KEGG   ENZYME: 4.2.1.6Help
Entry
EC 4.2.1.6                  Enzyme                                 

Name
galactonate dehydratase;
D-galactonate dehydrase;
D-galactonate dehydratase;
D-galactonate hydro-lyase
Class
Lyases;
Carbon-oxygen lyases;
Hydro-lyases
BRITE hierarchy
Sysname
D-galactonate hydro-lyase (2-dehydro-3-deoxy-D-galactonate-forming)
Reaction(IUBMB)
D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H2O [RN:R03033]
Reaction(KEGG)
Substrate
D-galactonate [CPD:C00880]
Product
2-dehydro-3-deoxy-D-galactonate [CPD:C01216];
H2O [CPD:C00001]
Comment
The enzyme shows no activity with D-gluconate [2]. cf. EC 4.2.1.140, gluconate/galactonate dehydratase.
History
EC 4.2.1.6 created 1961
Pathway
ec00052  Galactose metabolism
ec01100  Metabolic pathways
ec01120  Microbial metabolism in diverse environments
Orthology
K01684  galactonate dehydratase
Genes
SLB: AWJ20_3368
TTT: THITE_2052176
MGR: MGG_07935
TMN: UCRPA7_1101
SSCK: SPSK_04317
FGR: FGSG_03955
FPU: FPSE_05319
FVR: FVEG_10086
FOX: FOXG_11724 FOXG_17410
NHE: NECHADRAFT_64742
MAW: MAC_05131
MAJ: MAA_09626
CMT: CCM_04918
MBE: MBM_02236
ANI: AN4828.2
ANG: ANI_1_552184(An04g02760) ANI_1_578164(An18g04330)
ABE: ARB_05623
TVE: TRV_06723
PTE: PTT_14654
CNE: CNI02060
CNB: CNBH1940
ABP: AGABI1DRAFT122149(AGABI1DRAFT_122149)
ABV: AGABI2DRAFT187049(AGABI2DRAFT_187049)
ECO: b4478(dgoD)
ECJ: JW5629(dgoD)
ECD: ECDH10B_3878(dgoD)
EBW: BWG_3382(dgoD)
ECOK: ECMDS42_3128(dgoD)
EOI: ECO111_4519(dgoD)
EOH: ECO103_4466(dgoD)
ESO: O3O_25560
ESM: O3M_00060
ESL: O3K_00060
ELH: ETEC_3982
ECP: ECP_3893
ECI: UTI89_C4243(dgoA)
ECV: APECO1_2765(dgoD)
ECY: ECSE_3978
ECR: ECIAI1_3870(dgoD)
ECQ: ECED1_4383(dgoD)
ECK: EC55989_4161(dgoD)
ECT: ECIAI39_4294(dgoD)
EOC: CE10_4335(dgoD)
EUM: ECUMN_4223(dgoD)
ECZ: ECS88_4115(dgoD)
ELO: EC042_4048(dgoD)
ESE: ECSF_3536
EBR: ECB_03575(dgoD)
EBD: ECBD_0011
EKF: KO11_03495(dgoD)
EAB: ECABU_c41740(dgoD)
EDJ: ECDH1ME8569_3579(dgoD)
ENA: ECNA114_3842(dgoD)
ELW: ECW_m3991(dgoD)
ELL: WFL_19505(dgoD)
ELC: i14_4206(rspA)
ELD: i02_4206(rspA)
ELP: P12B_c3826(dgoD)
EBL: ECD_03575(dgoD)
EBE: B21_03519(dgoD)
ELF: LF82_0473(dgoD)
ECOI: ECOPMV1_04031(dgoD)
ECOJ: P423_20505
ECOS: EC958_4165(dgoA)
EFE: EFER_3987(dgoD)
STM: STM3828(dgoA)
SEO: STM14_4620(dgoA)
SEY: SL1344_3794(dgoD)
SEJ: STMUK_3815(dgoA)
SEB: STM474_4005(dgoA)
SEF: UMN798_4162(dgoA)
SENR: STMDT2_37071(dgoA)
SEND: DT104_38131(dgoA)
SENI: CY43_19865
SEK: SSPA3433a(dgoA)
SEI: SPC_3914(dgoA)
SEC: SCH_3745(dgoA)
SHB: SU5_04305
SED: SeD_A4219
SEG: SG3604(dgoA)
SEL: SPUL_3739(dgoA)
SEGA: SPUCDC_3725(dgoA)
SET: SEN3644(dgoA)
SENA: AU38_18610
SENO: AU37_18800
SENV: AU39_18805
SENQ: AU40_20975
SENL: IY59_19250
SEEP: I137_17970
SENB: BN855_39160(dgoA)
SENE: IA1_18620
SFT: NCTC1_04066(dgoD_1) NCTC1_04067(dgoD_2)
ENC: ECL_00011
ECLO: ENC_03830
EEC: EcWSU1_00011(dgoD1)
ECLX: LI66_00055
ECLY: LI62_00335
ECLZ: LI64_00075
ESA: ESA_03967
CSK: ES15_3869(dgoD)
CTU: CTU_00470(dgoD)
KPN: KPN_04095(dgoD)
KPU: KP1_5473(dgoD)
KPP: A79E_0011
KPT: VK055_3369(dgoD)
KPE: KPK_2036
KPR: KPR_0011(dgoD)
KPJ: N559_0045
KPX: PMK1_01602(dgoD)
KPNU: LI86_00055
KPNK: BN49_0011(dgoD)
KVA: Kvar_1930
KOX: KOX_06525
KOE: A225_5778
EAE: EAE_06985
EAR: CCG32609
CRO: ROD_40331(dgoD)
CAMA: F384_20180
PSTS: E05_28610(dgoD)
YEE: YE5303_16181(dgoD)
YIN: CH53_1713(dgoD)
YRO: CH64_1284(dgoD)
SPE: Spro_0044
RAA: Q7S_13400
ECA: ECA2965 ECA4416(dgoA1)
PATO: GZ59_29690 GZ59_45130(dgoA1)
PCT: PC1_2688
DDQ: DDI_1150
EBI: EbC_45570(dgoD)
XDO: XDD1_1930(dgoD)
XPO: XPG1_2173(dgoD)
LRI: NCTC12151_00914(dgoD_1)
XCC: XCC1746(dgoA)
XCB: XC_2488
XCA: xcc-b100_2515(dgoD)
XCP: XCR_1986
XCV: XCV1796(dgoD)
XAX: XACM_1787(dgoD)
XAC: XAC1765(dgoA)
XCI: XCAW_02303(dgoA)
XFU: XFF4834R_chr27470(dgoD)
XOM: XOO2769(XOO2769)
XOP: PXO_00121
XOR: XOC_2152
XAL: XALC_1189(dgoD)
XPH: XppCFBP6546_19115(XppCFBP6546P_19115)
PSUW: WQ53_13315
LCP: LC55x_2854(dgoD)
LGU: LG3211_0292(dgoD)
VVY: VVA1580
VNI: VIBNI_A1756(dgoD)
PSB: Psyr_1989
PSYR: N018_09275
PSP: PSPPH_1958(dgoD)
PFS: PFLU_0032(dgoD)
PFC: PflA506_0031(dgoD)
PFW: PF1751_v1c00320(dgoD)
PFB: VO64_3078
PMAN: OU5_1766(dgoD)
PSES: PSCI_3817
PSEM: TO66_09090
PANR: A7J50_0033
PSIL: PMA3_06750
AVN: Avin_51320(galD)
AVL: AvCA_51320(galD)
AVD: AvCA6_51320(galD)
ACX: Achr_39590(galD)
SAGA: M5M_16950
GAI: IMCC3135_02500(dgoD_1) IMCC3135_18545(dgoD_3) IMCC3135_19935(dgoD_4)
CSA: Csal_2615
HEL: HELO_1779(dgoD)
HAM: HALO2025
HCO: LOKO_03161(dgoD)
HBE: BEI_0974(dgoD)
SALN: SALB1_2559
RSO: RSc2751(dgoAb)
RSL: RPSI07_0758(dgoD)
RSM: CMR15_10662(dgoD)
RSE: F504_2677
RPI: Rpic_2990
RIN: ACS15_3033(dgoD)
CGD: CR3_3728(dgoD)
BMA: BMA0254(dgoA)
BMV: BMASAVP1_A2694(dgoA)
BMAL: DM55_1652
BMAE: DM78_341
BMAQ: DM76_1630
BMAI: DM57_2284
BMAF: DM51_54
BMAZ: BM44_830
BMAB: BM45_573
BPS: BPSL0699
BPM: BURPS1710b_0918(dgoA)
BPSE: BDL_1305
BPSM: BBQ_2728
BPSU: BBN_2851
BPSD: BBX_3252(dgoD)
BPK: BBK_786(dgoD)
BPSH: DR55_394
BPSA: BBU_1452(dgoD)
BPSO: X996_1
BUT: X994_2016
BTE: BTH_I0611
BTQ: BTQ_631(dgoD)
BTJ: BTJ_1854(dgoD)
BTZ: BTL_3090
BTD: BTI_3089(dgoD)
BTV: BTHA_3373
BTHE: BTN_1622
BTHM: BTRA_3433(dgoD)
BTHA: DR62_1809
BTHL: BG87_3283
BOK: DM82_129
BOC: BG90_893
BVE: AK36_1225
BCN: Bcen_2055
BCJ: BCAL0937
BCEN: DM39_2757
BCEW: DM40_291
BCEO: I35_2731
BAM: Bamb_2719
BMU: Bmul_0631
BMJ: BMULJ_02629(dgoA)
BMK: DM80_2253
BMUL: NP80_2801
BCT: GEM_0771
BCED: DM42_2405
BCON: NL30_26425
BUB: BW23_2225
BLAT: WK25_12950
BTEI: WS51_23745
BSEM: WJ12_13380
BPSL: WS57_32120
BSTG: WT74_14165
BGU: KS03_483
BGO: BM43_882
BUK: MYA_2429
BUL: BW21_3236
BPH: Bphy_0433
BFN: OI25_2110
PLG: NCTC10937_03311(dgoD)
BHZ: ACR54_00434(dgoD_1)
BTRM: SAMEA390648700632(dgoD)
AXX: ERS451415_05508(dgoD_2) ERS451415_05550(dgoD_3)
AMIM: MIM_c16930
ODI: ODI_R1140
RFR: Rfer_0951
AAV: Aave_2244
AAA: Acav_2896
VEI: Veis_3772
RTA: Rta_12390
CFU: CFU_3990(dgoA)
CARE: LT85_4542
AMIH: CO731_05357(dgoD_2)
SME: SM_b20510(dgoA)
SFD: USDA257_c25580(dgoD2) USDA257_c25590(dgoD3)
ARA: Arad_4061(dgoA)
REC: RHECIAT_CH0003971(dgoD)
RLE: RL3850(dgoD) RL3864 RL4233
SHZ: shn_23915
MMED: Mame_00554(dgoD_1) Mame_03669(dgoD_2) Mame_04784(dgoD_3) Mame_05151(dgoD_5)
PSF: PSE_1891
SAL: Sala_0742
SPHM: G432_09705
SPHI: TS85_03750
GDI: GDI2171(dgoD)
GDJ: Gdia_0390
BLI: BL03851(dgoA)
BLD: BLi04070(dgoD)
BLH: BaLi_c40790(dgoD)
BCL: ABC0524
BMQ: BMQ_3632
BMEG: BG04_582
BEO: BEH_11070
OIH: OB2215
GKA: GK1955
GTN: GTNG_1855
HHD: HBHAL_1500(dgoA)
PMS: KNP414_03157(dgoD)
LPAP: LBPC_2606
LRH: LGG_02664(dgoD)
LRG: LRHM_2558
EFN: DENG_00593(dgoD)
EFQ: DR75_2526
EDU: LIU_13690
CBE: Cbei_4845
CPAS: Clopa_0716
CPAT: CLPA_c05990(dgoD)
CPAE: CPAST_c05990(dgoD)
CACE: CACET_c06540(dgoD)
FPR: FP2_08870
THX: Thet_0163
TIT: Thit_0160
ROP: ROP_11630(dgoD)
SCO: SCO2401(SC4A7.29) SCO3475(SCE65.11c)
SFA: Sfla_4422
SVE: SVEN_6640
SALU: DC74_7970
SALL: SAZ_41150
STRE: GZL_06132
SLD: T261_5706
STRM: M444_35710
SPRI: SPRI_6597
SRW: TUE45_02989(dgoD)
SLE: sle_47980(sle_47980)
SNR: SNOUR_28420(dgoD)
STRD: NI25_27090
SALF: SMD44_07193(dgoD) SMD44_08481(dgoD)
SFK: KY5_6807c
ART: Arth_1901
ARM: ART_2463
ARX: ARZXY2_3635(dgoD)
AAI: AARI_31730(dgoD)
TFU: Tfu_1786
NDA: Ndas_1380
AMD: AMED_3144 AMED_7238(dgoA) AMED_9068(dgoA)
AMM: AMES_3110 AMES_7129(dgoA) AMES_8931(dgoA)
AMZ: B737_3111 B737_7129(dgoA) B737_8932(dgoA)
AOI: AORI_3001(dgoA)
AJA: AJAP_12740(dgoD)
PDX: Psed_0666
PSEE: FRP1_09865
AHG: AHOG_03740(dgoD1) AHOG_12630(dgoD2)
CAI: Caci_5013
SNA: Snas_0045
OLS: Olsu_0015
RCA: Rcas_3848
DGE: Dgeo_2811
DDR: Deide_1p01680(dgoD)
TTR: Tter_1664
CAA: Caka_0077
PLS: VT03_14730(dgoD_2)
PLH: VT85_16570(dgoD_1)
FMR: Fuma_05623(dgoD_2)
GES: VT84_25840(dgoD_3)
SACI: Sinac_2738
PBOR: BSF38_00594(dgoD)
ABAC: LuPra_00229(dgoD_1) LuPra_03167(dgoD_4)
GBA: J421_4308
FLN: FLA_2798
PHE: Phep_2597
FAE: FAES_4319
FLM: MY04_4319
CBAL: M667_09815
CBAT: M666_09805
AALG: AREALGSMS7_01368(dgoD)
TAC: Ta0756
TVO: TVG1250055(TVG1250055)
HHB: Hhub_2728(dgoD) Hhub_4020(gnaD)
HMA: pNG7031(dgoA1) rrnAC3069(dgoA3)
HMU: Hmuk_0122
HVO: HVO_A0331(dgoD1)
HME: HFX_5033
HLA: Hlac_2866
NAT: NJ7G_2709
STO: STK_25720(gnaD)
SSO: SSO2665
SOL: Ssol_0475
SSOA: SULA_0466
SSOL: SULB_0468
SSOF: SULC_0466
SID: M164_2634
SII: LD85_2966
SIH: SiH_2603
SIR: SiRe_2542
SIC: SiL_2491
AHO: Ahos_0325
CMA: Cmaq_0074
TUZ: TUZN_0966
 » show all
Taxonomy
Reference
1  [PMID:13462997]
  Authors
DE LEY J, DOUDOROFF M.
  Title
The metabolism of D-galactose in Pseudomonas saccharophila.
  Journal
J Biol Chem 227:745-57 (1957)
Reference
2  [PMID:422572]
  Authors
Donald A, Sibley D, Lyons DE, Dahms AS.
  Title
D-Galactonate dehydrase. Purification and properties.
  Journal
J Biol Chem 254:2132-7 (1979)
Other DBs
ExplorEnz - The Enzyme Database: 4.2.1.6
IUBMB Enzyme Nomenclature: 4.2.1.6
ExPASy - ENZYME nomenclature database: 4.2.1.6
BRENDA, the Enzyme Database: 4.2.1.6
CAS: 9024-38-8

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