KEGG   ENZYME: 4.1.2.21Help
Entry
EC 4.1.2.21                 Enzyme                                 

Name
2-dehydro-3-deoxy-6-phosphogalactonate aldolase;
6-phospho-2-keto-3-deoxygalactonate aldolase;
phospho-2-keto-3-deoxygalactonate aldolase;
2-keto-3-deoxy-6-phosphogalactonic aldolase;
phospho-2-keto-3-deoxygalactonic aldolase;
2-keto-3-deoxy-6-phosphogalactonic acid aldolase;
(KDPGal)aldolase;
2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase;
2-dehydro-3-deoxy-D-galactonate-6-phosphate D-glyceraldehyde-3-phosphate-lyase (pyruvate-forming)
Class
Lyases;
Carbon-carbon lyases;
Aldehyde-lyases
BRITE hierarchy
Sysname
2-dehydro-3-deoxy-6-phospho-D-galactonate D-glyceraldehyde-3-phospho-lyase (pyruvate-forming)
Reaction(IUBMB)
2-dehydro-3-deoxy-6-phospho-D-galactonate = pyruvate + D-glyceraldehyde 3-phosphate [RN:R01064]
Reaction(KEGG)
Substrate
2-dehydro-3-deoxy-6-phospho-D-galactonate [CPD:C01286]
Product
pyruvate [CPD:C00022];
D-glyceraldehyde 3-phosphate [CPD:C00118]
Comment
The enzyme catalyses the last reaction in a D-galactose degradation pathway. cf. EC 4.1.2.55, 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase.
History
EC 4.1.2.21 created 1972, modified 2014
Pathway
ec00052  Galactose metabolism
ec01100  Metabolic pathways
Orthology
K01631  2-dehydro-3-deoxyphosphogalactonate aldolase
Genes
ECO: b4477(dgoA)
ECJ: JW5628(dgoA)
ECD: ECDH10B_3879(dgoA)
EBW: BWG_3383(dgoA)
ECOK: ECMDS42_3129(dgoA)
EOJ: ECO26_4889(dgoA)
EOI: ECO111_4520(dgoA)
EOH: ECO103_4465(dgoA)
ECG: E2348C_4004(dgoA)
ESO: O3O_25565
ESM: O3M_00055
ESL: O3K_00055
ELH: ETEC_3983
ECC: c4777
ECV: APECO1_2764(dgoA)
ECY: ECSE_3979
ECR: ECIAI1_3871(dgoA)
ECK: EC55989_4162(dgoA)
ECT: ECIAI39_4295(dgoA)
EOC: CE10_4336(dgoA)
EUM: ECUMN_4224(dgoA)
ELO: EC042_4049(dgoA)
EBR: ECB_03576(dgoA) ECB_03722
EKF: KO11_03500(dgoA)
EDJ: ECDH1ME8569_3580(dgoA)
EIH: ECOK1_4300(eda)
ENA: ECNA114_3843(dgoA1) ECNA114_4140(dgoA2)
ELW: ECW_m3992(dgoA)
ELL: WFL_19510(dgoA)
ELC: i14_4207(dgoA) i14_4371
ELD: i02_4207(dgoA) i02_4371
EBL: ECD_03576(dgoA) ECD_03722
EBE: B21_03520(dgoA) B21_03671(ybl193)
ELF: LF82_0472(dgoA) LF82_599
ECOI: ECOPMV1_04032(dgoA_1) ECOPMV1_04189(dgoA_2)
EFE: EFER_3651 EFER_3988(dgoA)
SEY: SL1344_3795(dgoA)
SEB: STM474_4006(dgoA)
SEF: UMN798_4163(dgoA)
SENR: STMDT2_37081(dgoA)
SENI: CY43_19870
SEK: SSPA3433b
SEI: SPC_3915
SEC: SCH_3746(dgoA)
SHB: SU5_04306
SED: SeD_A4220
SEG: SG3603
SEL: SPUL_3738
SET: SEN3645
SENA: AU38_18615
SENO: AU37_18805
SENV: AU39_18810
SENQ: AU40_20980
SENL: IY59_19255
SEEP: I137_17965
SENE: IA1_18625
SFN: SFy_5372
SFS: SFyv_5443
SFT: NCTC1_04065(dgoA)
ENC: ECL_00010
EEC: EcWSU1_00010(dgoA)
ECLX: LI66_00050
ECLY: LI62_00330
ECLZ: LI64_00070
ESA: ESA_03968
CSK: ES15_3870(dgoA)
CTU: CTU_00460(dgoA) CTU_06620(dgoA)
KPN: KPN_04096(dgoA) KPN_04797
KPU: KP1_0755 KP1_5474(dgoA)
KPE: KPK_2035(dgoA)
KPR: KPR_0010(dgoA) KPR_0877
KPX: PMK1_01603(dgoA_1) PMK1_02258(dgoA_2)
KPNK: BN49_0010(dgoA) BN49_4396
KVA: Kvar_1929
CKO: CKO_00004
CRO: ROD_40321(dgoA) ROD_48441(dgoA)
CAMA: F384_20185
EBT: EBL_c00070(dgoA)
EBF: D782_0028
PSTS: E05_28620(dgoA) E05_28630
YIN: CH53_1714
YRO: CH64_1285
SPE: Spro_0043
SMAF: D781_2938
RAA: Q7S_13405
ECA: ECA4417(dgoA2)
PATR: EV46_21995
PATO: GZ59_45140(dgoA2)
PEC: W5S_0024
SOD: Sant_0084
DDQ: DDI_1149
EBI: EbC_45580(dgoA)
XDO: XDD1_1929(dgoA)
XPO: XPG1_2172(dgoA)
LRI: NCTC12151_00070(dgoA_1) NCTC12151_00913(dgoA_2)
XCC: XCC1747(dgoA)
XCB: XC_2487
XCA: xcc-b100_2514(dgoA)
XCP: XCR_1987
XCV: XCV1797(dgoA)
XAX: XACM_1788(dgoA)
XAC: XAC1766(dgoA)
XCI: XCAW_02302(eda)
XFU: XFF4834R_chr27460(dgoA)
XOO: XOO2917(dgoA)
XOM: XOO2768(XOO2768)
XOP: PXO_00120
XOR: XOC_2153
XAL: XALC_1190(dgoA)
XPH: XppCFBP6546_19120(XppCFBP6546P_19120)
PSUW: WQ53_13320
VVY: VVA1575
PST: PSPTO_2178(eda-2)
PSB: Psyr_1988
PSYR: N018_09270
PSP: PSPPH_1957(eda2)
PFS: PFLU_0031
PFC: PflA506_0030(dgoA)
PFW: PF1751_v1c00310(dgoA)
PFB: VO64_3077
PMAN: OU5_1767
PSES: PSCI_3816(eda)
PSEM: TO66_09085
PANR: A7J50_0032
PSIL: PMA3_06745
AVN: Avin_51330(dgoA)
AVL: AvCA_51330(dgoA)
AVD: AvCA6_51330(dgoA)
ACX: Achr_39600(dgoA)
PAT: Patl_0899
SAGA: M5M_16935
GAI: IMCC3135_21230(dgoA_1) IMCC3135_28770(dgoA_2)
HEL: HELO_1780(dgoA)
HAM: HALO2023
HCO: LOKO_03163(dgoA)
HBE: BEI_0975(dgoA)
SALN: SALB1_2558
RSO: RSc2752(dgoAa)
RSL: RPSI07_0757(dgoA)
RSM: CMR15_10661(dgoA)
RSE: F504_2678
RPI: Rpic_2991
RIN: ACS15_3034(dgoA)
BMA: BMA2488
BMAL: DM55_680
BMAE: DM78_660
BMAQ: DM76_661
BMAI: DM57_1258
BMAF: DM51_2122
BMAZ: BM44_73
BMAB: BM45_2649
BPS: BPSL2970
BPM: BURPS1710b_3487(eda-2)
BPSE: BDL_2470
BPSM: BBQ_335
BPSU: BBN_463
BPSD: BBX_867
BPK: BBK_1952
BPSH: DR55_1546
BPSA: BBU_2588
BPSO: X996_1185
BTE: BTH_I1177
BTQ: BTQ_2753
BTJ: BTJ_2942
BTZ: BTL_873
BTD: BTI_638
BTV: BTHA_963
BTHE: BTN_516
BTHM: BTRA_1080
BTHA: DR62_688
BTHL: BG87_1069
BOK: DM82_2633
BOC: BG90_2100
BVE: AK36_212
BCN: Bcen_0136
BCJ: BCAL3407
BCEN: DM39_431
BCEW: DM40_1323
BCEO: I35_0468
BAM: Bamb_0520
BMU: Bmul_2766
BMJ: BMULJ_00471(eda)
BMK: DM80_1051
BMUL: NP80_655
BCT: GEM_2903
BCED: DM42_1223
BDL: AK34_2526
BCON: NL30_21000
BUB: BW23_1118
BLAT: WK25_02985
BTEI: WS51_13445
BSEM: WJ12_02715
BPSL: WS57_20535
BMEC: WJ16_02705
BSTG: WT74_03035
BGP: BGL_1c05030(dgoA)
BGU: KS03_1448
BGO: BM43_1944
BUL: BW21_734
BXE: Bxe_A0544
BXB: DR64_2719
BPH: Bphy_2617
BFN: OI25_2003
PLG: NCTC10937_03312(dgoA)
BHZ: ACR54_00435(dgoA)
AXX: ERS451415_05549(dgoA_2)
AMIM: MIM_c39560
ODI: ODI_R1139
POL: Bpro_3535
AAV: Aave_2245
AAA: Acav_2895
RTA: Rta_11470
LIM: L103DPR2_01306(dgoA)
LIH: L63ED372_00922(dgoA)
HSE: Hsero_1030(dgoAa)
HRB: Hrubri_0828(dgoAa)
CFU: CFU_3989(eda2)
CARE: LT85_4541
MLO: mlr4743
MES: Meso_0846
AMIH: CO731_00806(dgoA_1) CO731_04165(dgoA_2)
RBS: RHODOSMS8_01707(dgoA)
SME: SMc00882
SMX: SM11_chr0477(dgoA)
SMI: BN406_00478(dgoA)
SMEL: SM2011_c00882(dgoA)
SMER: DU99_04250
SMD: Smed_0436
RHI: NGR_c04350(dgoA)
SFH: SFHH103_00502(dgoA)
SFD: USDA257_c05350(dgoA)
SAME: SAMCFNEI73_Ch0858(dgoA)
EAD: OV14_1756(dgoA)
ATU: Atu0703(kdgA)
ARA: Arad_1102(kdgA)
ATF: Ach5_06270(kdgA)
AVI: Avi_3915
AGR: AGROH133_04265(kdgA)
RET: RHE_CH00853(kdgA)
REC: RHECIAT_CH0000942(dgoA)
REL: REMIM1_CH00866(dgoA)
REP: IE4803_CH00864(dgoA)
REI: IE4771_CH00891(dgoA)
RLE: RL0915(dgoA)
RLG: Rleg_0544
RIR: BN877_I0679(dgoA)
RGA: RGR602_CH00911(dgoA)
RHN: AMJ98_CH00872(dgoA)
RPHA: AMC79_CH00882(dgoA)
RHT: NT26_3707(dgoA)
RHX: AMK02_CH00892(dgoA)
RHK: Kim5_CH00972(dgoA)
SHZ: shn_03760
BME: BMEII0358
BMEL: DK63_2881
BMEE: DK62_2516
BMF: BAB2_0296
BABO: DK55_2288
BABR: DO74_2708
BABT: DK49_2943
BABB: DK48_2404
BABU: DK53_2299
BABS: DK51_2877
BABC: DO78_2762
BMS: BRA0938
BSZ: DK67_2891
BOV: BOV_A0880
BCAR: DK60_2629
BCAS: DA85_14975
BMR: BMI_II932
BPP: BPI_II994
BPV: DK65_2714
OAN: Oant_1423
OAH: DR92_989
BJA: bll7287(dgoA)
BRA: BRADO1754(dgoA)
BBT: BBta_2069(dgoA)
BRS: S23_59120(dgoA)
AOL: S58_57890
BRAD: BF49_2825
BRO: BRAD285_5543(dgoA)
AZC: AZC_4410
SNO: Snov_4074
MET: M446_4621
MNO: Mnod_4805
MOR: MOC_0053
MAQU: Maq22A_c05985(eda)
BID: Bind_2871
PHL: KKY_211
BVR: BVIR_356
MMED: Mame_03677(dgoA)
HDI: HDIA_4617(dgoA)
CCR: CC_0784
CAK: Caul_1286
CSE: Cseg_3578
PZU: PHZ_c2071(eda)
RSP: RSP_3301(eda)
JAN: Jann_3832
RDE: RD1_2868(dgoA)
RLI: RLO149_c015730(dgoA)
PAMN: JCM7685_2987(dgoA)
DSH: Dshi_1241(dgoA)
PSF: PSE_1299(dogA) PSE_1895(dgoA)
PGA: PGA1_c07350(dgoA)
PGL: PGA2_c06850(dgoA)
PGD: Gal_02757
PHP: PhaeoP97_02457(dgoA)
PPIC: PhaeoP14_00655(dgoA)
OAR: OA238_c36010(dgoA)
OTM: OSB_28080(dgoA)
PTP: RCA23_c01410(dgoA)
SPSE: SULPSESMR1_02139(dgoA)
LVS: LOKVESSMR4R_02337(dgoA)
AHT: ANTHELSMS3_01220(dgoA)
HBA: Hbal_2712
SAL: Sala_0744
SPHU: SPPYR_0441(dgoA)
SPHM: G432_09675
STAX: MC45_07840
SPHI: TS85_12945
SSAN: NX02_22815
SJP: SJA_C1-06000(dgoAa)
SPHB: EP837_02118(dgoA)
SPHR: BSY17_3793
SINB: SIDU_10690
SPHT: K426_16875
ADO: A6F68_00757(dgoA)
ACR: Acry_2597
AMV: ACMV_29220(dgoA)
GDI: GDI2172(dgoA)
GDJ: Gdia_0391
AZL: AZL_c04400(dgoAa)
ALI: AZOLI_p30273(dgoA)
ABS: AZOBR_p210117(dgoA)
TMO: TMO_3368(dgoA)
TXI: TH3_12940
ROP: ROP_11620(dgoA)
AAI: AARI_31740(dgoA)
AOI: AORI_3000(dgoA)
GBA: J421_4307
 » show all
Taxonomy
Reference
1
  Authors
Shuster, C.W.
  Title
2-Keto-3-deoxy-6-phosphogalactonic acid aldolase.
  Journal
Methods Enzymol 9:524-528 (1966)
Other DBs
ExplorEnz - The Enzyme Database: 4.1.2.21
IUBMB Enzyme Nomenclature: 4.1.2.21
ExPASy - ENZYME nomenclature database: 4.1.2.21
BRENDA, the Enzyme Database: 4.1.2.21
CAS: 9030-99-3

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