGET integrated database retrieval system