KEGG   ENZYME: 6.2.1.64
Entry
EC 6.2.1.64                 Enzyme                                 
Name
E1 NEDD8-activating enzyme;
NEDD-activating enzyme E1;
NAE1 (gene name);
UBA3 (gene name)
Class
Ligases;
Forming carbon-sulfur bonds;
Acid-thiol ligases
Sysname
[NEDD8 protein]:[E1 NEDD8-activating enzyme] ligase (AMP-forming)
Reaction(IUBMB)
ATP + [NEDD8 protein] + [E1 NEDD8-activating enzyme]-L-cysteine = AMP + diphosphate + [E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine
Substrate
ATP [CPD:C00002];
[NEDD8 protein];
[E1 NEDD8-activating enzyme]-L-cysteine
Product
AMP [CPD:C00020];
diphosphate [CPD:C00013];
[E1 NEDD8-activating enzyme]-S-[NEDD8 protein]-yl-L-cysteine
Comment
Some RING-type E3 ubiquitin transferase (EC 2.3.2.27) are not able to bind a substrate protein directly. Instead, they form complexes with a cullin scaffold protein and a substrate recognition module, which are known as CRL (Cullin-RING-Ligase) complexes. The cullin protein needs to be activated by the ubiquitin-like protein NEDD8 in a process known as neddylation. Like ubiquitin, the NEDD8 protein ends with two glycine residues. The E1 NEDD8-activating enzyme activates NEDD8 in an ATP-dependent reaction by forming a high-energy thioester intermediate between NEDD8 and one of its cysteine residues. The activated NEDD8 is subsequently transferred to a cysteine residue of EC 2.3.2.34, E2 NEDD8-conjugating enzyme, and is eventually conjugated to a lysine residue of specific substrates in the presence of the appropriate E3 transferase (EC 2.3.2.32, cullin-RING-type E3 NEDD8 transferase).
History
EC 6.2.1.64 created 2020
Orthology
K10686  NEDD8-activating enzyme E1
Genes
HSA9039(UBA3)
PTR460496(UBA3)
PPS100970386(UBA3)
GGO101131301(UBA3)
PON100173204(UBA3)
NLE100597986(UBA3)
MCC696493(UBA3)
MCF102116964(UBA3)
MTHB126948868
CSAB103227873(UBA3)
CATY105585673(UBA3)
PANU101013877(UBA3)
TGE112619769(UBA3)
RRO104677916(UBA3)
RBB108520119(UBA3)
TFN117083116(UBA3)
PTEH111533449(UBA3)
CANG105515358(UBA3)
CJC100392131(UBA3)
SBQ101046690(UBA3)
CSYR103267438(UBA3)
MMUR105857801(UBA3)
LCAT123623015(UBA3)
PCOQ105819504(UBA3)
OGA100946690(UBA3)
MMU22200(Uba3)
MCAL110295730(Uba3)
MPAH110314225(Uba3)
RNO117553(Uba3)
MCOC116099314(Uba3)
MUN110551651(Uba3)
CGE100756784(Uba3)
MAUA101822384(Uba3)
PLEU114681788(Uba3)
MORG121439310(Uba3)
MFOT126506055
AAMP119806686(Uba3)
NGI103729144(Uba3)
HGL101716749(Uba3)
CPOC100720892(Uba3)
CCAN109691366(Uba3)
DORD105981270(Uba3)
DSP122108015(Uba3)
NCAR124970949
OCU100343309
OPI101516338
TUP102498293(UBA3)
GVR103586068(UBA3)
CFA476560(UBA3)
CLUD112666049(UBA3)
VVP112909129(UBA3)
VLG121494765(UBA3)
AML100479609(UBA3)
UMR103674240(UBA3)
UAH113257069(UBA3)
UAR123799132(UBA3)
ELK111144033
LLV125109959
MPUF101679293(UBA3)
ORO101370625(UBA3)
EJU114214597(UBA3)
ZCA113916945(UBA3)
MLX118005781(UBA3)
NSU110585012(UBA3)
LWW102741687(UBA3)
FCA101090175(UBA3)
PYU121016734(UBA3)
PBG122487420(UBA3)
LRUF124524984
PTG102959349(UBA3)
PPAD109279028(UBA3)
AJU106975135(UBA3)
HHV120242879(UBA3)
BTA512647(UBA3)
BOM102280651(UBA3)
BIU109576168(UBA3)
BBUB102414641(UBA3)
BBIS105004391(UBA3)
CHX102176174(UBA3)
OAS101116609(UBA3)
ODA120868411(UBA3)
CCAD122425133(UBA3)
SSC100153428(UBA3)
CFR102520733(UBA3)
CBAI105066590(UBA3)
CDK105095258(UBA3)
VPC102533039(UBA3)
BACU103020006(UBA3)
LVE103072527(UBA3)
OOR101276676(UBA3)
DLE111174201(UBA3)
PCAD102975529(UBA3)
PSIU116761556(UBA3)
ECB100053395(UBA3)
EPZ103550877(UBA3)
EAI106827923(UBA3)
MYB102248175(UBA3)
MYD102751534(UBA3)
MMYO118667899(UBA3)
MLF102427034(UBA3)
MNA107524035(UBA3)
PKL118715019(UBA3)
HAI109392528(UBA3)
DRO112301217(UBA3)
SHON118983430(UBA3)
AJM119038290(UBA3)
PDIC114501565(UBA3)
PHAS123814516(UBA3)
MMF118633446(UBA3)
RFQ117036802(UBA3)
PALE102878332(UBA3)
PGIG120593789(UBA3)
PVP105291000(UBA3)
RAY107497447(UBA3)
MJV108395823(UBA3)
TOD119230920(UBA3) 119244539
SARA101550085(UBA3)
LAV100670330(UBA3)
TMU101353473
ETF101659412(UBA3)
DNM101429109(UBA3)
MDO100011849(UBA3)
GAS123234904(UBA3)
SHR100930499(UBA3)
PCW110222518(UBA3)
OAA100078310(UBA3)
GGA426073(UBA3)
PCOC116237074(UBA3)
MGP100550920(UBA3)
CJO107319855(UBA3)
NMEL110404630(UBA3)
APLA101796590(UBA3)
ACYG106035439(UBA3)
AFUL116492866(UBA3)
TGU100222658(UBA3)
LSR110481965(UBA3)
SCAN103817086(UBA3)
PMOA120495706(UBA3)
OTC121347350(UBA3)
PRUF121351716(UBA3)
GFR102042013(UBA3)
FAB101809994(UBA3)
PHI102113491(UBA3)
PMAJ107210284(UBA3)
CCAE111934974(UBA3)
CCW104683361(UBA3)
CBRC103624361(UBA3)
ETL114063092(UBA3)
ZAB102063494(UBA3)
ACHL103810787(UBA3)
FPG101922859(UBA3)
FCH102050724(UBA3)
CLV102092543(UBA3)
EGZ104132662(UBA3)
NNI104016925(UBA3)
PLET104614291(UBA3)
PCRI104030452(UBA3)
PCAO104048769(UBA3)
ACUN113484714(UBA3)
TALA104355826(UBA3)
PADL103921789(UBA3)
AFOR103903218(UBA3)
ACHC115353896(UBA3)
HALD104310713(UBA3)
HLE104833813(UBA3)
AGEN126049823
GCL127021653
CCRI104155173(UBA3)
CSTI104558124(UBA3)
EHS104503372(UBA3)
CMAC104484578(UBA3)
MUI104537692(UBA3)
FGA104069945(UBA3)
GSTE104256238(UBA3)
LDI104340452(UBA3)
MNB103779410(UBA3)
OHA104331345(UBA3)
NNT104399684(UBA3)
DPUB104308029(UBA3)
PGUU104458399(UBA3)
ACAR104518221(UBA3)
CPEA104388080(UBA3)
AVIT104267929(UBA3)
CVF104285168(UBA3)
CUCA104061210(UBA3)
TEO104383296(UBA3)
BRHI104490802(UBA3)
AAM106494568(UBA3)
AROW112970427(UBA3)
NPD112958769(UBA3)
TGT104566032(UBA3)
DNE112989616(UBA3)
SCAM104146578(UBA3)
ASN102382320(UBA3)
AMJ102576483(UBA3)
CPOO109311184(UBA3)
GGN109288984(UBA3)
PSS102448642(UBA3)
CMY102946017(UBA3)
CPIC101946322(UBA3)
TST117880317(UBA3)
CABI116820408(UBA3)
MRV120409067(UBA3)
ACS100566540(uba3)
PVT110083321(UBA3)
SUND121922522(UBA3)
PBI103067708(UBA3)
PMUR107302647(UBA3)
CTIG120301415(UBA3)
PGUT117679010(UBA3)
VKO123034423(UBA3)
PMUA114591846(UBA3)
ZVI118080826(UBA3)
GJA107121810(UBA3)
STOW125429390(UBA3)
XLA108714725(uba3.L) 734782(uba3.S)
XTR100124303(uba3)
NPR108786184(UBA3)
RTEM120945216(UBA3)
BBUF120978457(UBA3)
BGAR122943174(UBA3)
DRE406776(uba3)
SRX107729399 107737645 107753775
SANH107656056 107672020 107696817
SGH107558885 107580149 107600288
CCAR109061212 109061224 109077613
CAUA113055001 113069100 113111027
PPRM120480798(uba3)
MAMB125256805(uba3)
IPU108276284(uba3)
PHYP113530732(uba3)
SMEO124399227(uba3)
TFD113641820(uba3)
AMEX103047072(uba3)
EEE113575467(uba3)
TRU101073510(uba3)
TNGGSTEN00023614G001
LCO104932180 104933148
NCC104944983 104955224(uba3)
CGOB115008263 115011383
ELY117256264(uba3) 117258904
EFO125891409 125893796(uba3)
PLEP121946477 121949671(uba3)
SLUC116035189(uba3) 116061992
ECRA117943434(uba3) 117947055
ESP116688231 116692315
PFLV114554110 114558205
GAT120828986 120835094(uba3)
PPUG119194095(uba3) 119222001
MSAM119886654(uba3) 119906123
CUD121506998(uba3) 121516911
ALAT119021901(uba3) 119022861
MZE101476589 101484655
ONL100698283 100707169
OAU116310945 116330178(uba3)
OLA101162521 101166718
OML112145215(uba3) 112158859
XMA102225974 102230113(uba3)
XCO114136204 114148852
XHE116710013 116731721
PRET103465053 103467665
PFOR103144012 103152910
PLAI106934653 106953339
PMEI106903451 106907052
GAF122832545 122834364(uba3)
CVG107083893 107091497
CTUL119782023 119789537
GMU124856575(uba3) 124870880
NFU107385429(uba3) 107396417
KMR108231938 108241173(uba3)
ALIM106518515(uba3) 106519301
NWH119411712(uba3) 119416830
AOCE111572109 111588779
MCEP125005552 125007431(uba3)
CSEM103385348(uba3)
POV109628897 109634985
SSEN122768622 122777873
HHIP117761467(uba3) 117764866
HSP118105365(uba3) 118111501
LCF108882131 108885652
SDU111221754 111238188
SLAL111655022 111670887
XGL120783499(uba3) 120803892
HCQ109514986(uba3)
BPEC110164522(uba3)
MALB109955907 109966755
BSPL114856283(uba3) 114859396
SASA100196693(uba3) 106567275(uba3) 106572411
STRU115150783 115168117(uba3)
OTW112221944 112254425
OMY110492159 110527957
OGO124031431 124032034 124045894
ONE115102333 115138151
SALP111966608 111969932 111976991
SNH120058867 120061175 120065095
CCLU121538490 121545638 121578473
ELS105013730(uba3)
SFM108923369(uba3) 108940090
PKI111834526 111842277
AANG118211872(uba3)
LOC102696967(uba3)
PSPA121297887 121329119
ARUT117411901 117413772
PSEX120540325(uba3)
LCM102351153(UBA3)
CMK103179785(uba3)
RTP109910816
BFO118416033
BBEL109469372
CIN100183602
SCLV120346172
SPU587059
APLC110974227
AJC117105748
SKO100373014
DMEDmel_CG13343(Uba3)
DER6549271
DSE6609061
DSIDsimw501_GD10991(Dsim_GD10991)
DYADyak_GE12570
DAN6496553
DSR110189787
DPO4805147
DPE6592772
DMN108159139
DWI6640603
DGR6560483
DMODmoj_GI18642
DNV108654828
DHE111595571
DVI6625144
CCAT101450858
BOD106618812
RZE108363382 108376183
MDE101890977
SCAC106094881
LCQ111684814
LSQ119609110
HIS119648263
AGAAgaP_AGAP005102
ACOZ120951241
AARA120896623
ASTE118509703
AAG5576075
AALB109408519
CQUCpipJ_CPIJ015388 CpipJ_CPIJ016052
CPII120413247
CNS116339161
BCOO119079276
AME409394
ACER108003379
ALAB122712474
BIM100747873
BBIF117204173
BVK117235773
BVAN117159613
BTER100652110
BPYO122567152
OBB114872519
MGEN117226522
NMEA116432515
CGIG122397537
SOC105205629
MPHA105830846
AEC105148880
PBAR105431396
VEM105560517
HST105192144
DQU106741184
CFO105255554
FEX115245969
LHU105677677
PGC109853599
OBO105281424
PCF106791679
PFUC122515207
VPS122636139
NVI100117161
CSOL105368140
TPRE106651378
MDL103572349 106693822
CGLO123275323
FAS105268277
DAM107045806
AGIF122854345
CINS118066728
LHT122505454
CCIN107265036
TCA658164
DPA109543973
SOY115881957
ATD109599807
CSET123318626
AGB108917192
LDC111503267
NVL108563720
APLN108741658
PPYR116164551
OTU111421729 111423249
BMOR101738474
BMAN114243594
MSEX115444055
DPLKGM_209010
BANY112048968
NIQ126768957
PMAC106718095
PPOT106103760
PXU106114886 106115075 106115189 106115597 106120494 106122710
PRAP110996453
PBX123714387
PNAP125063560
ZCE119838383
CCRC123693346
HAW110374907
HZE124631805
TNL113500630 113506420
SLIU111355503
OFU114358561
PXY105385156 105388058
CFEL113389120
API100163526
DNX107169124
AGS114122474 114122478
RMD113552002
BTAB109042585
DCI103510542
CLEC106664650
HHAL106686956
NLU111046840
PHUPhum_PHUM050970
FOC113209089
TPAL117650068
ZNE110841305
CSEC111868238
SGRE126293670 126318312
FCD110856139
DPXDAPPUDRAFT_198149
DMK116929816
DPZ124311834
PVM113828240
PJA122248167
PCHN125027017
HAME121869689
PCLA123769946
PTRU123501265
HAZT108673009 108677282
EAF111711538
LSM121122386
PPOI119107499 119108610
ISCIscW_ISCW015506
DSV119446177
RSAN119389981
RMP119174588
VDE111246574
VJA111262030
TUT107361193
DPTE113793782
DFR124490163
CSCU111635613
PTEP107446217
SDM118190775
CELCELE_F11H8.1(rfl-1)
CBRCBG_16503(Cbr-rfl-1)
BMYBM_BM3316(Bma-rfl-1)
LOALOAG_01766
NAINECAME_02540
TSPTsp_09278
HROHELRODRAFT_106596
LGILOTGIDRAFT_116743
PCAN112571589
BGT106080113
GAE121367643
HRF124151800
HRJ124277507
CRG105328387
MYI110454458
PMAX117331340
MMER123530526
OBI106883626
OSN115210620
LAK106180312
SMMSmp_211070
OVIT265_08127
NVE5513412
EPA110249842
ATEN116300406
ADF107352992
AMIL114977759
PDAM113673942
SPIS111329540
DGT114516422
XEN124436357
HMG105848799
TADTRIADDRAFT_25845
AQU100634480
ATHAT5G19180(ECR1)
ALY9310005
CRB17883419
CSAT104706240 104735980 104770273
EUSEUTSA_v10013467mg
BRP103845774 103856370
BNA106384458 106386769 106433658 106434242 111206274
BOE106312911 106336158
RSZ108814173 108843944
THJ104818804
CPAP110808274
CIT102610024
CICCICLE_v10006509mg
PVY116135019 116135078
MINC123221629
TCC18602917
GRA105800495
GHI107941834 121206329
GAB108454051
DZI111279842 111307932
EGR104414871
GMX100803924 100808837
GSJ114393607 114420146
PVUPHAVU_003G091500g
VRA106765627
VAR108323829
VUN114178692
CCAJ109809469
APRC113874089
MTR11436326
CAM101506033
PSAT127138395
LJALj4g3v2400830.1(Lj4g3v2400830.1)
ADU107482638
AIP107638602
AHF112741184 112795883
LANG109329614 109329616 109337793
FVE101302406 101310403
RCN112200492
PPER18792137
PMUM103322816
PAVI110770328
PDUL117614697
MDM103403897 103453080
PXB103930817 103954118
ZJU107423017 107423260
MNT21390750
CSV101209336
CMO103483734
BHJ120085702
MCHA111009338
CMAX111479191
CMOS111457804
CPEP111791304
RCU8271591
JCU105631932
HBR110655221 110657772
MESC110601552 110611230
POP7454255 7497959
PEU105116876 105118127
PALZ118029704 118061045 118062744
JRE109010475
CILL122274708
QSU112016961 112035240
QLO115995194
TWL119981082 120014398
VVI100256207
VRI117914357
SLY101252115
SPEN107007881
SOT102584079
SSTN125877058
CANN107841216
NTA107811436
NSY104228308
NTO104084891
NAU109212959
INI109175758
ITR116002925
SIND105171382
OEU111392964
EGT105953246
SSPL121783630 121797418 121799575 121808475
APAN127248573
HAN110918326
ECAD122591261
LSV111881621
CCAV112505715
DCR108193284 108199866
CSIN114316179
BVG104907952
SOE110800550
CQI110716029 110725918
NNU104596446
MING122090563
TSS122642911
PSOM113336889 113357346
OSA4325169
DOSAOs01t0271500-01(Os01g0271500)
OBR102706977
BDI100838283
ATS109786876
TDC119267978 119275843
TAES123061091 123069678 123078164
TUA125543715 125543716 125543717
LPER127342473
SBI8074525
ZMA100283559
SITA101786734
SVS117858615
PVIR120673559 120706510
PHAI112895491
PDA103712331
EGU105060447
MUS103995359
ZOF121989459 121998404
DCT110103662
PEQ110025914
AOF109848222
NCOL116264697
ATR18440540
SMOSELMODRAFT_106904 SELMODRAFT_174709
PPP112274550 112295736
CRECHLRE_12g491500v5
VCNVOLCADRAFT_109881
CSLCOCSUDRAFT_53737
CVRCHLNCDRAFT_144742
APROF751_5208
OLUOSTLU_30829
OTAOT_ostta03g05020
BPGBathy07g00940
MISMICPUN_52640
MPPMICPUCDRAFT_3065
CMECYME_CMM282C
GSLGasu_48770
CCPCHC_T00008644001
SCEYPR066W(UBA3)
SEUBDI49_5518
SPAOSPAR_P03220
AGOAGOS_ADL333C
ERCEcym_3471
KLAKLLA0_B09526g
KMXKLMA_80286(UBA3)
LTHKLTH0F10714g
VPOKpol_1065p21
ZROZYRO0C16258g
CGRCAGL0D01518g
NCSNCAS_0A11140(NCAS0A11140)
NDINDAI_0A05160(NDAI0A05160)
TPFTPHA_0A03600(TPHA0A03600)
TBLTBLA_0H01590(TBLA0H01590)
TGBHG536_0B02220
TDLTDEL_0C04980(TDEL0C04980)
KAFKAFR_0H00930(KAFR0H00930)
KNGKNAG_0H00670(KNAG0H00670)
ZMKHG535_0A02280
PPAPAS_chr2-1_0152
DHADEHA2G05126g
PICPICST_46734
PGUPGUG_02938
SPAASPAPADRAFT_52389
LELLELG_04636
CALCAALFM_C600500CA(CaO19.4209)
CTPCTRG_02993
COTCORT_0F04590
CDUCD36_60430
CTENCANTEDRAFT_122668
YLIYALI0F04147g
CLUCLUG_01568
CLUSA9F13_13g00077
CAURCJI97_000517
SLBAWJ20_1337(UBA3)
PKZC5L36_0B01730
BNNFOA43_001710
BBRXBRETT_004798
OPAHPODL_00528
NCRNCU02532
NTENEUTE1DRAFT133618(NEUTE1DRAFT_133618)
SMPSMAC_05822
PANPODANSg10138
TTTTHITE_2114057
MTMMYCTH_2313559
CTHRCTHT_0057060
MGRMGG_09283
PPEIPpBr36_07621
TMNUCRPA7_125
SSCKSPSK_05272
FGRFGSG_00364
FPUFPSE_00023
FVRFVEG_00818
FOXFOXG_00693
NHENECHADRAFT_90199
TRETRIREDRAFT_105192
TRRM419DRAFT_127386
MAWMAC_08816
MAJMAA_04332
CMTCCM_02249
PLJVFPFJ_05220
VALVDBG_04701
VDAVDAG_04243
CFJCFIO01_04953
CLUPCLUP02_05249
CHIGCH63R_00420
SAPOSAPIO_CDS3592
ELAUCREL1_9848
PFYPFICI_01102
SSLSS1G_02960
BFUBCIN_06g05650
MBEMBM_02447
PSCOLY89DRAFT_693715
GLZGLAREA_00800
ANIAN2416.2
AFMAFUA_2G13730
ACTACLA_073910
NFINFIA_088910
AORAO090026000227
ANGANI_1_758024(An02g05450)
AFVAFLA_006072
ALUCAKAW2_21167A
ACHEACHE_50793S
APUUAPUU_20814A
PCSPc12g12240
PDPPDIP_78830
TMFPMAA_035010
TRGTRUGW13939_05330
CIMCIMG_04635
CPWCPC735_071720
UREUREG_01834
PBLPAAG_05733
PBNPADG_07656
ABEARB_04414
TVETRV_06254
AJEHCAG_04625
BGHBDBG_04589
PNOSNOG_04358
PTEPTT_10042
BZECOCCADRAFT_2848
BSCCOCSADRAFT_161852
BORCOCMIDRAFT_6230
AALTCC77DRAFT_960679
ZTRMYCGRDRAFT_86279
PFJMYCFIDRAFT_50749
FFUCLAFUR5_08374
BCOMBAUCODRAFT_542044
NPAUCRNP2_4215
TMLGSTUM_00010688001
SPOSPAC24H6.12c(uba3)
CNECNC02000
CNBCNBC5240
CNGCNAG_01692
CGICGB_C3070C
TMSTREMEDRAFT_35200
TASAA1Q1_02965
TVSTRAVEDRAFT_164597
DSQDICSQDRAFT_132216
PCOPHACADRAFT_256177
SHSSTEHIDRAFT_51350
HIRHETIRDRAFT_415036
PSQPUNSTDRAFT_53600
ADLAURDEDRAFT_110037
FMEFOMMEDRAFT_168918
GTRGLOTRDRAFT_72613
LBCLACBIDRAFT_188073
CCICC1G_01191
ABPAGABI1DRAFT111125(AGABI1DRAFT_111125)
ABVAGABI2DRAFT190343(AGABI2DRAFT_190343)
PCUBJR316_0003594
MPRMPER_03226
MRRMoror_7962
MOREE1B28_008925
SCMSCHCO_02607608(SCHCODRAFT_02607608)
CPUTCONPUDRAFT_97733
SLASERLADRAFT_481008
WSEWALSEDRAFT_20245
WICJ056_001458
UMAUMAG_11204
PFPPFL1_02112
MGLMGL_0174
MRTMRET_1144
MSYMMSY001_0551
PGRPGTG_00608 PGTG_17926 PGTG_20639
MLRMELLADRAFT_118283
EINEint_090820
EHEEHEL_090830
EROEROM_091260
MBRMONBRDRAFT_34910
SREPTSG_00344
DDIDDB_G0283891(ube1c)
DPPDICPUDRAFT_148650
DFADFA_07215(ube1c)
EHIEHI_098550(19.t00019)
EDIEDI_295260
EIVEIN_309560
ACANACA1_288000
PFAPF3D7_0817000
PFDPFDG_00868
PREIPRSY57_0816300
PGABPGSY75_0817000
PYOPY17X_0714000
PCBPCHAS_0722900
PBEPBANKA_0713800
PVVPVVCY_0701360
PKNPKNH_0503400
PVXPVX_089560
PCYPCYB_052480
TANTA20100
TPVTP01_0601
TOTTOT_010000569
BEQBEWA_045340
BBOBBOV_I001030
BBIGBBBOND_0300120
CPVcgd8_1730
CHOChro.80201
TGOTGME49_264880
TETTTHERM_00185350
PTMGSPATT00018275001
PTIPHATRDRAFT_33774(UBA3)
FCYFRACYDRAFT_275518
TPSTHAPSDRAFT_7506
AAFAURANDRAFT_22965
PIFPITG_17942
PSOJPHYSODRAFT_348923
SPARSPRG_11296
EHXEMIHUDRAFT_425916 EMIHUDRAFT_428127
GTTGUITHDRAFT_111018
TBRTb09.160.3210
TBGTbgDal_IX2440
TCR511585.130
NGRNAEGRDRAFT_82821
TVATVAG_2v0228020 TVAG_2v0330060
GLAGL50803_004083
CSUCSUB_C1476
LOKILokiarch_29320(moeB_2)
 » show all
Reference
1  [PMID:9694792]
  Authors
Osaka F, Kawasaki H, Aida N, Saeki M, Chiba T, Kawashima S, Tanaka K, Kato S
  Title
A new NEDD8-ligating system for cullin-4A.
  Journal
Genes Dev 12:2263-8 (1998)
DOI:10.1101/gad.12.15.2263
  Sequence
[hsa:9039]
Reference
2  [PMID:10207026]
  Authors
Gong L, Yeh ET
  Title
Identification of the activating and conjugating enzymes of the NEDD8 conjugation pathway.
  Journal
J Biol Chem 274:12036-42 (1999)
DOI:10.1074/jbc.274.17.12036
  Sequence
[hsa:9039]
Other DBs
ExplorEnz - The Enzyme Database: 6.2.1.64
IUBMB Enzyme Nomenclature: 6.2.1.64
ExPASy - ENZYME nomenclature database: 6.2.1.64
BRENDA, the Enzyme Database: 6.2.1.64

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