KEGG   ENZYME: 7.2.2.19
Entry
EC 7.2.2.19                 Enzyme                                 
Name
H+/K+-exchanging ATPase;
H+-K+-ATPase;
H,K-ATPase;
(K+ + H+)-ATPase
Class
Translocases;
Catalysing the translocation of inorganic cations;
Linked to the hydrolysis of a nucleoside triphosphate
Sysname
ATP phosphohydrolase (P-type,H+/K+-exchanging)
Reaction(IUBMB)
ATP + H2O + H+[side 1] + K+[side 2] = ADP + phosphate + H+[side 2] + K+[side 1]
Substrate
ATP [CPD:C00002];
H2O [CPD:C00001];
H+[side 1];
K+[side 2]
Product
ADP [CPD:C00008];
phosphate [CPD:C00009];
H+[side 2];
K+[side 1]
Comment
A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A gastric mucosal enzyme that catalyses the efflux of one H+ and the influx of one K+ per ATP hydrolysed.
History
EC 7.2.2.19 created 1984 as EC 3.6.1.36, transferred 2000 to EC 3.6.3.10, transferred 2018 to EC 7.2.2.19
Pathway
ec00190  Oxidative phosphorylation
ec01100  Metabolic pathways
Orthology
K01542  H+/K+-exchanging ATPase subunit alpha
K01543  H+/K+-exchanging ATPase subunit beta
K01544  non-gastric H+/K+-exchanging ATPase
Genes
HSA: 479(ATP12A) 495(ATP4A) 496(ATP4B)
PTR: 738405(ATP4B) 747915(ATP4A)
PPS: 100979788(ATP12A) 100980523(ATP4A) 100991047(ATP4B)
GGO: 101138827(ATP4A) 101141471(ATP4B) 101142592(ATP12A)
PON: 100435235(ATP4A) 100435325(ATP12A) 100459814(ATP4B) 129047301
PPYG: 129011227(ATP12A) 129011828(ATP4B) 129020752(ATP4A)
NLE: 100582869(ATP12A) 100593416(ATP4A) 100603851(ATP4B)
HMH: 116466399(ATP12A) 116467592(ATP4B) 116478910(ATP4A)
SSYN: 129461144(ATP4A) 129463622(ATP12A) 129463890(ATP4B)
MCC: 100426215(ATP4A) 698222(ATP4B) 721488(ATP12A)
MCF: 102119167(ATP12A) 102124568(ATP4A) 102131451(ATP4B)
MTHB: 126940838 126940867 126941882
MNI: 105485243(ATP4B) 105490245(ATP12A) 105495516(ATP4A)
CSAB: 103214853(ATP4B) 103234521(ATP4A) 103249015(ATP12A)
CATY: 105578179(ATP4A) 105584959(ATP4B) 105591901
PANU: 100998598(ATP4B) 101008375(ATP4A) 101018431
TGE: 112610847(ATP12A) 112610870(ATP4B) 112613167(ATP4A)
MLEU: 105539236(ATP4B) 105541294(ATP4A) 105553824(ATP12A)
RRO: 104659972(ATP12A) 104667094(ATP4A) 104671368(ATP4B)
RBB: 108512346(ATP4A) 108515377(ATP12A) 108521834(ATP4B)
TFN: 117063465(ATP4B) 117092362(ATP4A) 117098305(ATP12A)
PTEH: 111525000(ATP12A) 111529928(ATP4A) 111546384(ATP4B)
CANG: 105505933(ATP4B) 105516102(ATP4A) 105523740(ATP12A)
CJC: 100400287(ATP12A) 100405348(ATP4A) 100414695(ATP4B)
SBQ: 101047397(ATP12A) 101047734(ATP4A) 101051285(ATP4B)
CIMI: 108286357(ATP4A) 108293398(ATP12A) 108297110(ATP4B)
ANAN: 105704902(ATP12A) 105707158(ATP4A) 105729756(ATP4B)
CSYR: 103254666 103268157(ATP12A) 103271326(ATP4B) 103273562(ATP4A)
MMUR: 105871943(ATP4B) 105876924(ATP4A) 105878841(ATP12A)
LCAT: 123624471(ATP4A) 123648826(ATP4B) 123649506(ATP12A)
PCOQ: 105808129(ATP12A) 105816253(ATP4A) 105825135(ATP4B)
OGA: 100940453(ATP4B) 100941378(ATP4A) 100958415(ATP12A)
MMU: 11944(Atp4a) 11945(Atp4b) 192113(Atp12a)
MCAL: 110297674(Atp4a) 110300103(Atp4b) 110309153(Atp12a)
MPAH: 110316696(Atp4a) 110325315(Atp12a) 110336832(Atp4b)
RNO: 171028(Atp12a) 24216(Atp4a) 24217(Atp4b)
MCOC: 116071161(Atp4b) 116085109(Atp12a) 116101990(Atp4a)
ANU: 117705446(Atp12a) 117712562(Atp4a) 117721865(Atp4b)
ASYL: 127668582(Atp4b) 127682822(Atp4a) 127690940(Atp12a)
MUN: 110551638(Atp4a) 110558241(Atp4b) 110559568(Atp12a)
CGE: 100750430(Atp4b) 100765522(Atp12a) 100767384(Atp4a)
MAUA: 101834043(Atp4a) 101840044(Atp4b) 101844033(Atp12a)
PROB: 127220278(Atp4b) 127230349(Atp12a) 127238907(Atp4a)
PLEU: 114681649(Atp4a) 114683800(Atp12a) 114701215(Atp4b)
MORG: 121434991(Atp12a) 121449422(Atp4a) 121462110(Atp4b)
MFOT: 126486695 126492615 126498731
AAMP: 119800127(Atp12a) 119813512(Atp4b) 119821880(Atp4a)
NGI: 103726773(Atp12a) 103729925(Atp4a) 103746296(Atp4b)
HGL: 101697924(Atp4b) 101711071(Atp12a) 101724247(Atp4a)
CPOC: 100135482(Atp12a) 100731685(Atp4b) 100732743(Atp4a)
CCAN: 109674869(Atp12a) 109686917(Atp4b) 109689140(Atp4a)
DORD: 105990414(Atp4b) 105992620(Atp12a) 105993074(Atp4a)
DSP: 122097466(Atp4a) 122112681(Atp12a) 122122856(Atp4b)
PLOP: 125347908(Atp12a) 125348089(Atp4b) 125368255(Atp4a)
NCAR: 124966338 124984830 124985869
MMMA: 107140877(Atp4b) 107151750(Atp4a) 107153774(Atp12a)
ITI: 101959865(Atp4b) 101963004(Atp12a) 101964579(Atp4a)
OCU: 100008669(ATP12A) 100009125(ATP4B) 100009279(ATP4A)
OPI: 101519902(ATP12A) 101526616(ATP4B) 101532969(ATP4A)
TUP: 102472050(ATP4B) 102475043(ATP12A) 102480463(ATP4A)
GVR: 103590632(ATP4B) 103601451(ATP4A) 103607310(ATP12A)
CFA: 403820(ATP12A) 404020(ATP4B) 431686(ATP4A)
CLUD: 112643525(ATP4A) 112656012(ATP4B) 112669581(ATP12A)
VVP: 112918512(ATP12A) 112927436(ATP4B) 112928326(ATP4A)
VLG: 121477139(ATP4B) 121479246(ATP4A) 121497686(ATP12A)
NPO: 129500580(ATP4A) 129504604(ATP12A) 129516344(ATP4B)
AML: 100465081(ATP4A) 100465461(ATP12A) 100477747(ATP4B)
UMR: 103657517(ATP4B) 103664389(ATP12A) 103682508(ATP4A)
UAH: 113244763(ATP4A) 113247563(ATP4B) 125281802(ATP12A)
UAR: 123776756(ATP4B) 123792000(ATP12A) 123793887(ATP4A)
ELK: 111147139 111159902 111161471
LLV: 125088370 125094869 125096136
MPUF: 101689957(ATP4B) 101692909(ATP12A) 106003277(ATP4A)
MNP: 132002590(ATP12A) 132002613(ATP4B) 132006068(ATP4A)
MLK: 131813511(ATP4B) 131813966(ATP12A) 131818496(ATP4A)
NVS: 122906890(ATP12A) 122907905(ATP4B) 122911556(ATP4A)
ORO: 101367449(ATP12A) 101368519(ATP4A) 101369365(ATP4B)
EJU: 114196614(ATP4B) 114204018 114210997(ATP12A) 114224363(ATP4A)
ZCA: 113920154(ATP4B) 113920413(ATP12A) 113935424(ATP4A)
MLX: 118009110(ATP4B) 118022790(ATP4A) 118026855
NSU: 110570195(ATP12A) 110585884(ATP4B) 110590090(ATP4A)
LWW: 102728557(ATP4A) 102732485(ATP4B) 102734201(ATP12A)
FCA: 101091583(ATP12A) 101092078(ATP4B) 101100771(ATP4A)
PYU: 121022550(ATP12A) 121037674(ATP4B)
PCOO: 112851271(ATP4A) 112860876(ATP12A) 112861357(ATP4B)
PBG: 122480267(ATP12A) 122485157(ATP4B) 122495067(ATP4A)
PVIV: 125153523(ATP4A) 125165428(ATP4B) 125176379(ATP12A)
LRUF: 124502271 124511813 124514002
LGF: 123578213(ATP4A) 123584830(ATP12A) 123600591(ATP4B)
AJU: 106974749 106979787 106986712
PTG: 102957326(ATP12A) 102964110(ATP4A) 102971257(ATP4B)
PPAD: 109251505(ATP4A) 109259125(ATP12A) 109264027(ATP4B)
PUC: 125915911 125933638 125933984
PLEZ: 122207215(ATP12A) 122208198(ATP4A) 122229480(ATP4B)
HHV: 120223456(ATP4B) 120243462(ATP4A) 120248570(ATP12A)
BTA: 521163(ATP4A) 530703(ATP12A) 614308(ATP4B)
BOM: 102273487(ATP4A) 102275089(ATP12A) 102276541(ATP4B)
BIU: 109567033(ATP4B) 109567056(ATP12A) 109571697(ATP4A)
BBUB: 102404508(ATP4B) 102412846(ATP12A) 102415959(ATP4A)
BBIS: 104982120(ATP4B) 104982884(ATP12A) 104995244(ATP4A)
CHX: 102172639(ATP12A) 102180792(ATP4A) 102185581(ATP4B)
OAS: 101116166(ATP4A) 101120253(ATP12A) 114116709(ATP4B)
BTAX: 128057503(ATP12A) 128057850(ATP4B) 128062999(ATP4A)
CSUM: 138089029(ATP12A) 138089359(ATP4B) 138095764(ATP4A)
ODA: 120873301(ATP4A) 120883224(ATP12A) 120883388(ATP4B)
CCAD: 122421382(ATP4A) 122447536(ATP12A) 122447558(ATP4B)
MREE: 136144082(ATP12A) 136144177(ATP4B) 136161184(ATP4A)
OVR: 110123675(ATP4A) 110141673(ATP4B) 110151814(ATP12A)
MBEZ: 129546062(ATP4A) 129556557(ATP12A) 129556651(ATP4B)
SSC: 100521921(ATP12A) 397131(ATP4B) 397552(ATP4A)
CFR: 102505116(ATP4A) 102505590(ATP12A) 102520241(ATP4B)
CBAI: 105065041(ATP4A) 105066291(ATP12A) 105066876(ATP4B)
CDK: 105088096(ATP4A) 105091347(ATP4B) 105096383(ATP12A)
VPC: 102526679(ATP4B) 102530856(ATP4A)
BACU: 103000639(ATP4B) 103012701(ATP4A) 103013174(ATP12A)
BMUS: 118883940(ATP12A) 118884392(ATP4B) 118884801(ATP4A)
LVE: 103071695(ATP4B) 103071724(ATP4A) 103091328(ATP12A)
OOR: 101270907(ATP12A) 101275692(ATP4B) 101276734(ATP4A)
LALB: 132508929(ATP4B) 132508982(ATP12A) 132509544(ATP4A)
DLE: 111175101 111176321(ATP4B) 111181140(ATP4A)
PCAD: 102992690(ATP4B) 102994540(ATP12A) 102994597(ATP4A)
PSIU: 116743261(ATP4B) 116743292(ATP12A) 116744556(ATP4A)
NASI: 112392228(ATP4A) 112403659(ATP12A) 112404624(ATP4B)
ECB: 100052912(ATP12A) 100069135(ATP4B) 100147108(ATP4A)
EPZ: 103540402(ATP12A) 103549650(ATP4B) 103560041(ATP4A)
EAI: 106827635(ATP12A) 106829240(ATP4A) 106848204(ATP4B)
MYB: 102246595(ATP12A) 102249396(ATP4A) 102259435(ATP4B)
MYD: 102753224(ATP4A) 102760948(ATP4B) 102774686(ATP12A)
MMYO: 118651209(ATP12A) 118659640(ATP4B) 118674738(ATP4A)
MLF: 102427161(ATP4A) 102430275(ATP12A) 102433406(ATP4B)
MDT: 132216993(ATP4A) 132225861(ATP12A) 132228571(ATP4B)
MYUM: 138996781(ATP4A) 139004920(ATP4B) 139006748(ATP12A)
PKL: 118720628(ATP4A) 118728745(ATP12A) 118729705(ATP4B)
EFUS: 103284507(ATP4A) 103288299(ATP4B) 103301258(ATP12A)
MNA: 107529938(ATP12A) 107536947(ATP4B) 107543398(ATP4A)
DRO: 112320122(ATP4A) 112321536(ATP4B) 112323160(ATP12A)
SHON: 118980541(ATP12A) 118982540(ATP4A) 118984262(ATP4B)
AJM: 119034612(ATP4B) 119041295(ATP12A) 119044216(ATP4A)
PDIC: 114508905(ATP4B) 114511655(ATP4A) 114514025(ATP12A)
PHAS: 123807486(ATP4B) 123822694(ATP12A) 123823744(ATP4A)
MMF: 118622394(ATP4B) 118624296(ATP12A) 118638589(ATP4A)
PPAM: 129064670(ATP4B) 129073808(ATP12A) 129083092(ATP4A)
HAI: 109372015(ATP4A) 109383950(ATP4B) 109387998(ATP12A)
RFQ: 117021725(ATP4B) 117021768(ATP12A) 117035341(ATP4A)
PALE: 102881469(ATP12A) 102881537(ATP4B) 102882245(ATP4A)
PGIG: 120592418(ATP4A) 120610690(ATP12A) 120615612(ATP4B)
PVP: 105305088(ATP4B) 105306638(ATP4A)
RAY: 107497657(ATP4A) 107502956(ATP12A) 107514348(ATP4B)
MJV: 108394994(ATP12A) 108398957(ATP4A) 108399961(ATP4B)
TOD: 119248621(ATP4A) 119258939(ATP12A) 119259642(ATP4B)
SARA: 101545017(ATP4B) 101550748(ATP12A) 101559007(ATP4A)
SFUM: 130037417(ATP4B) 130043943(ATP4A)
SETR: 126016026(ATP4B) 126020178(ATP12A) 126028489(ATP4A)
LAV: 100657258 100657835 100663989(ATP4B) 100670470(ATP4A)
TMU: 101348997 101350003 101351027 101351289 101351555
ETF: 101645840(ATP4B) 101656652(ATP4A) 101662203 101663158 101664088
DNM: 101419560(ATP4B) 101422745(ATP12A) 101442103(ATP4A)
MDO: 100013166(ATP4A) 100016220(ATP4B) 100022970(ATP12A) 100022999 100023029
GAS: 123238898 123238900 123238901 123239805(ATP4B) 123243026(ATP4A)
SHR: 100914456 100914716 100914816(ATP4B) 100926385(ATP4A)
AFZ: 127553498 127554776 127554777 127556065
PCW: 110193383(ATP4B) 110195855 110195856 110195881 110195885 110201386(ATP4A)
TVP: 118837887 118837895 118837896 118839023(ATP4A) 118845299(ATP4B)
PBRV: 138155272 138155528 138155551 138165753(ATP4B)
OAA: 100092554 107547886(ATP4B)
TACU: 119934175(ATP12A) 119941264(ATP4B)
GGA: 386581(ATP4B) 419743(ATP12A)
PCOC: 116233002(ATP12A) 116242796(ATP4B)
MGP: 100548075(ATP4B) 100550873(ATP12A)
CJO: 107307398 107307930(ATP4B) 107324177(ATP12A)
TPAI: 128087487(ATP12A) 128092157(ATP4B)
LMUT: 125700824(ATP4B) 125703758(ATP12A)
NMEL: 110387724(ATP12A) 110407217(ATP4B)
APLA: 101793299(ATP4B) 101800708(ATP12A) 119714257(ATP4A)
ACYG: 106040569(ATP12A) 106046430(ATP4B)
CATA: 118252378(ATP12A) 118257500(ATP4B) 118261601 118261629(ATP4A)
AFUL: 116497802(ATP12A) 116501745(ATP4A) 116502387(ATP4B)
TGU: 100230086(ATP12A) 100230444(ATP4B) 115492958(ATP4A)
LSR: 110468196(ATP12A) 110478747(ATP4B) 110483038
SCAN: 103812391(ATP4B) 103823636(ATP12A)
PMOA: 120504701(ATP4B) 120508470(ATP12A) 120510986
OTC: 121340772(ATP12A) 121343216(ATP4B)
PRUF: 121352629(ATP4B) 121360596(ATP12A)
ATRC: 139586089 139591721(ATP4B) 139600891
GFR: 102031709(ATP4B) 102044487(ATP12A)
FAB: 101805703(ATP4B) 101807408(ATP12A)
OMA: 130248576(ATP4B) 130262431(ATP12A) 130263330
PHI: 102099301(ATP4A) 102107731(ATP12A) 102110942(ATP4B)
PMAJ: 107200428(ATP4B) 107214473(ATP12A)
CCAE: 111922763(ATP4B) 111939335(ATP12A)
CCW: 104686103(ATP4B) 104692117(ATP12A)
CBRC: 103617551(ATP4B) 103618483(ATP12A)
ACOE: 138098284(ATP12A) 138101612 138118111(ATP4B)
ETL: 114057871(ATP4B) 114059527(ATP12A)
ZAB: 102067076(ATP4B) 102071800(ATP12A)
ZLE: 135447034(ATP4B) 135457397(ATP12A) 135461007(ATP4A)
ACHL: 103797643(ATP4B) 103800232(ATP12A)
SVG: 106857469(ATP12A) 106858435(ATP4B) 106864376(ATP4A)
MMEA: 130585432(ATP12A) 130586198(ATP4B)
HRT: 120749332(ATP4B) 120762521(ATP12A)
SATI: 136371084 136375176(ATP4B)
CCIC: 134053686(ATP12A) 134055861(ATP4A) 134058022(ATP4B)
FPG: 101911437(ATP4A) 101912680(ATP12A) 101923846(ATP4B)
FCH: 102051647(ATP4B) 102055866(ATP4A) 102056385(ATP12A)
CCRI: 104154888(ATP4B) 104161098(ATP12A)
NNT: 104401099(ATP4B) 104403833(ATP12A)
SHAB: 115602672(ATP4B) 115616274(ATP12A)
ACUN: 113483761(ATP4B) 113488438
TALA: 104367185(ATP12A) 104368768(ATP4B)
ACHC: 115334614(ATP4B) 115345206(ATP12A)
HALD: 104314953(ATP4B) 104318330(ATP12A)
HLE: 104836597 104836891(ATP4B) 104840466(ATP12A)
AGEN: 126035147 126038380 126052848
HHAR: 128135330(ATP4B) 128138419 128141563(ATP12A)
GCL: 127025766 127029482
CSTI: 104562132(ATP12A) 104563826(ATP4B)
LDI: 104344343(ATP12A)
MNB: 103770271(ATP12A) 103775206(ATP4B)
DPUB: 104298633(ATP4B) 104301005(ATP12A)
PPUS: 135175699(ATP4B) 135191110(ATP12A)
AVIT: 104267173(ATP4B) 104278430(ATP12A)
BRHI: 104490829(ATP4B) 104499986(ATP12A)
EGZ: 104126355(ATP4B) 104129213(ATP12A)
NNI: 104011769 104016631(ATP12A) 104019363(ATP4B)
PCRI: 104025066(ATP4B) 104038866(ATP12A)
PCAO: 104047644(ATP12A) 104049714(ATP4B)
PADL: 103918852(ATP4B) 103924807(ATP12A)
AFOR: 103896267(ATP4B) 103900590(ATP12A) 103901363
FGA: 104075212(ATP4B) 104082600(ATP12A)
GSTE: 104254118(ATP12A) 104260403(ATP4B)
CLV: 102093855(ATP4B) 102096447(ATP12A)
MUI: 104541132(ATP4B) 104546756(ATP12A)
PGUU: 104457839(ATP4B) 104461546(ATP12A)
PLET: 104619478(ATP12A) 104620876(ATP4B)
EHS: 104502662(ATP4B) 104508395(ATP12A)
CMAC: 104477570(ATP12A) 104487016(ATP4B)
CUCA: 104056296(ATP12A) 104056622(ATP4B) 128849903(ATP4A)
TEO: 104373628(ATP12A) 104375187(ATP4B)
BREG: 104637889(ATP4B) 104638598(ATP12A)
OHA: 104331863(ATP4B) 104336398(ATP12A)
ACAR: 104525867(ATP4B) 104531729(ATP12A)
CPEA: 104388968(ATP4B) 104393392(ATP12A)
CVF: 104291541(ATP12A) 104292711(ATP4B) 104294498
RTD: 128903884(ATP4A) 128917378(ATP4B) 128918523(ATP12A)
AAM: 106490229(ATP12A) 106493946(ATP4B)
AROW: 112960870(ATP4B) 112963221 112968934(ATP12A)
NPD: 112946322(ATP12A) 112953183(ATP4B) 112957892(ATP4A)
TGT: 104567366(ATP4B) 104575248(ATP12A)
DNE: 112981390(ATP4B) 112982673(ATP12A) 112996443
SCAM: 104138053(ATP4B) 104143518(ATP12A)
ASN: 102374285(ATP4B) 102387741(ATP4A) 102388005(ATP12A)
AMJ: 102561484(ATP12A) 102575926(ATP4B) 109283416
CPOO: 109306290(ATP4B) 109318032(ATP12A)
GGN: 109292371(ATP12A) 109303472(ATP4B)
PSS: 102450978(ATP4A) 102452724(ATP12A) 102457968(ATP4B)
CMY: 102933065(ATP12A) 102936245(ATP4A) 102942318(ATP4B)
CCAY: 125625445(ATP12A) 125625842(ATP4A) 125628790(ATP4B)
DCC: 119846638(ATP12A) 119847678(ATP4A) 119848060(ATP4B)
CPIC: 101946000(ATP4A) 101947527(ATP12A) 101951389(ATP4B)
TST: 117868663(ATP12A) 117869762(ATP4A) 117870769(ATP4B)
CABI: 116823339(ATP4B) 116833676(ATP4A) 116837728(ATP12A)
MRV: 120375453(ATP12A) 120390272(ATP4A) 120395477(ATP4B)
ACS: 100560046(atp4b) 100563430 100563553(atp4a)
ASAO: 132770217(ATP4B) 132780244(ATP4A) 132782599(ATP12A)
PVT: 110074103(ATP4B) 110079317(ATP12A) 110089078(ATP4A)
SUND: 121915588(ATP4A) 121927015(ATP4B) 121933066(ATP12A)
PBI: 103053937(ATP12A) 103054731(ATP4A) 103064507
PMUR: 107286485(ATP12A) 107290450(ATP4B) 107292625(ATP4A)
CTIG: 120300069(ATP4A) 120310589(ATP4B) 120319550(ATP12A)
TSR: 106539185(ATP4B) 106548299 106552003
PGUT: 117666518(ATP4B) 117668233(ATP12A) 117669240(ATP4A)
APRI: 131199966(ATP4B) 131203886(ATP12A) 131204521(ATP4A)
PTEX: 113440818(ATP4B) 113441844(ATP12A) 113448214(ATP4A)
NSS: 113411601(ATP4B) 113419303(ATP12A) 113423747(ATP4A)
VKO: 123019395(ATP4A) 123022672(ATP4B) 123028028(ATP12A)
PMUA: 114585731(ATP12A) 114596444(ATP4B) 114602396(ATP4A)
PRAF: 128402400(ATP12A) 128411855(ATP4B) 128418525(ATP4A)
ZVI: 118084839(ATP4B) 118087382(ATP4A) 118096947(ATP12A)
HCG: 128332837(ATP4A) 128333746(ATP12A) 128352271(ATP4B)
GJA: 107110926(ATP4B) 107116203(ATP4A) 107120678(ATP12A)
STOW: 125431344(ATP4B) 125434809(ATP4A) 125441940(ATP12A)
EMC: 129326724(ATP4B) 129341986(ATP12A) 129343052(ATP4A)
XLA: 108696872 108716413 379283(atp12a.L) 379459(atp4b.S) 380512(atp12a.S) 447127(atp4b.L) 733327(atp4a.S)
XTR: 100488221(atp4a) 448282(atp4b) 594945(atp12a-like)
NPR: 108790589(ATP12A) 108790966 108790973 108791690(ATP4B) 108797188(ATP4A)
RTEM: 120915674(ATP12A) 120916253(ATP4A) 120916471 120926395(ATP4B)
BBUF: 120986820(ATP4A) 120993481(ATP4B) 121000065(ATP12A) 121002743
BGAR: 122926670 122928793(ATP12A) 122933327(ATP4B)
PWL: 138246521(ATP4A) 138246687 138249542(ATP4B) 138285017(ATP12A)
MUO: 115469147(ATP4B) 115476325(ATP4A) 115481773(ATP12A) 115482125
GSH: 117345556(ATP4A) 117347037(ATP12A) 117362829(ATP4B)
TROS: 130553427 130558516
TDW: 130413759 130432786
IPU: 108256310 108259063
IFU: 128599446 128601707
PHYP: 113532853(atp4a) 113537621(atp4b)
SMEO: 124375394 124378676
TFD: 113648878 113649694
TVC: 132839271 132840464
CGAR: 128506476 128514132
NGRA: 132865756 132867492
TRN: 134300983 134329420
AMEX: 103023943 103024000
CMAO: 118798088 118798703
EEE: 113571928(atp4a) 113577520(atp4b)
CHAR: 105891898 105896508
SPIL: 134071686 134082744
LCO: 104919947(atp4b) 104940311(atp4a)
NCC: 104957693(atp4a) 104958804(atp4b)
TBEN: 117471901 117480677
CGOB: 115006065(atp4b) 115021320(atp4a)
PGEO: 117460896 117460994
GACU: 117548276 117553940
EMAC: 134861591 134863525
ELY: 117260771 117265754
EFO: 125892646 125903207
PLEP: 121942309 121946001
SLUC: 116049457 116067660
ECRA: 117946445 117949401
ESP: 116691811 116699051(atp4b)
PFLV: 114556886(atp4a) 114561383(atp4b)
GAT: 120809652 120810035
PPUG: 119197524 119229020
AFB: 129108505 129109106
CLUM: 117745041 117749848
PSWI: 130192268 130212544
CANA: 137781313 137785057
CVE: 137887545 137891473
MSAM: 119897685 119908241
SCHU: 122878896 122881314
ALAT: 119005673 119017714
ASTR: 137601982 137605691
MZE: 101464178(atp4a) 101482966(atp4b) 112434842
ONL: 100690043(atp4a) 100698050(atp4b)
OAU: 116312210 116331347
AOCE: 111565500(atp4b) 111573133(atp4a)
MCEP: 125005523 125016364
POV: 109624948(atp4b) 109633020(atp4a)
SSEN: 122772736 122774091
HHIP: 117757682 117776339
HSP: 118114115 118125016
PPLT: 128440120 128449648
SMAU: 118290733 118302858
LCF: 108888014 108892214
SDU: 111236799(atp4a) 111238420(atp4b)
SLAL: 111652775(atp4a) 111668322(atp4b)
XGL: 120784338 120795460
BPEC: 110171389(atp4a) 110173092(atp4b)
MALB: 109964254(atp4b) 109967366(atp4a)
BSPL: 114842534 114852357
SJO: 128360625 128366014
SSCO: 133984084 133984554
GMH: 115553894(atp4a) 115559074(atp4b)
SASA: 106574844 106577750 106594464(atp4b) 106605632
STRU: 115176661 115179540(atp4b) 115179541 115182575
OTW: 112227190 112242012 112245864
OMY: 100136301 110519329 110519929 118936670
OGO: 123997984 124005106 124024975
ONE: 115102130 115140890
OKI: 109886265 109887138 109900952 109901664
OKE: 118364085 118367644 118379637
OMM: 135520459 135522034 135536456 135536461
SALP: 111959186 111964878 112077546(atp4b)
SNH: 120031708 120039469 120039484 120048543
CCLU: 121543053 121556072 121556764 123485649
ELS: 105019136(atp4a) 105020060(atp4b)
SFM: 108919133(atp4a) 108931953(atp4b)
PKI: 111841121(atp4a) 111845443
AANG: 118211254 118223461
AROT: 135237877 135251863
CCOG: 133123688 133127017
LOC: 102687313(atp4a) 102692102(atp4b)
PSPA: 121299114 121320884 121327874
ARUT: 117406220 117407214 117434009 117968514
PSEX: 120517152 120524415 120535954 120541731
LCM: 102352096(ATP4A) 102355665(ATP4B)
RTP: 109913661
CPLA: 122540695 122555528
HOC: 132820669 132829488
LERI: 129702475 129712394
PMRN: 116955251
LRJ: 133347765
SSAO: 94294628(SS50377_20605)
 » show all
Reference
1  [PMID:5682852]
  Authors
Sachs G, Collier RH, Shoemaker RL, Hirschowitz BI.
  Title
The energy source for gastric H+ secretion.
  Journal
Biochim Biophys Acta 162:210-9 (1968)
DOI:10.1016/0005-2728(68)90103-5
Reference
2  [PMID:2552824]
  Authors
Hersey SJ, Perez A, Matheravidathu S, Sachs G.
  Title
Gastric H+-K+-ATPase in situ: evidence for compartmentalization.
  Journal
Am J Physiol 257:G539-47 (1989)
DOI:10.1152/ajpgi.1989.257.4.G539
Reference
3  [PMID:2158765]
  Authors
Rabon EC, Reuben MA.
  Title
The mechanism and structure of the gastric H,K-ATPase.
  Journal
Annu Rev Physiol 52:321-44 (1990)
DOI:10.1146/annurev.ph.52.030190.001541
Other DBs
ExplorEnz - The Enzyme Database: 7.2.2.19
IUBMB Enzyme Nomenclature: 7.2.2.19
ExPASy - ENZYME nomenclature database: 7.2.2.19
BRENDA, the Enzyme Database: 7.2.2.19

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