KEGG   ENZYME: 1.1.1.300Help
Entry
EC 1.1.1.300                Enzyme                                 

Name
NADP-retinol dehydrogenase;
all-trans retinal reductase (ambiguous);
all-trans-retinol dehydrogenase;
NADP(H)-dependent retinol dehydrogenase/reductase;
RDH11;
RDH12;
RDH13;
RDH14;
retinol dehydrogenase 12;
retinol dehydrogenase 14;
retinol dehydrogenase [NADP+];
RalR1;
PSDR1
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
retinol:NADP+ oxidoreductase
Reaction(IUBMB)
retinol + NADP+ = retinal + NADPH + H+ [RN:R08379]
Reaction(KEGG)
Substrate
retinol [CPD:C00473];
NADP+ [CPD:C00006]
Product
retinal [CPD:C00376];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Greater catalytic efficiency in the reductive direction. This observation, and the enzyme's localization at the entrance to the mitochondrial matrix, suggest that it may function to protect mitochondria against oxidative stress associated with the highly reactive retinal produced from dietary beta-carotene by EC 1.13.11.63 (beta-carotene 15,15'-dioxygenase) [2]. Km-values for NADP+ and NADPH are at least 800-fold lower than those for NAD+ and NADH [1,4]. This enzyme differs from EC 1.1.1.105, retinol dehydrogenase, which prefers NAD+ and NADH.
History
EC 1.1.1.300 created 2009
Orthology
K11146  short-chain dehydrogenase/reductase 3
K11152  retinol dehydrogenase 11
K11153  retinol dehydrogenase 12
K11161  retinol dehydrogenase 13
Genes
HSA: 112724(RDH13) 145226(RDH12) 51109(RDH11) 9249(DHRS3)
PTR: 100615509(RDH12) 452986(RDH11) 456293(RDH13) 737006(DHRS3)
PPS: 100971367(DHRS3) 100975938(RDH11) 100976717(RDH12) 100995016(RDH13)
GGO: 101132424(RDH13) 101133959(RDH12) 101134301(RDH11) 101136764(DHRS3)
PON: 100173396(RDH11) 100443109(RDH13) 100444779(RDH12) 100446028(DHRS3)
NLE: 100590397(RDH11) 100592081(RDH12) 100595824(RDH13) 100599507(DHRS3)
MCC: 711195(RDH11) 711438(RDH12) 715548(DHRS3) 722798(RDH13)
MCF: 101865597(RDH12) 101866088(RDH11) 102118061(RDH13) 102142015(DHRS3)
CSAB: 103225584(DHRS3) 103229214(RDH11) 103229215(RDH12) 103235287(RDH13)
RRO: 104664937(RDH12) 104664944(RDH11) 104668927(DHRS3) 104674753(RDH13)
RBB: 108533721(RDH11) 108533722(RDH12) 108539385(DHRS3) 108542524(RDH13) 108542526
CJC: 100386416(DHRS3) 100403102(RDH12) 100406713(RDH13) 103787305(RDH11)
SBQ: 101033448(RDH12) 101039627(DHRS3) 101045253(RDH13) 104649866(RDH11)
MMU: 108841(Rdh13) 17252(Rdh11) 20148(Dhrs3) 77974(Rdh12)
RNO: 313689(Dhrs3) 314264(Rdh12) 361504(Rdh13) 362757(Rdh11)
CGE: 100756186(Dhrs3) 100759393(Rdh13) 100759583(Rdh12) 100759877(Rdh11)
NGI: 103744827(Rdh13) 103747479(Dhrs3) 103749297(Rdh11) 103749298(Rdh12)
HGL: 101707915(Dhrs3) 101715642(Rdh12) 101716026(Rdh13) 101716314(Rdh11)
CCAN: 109683963(Dhrs3) 109694521(Rdh11) 109694522(Rdh12) 109696274(Rdh13)
OCU: 100337836(RDH12) 100344639(RDH13) 100348969 100353716(RDH11) 103352513(DHRS3)
TUP: 102494216(RDH13) 102498009(RDH11) 102498963(RDH12) 102502620(DHRS3) 106735058
CFA: 480366(RDH11) 487436(DHRS3) 490744(RDH12) 611373(RDH13)
AML: 100468936(RDH12) 100469186(RDH11) 100470711(RDH13) 100481198(DHRS3)
UMR: 103666638(DHRS3) 103671847(RDH12) 103671858(RDH11) 103680271(RDH13)
ORO: 101365883(RDH11) 101366366(RDH12) 101370738(DHRS3) 101383491(RDH13)
FCA: 101080307(DHRS3) 101093062(RDH13) 101093193(RDH11) 101093615(RDH12)
PTG: 102958225(RDH12) 102958792(RDH11) 102961855(RDH13) 102970609(DHRS3)
AJU: 106971557(RDH11) 106971559(RDH12) 106980937(RDH13) 106988168(DHRS3)
BTA: 281482(DHRS3) 369021(RDH12) 505995(RDH11) 508082(RDH13)
BOM: 102265772(DHRS3) 102270792(RDH13) 102270801(RDH11) 102271090(RDH12)
BIU: 109564569(RDH12) 109565274(RDH11) 109570447(DHRS3) 109572930(RDH13)
PHD: 102321429(RDH12) 102322389(RDH11) 102323197(DHRS3) 102329922(RDH13)
CHX: 102171883(RDH11) 102173010(RDH12) 102179583(DHRS3) 102181531(RDH13)
OAS: 101109288(DHRS3) 101115127(RDH11) 101115797(RDH12) 101122882 114108681(RDH13)
SSC: 100153020(RDH12) 100154684(RDH11) 100514967(DHRS3) 110261049(RDH13)
CFR: 102511414(RDH13) 102516964(RDH12) 102517215(RDH11) 102524578(DHRS3)
CDK: 105086164(RDH12) 105086165(RDH11) 105098733(RDH13) 105107044(DHRS3)
BACU: 103008561(RDH11) 103009435(RDH12) 103011644(RDH13) 103018059(DHRS3)
LVE: 103082238(DHRS3) 103085939(RDH13) 103090972(RDH12) 103091250(RDH11)
OOR: 101277554(RDH13) 101283025(RDH11) 101283442(RDH12) 101290385(DHRS3)
ECB: 100055280(RDH13) 100055537(DHRS3) 100063295(RDH11) 100063369(RDH12)
EPZ: 103541138(RDH11) 103541139(RDH12) 103552172(DHRS3) 103554723(RDH13)
EAI: 106836659(DHRS3) 106840917(RDH13) 106844772(RDH12) 106844775
MYB: 102246028(RDH13) 102248154(DHRS3) 102260151(RDH11) 102260844(RDH12)
MYD: 102756510(RDH13) 102762827(DHRS3) 102764631(RDH12) 102765110(RDH11)
HAI: 109373731(RDH13) 109381266(DHRS3) 109382035(RDH11) 109382038(RDH12)
RSS: 109434208(RDH13) 109448201(RDH12) 109448378(RDH11) 109460692(DHRS3)
PALE: 102880345(DHRS3) 102886009(RDH11) 102886424(RDH12) 102890503(RDH13)
LAV: 100656973(DHRS3) 100659620(RDH12) 100664643(RDH11) 100668990(RDH13)
TMU: 101355027 101357938 101358377 101360145
MDO: 100010099(DHRS3) 100028370(RDH11) 100028379(RDH12)
SHR: 100913855(DHRS3) 100923639(RDH11) 100923904 100931844(RDH13)
OAA: 100078920(RDH13) 100090663(DHRS3) 100092853 100092857
GGA: 419480(DHRS3) 423274(RDH12)
MGP: 100540846 100541886(DHRS3)
CJO: 107314931(RDH12) 107323359(DHRS3)
APLA: 101792259(DHRS3) 101793409
ACYG: 106031772 106040190(DHRS3)
TGU: 100221618(DHRS3) 100226769(RDH12)
SCAN: 103820840(DHRS3) 103826955
GFR: 102032402(DHRS3) 102032925(RDH12)
FAB: 101814379(DHRS3) 101816060(RDH12)
PHI: 102106104(RDH12) 102110985(DHRS3)
PMAJ: 107205238 107213682(DHRS3)
CCAE: 111930091 111938724(DHRS3)
CCW: 104688342 104693251(DHRS3)
FPG: 101916630(RDH12) 101921484(DHRS3)
FCH: 102055890 102058887(DHRS3)
CLV: 102087489(DHRS3) 102088180 102088364
EGZ: 104122065 104133092(DHRS3)
NNI: 104009010(DHRS3) 104020414
ACUN: 113480412 113487888(DHRS3)
AAM: 106482457(DHRS3) 106483104(RDH12)
ASN: 102370531(DHRS3) 102373718
AMJ: 102567292(RDH12) 102574201(DHRS3)
PSS: 102445977(DHRS3) 102446647
CMY: 102934533(RDH12) 102944040(DHRS3)
CPIC: 101941293(DHRS3) 101950060(RDH12)
ACS: 100556987 100557137(dhrs3) 100557184 100557378 100557577
PVT: 110082355 110082458(DHRS3) 110082559
PBI: 103052660 103054360(DHRS3) 103055029 103056373 112543320
PMUR: 107284674(DHRS3) 107285841
GJA: 107112214(RDH12) 107124081(DHRS3)
XLA: 108697667 444106(rdh13.L) 444269(dhrs3.L)
XTR: 493258(dhrs3) 496409(rdh13)
NPR: 108783931(DHRS3) 108788946(RDH13) 108793980
DRE: 436597(rdh12) 450050(dhrs3b)
SRX: 107705384 107706178 107712670 107712786 107724212 107727205 107727210 107727813 107732076 107732574 107736172 107737702 107741298 107746919 107749419 107756193 107758290
SANH: 107655021 107657757 107675518 107677205 107685629 107686084 107686693 107686694 107687474 107691330 107695397 107696056 107696589 107697223 107700424 107703071
SGH: 107555693 107556114 107566779 107568630(dhrs3) 107585486 107586344 107588523 107588583 107591109 107591613 107593436 107595137 107595155 107599658 107599744
CCAR: 109044936 109050290 109050291 109055081 109059896 109072076 109072700 109077249 109077257 109093510 109099714
IPU: 100528113(rdh13) 108255144(dhrs3) 108255501 108257080 108263330(rdh11) 108268141 108270740(RDH12) 108275517(DHRS3) 108280225
PHYP: 113530392 113534005 113534161(rdh13) 113535992 113537068 113537937(dhrs3) 113540434 113541909(rdh11)
AMEX: 103027802 103033641 103035184 103038275 103038897 103041043 103042050(dhrs3) 103043116 103044420 103044922 111193417
EEE: 113569731 113569822 113570049 113572945 113576255 113581201 113586063 113586576(rdh13) 113587467
TRU: 101064046(dhrs3) 101069118(rdh13) 101071170(rdh12) 101073746 101073971 101078532 101079748
TNG: GSTEN00005665G001 GSTEN00015466G001 GSTEN00015467G001 GSTEN00022954G001 GSTEN00024054G001 GSTEN00025514G001 GSTEN00034558G001
LCO: 104917828 104917935(dhrs3) 104919686(rdh13) 104922588 104922589 104935572(rdh12) 104937271 104939647 109142445
NCC: 104940843 104942382 104946353(rdh13) 104955652(dhrs3) 104955729 104957158 104957588 104957590 104964031
MZE: 101467449 101467758 101469393 101470050(rdh13) 101473687 101474963 101480615(rdh12) 101486960(dhrs3) 112435597
OLA: 101159580(dhrs3) 101164264 101164512(rdh13) 101164605 101167436 101168330 101171076 111946613
XMA: 102218522 102221571(rdh13) 102224795 102225111 102227890(rdh12) 102229237 102234622 102236552 102237356(dhrs3)
PRET: 103456531 103456533 103456786 103458238 103462602 103464767(dhrs3) 103466624 103469853 103477479 103481086(rdh13)
NFU: 107379016 107381485 107383151 107383153 107384894(dhrs3) 107388056(rdh13) 107388796 107391941
KMR: 108228975 108230029 108230278 108231475(dhrs3) 108232585 108237226(rdh13) 108237291 108243166 108243167
CSEM: 103376897 103376898 103377359 103379378 103381277(rdh12) 103381690(rdh13) 103386641(dhrs3)
LCF: 108875326 108876948 108884722 108885195(dhrs3) 108886670(rdh12) 108886781(rdh13) 108900014 108900796 108900797
SDU: 111218329 111219785(rdh13) 111224335 111228451 111233594(dhrs3) 111234073 111237149 111237232 111237248
HCQ: 109513475 109513950 109515570 109515571 109517403(rdh12) 109521619(dhrs3) 109524726 109526512(rdh13)
BPEC: 110157358 110157895 110159576(rdh13) 110160976 110161020 110165520 110170419 110174741(dhrs3) 110175465
MALB: 109962304 109963510(rdh13) 109963732 109971581 109972345(dhrs3) 109973374(rdh12)
SASA: 100196075(rdh12) 100380445(dhrs3) 106561176 106566814 106569221 106570158 106572239 106578408 106578413 106579211(rdh13) 106579697 106582983 106584900 106588337 106593045 106598856(RDH12) 106606092 106611488
OTW: 112215488 112215489 112215877 112218506 112218596 112222076 112223708(rdh13) 112227853 112229755 112232393 112233073 112236125 112248876 112254479 112261120 112264737
SALP: 111953807 111955872 111957126 111966310 111967734(dhrs3) 111969990 111973590 111973591 111974723 111977048 111978483(rdh13) 112071886 112073991 112078006
ELS: 105012697 105013897(dhrs3) 105014061 105015937 105016646 105018873 105019615 105019635 105021270(rdh13) 105022046 105022047 105024242
SFM: 108918261 108919363 108919684 108931697 108933492 108933771(rdh13) 108935518 108935520 108938884 108941899
PKI: 111836935(rdh13) 111837162 111838435 111844126 111845732 111852055 111854295 111856206(rdh12) 111859170
LCM: 102347732(RDH13) 102349654 102353614(RDH12) 102354914 102361459(DHRS3)
CMK: 103175207(rdh12) 103179224(rdh13) 103186371 103187903
BFO: BRAFLDRAFT_105245 BRAFLDRAFT_115143 BRAFLDRAFT_118764 BRAFLDRAFT_139278 BRAFLDRAFT_150455 BRAFLDRAFT_202301 BRAFLDRAFT_202354 BRAFLDRAFT_202467 BRAFLDRAFT_221193 BRAFLDRAFT_239950 BRAFLDRAFT_239978 BRAFLDRAFT_240038 BRAFLDRAFT_247684 BRAFLDRAFT_68368 BRAFLDRAFT_68398 BRAFLDRAFT_68404
SPU: 589814 593999
APLC: 110976160 110982277 110983988 110984991 110988383 110989984
SKO: 100368032 100370050 100370906 100375139 102802726 102804882
DAN: Dana_GF13192
DPE: 6600030
DSE: Dsec_GM18707
DWI: 6641201 6642626 6642799 6646241
DGR: Dgri_GH24058
DMO: Dmoj_GI15186
DVI: Dvir_GJ17066 Dvir_GJ17067
BIM: 100745829
BTER: 100650146
SOC: 105195606 105195607 105200470 105206052 105206054
MPHA: 105831820 105832887 105833295 105834093 105837415 105837568 105841029
AEC: 105144537 105145519
ACEP: 105618447 105626379
PBAR: 105422088 105428632 105428633 105431710
HST: 105188653 105191531
DQU: 106748801
CFO: 105253345 105255509
LHU: 105669154 105669716 105671265 105676414 105677889
PGC: 109852106 109854255 109857489 109857490
OBO: 105276258 105276949
MDL: 103574520 103574614
TCA: 655069 655707 664039 664051 664326
NVL: 108556542 108563419 108563997 108564002
BMOR: 101735372 101735502 105841510
DPL: KGM_203541 KGM_205840 KGM_208720 KGM_208721 KGM_211391 KGM_213154
PMAC: 106719654
PRAP: 110999155
HAW: 110371776
TNL: 113492848 113492849
PXY: 105381830 105382636 105397274 105397883
API: 100161693 100163758 100166388
DNX: 107171055 107171967
CLEC: 106662430 106665883
PHU: Phum_PHUM112910 Phum_PHUM490670
ZNE: 110834190 110834193 110835668 110836709 110836719 110839626 110839880
FCD: 110842196 110844264 110845876 110852259 110854601 110854972 110856461 110857496 110859244 110863209 110863210 110863470
DPX: DAPPUDRAFT_307583 DAPPUDRAFT_41849 DAPPUDRAFT_93620
ISC: IscW_ISCW000502 IscW_ISCW007540 IscW_ISCW008433 IscW_ISCW010995 IscW_ISCW011012 IscW_ISCW013705 IscW_ISCW014854 IscW_ISCW016461 IscW_ISCW016462 IscW_ISCW018859 IscW_ISCW020262 IscW_ISCW020263
DPTE: 113788995 113789392 113791515
NAI: NECAME_09426 NECAME_11316
TSP: Tsp_04022
HRO: HELRODRAFT_103444 HELRODRAFT_109820 HELRODRAFT_168674 HELRODRAFT_185285
LGI: LOTGIDRAFT_197176 LOTGIDRAFT_208859
CRG: 105320167 105323007 105335028 105341249 105342208 105345933
MYI: 110449186 110450669 110461358 110462738
OBI: 106870606 106874866 106875378 106876816 106878107 106879995 106880895 106883220
LAK: 106156832 106157569 106164481 106170304 106170305 106171422 106175349 106181051 112041252
SMM: Smp_032370 Smp_076580 Smp_078600 Smp_120070 Smp_139680 Smp_139700 Smp_179850 Smp_203950
SHX: MS3_08851 MS3_08853 MS3_10219 MS3_10220 MS3_10550 MS3_11246
OVI: T265_03704 T265_07291 T265_11059 T265_11060 T265_15439
EGL: EGR_02372
EPA: 110235696 110241161
ADF: 107332470 107348672
PDAM: 113667168 113681427
SPIS: 111319399 111346361 111347408
AQU: 100631596 100631723 100633112 100637836 100641757 100641884 105313865
ALY: ARALYDRAFT_474887
CRB: 17881231 17883393 17890094 17895493
CSAT: 104704096 104714827 104717878 104722594 104731057 104773949
EUS: EUTSA_v10013579mg EUTSA_v10025670mg
BRP: 103838175 103838194 103847440 103861459 103861680
BNA: 106356581 106364223 106364224 106365318 106372593 106374450 106377123 106414115 106440563 111207462 111211861
BOE: 106292972 106303521 106316697 106316796 106331860
THJ: 104809317 104816290 104823251 104827006
CPAP: 110807030 110820086
CIT: 102607364 102619498
CIC: CICLE_v10012197mg CICLE_v10021041mg
TCC: 18597799
GRA: 105779735 105787642 105791323 105799868 105800028 105801884
GHI: 107889705 107890882 107891036 107899294 107904516 107911448 107923740 107926626 107933597 107948830 107953529
GAB: 108454068 108456218 108456254 108458191 108485720
DZI: 111287346 111289924 111290710 111297915 111311923 111315787
EGR: 104426240 104436454 104442518
GMX: 100777167 100781156 100794347 100799729 100801384 100801849 102670316
PVU: PHAVU_001G169500g PHAVU_002G301600g PHAVU_003G203300g PHAVU_009G175600g
VRA: 106757059 106761028 106766878
VAR: 108322902 108322985 108324143 108330236 108346036
CCAJ: 109797500 109800661 109806370 109809382 109818471
MTR: MTR_4g105310 MTR_8g099995
CAM: 101509179
LJA: Lj1g3v0342000.1(Lj1g3v0342000.1) Lj2g3v1016620.1(Lj2g3v1016620.1) Lj4g3v3014530.1(Lj4g3v3014530.1) Lj5g3v0614340.2(Lj5g3v0614340.2)
ADU: 107472504 107491683 107494885
AIP: 107632047 107648182
LANG: 109330692 109334978 109335934 109348420 109357067 109361037
FVE: 101295243
PPER: 18772531
MDM: 103410296 103420014 103427570 103438339 103454764
PXB: 103931084 103942177 103952981 103963565 103963888
ZJU: 107416659 107423539 107431100
CSV: 101205956 101209698
CMO: 103486400 103502388
MCHA: 111006882 111014975
CMAX: 111465182 111469067 111470041 111482112 111485650
CMOS: 111429765 111442120 111450056
CPEP: 111780052 111791471 111800669 111808357
RCU: 8269384 8278318 8280993
JCU: 105636270
HBR: 110664761
MESC: 110616519 110622567 110631226
POP: 7457761 7458067 7484371 7487251
JRE: 109006782
VVI: 100261623 100263820
SLY: 101244694 101255321 101258297 101263363
SPEN: 107002316 107027191 107028249 107029428
SOT: 102583799 102595507 102596958
CANN: 107841643 107842955 107842976 107843337
NTA: 107768761 107788371 107793887 107807182 107810105 107829977
NSY: 104215259
NTO: 104093517 104112087 104115366 104117436
INI: 109157983 109160460 109165169
SIND: 105179115 105179385
OEU: 111405301
HAN: 110864472 110867292 110868424 110883127 110898239 110904384
LSV: 111887462 111911734
CCAV: 112507512 112521483 112528970
DCR: 108196149 108203958 108215406 108225028 108226541 108226691
BVG: 104892580
CQI: 110696937 110700352 110716435 110727600 110735312
NNU: 104591450 104591452 104594289 104594591 104604735 104610245 104610803
PSOM: 113276208 113282496 113286418 113326206 113328666 113328686
DOSA: Os10t0547900-01(Os10g0547900)
OBR: 102710819 102718731
BDI: 100827273 100836169
ATS: 109754769(LOC109754769) 109772785(LOC109772785)
SBI: 8062837 8078000
ZMA: 100285880
SITA: 101761163 101770964 101782664
PDA: 103695766 103701414 103707701 103708202 103714170
EGU: 105043433 105054114 105054614 105056971
MUS: 103972617 103990674 103991720 103993218
DCT: 110110576
PEQ: 110022984 110026519 110027095 110027746
AOF: 109826635 109837964 109843305 109849528 109850082
ATR: 110006661 18422851 18430770 18447709
SMO: SELMODRAFT_114160 SELMODRAFT_114437 SELMODRAFT_114488 SELMODRAFT_116561 SELMODRAFT_136252 SELMODRAFT_139089 SELMODRAFT_17042 SELMODRAFT_410942 SELMODRAFT_420551
PPP: 112275358 112289136 112295066
CRE: CHLREDRAFT_176680 CHLREDRAFT_191453
VCN: VOLCADRAFT_119590 VOLCADRAFT_65341 VOLCADRAFT_79467 VOLCADRAFT_93745
MNG: MNEG_12120 MNEG_12271
OTA: OT_ostta01g05890 OT_ostta01g05930 OT_ostta13g02190
BPG: Bathy04g02560
CSL: COCSUDRAFT_52566 COCSUDRAFT_66319
CVR: CHLNCDRAFT_142357
APRO: F751_1025
GSL: Gasu_17830 Gasu_34300 Gasu_50400
CCP: CHC_T00010090001
ZTR: MYCGRDRAFT_96726
PSQ: PUNSTDRAFT_122742 PUNSTDRAFT_55413
MRR: Moror_10748
DFA: DFA_01654
EIV: EIN_296880 EIN_374850 EIN_383490
ACAN: ACA1_088210 ACA1_088340 ACA1_381490
TET: TTHERM_00152010 TTHERM_00152020 TTHERM_00216130 TTHERM_00947520
PTM: GSPATT00000448001 GSPATT00003749001 GSPATT00012579001 GSPATT00020708001 GSPATT00039126001 PTMB.94
FCY: FRACYDRAFT_185817 FRACYDRAFT_244068 FRACYDRAFT_255573
SPAR: SPRG_06996 SPRG_07905 SPRG_13964
GTT: GUITHDRAFT_108486
NGR: NAEGRDRAFT_30072 NAEGRDRAFT_32453 NAEGRDRAFT_33289 NAEGRDRAFT_44570 NAEGRDRAFT_44843 NAEGRDRAFT_58626 NAEGRDRAFT_76802
KAK: Kalk_16770
OME: OLMES_2705
SOK: D0B54_08240
SALN: SALB1_1281
BSED: DN745_16140
PDH: B9T62_23125
HSW: Hsw_2466
FLM: MY04_4115
 » show all
Taxonomy
Reference
1  [PMID:15865448]
  Authors
Belyaeva OV, Korkina OV, Stetsenko AV, Kim T, Nelson PS, Kedishvili NY
  Title
Biochemical properties of purified human retinol dehydrogenase 12 (RDH12): catalytic efficiency toward retinoids and C9 aldehydes and effects of cellular retinol-binding protein type I (CRBPI) and cellular retinaldehyde-binding protein (CRALBP) on the oxidation and reduction of retinoids.
  Journal
Biochemistry 44:7035-47 (2005)
DOI:10.1021/bi050226k
  Sequence
[hsa:145226]
Reference
2  [PMID:18039331]
  Authors
Belyaeva OV, Korkina OV, Stetsenko AV, Kedishvili NY
  Title
Human retinol dehydrogenase 13 (RDH13) is a mitochondrial short-chain dehydrogenase/reductase with a retinaldehyde reductase activity.
  Journal
FEBS J 275:138-47 (2008)
DOI:10.1111/j.1742-4658.2007.06184.x
  Sequence
[hsa:112724]
Reference
3  [PMID:9705317]
  Authors
Haeseleer F, Huang J, Lebioda L, Saari JC, Palczewski K
  Title
Molecular characterization of a novel short-chain dehydrogenase/reductase that reduces all-trans-retinal.
  Journal
J Biol Chem 273:21790-9 (1998)
DOI:10.1074/jbc.273.34.21790
  Sequence
[hsa:9249] [mmu:20148] [bta:281482]
Reference
4  [PMID:12036956]
  Authors
Kedishvili NY, Chumakova OV, Chetyrkin SV, Belyaeva OV, Lapshina EA, Lin DW, Matsumura M, Nelson PS
  Title
Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1).
  Journal
J Biol Chem 277:28909-15 (2002)
DOI:10.1074/jbc.M202588200
  Sequence
[hsa:51109]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.300
IUBMB Enzyme Nomenclature: 1.1.1.300
ExPASy - ENZYME nomenclature database: 1.1.1.300
BRENDA, the Enzyme Database: 1.1.1.300

  All links  
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (4832)   
   KEGG ORTHOLOGY (4)   
   KEGG GENES (1185)   
   KEGG MGENES (871)   
   RefGene (2772)   
Protein sequence (167)   
   UniProt (63)   
   SWISS-PROT (31)   
   RefSeq(pep) (73)   
DNA sequence (88)   
   RefSeq(nuc) (77)   
   GenBank (8)   
   EMBL (3)   
Protein domain (2)   
   InterPro (2)   
All databases (5096)   

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