KEGG   Escherichia coli O83 H1 NRG 857C (AIEC): NRG857_00440
Entry
NRG857_00440      CDS       T02068                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
eln  Escherichia coli O83:H1 NRG 857C (AIEC)
Pathway
eln00300  Lysine biosynthesis
eln00550  Peptidoglycan biosynthesis
eln01100  Metabolic pathways
eln01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:eln00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    NRG857_00440 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    NRG857_00440 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    NRG857_00440 (murF)
Enzymes [BR:eln01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     NRG857_00440 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase LpxD ADH_zinc_N
Other DBs
NCBI-ProteinID: ADR25519
UniProt: A0A0H3ED92
Position
96200..97558
AA seq 452 aa
MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIKLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFSDKTALIARLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq 1359 nt   +upstreamnt  +downstreamnt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatattacccttgatgctgtaaccactgacacgcgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggatattgatctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacaggttcctccggcaaaacctccgttaaagagatgacggcggca
attttaagccagtgcggcaacacactttatacggcaggcaatctcaataacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggtgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggttgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cctaatgccgccaacagcgatttcaccgccaccaatatccatgtaacctcacacggtacg
gaatttaccctgcaaacccctacaggtagcgtcgatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccata
aaactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
accgccgctgttcaggttctggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaagcggcaaaa
gctgctggtattgaccgcgtgttaagtgtgggtaaacaaagccatgctatcagcactgcc
agcggcgttggcgaacatttttccgataaaactgcgcttatcgcgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (27)   

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