KEGG   Gallus gallus (chicken): 426126
Entry
426126            CDS       T01006                                 
Symbol
MTHFD2
Name
(RefSeq) bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial
  KO
K13403  methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9]
Organism
gga  Gallus gallus (chicken)
Pathway
gga00670  One carbon pool by folate
gga01100  Metabolic pathways
gga01240  Biosynthesis of cofactors
Module
gga_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:gga00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    426126 (MTHFD2)
Enzymes [BR:gga01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.15  methylenetetrahydrofolate dehydrogenase (NAD+)
     426126 (MTHFD2)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     426126 (MTHFD2)
SSDB
Motif
Pfam: THF_DHG_CYH_C THF_DHG_CYH AlaDh_PNT_C PirA-like
Other DBs
NCBI-GeneID: 426126
NCBI-ProteinID: NP_001026531
CGNC: 52685
Ensembl: ENSGALG00000034344
UniProt: Q5ZKA5
Position
22:3867419..3873933
AA seq 337 aa
MATALCPLRALGQTAFRPRTRRLHLSAPRADAVVISGRKLARQIRQEARHEVEQWVAAGN
KRPHLSVVLVGENPASHSYVLNKTKAAADVGISSETILKPASITEEELLDLISKLNNDAN
VDGLLVQLPLPEHIDERKICNAVTPDKDVDGFHVINVGRMCLDQYSMLPATPWGVWEIIK
RTGIPTLGKNVVVAGRSKNVGMPIAMLLHTDGRHERPGGDATVTISHRYTPKEQLKQHTI
RADIVVAAAGIPNLITADMIKEGAAVIDVGITRVQDPITAKSRLVGDVDFEGVKKKASYI
TPVPGGVGPMTVAMLMKNTIIAAKKLLKPKALEALTA
NT seq 1014 nt   +upstreamnt  +downstreamnt
atggcaaccgcgctctgcccgctccgcgccctcggccagaccgctttccggccccgcacc
cgccgcctgcacctcagcgcacccagagctgatgcggttgtgatttctggaaggaagctg
gcccggcagatcagacaagaagcccgccatgaagttgaacagtgggtagcagctgggaac
aagagacctcacctcagcgtggttctggttggtgaaaatcctgcaagtcactcctatgtg
ctgaacaaaaccaaggcggctgctgatgtgggaatcagcagtgagacaatcctcaagcca
gcttcaattactgaggaggagctgctggatttgatcagcaaactaaataacgatgccaac
gtggatggcctgttagtgcagcttcccttaccagaacacattgacgagcggaagatttgc
aatgctgtgactccagacaaagatgttgatggctttcatgtgataaacgtggggcgcatg
tgccttgaccagtactccatgctgccagccaccccgtggggggtgtgggagatcataaag
agaacgggcatcccaacgctggggaagaacgtggtggtggccggccggtcgaagaatgtg
gggatgcccattgccatgctgctgcacacagatggcaggcacgagcgtccaggaggtgat
gccacggtaaccatatcacaccgctatactcccaaggagcagctgaaacaacacacgatc
cgtgctgacatcgtggtagcagcagcaggtattcctaatctgatcacagctgatatgatc
aaagaaggagctgcagttatcgatgtggggataactagagtgcaggatcctatcactgcc
aaatcaaggctggttggggatgtggattttgaaggggtgaagaagaaagccagttacatc
actccggtccctgggggagttgggcccatgacagttgccatgctgatgaagaacaccatc
attgctgccaagaagctgttgaaacccaaagcgctggaagccttaactgcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   CGNC (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (47)   

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