KEGG ENZYME: 5.3.1.27

ENZYME: 5.3.1.27

Entry

EC 5.3.1.27                 Enzyme

Name

6-phospho-3-hexuloisomerase;
3-hexulose-6-phosphate isomerase;
phospho-3-hexuloisomerase;
PHI;
6-phospho-3-hexulose isomerase;
YckF

Class

Isomerases;
Intramolecular oxidoreductases;
Interconverting aldoses and ketoses, and related compounds

Sysname

D-arabino-hex-3-ulose-6-phosphate isomerase

Reaction(IUBMB)

D-arabino-hex-3-ulose 6-phosphate = D-fructose 6-phosphate [RN:R05339]

Reaction(KEGG)

R05339 > R09780

Substrate

D-arabino-hex-3-ulose 6-phosphate [CPD:C06019]

Product

D-fructose 6-phosphate [CPD:C00085]

Comment

This enzyme, along with EC 4.1.2.43, 3-hexulose-6-phosphate synthase, plays a key role in the ribulose-monophosphate cycle of formaldehyde fixation, which is present in many microorganisms that are capable of utilizing C1-compounds [1]. The hyperthermophilic and anaerobic archaeon Pyrococcus horikoshii OT3 constitutively produces a bifunctional enzyme that sequentially catalyses the reactions of EC 4.1.2.43 (3-hexulose-6-phosphate synthase) and this enzyme [4].

History

EC 5.3.1.27 created 2008

Pathway

ec00030

Pentose phosphate pathway

ec00680

Methane metabolism

ec01100

Metabolic pathways

ec01120

Microbial metabolism in diverse environments

Orthology

K08094

6-phospho-3-hexuloisomerase

K13831

3-hexulose-6-phosphate synthase / 6-phospho-3-hexuloisomerase

Genes

ECG:	E2348C_4131

ECP:

ECP_4027

ENA:	ECNA114_4122

ECOS:

EC958_4293

ECV:	APECO1_2643

ECQ:	ECED1_4515

EUM:	ECUMN_2964

ECI:	UTI89_C4398

EIH:	ECOK1_4282(hxlB)

ECZ:	ECS88_4262

ECC:

c4757

ELN:	NRG857_10055 NRG857_19035

ESE:

ECSF_3670

ECL:	EcolC_1650

EAB:	ECABU_c43160

ELU:	UM146_19310

ELC:

i14_4352

ELD:

i02_4352

ELF:	LF82_319 LF82_584

ECOI:

ECOPMV1_04171(hxlB)

ECOJ:

P423_21200

STM:

STM2756

SEO:	STM14_3321

SEV:	STMMW_27241

SEY:	SL1344_2740(hxlB)

SEM:	STMDT12_C28080

SEJ:	STMUK_2744

SEB:	STM474_2891(hxlB)

SEF:	UMN798_2990(hxlB)

SETU:

STU288_13945

SETC:

CFSAN001921_03335

SENR:

STMDT2_26621

SEND:

DT104_27581

SENI:

CY43_14400

SEH:	SeHA_C2930(hxlB) SeHA_C3252

SHB:	SU5_03244 SU5_03524

SENH:

CFSAN002069_17050 CFSAN002069_18500

SEEH:

SEEH1578_01225 SEEH1578_22580

SEA:	SeAg_B4594

SENS:

Q786_21245

SALZ:

EOS98_20670

ECLZ:

LI64_16170

EEC:	EcWSU1_A067(hxlB) EcWSU1_A079(hxlB)

ECAN:

CWI88_05390(hxlB)

ECHG:

FY206_18840(hxlB)

EHU:	D5067_0012780 D5067_0012835

KPN:

KPN_02958

KPY:	KPNIH31_18205

KOY:	J415_13235

KOC:	AB185_13835

KLW:	DA718_10175(hxlB)

RTG:	NCTC13098_03928(hxlB)

CITZ:

E4Z61_22605(hxlB)

CEM:	LH23_07975

CLAP:

NCTC11466_04027(hxlB)

PGE:	LG71_08970

ESC:	Entcl_3467

KLE:	AO703_04670

KOR:	AWR26_05120

KRD:	A3780_18895

PSGC:

G163CM_13990(hxlB_1) G163CM_25830(hxlB_2)

SUPE:

P0H77_01460

EBF:	D782_2346 D782_3531

PSTS:

E05_34000

YAS:	N0H69_06815

SRY:	M621_16140

SOF:	NCTC11214_04390(rpiR_3)

RAQ:	Rahaq2_1981

EAME:

GXP68_02485

SOD:	Sant_0060 Sant_0809

SLIG:

GTU79_11105

EPE:	CI789_05880 CI789_22800

ERP:	LJN55_13995

EGE:	EM595_p1057

VSH:	BSZ05_17120

MCA:	MCA2738 MCA3044 MCA3050

METU:

GNH96_02040(hxlB) GNH96_02070(hxlB) GNH96_04130(hxlA)

MMT:	Metme_4079

MDN:	JT25_012680

MDH:	AYM39_02475

MKO:	MKLM6_0537

MPAD:

KEF85_12790(hxlB)

MRP:	NM686_001840(hxlB)

MAH:	MEALZ_1912(hpsi2) MEALZ_3952(hpi1)

MBUR:

EQU24_11340(hxlA)

MPSY:

CEK71_00430(hxlB) CEK71_18985

MMAI:

sS8_1134 sS8_1148

MMOB:

F6R98_00320(hxlB)

MEIN:

methR_P2884

MOZ:	MoryE10_06560 MoryE10_07580

MISZ:

MishRS11D_06520

MESL:

KKZ03_07030(hxlB)

MEJ:	Q7A_2502(hxlB)

MEC:

Q7C_1683

MPIN:

LGT42_003275(hxlB)

HSR:	HSBAA_22450

AMED:

B224_3863

GAP:	GAPWK_2238

ORB:	IPMB12_02090 IPMB12_08425(hxlB)

PGP:	CUJ91_31790

PMEG:

FNZ07_17940

BPDZ:

BBN53_16310

ACID:

CBP33_16730

CSER:

CCO03_04105

MFA:

Mfla_1653

MMB:

Mmol_1337

MEH:

M301_1546

MEI:	Msip34_1497

MEP:

MPQ_1560

MBAC:

BN1209_0772(rmpB)

MBAT:

BN1208_0844(hpi)

MEU:	ACJ67_07425

MPAU:

ZMTM_11890

MLO:

mlr8483

MLN:	A9174_25070

MCI:	Mesci_4415

MCIC:

A4R28_04980

MOP:	Mesop_4866

MAM:	Mesau_04475

MAMO:

A6B35_17480

MESW:

A9K65_024400

MHUA:

MCHK_1793

MJR:	EB229_25310

MERD:

EB233_21705

RLS:	HB780_00785

XDI:	EZH22_21185

LNE:	FZC33_21730

APRA:

G3A50_17170

APOL:

K9D25_19750

CHEL:

AL346_04430

CDQ:	BOQ54_15260

PLEO:

OHA_1_04238(hxlB)

MEY:	TM49_19260

AUA:	M673_09235

AALA:

IGS74_06075

AALM:

LUX29_06865

JIE:	OH818_14325

NOH:	G5V57_00565

ACUT:

MRB58_00780

RUT:	FIU92_21995(hxlB)

RPON:

G3256_02485

DSH:

Dshi_0552

SDO:	SD1155_05645(hxlB)

PSEW:

JHW44_14960

PTP:	RCA23_c24710

GEH:	HYN69_12175

TAW:	EI545_16820

BOO:	E2K80_03625

GAL:	A0U94_14270

GSP:	IGS75_14270

KBA:	A0U89_15350

LCK:	HN018_09235

SKT:	IGS68_31905

SMUC:

JL100_034505

SROE:

JL101_029165

RRU:

Rru_A1367

RRF:

F11_07060

NSA:	Nitsa_1661

SLH:	YH65_04860

DAO:	Desac_1176 Desac_1177

AORY:

AMOR_02900

BSU:	BSU03450(hxlB)

BSR:	I33_0396(hxlB)

BSL:

A7A1_1852

BSH:	BSU6051_03450(hxlB)

BSY:	I653_01725

BSUT:

BSUB_00395(hxlB)

BSUL:

BSUA_00395(hxlB)

BSUS:

Q433_02065

BSO:	BSNT_06680(hxlB)

BSN:	BSn5_13310

BSQ:	B657_03450(hxlB)

BSX:	C663_0336(hxlB1) C663_0337(hxlB2)

BSP:	U712_01785

BSS:	BSUW23_01785(hxlB)

BST:	GYO_0558(hxlB)

BLI:	BL02046(hxlB)

BLD:	BLi02804(hxlB)

BLH:	BaLi_c28990(hxlB)

BAY:	RBAM_003620(hxlB)

BAQ:	BACAU_0302(hxlB)

BYA:	BANAU_0304(hxlB)

BAMP:

B938_01570

BQY:	MUS_0324(hxlB)

BAML:

BAM5036_0321(hxlB)

BAMA:

RBAU_0336(hxlB)

BAMN:

BASU_0320(hxlB)

BAMB:

BAPNAU_0306(hxlB)

BAMT:

AJ82_01975

BAMY:

V529_03240(hxlB)

BMP:	NG74_00344(hxlB)

BAO:	BAMF_0309(hxlB)

BAZ:	BAMTA208_01550(hxlB)

BQL:	LL3_00317(hxlB)

BXH:	BAXH7_00320(hxlB)

BAMI:

KSO_017860

BAMC:

U471_03220

BAMF:

U722_01855

BSIA:

CWD84_20195(hxlB)

BAE:	BATR1942_20405

BVM:	B9C48_01840

BSON:

S101395_01723(hxlB)

BHT:	DIC78_08245(hxlB)

BMOJ:

HC660_03850(hxlB)

BTEQ:

G4P54_01940(hxlB)

BIQ:	AN935_01790

BPU:

BPUM_2332

BPUM:

BW16_12645

BPUS:

UP12_11775

BIF:	N288_21400 N288_22475

BMET:

BMMGA3_06840(phi)

BSM:	BSM4216_0640

BGY:	BGLY_3089(hxlB)

BXI:	BK049_15325

BALT:

CFN77_12445(hxlB)

BAER:

BAE_00120(hxlB)

BSAF:

BSL056_12830

BIT:	BIS30_12295

BFD:	NCTC4823_01218(hxlB_1) NCTC4823_03792(hxlB_2)

BSHI:

LGQ02_03490(hxlB)

BCAB:

EFK13_02145(hxlB)

BRY:	M0696_01995(hxlB)

BJS:

MY9_0360

GST:	HW35_08365

BACW:

QR42_11735

BACP:

SB24_07995

BACB:

OY17_04475

BACY:

QF06_00685

BACL:

BS34A_04020(hxlB)

BALM:

BsLM_0361

BACS:

AUL54_09015

BACQ:

DOE78_03630(hxlB)

BACA:

FAY30_22680 FAY30_22720(hxlB) FAY30_23230(hxlB)

BHAI:

KJK41_04670(hxlB)

BHK:	B4U37_02005

BCIR:

C2I06_12980(hxlB) C2I06_17425(hxlB)

BMQ:	BMQ_0890 BMQ_2941

BMD:	BMD_0890 BMD_2970

BMH:	BMWSH_4351(hxlB)

BMEG:

BG04_3185(hxlB) BG04_5471(hxlB) BG04_5931(hxlB)

BEO:	BEH_06015 BEH_12935

BFX:	BC359_14515

PKS:	IE339_01980(hxlB)

BCK:	BCO26_0268 BCO26_0583

BAG:	Bcoa_0594 Bcoa_0967

BCOA:

BF29_2768(hxlB) BF29_3094

BCL:	ABC3354(hxlB)

BKW:	BkAM31D_07115(hxlB_1) BkAM31D_16320(hxlB_2)

BGI:	BGM20_16790

BON:	A361_15690 A361_26105

CGOT:

J1899_06830(hxlB) J1899_20245 J1899_20285(hxlB) J1899_21660(hxlB)

CFIR:

NAF01_02055(hxlB) NAF01_14220(hxlB)

OIH:	OB2704 OB2807

OCN:	CUC15_15175(hxlB)

OJD:	NP439_19920(hxlB)

OON:	NP440_00985(hxlB) NP440_16415(hxlB) NP440_18620(hxlB)

GTK:	GT3570_09825

GLI:	GLN3_03385

GTN:

GTNG_1491

GMC:	GY4MC1_3094

GGH:	GHH_c21390(hxlB)

GJF:	M493_16825

GEA:	GARCT_00703(hxlB_1) GARCT_02003(hxlB_2)

GEL:	IB49_01650 IB49_02235

GSR:	GS3922_12385

GEJ:	A0V43_08220

GZA:	IC807_06465(hxlB)

GTH:	Geoth_3110

PTL:	AOT13_07075

PTB:	DER53_08125(hxlB)

PARG:

PspKH34_30150(hxlB)

ANM:	GFC28_663(hxlB)

ANL:	GFC29_963(hxlB)

AND:	GRQ40_09540(hxlB)

ACAI:

ISX45_01325(hxlB) ISX45_06730(hxlB)

HMN:	HM131_01670 HM131_14420

HLI:	HLI_12625(hxlB) HLI_12665(hxlB)

HNZ:	P9989_20135(hxlB)

VIG:	BKP57_09255

VIL:	CFK37_17675(hxlB)

VNE:	CFK40_05145(hxlB)

VPN:	A21D_01729(hxlB)

VPT:	KBP50_20760(hxlB)

VNT:	OLD84_16670(hxlB)

VIK:	KFZ58_14385(hxlB)

LEX:	Len3610_12145(hxlB)

FAR:	ABE41_010270 ABE41_017265

SJE:	AAV35_011125

APAK:

AP3564_06150

BMUR:

ABE28_013510 ABE28_019900

PBUT:

DTO10_07695(hxlB)

PPSR:

I6J18_08145(hxlB)

PFRI:

L8956_21560(hxlB)

GRC:	GI584_10020(hxlB)

SALE:

EPH95_16415(hxlB)

POF:	GS400_02165

NMK:	CHR53_10815(hxlB)

NTM:	BTDUT50_14175(hxlB)

NDT:	L1999_03000(hxlB) L1999_22995(hxlB)

MEKU:

HUW50_04035(hxlB) HUW50_04045 HUW50_16940(hxlB)

MSEM:

GMB29_08445(hxlB)

MDG:	K8L98_13985(hxlB) K8L98_15445(hxlB)

MLIT:

KDJ21_025575(hxlB) KDJ21_026160(hxlB)

AIA:	AWH56_012130(hxlB)

BLEN:

NCTC4824_00835(hxlB_1) NCTC4824_02163(hxlB_2)

SEDD:

ERJ70_14575(hxlB) ERJ70_18450(hxlB)

BVQ:	FHE72_04715(hxlB) FHE72_17340(hxlB)

RMF:	D5E69_06115(hxlB)

BBEV:

BBEV_0242(rmpB) BBEV_2196(hxlB)

PSUA:

FLK61_38800

STEA:

C0679_04050(hxlB)

PUK:	PU629_11125(hxlB) PU629_11400(hxlB)

SA0529

SAV:

SAV0571

SAW:

SAHV_0569

SAH:	SaurJH1_0608 SaurJH1_2813

SAJ:	SaurJH9_0594 SaurJH9_2737

SAM:

MW0526

SAS:

SAS0529

SAR:

SAR0575

SAC:

SACOL0618

SAX:	USA300HOU_0565

SAA:	SAUSA300_0556

SAO:	SAOUHSC_00554

SAE:

NWMN_0534

SAD:

SAAV_0534

SUU:	M013TW_0559(hxlB)

SUV:	SAVC_02445

SUE:

SAOV_0606

SUJ:	SAA6159_00525(hxlB)

SUK:	SAA6008_00579

SUC:	ECTR2_525(hxlB)

SUT:	SAT0131_00632

SUQ:	HMPREF0772_12617(hxlB)

SUZ:	MS7_0561(hxlB)

SUD:	ST398NM01_0646

SUX:	SAEMRSA15_04980

SUW:	SATW20_06410

SUG:	SAPIG0646(hxlB)

SUF:	SARLGA251_05070

SAUA:

SAAG_00992

SAUE:

RSAU_000525

SAUN:

SAKOR_00560

SAUS:

SA40_0512

SAUU:

SA957_0527

SAUG:

SA268_0525

SAUZ:

SAZ172_0573

SAUT:

SAI1T1_2004410

SAUJ:

SAI2T2_1004430

SAUK:

SAI3T3_1004420

SAUQ:

SAI4T8_1004410

SAUV:

SAI7S6_1004420

SAUW:

SAI5S5_1004380

SAUX:

SAI6T6_1004390

SAUY:

SAI8T7_1004420

SAUF:

X998_0613(hxlB)

SAB:

SAB0521

SUY:	SA2981_0548

SAUB:

C248_0646

SAUM:

BN843_5650

SAUC:

CA347_587(hxlB)

SAUR:

SABB_00622(hxlB)

SAUI:

AZ30_02890

SAUD:

CH52_02900

SAMS:

NI36_02845

SUH:	SAMSHR1132_05150

SER:

SERP0217

SEP:

SE_0342

SEPP:

SEB_00263

SEPS:

DP17_1648(hxlB)

SHA:

SH2419

SHH:	ShL2_02214

SSP:	SSP1618 SSP2147

SCA:	SCA_0225 SCA_0710

SLG:	SLGD_02314

SLN:	SLUG_22320

SSD:	SPSINT_0250

SDT:	SPSE_2212(hxlB)

SDP:	NCTC12225_02419(hxlB)

SWA:	A284_00530 A284_10440 A284_12312

SPAS:

STP1_1659

SXY:	BE24_00595

SXL:	SXYLSMQ121_2136

SXO:	SXYL_02290

SHU:	SHYC_10790(hxlB)

SCAP:

AYP1020_2320(hxlB)

SSCH:

LH95_10390

SSCZ:

RN70_11125

SAGQ:

EP23_11370(hxlB)

SEQO:

SE1039_03980

SSIF:

AL483_08725(hxlB)

SCV:	A4G25_06555

SPET:

CEP67_09870(hxlB)

SCOH:

BZ166_02675

SNL:	BJD96_12030

SKL:	C7J89_12600(hxlB)

SFQ:	C7J90_01800(hxlB)

SHOM:

EGX58_03325(hxlB)

SMUS:

C7J88_08350(hxlB)

SCAR:

DWB96_11670(hxlB)

SCHR:

DWB92_10935(hxlB)

SARL:

SAP2_21940

SPIC:

SAMEA4384060_1854(hxlB_1) SAMEA4384060_2298(hxlB_2)

SSH:	NCTC13712_00523(hxlB)

SSIM:

SAMEA4384339_0523(hxlB)

SDB:	CNQ82_05280(hxlB) CNQ82_12850(hxlB)

SLLO:

ISP08_10870(hxlB)

SAUL:

I6G39_01925(hxlB)

SRAI:

LN051_10080(hxlB)

SPSD:

JMB28_11600(hxlB) JMB28_13760(hxlB)

STAS:

HYI43_10890(hxlB)

SURY:

MUA21_01505(hxlB)

SSCU:

CEP64_01025(hxlB)

SFF:	FOB90_09060(hxlB)

MLEN:

H3V22_07280(hxlB)

MVT:	I6J10_09645(hxlB)

MCL:

MCCL_0036

MCAK:

MCCS_00630

MACR:

BHM04_10310

MBRU:

MGG13_01505(hxlB)

MEPI:

KFV12_00625(hxlB)

MEQU:

KFV11_01595(hxlB)

SHV:	AAT16_06525 AAT16_11305

ESI:

Exig_2371

EAN:

Eab7_2215

EXM:	U719_13050

EXU:	ESP131_15160

EACE:

KKI46_12990(hxlB)

PJD:	Pjdr2_1184

GYM:	GYMC10_3884

PPY:

PPE_04674

PPM:	PPSC2_24310(hxlB)

PPO:	PPM_4827(hxlB)

PPOL:

X809_29030 X809_40850

PPQ:	PPSQR21_049260(gutQ)

PPOY:

RE92_12970

PMS:	KNP414_07884

PMQ:	PM3016_7401

PMW:

B2K_37325

PTA:	HPL003_05885

PSAB:

PSAB_01350 PSAB_23290

PDU:	PDUR_01615 PDUR_26630

PBD:	PBOR_34750

PGM:	PGRAT_31060

POD:	PODO_29410

PAEN:

P40081_36065

PAEF:

R50345_29520

PAEQ:

R50912_32675

PSTE:

PSTEL_02010 PSTEL_26040

PAEA:

R70723_31465

PAEE:

R70331_30225

PAEH:

H70357_33730

PAEJ:

H70737_29165

PBJ:	VN24_01050 VN24_04700

PRI:	PRIO_3566 PRIO_6498

PSON:

JI735_07205(hxlB)

PPEO:

ABE82_13080 ABE82_24520

PNP:	IJ22_01450 IJ22_02600

POW:	IJ21_08250

PBV:	AR543_06020 AR543_17155

PXL:	BS614_16305

PYG:	AWM70_20315

PSWU:

SY83_08110

PDH:	B9T62_30295(hxlB)

PIB:	BBD41_28045

PCX:	LPB68_19240

PKB:	B4V02_00900

PAIH:

ASL14_13405

PVO:	PVOR_20954

PLW:	D5F53_10840(hxlB)

PALB:

EJC50_19850(hxlB)

PCHI:

PC41400_00760(hxlB)

PBK:	Back11_48230 Back11_58390

PPRT:

ET464_10970(hxlB)

PBAC:

HUB98_29035(hxlB)

PRZ:	GZH47_09135(hxlB)

PLYC:

GXP70_07135(hxlB)

PSOP:

KP014_01995(hxlB) KP014_04760(hxlB)

PTRI:

KDC22_31570(hxlB)

PALO:

E6C60_2212

PCEL:

HUB94_23395(hxlB)

PTJ:	JRJ22_27895(hxlB)

PKA:	PQ456_03515(hxlB) PQ456_14785(hxlB)

PUI:	PUW25_10545(hxlB) PUW25_26980(hxlB)

PMAH:

PTQ21_17650(hxlB)

PAMY:

P9222_25080(hxlB)

CCHL:

FPL14_17205 FPL14_29075(hxlB)

CHEB:

HH215_35315(hxlB)

SACA:

FFV09_02175(hxlB)

AFX:	JZ786_23540(hxlB)

AACO:

K1I37_20300(hxlB)

ACUR:

JZ785_20930(hxlB)

ADAU:

NZD86_18895(hxlB) NZD86_23125(hxlB)

AFAS:

NZD89_03505(hxlB) NZD89_05665(hxlB) NZD89_23105(hxlB)

EFF:	skT53_30640(hxlB)

PRT:	AUC31_15195

PANA:

BBH88_04825 BBH88_17515

PMAR:

B0X71_02095

PLX:	CW734_09540(hxlB) CW734_13375(hxlB)

PMAT:

BBI11_12875

PDEC:

H1Q58_12155(hxlB)

JEO:	JMA_08730 JMA_29160

SPSY:

AZE41_09420

PANC:

E2636_12240(hxlB)

PLAY:

DNR44_005560

TVU:	AB849_007480(hxlB)

SUB:

SUB0286

SGA:	GALLO_1978

SGG:	SGGBAA2069_c19300(hxlB)

SGT:	SGGB_1961(hxlB)

SPAT:

A0O21_08520

SPOC:

NCTC10925_00226(hxlB)

LAW:	LACWKB8_0787

LKL:	DKL58_01405(hxlB) DKL58_07345(hxlB)

LHS:	DLD54_03665

LPAI:

GYM71_01550 GYM71_09460

LCZ:	LCAZH_0413

LCS:	LCBD_0423 LCBD_0454

LCE:	LC2W_0418 LC2W_0449

LCW:	BN194_04280(hxlB) BN194_04570(hxlB_2)

LCL:	LOCK919_0476

LPQ:	AF91_01145

LPI:	LBPG_03036

LPAP:

LBPC_0349

LCB:	LCABL_04200(phi) LCABL_04500(phi)

LCX:	LCA12A_2396

LRO:	LOCK900_2137

LCHI:

KG086_13080(hxlB)

LZE:	KG087_01985 KG087_13960(hxlB)

LMU:	LBLM1_00430

LLE:	AYR59_00775

FIX:	M8332_02215

FCLI:

M3M38_02175

FHIN:

M3M39_06520

FMT:	M3M35_07065(hxlB)

FCP:	M3M37_03820

LBN:	LBUCD034_0078(hxlB)

LCU:	PL11_004195

LKF:	DNL43_05245(hxlB)

LHIL:

G8J22_00759(rmpB)

LLAO:

LHL71_06160(hxlB)

LBR:

LVIS_0443

LBK:	LVISKB_0450

LCY:	LC20004_14630

AAPI:

MOO46_01975

LPD:	AYR62_06115 AYR62_13390

PCE:

PECL_1749

PACI:

A4V11_00365

LALW:

BTM29_04250

LALI:

LA20249_07460

LBM:	DS830_06210(hxlB)

LHB:	D1010_15410(hxlB)

OOE:

OEOE_0132

OEN:	DSM07_06155(hxlB)

LMM:

MI1_09736

LGC:	A9176_08395

WCB:	AO080_08000 AO080_11065

WJO:	FOL01_0738

WCF:	C6P13_08475(hxlB)

WSO:	WSWS_00758(hxlB)

WHE:	EFA59_09470

WEI:	EQG49_01010(hxlB)

LBE:	MOO44_01765

EFM:

M7W_1509

ECAS:

ECBG_02724

EGV:	EGCR1_00755(hxlB) EGCR1_06785(hxlB) EGCR1_06900

EAV:	EH197_02720 EH197_05790(hxlB) EH197_09435(hxlB) EH197_17125(hxlB)

ESG:	EsVE80_07420

ECEC:

NCTC12421_00422(hxlB)

ERAF:

J9537_02590(hxlB) J9537_09050(hxlB) J9537_17215 J9537_20040

EDS:	PML78_03970

TOO:	C7K38_07920(hxlB) C7K38_08455

VCP:	H9L18_04420(hxlB)

VHY:	G7082_07470(hxlB)

AUR:	HMPREF9243_0241

AUN:	AWM73_08000

AUH:	AWM75_07920

CARN:

FPV25_08820(hxlB)

CAC:

CA_C0397

CAE:

SMB_G0405

CAY:

CEA_G0407

CBE:	Cbei_0530 Cbei_4646

CBZ:	Cbs_0530 Cbs_4646

CBEI:

LF65_06880

CSR:	Cspa_c49600

CDY:	F3K33_23650(hxlB)

CRW:	CROST_007120(hxlB)

CFB:	CLFE_041530(hxlB)

CAUN:

CLAUR_022840(hxlB)

CGEL:

psyc5s11_51550

ACOL:

K5I23_04775(hxlB) K5I23_04785

ROB:	CK5_18940 CK5_18960

LACY:

A4V08_33490

CSCI:

HDCHBGLK_01277(rmpB)

ARF:	AR1Y2_0027 AR1Y2_0499 AR1Y2_1707 AR1Y2_3085 AR1Y2_3234

ACAC:

EYQ97_01655(hxlB) EYQ97_02430(hxlB) EYQ97_09115(hxlB) EYQ97_13050(hxlB) EYQ97_14385

CBOL:

CGC65_09840(hxlB)

SINT:

K5I26_01760(hxlB)

DRU:	Desru_3129

ELIM:

B2M23_10945

CMIU:

B1H56_11565(hxlB)

VGU:	HYG85_22905

TTM:

Tthe_1730

HALS:

D7D81_05745 D7D81_05750(hxlB) D7D81_05790

IFN:	GM661_03200 GM661_03205(hxlB) GM661_03245

HHL:	Halha_2326

KME:	H0A61_02041

SELE:

ADJ74_03835

PUF:

UFO1_0637

PFT:

JBW_00829

FRO:	AALO17_19720

AARG:

Aargi30884_04660(hxlB)

ABSI:

A9CBEGH2_06040(hxlB)

LCG:	L3BBH23_22930(hxlB)

ERB:	A4V01_01275 A4V01_02800 A4V01_19470

CIU:	G4D55_16755(hxlB) G4D55_20090(hxlB) G4D55_20120(hxlB)

SKN:	SKUN_00279

MDX:	BTO20_03340 BTO20_03435 BTO20_30250

MMEH:

M5I08_09485(hxlB)

MTY:	MTOK_48640

MAUB:

MAUB_30790(hxlB)

MMAT:

MMAGJ_12230 MMAGJ_73880(hxlB_1) MMAGJ_74080(hxlB_2)

CDX:	CDES_00565

CCYC:

SCMU_00960(hxlB) SCMU_40770

RHA:	RHA1_ro00488 RHA1_ro11330

ROA:	Pd630_LPD04588

RKO:	JWS14_16850 JWS14_41250

ROZ:	CBI38_29955

RPSK:

JWS13_28025

SRC:	M271_24320

SAMB:

SAM23877_0308(rmpB)

SLE:	sle_59920(sle_59920)

SKY:	D0C37_01170

SDX:	C4B68_02680

SXN:	IAG42_32235(hxlB)

PSIC:

J4E96_11820(hxlB)

CMI:

CMM_1124

CMS:	CMS1444(rmpB)

CMC:

CMN_01093

CMH:	VO01_04535

CCAP:

AES38_05200

CZH:	H9X71_05275

CPHA:

FGI33_07655

CCAF:

FGD68_07730(hxlB)

MIM:	AKG07_11690

MIP:	AXH82_02215

MIH:	BJP65_05200

MICR:

BMW26_16480

MCHN:

HCR76_15235

RIA:	C7V51_11570

RFS:	C1I64_17215(hxlB)

RTE:	GSU10_14410(hxlB)

CUM:	NI26_12480

CUB:	BJK06_08980

CUG:	C1N91_12865(hxlB)

CQF:	GBG65_05945(hxlB)

AGY:	ATC03_10770

AGM:	DCE93_00165(hxlB)

CART:

PA27867_0094

MYL:	C3E77_13390

MSPO:

KXZ72_11835

SALC:

C2138_08150(hxlB)

SALA:

ESZ53_12320

PLAP:

EAO79_07235(hxlB)

HEH:	L3i23_13450

FRN:	F1C15_08055

AGX:	AGREI_3080(rmpB)

ART:

Arth_3709

ARR:	ARUE_c04630(rmpB)

ARE:	AL755_02185 AL755_14015

ARH:	AHiyo8_33950

ARZ:	AUT26_19925

ARU:	ASPU41_06000

ARQ:	BWQ92_09775

ARN:	CGK93_01945(hxlB)

ARX:	ARZXY2_3982(hxlB)

ARTH:

C3B78_00805(hxlB)

ASUN:

KG104_15070(hxlB)

AAU:

AAur_0493

PUE:	FV140_21530(hxlB)

PNV:	JMY29_02265(hxlB)

APN:	Asphe3_02210

PSUL:

AU252_12860

PSEY:

GU243_15485(hxlB)

AAI:	AARI_06570(rmpB)

GAR:	AOZ07_14975

GLU:	F0M17_03410(hxlB)

GMY:	XH9_05405(hxlB)

KPL:	KPaMU14_03845

SATK:

SA2016_1325 SA2016_3450 SA2016_3839

BRX:	BH708_07840

BRR:	C1N80_12900(hxlB)

BKI:	M4486_00585(hxlB)

BHH:	Bra3105_16390(hxlB)

PSEI:

GCE65_00430

PAUS:

NCTC13651_01297(hxlB)

NOW:	GBF35_26635

AMQ:	AMETH_4517(hpi)

ATHM:

L1857_26925

PSEE:

FRP1_13265

PSEQ:

AD006_20945

PECQ:

AD017_00525

MTEM:

GCE86_09295

MCRA:

ID554_09635 ID554_24755

VER:	HUT12_22590

ACTT:

DDD63_03610

BDE:

BDP_0014

BDN:

BBDE_0014

BBV:	HMPREF9228_1869

BBRE:

B12L_1723

BBRV:

B689b_1820

BBRJ:

B7017_1986

BBRC:

B7019_1960

BBRS:

BS27_1782

BBRD:

BBBR_1797

BANG:

BBAG_0933

BGX:	ESN35_00225

BLEM:

BL8807_07055 BL8807_10610

BEU:	BE0216_00790 BE0216_04555(hxlB)

GVG:	HMPREF0421_21239

GVH:	HMPREF9231_0283

AEY:	CDG81_05570

NAB:	B1sIIB91_01965

ATB:	J4859_05600 J4859_15580

CGO:	Corgl_0568

ABAO:

BEQ56_05675 BEQ56_09845

CAP:	CLDAP_06920 CLDAP_16730

MSV:	Mesil_3056

KST:	KSMBR1_1055 KSMBR1_3739

BROC:

IPI25_07160(hxlB) IPI25_12570

BPIT:

BPIT_02080 BPIT_15350

JET:	L3J17_12540 L3J17_14955(hxlB)

UAM:	UABAM_03098

SSM:	Spirs_4205

SBU:	SpiBuddy_2421

TAZ:	TREAZ_1966

BHC:	JFL75_00540

TRS:	Terro_1473

TALB:

FTW19_05085

EDA:	GWR55_03245

STR:	Sterm_1850 Sterm_3213 Sterm_3836

MICA:

P0L94_12765(hxlB)

CPI:

Cpin_5672

CHIH:

GWR21_16305(hxlB)

ARAC:

E0W69_006910(hxlB)

FLN:

FLA_3347

PEP:	AQ505_07145

PCM:	AY601_4887

PSTY:

BFS30_16370

PROE:

H9L23_01685(hxlB)

PMUO:

LOK61_01880(hxlB)

PGJ:	QG516_07770(hxlB)

PSN:	Pedsa_2162

MUP:	A0256_03170

MRUB:

DEO27_000310(hxlB)

MGOS:

DIU38_016635(hxlB)

EVI:	Echvi_3533

EMAI:

KZP23_17985(hxlB)

PKO:	PKOR_19960

FCR:	HYN56_16625(hxlB)

FPLU:

NLG42_16060(hxlB)

ZPR:

ZPR_1062

MARM:

YQ22_17835

CAO:	Celal_3938

CBAL:

M667_16190

CBAT:

M666_16175

ZGA:	ZOBELLIA_3941(hxlB)

LPAL:

LDL79_02285(hxlB)

CBEN:

EG339_11260(hxlB)

CLAC:

EG342_07780

MPG:	Theba_2592

ALAM:

RT761_00647(hxlB_1) RT761_01715(hxlB_2)

MJA:

MJ_1247

MFE:	Mefer_0374

MVU:	Metvu_0392

MFS:	MFS40622_0689

MIF:	Metin_0760

MJH:	JH146_0477

MESG:

MLAUSG7_1287(phi)

MESA:

MLASG1_0489(phi)

MIG:	Metig_1088

MMP:

MMP1270

MMQ:	MmarC5_0321

MMX:	MmarC6_1403

MMZ:	MmarC7_0516

MMD:

GYY_07185

MMAK:

MMKA1_14950

MMAO:

MMOS7_13770

MMAD:

MMJJ_15750(hxlA)

MAE:

Maeo_1163

MVN:	Mevan_0582

MOK:	Metok_0734

METF:

CFE53_04715

MTH:	MTH_1546 MTH_249

MMG:	MTBMA_c01320(phi1) MTBMA_c06990(phi2)

MWO:	MWSIV6_0086 MWSIV6_0661

MTEE:

MTTB_08920 MTTB_15610

METC:

MTCT_0212 MTCT_1411

METE:

tca_00229(hxlB_1) tca_01495(hxlB_2)

METZ:

METMT2_0042 METMT2_0695

METK:

FVF72_01055(hxlB) FVF72_03890(hxlB)

MTHM:

FZP57_00370(hxlB) FZP57_03150(hxlB)

METJ:

FZP68_05365(hxlB) FZP68_08190(hxlB)

MST:

Msp_0247

METB:

AW729_00875 AW729_05950

MRU:	mru_0250(phi1) mru_1310(phi2)

MSI:

Msm_1391

MEB:	Abm4_0150 Abm4_1390

MMIL:

sm9_2187(hxlB)

MEYE:

TL18_00870

MOL:

YLM1_0018

MARO:

MarbSA_13480

METV:

K4897_04350(hxlB)

MEL:	Metbo_0617 Metbo_2522

MEW:	MSWAN_0109 MSWAN_0280 MSWAN_1744

METH:

MBMB1_0100 MBMB1_1368

MFC:	BRM9_0164(hxlB1) BRM9_0593(hxlB2)

MFI:	DSM1535_0575 DSM1535_1482

MCUB:

MCBB_0119 MCBB_1608

MSUB:

BK009_05845 BK009_10325

METN:

BK008_01390 BK008_05945

METT:

CIT01_06195(hxlB) CIT01_07665 CIT01_10335(hxlB)

METO:

CIT02_06520(hxlB) CIT02_11140(hxlB)

MEME:

HYG87_00110(hxlB) HYG87_06565 HYG87_07035(hxlB)

MFV:	Mfer_1158 Mfer_1194

MKA:

MK1663

AFU:	AF_0861 AF_1796

AFG:	AFULGI_00009430 AFULGI_00020470

APO:	Arcpr_0694 Arcpr_0698 Arcpr_1797

AVE:	Arcve_0921 Arcve_1683

AST:	Asulf_00165 Asulf_00326 Asulf_00974

FPL:	Ferp_0376 Ferp_2198

GAC:	GACE_0250 GACE_0818

GAH:	GAH_00051 GAH_01859

PFU:

PF0220

PFI:

PFC_00160

PHO:	PH1938(PH1938)

PAB:

PAB1222

PYN:

PNA2_0868

PYA:	PYCH_13020

PYS:

Py04_0376

PYC:	TQ32_01240

TKO:

TK0475

TON:

TON_0336

TGA:	TGAM_1891(hps)

TSI:

TSIB_0428

TBA:	TERMP_00758

THE:

GQS_03555

THA:

TAM4_82

THM:

CL1_0365

TLT:

OCC_09933

THS:

TES1_0756

TNU:

BD01_0222

TEU:

TEU_06790

TGY:	X802_02210

THV:	ADU37_CDS03570

TPEP:

A0127_02350

TPIE:

A7C91_07685

TGG:	A3K92_01750

TCE:	A3L02_00185

TBS:	A3L01_02370

THH:	CDI07_02325

TSL:	A3L11_06255

TTD:	A3L14_03835

TPRF:

A3L09_00545

TRL:	A3L10_04210

TPAF:

A3L08_04625

THY:	A3L12_06325

TIC:	FH039_04545(hxlA)

TCQ:	TIRI35C_0698

THEM:

FPV09_04565(hxlA)

THEI:

K1720_05250(hxlA)

PPAC:

PAP_05755

MBA:	Mbar_A1170 Mbar_A3132

MBY:	MSBRM_1108 MSBRM_3392

MBW:	MSBRW_1605 MSBRW_3553

MBAR:

MSBR2_1304 MSBR2_3345

MBAK:

MSBR3_0600 MSBR3_3372

MAC:	MA_1384 MA_4504

MMA:	MM_1215 MM_2367

MMAZ:

MmTuc01_1255 MmTuc01_2419

MMJ:	MSMAS_0097 MSMAS_2332

MMAC:

MSMAC_0105 MSMAC_2113

MVC:	MSVAZ_0103 MSVAZ_1860

MEK:	MSKOL_0099 MSKOL_1847

MLS:	MSLAZ_0967 MSLAZ_3053

METM:

MSMTP_0201 MSMTP_2178

MEF:	MSWH1_2160 MSWH1_3047

MEQ:	MSWHS_1919 MSWHS_2937

MSJ:	MSSAC_1390 MSSAC_4300

MSZ:	MSSIH_1568 MSSIH_3802

MSW:	MSSIT_1678 MSSIT_3879

MTHR:

MSTHT_0838 MSTHT_1664

MTHE:

MSTHC_1625 MSTHC_2433

MHOR:

MSHOH_0117 MSHOH_2954

MFZ:	AOB57_007440 AOB57_012310(hxlB)

MBU:

Mbur_1889

MMET:

MCMEM_0118 MCMEM_0644

MELO:

J7W08_01295 J7W08_10660(hxlB)

MMH:	Mmah_1222 Mmah_1869

MHAZ:

BHR79_04305 BHR79_07435

MEV:	Metev_0697 Metev_1774

MZH:	Mzhil_0311 Mzhil_1920

MPY:	Mpsy_1396 Mpsy_1625

MZI:	HWN40_00620(hxlB) HWN40_01805

MHZ:	Metho_0199 Metho_0283

MTP:

Mthe_0455

MCJ:

MCON_0429

MHI:

Mhar_1869

MHU:	Mhun_0647 Mhun_0910 Mhun_3031

MRTJ:

KHC33_01740 KHC33_09160(hxlB) KHC33_10130

MLA:	Mlab_0993 Mlab_1453

MEM:	Memar_0706 Memar_0744 Memar_1507

MBG:	BN140_0695(hps) BN140_1140 BN140_1177

MEMA:

MMAB1_0908(hps) MMAB1_1456(hpsA) MMAB1_1494

MCHK:

MchiMG62_08290 MchiMG62_08670 MchiMG62_16740(hxlB)

MSUM:

OH143_01745(hxlB) OH143_10250 OH143_10440

MPI:	Mpet_0160 Mpet_0679 Mpet_1329

MEND:

L6E24_05200 L6E24_07265 L6E24_12570(hxlB)

MAQE:

RJ40_01760(hxlB) RJ40_11130

MOU:	OU421_07500(hxlB) OU421_09050 OU421_10910(hxlB)

MANQ:

L1994_04215(hxlB) L1994_08160 L1994_10205(hxlB)

MBN:	Mboo_0707 Mboo_1199

MFO:	Metfor_1005 Metfor_1449 Metfor_2503

MPL:	Mpal_2121 Mpal_2411

MPD:

MCP_0861

MEZ:

Mtc_1411

RCI:	RCIX1492 RRC413

MELU:

MTLP_11470 MTLP_12130

MEAM:

MU439_04450(hxlB) MU439_06385

TAR:	TALC_01384 TALC_01565

MAX:	MMALV_14810 MMALV_16840

MER:	MMINT_16580 MMINT_19420

MEAR:

Mpt1_c00380(phi) Mpt1_c14440(faeB)

MEUZ:

KRP56_00255 KRP56_07190

MARC:

AR505_0014 AR505_0177

ABI:	Aboo_0457 Aboo_0638

ACF:	AciM339_0396 AciM339_0590

APE:	APE_1940.1(hxlB)

ACJ:	ACAM_1213(hxlB)

SMR:

Smar_0385

SHC:	Shell_0416

IHO:

Igni_0788

IIS:

EYM_02670

IPC:

IPA_08880

DKA:

DKAM_0222

DFD:	Desfe_0297

DMU:	Desmu_0950

TAG:

Tagg_0275

IAG:

Igag_1421

THG:	TCELL_0643

HBU:

Hbut_1240

PFM:	Pyrfu_0251

PDL:	Pyrde_0680 Pyrde_1086

STO:	STK_01980(hxlB)

SOH:	D1869_00465(hxlB)

SSO:	SSO0151(hpS-1)

SOL:

Ssol_1130

SSOA:

SULA_1166(hxlB)

SSOL:

SULB_1167(hxlB)

SSOF:

SULC_1165(hxlB)

SSHI:

J5U23_00112

SCAS:

SACC_00650

SAI:

Saci_0747

SACN:

SacN8_03630

SACR:

SacRon12I_03615

SACS:

SUSAZ_03345

SIS:	LS215_2152

SIA:	M1425_1987

SIM:	M1627_2065

SID:

M164_1993

SIY:	YG5714_2110

SIN:	YN1551_0808

SIH:

SiH_1931

SIR:

SiRe_1858

SIC:

SiL_1840

SULA:

BFU36_05175

SULE:

GFS03_10880(hxlB)

SULO:

GFS33_02695(hxlB)

SULL:

EWF20_01905(hxlB)

MSE:

Msed_0236

MEMJ:

MJ1HA_0322

MCN:

Mcup_1836

MHK:	DFR87_05675(hxlB)

MPRU:

DFR88_05435(hxlB)

MTEN:

GWK48_06310(hxlB)

MJN:	MjAS7_0845

AHO:

Ahos_0880

AMAN:

B6F84_08250

ABRI:

DFR85_06600(hxlB)

ASUL:

DFR86_07265(hxlB)

AAMB:

D1866_12295(hxlB)

ACIH:

HS5_22550

SACD:

HS1genome_1278

SAZO:

D1868_01610(hxlB)

CSTY:

KN1_18200

STEP:

IC006_1899

SAHS:

HS7_18470

PAI:

PAE1489

PIS:

Pisl_1579

PCL:

Pcal_0808

PAS:

Pars_0616

PYR:

P186_2755

POG:

Pogu_1737

TNE:

Tneu_0610

PYW:	PYWP30_00629

CMA:

Cmaq_0308

TTN:	TTX_1049(phi)

TUZ:

TUZN_0737

VDI:

Vdis_1032

VMO:

VMUT_1868

VSO:	Vsou_10130

TPE:

Tpen_0479

THB:	N186_03370

TCB:	TCARB_1741

THF:	MA03_06735

THEL:

IG193_04665(hxlB)

ASC:

ASAC_0446

ACIA:

SE86_03105

CLG:	Calag_1357

FFO:	FFONT_0850

NCV:

NCAV_0256

CCAI:

NAS2_0505

KCR:

Kcr_1608

BARC:

AOA65_1432(phi)

BARB:

AOA66_0272(phi) AOA66_0495

FLT:	Sv326_1041

» show all

Reference

1 [PMID:4219834]

Authors

Ferenci T, Strom T, Quayle JR

Title

Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus.

Journal

Biochem J 144:477-86 (1974)
DOI:10.1042/bj1440477

Reference

2 [PMID:16278835]

Authors

Yurimoto H, Kato N, Sakai Y

Title

Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism.

Journal

Chem Rec 5:367-75 (2005)
DOI:10.1002/tcr.20056

Reference

3 [PMID:16428816]

Authors

Kato N, Yurimoto H, Thauer RK

Title

The physiological role of the ribulose monophosphate pathway in bacteria and archaea.

Journal

Biosci Biotechnol Biochem 70:10-21 (2006)
DOI:10.1271/bbb.70.10

Reference

4 [PMID:15901685]

Authors

Orita I, Yurimoto H, Hirai R, Kawarabayasi Y, Sakai Y, Kato N

Title

The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway.

Journal

J Bacteriol 187:3636-42 (2005)
DOI:10.1128/JB.187.11.3636-3642.2005

Reference

5 [PMID:11839305]

Authors

Martinez-Cruz LA, Dreyer MK, Boisvert DC, Yokota H, Martinez-Chantar ML, Kim R, Kim SH

Title

Crystal structure of MJ1247 protein from M. jannaschii at 2.0 A resolution infers a molecular function of 3-hexulose-6-phosphate isomerase.

Journal

Structure 10:195-204 (2002)
DOI:10.1016/S0969-2126(02)00701-3

Sequence

[mja:MJ_1247]

Reference

6 [PMID:11468398]

Authors

Taylor EJ, Charnock SJ, Colby J, Davies GJ, Black GW

Title

Cloning, purification and characterization of the 6-phospho-3-hexulose isomerase YckF from Bacillus subtilis.

Journal

Acta Crystallogr D Biol Crystallogr 57:1138-40 (2001)
DOI:10.1107/S090744490100748X

Other DBs

ExplorEnz - The Enzyme Database:

5.3.1.27

IUBMB Enzyme Nomenclature:

5.3.1.27

ExPASy - ENZYME nomenclature database:

5.3.1.27

BRENDA, the Enzyme Database:

5.3.1.27

DBGET integrated database retrieval system