| Entry |
|
|---|
| Name |
TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase (dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose-forming);
dTDP-6-deoxy-hex-4-ulose isomerase;
TDP-6-deoxy-hex-4-ulose isomerase;
FdtA
|
|---|
| Class |
Isomerases;
Intramolecular oxidoreductases;
Interconverting keto- and enol-groups
|
|---|
| Sysname |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose:dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose isomerase
|
|---|
| Reaction(IUBMB) |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose = dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose [RN: R09904]
|
|---|
| Reaction(KEGG) |
|
|---|
| Substrate |
dTDP-4-dehydro-6-deoxy-alpha-D-glucopyranose [CPD: C11907]
|
|---|
| Product |
dTDP-3-dehydro-6-deoxy-alpha-D-galactopyranose [CPD: C19960]
|
|---|
| Comment |
The enzyme is involved in the biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose. Four moieties of alpha-D-rhamnose and two moities of 3-acetamido-3,6-dideoxy-alpha-D-galactose form the repeating unit of the glycan chain in the S-layer of the bacterium Aneurinibacillus thermoaerophilus.
|
|---|
| History |
EC 5.3.2.3 created 2011
|
|---|
| Pathway |
| ec00523 | Polyketide sugar unit biosynthesis |
| ec00541 | O-Antigen nucleotide sugar biosynthesis |
| ec01110 | Biosynthesis of secondary metabolites |
|
|---|
| Orthology |
| K20679 | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase |
|
|---|
| Reference |
|
|---|
| Authors |
Pfoestl A, Hofinger A, Kosma P, Messner P |
|---|
| Title |
Biosynthesis of dTDP-3-acetamido-3,6-dideoxy-alpha-D-galactose in Aneurinibacillus thermoaerophilus L420-91T. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Reference |
|
|---|
| Authors |
Davis ML, Thoden JB, Holden HM |
|---|
| Title |
The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase. |
|---|
| Journal |
|
|---|
| Sequence |
|
|---|
| Other DBs |
| ExplorEnz - The Enzyme Database: | 5.3.2.3 |
| ExPASy - ENZYME nomenclature database: | 5.3.2.3 |
| BRENDA, the Enzyme Database: | 5.3.2.3 |
|
|---|
