KEGG   Equus caballus (horse): 100070891
Entry
100070891         CDS       T01058                                 
Name
(RefSeq) ALK tyrosine kinase receptor
  KO
K05119  anaplastic lymphoma kinase [EC:2.7.10.1]
Organism
ecb  Equus caballus (horse)
Pathway
ecb05200  Pathways in cancer
ecb05223  Non-small cell lung cancer
ecb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:ecb00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100070891
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    100070891
  09162 Cancer: specific types
   05223 Non-small cell lung cancer
    100070891
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ecb01001]
    100070891
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:ecb04090]
    100070891
Enzymes [BR:ecb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100070891
Protein kinases [BR:ecb01001]
 Receptor tyrosine kinases (RTK)
  ALK family
   100070891
CD molecules [BR:ecb04090]
 Proteins
  100070891
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Gly_rich MAM FXa_inhibition
Other DBs
NCBI-GeneID: 100070891
NCBI-ProteinID: XP_023474203
Position
15:68270948..68370768
AA seq 1009 aa
MSWLIRGVLQGNVSLVLVENKTGKEQSRMVWHVATNEGLSLWQWTVLPLLDVADRFWLQI
VAWWGQGSRATVAFDNISISLDCYLTISGEDKMPQNTAPKSRNLFERNSNKESKPWENTP
GETPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYRNSNLSVVVGSEGPLKGIQTWKVPAT
DTYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDMLYILVGQQGEDACPSTNRLIQ
KVCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGVPVPLIIAAGGGGRAYGA
KTDTFHPERLENNSSVLGLNGNSGAAVWFATGGNAASDNDPEMDGEDGVSFISPLGILYT
PALKVMEGHGEVNIKHYLNCSHCEVDECHMDPESHKIICFCDHGTVLAEDGVSCIVSPTP
EPHLPLSLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTST
IMTDYNPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQV
AVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGGDLKSF
LRETRPRPNQPSSLAMLDLLHVAQDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAK
IGDFGMARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGY
MPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCT
QDPDVINTALPIEYGPLVEEEEKVPMRPKDPEGMPPLLVSPPQAKREEGQGPAAPLPLPS
TSSSKAMKKPTAAEISVRVTRAPAVEGGHVNMAFSQSNPPSELHKVQGSRNKPTSLWNPT
YGSWFTEKPAKKNNPPAKMEQQERGNLGREGSCTVPPNMAAGRLPGASLLLEPSSLTANM
KEVPLFRLRHFPCGNVNYGYQQQGLPLEATPAPGTSHYEDAILKTQPGP
NT seq 3030 nt   +upstreamnt  +downstreamnt
atgtcctggctcatccgtggagtcttgcagggaaacgtctccttggtgctggtggaaaac
aaaactgggaaggagcaaagcaggatggtctggcatgtggccaccaatgaaggcttgagc
ctgtggcagtggacggtgctacctctcctggatgtggccgacaggttctggctgcagatt
gtcgcttggtggggacaaggatccagagccaccgtggcttttgacaatatctccatcagc
ctggactgctacctcaccatcagtggggaggacaagatgccacagaatacagcacccaaa
tcaagaaatctgtttgaaagaaattcaaacaaggagtcgaaaccctgggaaaatacacca
ggagagacccccatctttgaccctacagttcactggctcttcaccacgtgcggggccagc
gggccccatggccccacgcaggcccagtgcaacaacgcctaccggaactccaacctgagc
gtggtggtggggagcgagggccccctgaagggcatccagacctggaaggtgccagccacc
gacacctacagcatctcgggctatggagctgctggcgggaaaggcgggaagaacaccatg
atgcggtcccacggcgtgtctgtgctgggcatcttcaacctggagaaggacgacatgctg
tacatcctggtcgggcaacagggggaagacgcctgccccagcacaaaccgattaatccag
aaagtctgcattggagagaacaacgtgatagaagaagaaatccgcgtgaacagaagcgtg
catgagtgggcaggaggcggcggaggaggaggcggagccacctacgtgtttaagatgaag
gatggcgtgcccgtgcccctgatcattgcagccggcggtggcggccgggcctacggggcc
aagacagacacattccacccagagagactggagaataactcctcggttctggggctcaac
ggcaattccggagccgcagtctggtttgccacaggcggcaacgcagcctcagacaatgac
cccgagatggacggagaggatggggtctccttcatcagtccactgggcatcctgtacacc
ccggctttaaaagtgatggagggccacggggaagtaaatattaagcattacctaaactgc
agccactgtgaggtagatgagtgccacatggaccccgagagccacaagatcatctgcttc
tgtgaccatgggacagtgctggcagaggatggcgtctcctgcatcgtctcacccaccccg
gagccccacctgccactctcgctgatcctctctgtcgtgacctctgccctcgtggccgcc
ctcgtcctggctttctctggcatcatgatcgtgtaccgccggaagcaccaggagctgcaa
gccatgcagatggagctgcagagtcccgagtacaagctgagcaagctccgcacttcaacc
atcatgaccgactacaaccccaactactgctttgctggcaagacctcctccatcagtgac
ctgaaggaggtgccgcggaaaaacatcaccctcattcggggtctgggccatggcgcattt
ggggaggtgtatgaaggccaggtgtctggaatgcccaacgacccaagccccctgcaagtg
gctgtaaagacgctgcctgaggtatgttccgaacaggatgaactggatttcctcatggaa
gccctgatcatcagcaaattcaaccaccagaacatcgtgcgctgtattggggtgagtctg
caagccttgccccggtttatcctgctggagctcatggcgggaggagacctcaagtccttc
ctccgggagacccgccctcgcccgaatcagccctcctccctggccatgctggaccttctg
catgtggctcaggacatcgcctgtggttgtcagtatctagaggaaaatcacttcatccac
cgggacattgctgccagaaactgcctcctgacctgtccaggccctggaagagtggccaag
attggggactttggaatggcccgagacatctacagagcaagctactaccgaaagggaggc
tgtgcaatgctgccagtcaaatggatgcccccagaggccttcatggaaggaatatttact
tctaaaacagacacgtggtccttcggagtgctgctgtgggaaatattttctctcggatat
atgccgtaccctagcaaaagcaaccaggaagttctggagttcgtcaccagcggaggacgg
atggacccacctaagaactgccctgggcctgtataccggataatgacccagtgctggcaa
caccagcctgaagacaggcccaactttgccataattttggagaggattgaatactgcacc
caggacccagatgtgatcaacacagctttgccaatagaatatggcccactcgtggaggag
gaagagaaagtgcctatgaggcccaaagaccccgagggaatgcctcctctgctagtctct
cctccccaagctaaacgtgaggaaggacagggtccagctgccccgctccctctgccttcc
acttcgtctagcaaagccatgaagaaaccaacagctgcagagatctctgttcgagtcact
agagcgccagccgtggaagggggacatgttaatatggcattctctcagtccaacccacca
tcagagctgcacaaagtccagggatccagaaacaaaccaaccagcctatggaatccaact
tatggctcatggtttacagagaaacccgccaaaaagaacaatcctccagcaaagatggag
caacaggagaggggaaacttgggacgtgagggaagctgtactgtcccccctaacatggca
gctggcagacttccaggcgcctctctgctcctagaaccatcttcgctgactgccaacatg
aaggaagttcccctgtttaggctgcgtcacttcccgtgtggaaatgtcaactatggctac
cagcaacagggcttacctttagaggccacccctgcccctggaactagtcattatgaggac
gccattctgaaaacccagcctgggccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (31)   

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