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6-tuliposide B D-glucose-lyase (tulipalin B-forming)

6-tuliposide B = tulipalin B + D-glucose [RN:R11215]

R11215
Reaction

6-tuliposide B [CPD:C21186]

The enzyme, characterized from pollen of the plant Tulipa gesneriana (tulip), catalyses the intramolecular transesterification of 6-tuliposide B to form the antibiotic aglycon tulipalin B as a sole product. It does not catalyse the hydrolysis of 6-tuliposide B to form a hydroxy acid. The enzyme has marginal activity with 6-tuliposide A. cf. EC 4.2.99.22, tuliposide A-converting enzyme.

EC 4.2.99.23 created 2016

1  [PMID:25997073]

Nomura T, Murase T, Ogita S, Kato Y

Molecular identification of tuliposide B-converting enzyme: a lactone-forming carboxylesterase from the pollen of tulip.

Plant J 83:252-62 (2015)
DOI:10.1111/tpj.12883

[ag:BAR97239]