KEGG   Homo sapiens (human): 100528032
Entry
100528032         CDS       T01001                                 

Gene name
KLRC4-KLRK1
Definition
(RefSeq) KLRC4-KLRK1 readthrough
  KO
K06728  killer cell lectin-like receptor subfamily K member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa05144  Malaria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    100528032 (KLRC4-KLRK1)
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05144 Malaria
    100528032 (KLRC4-KLRK1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    100528032 (KLRC4-KLRK1)
   04091 Lectins [BR:hsa04091]
    100528032 (KLRC4-KLRK1)
CD molecules [BR:hsa04090]
 Proteins
  100528032 (KLRC4-KLRK1)
Lectins [BR:hsa04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   100528032 (KLRC4-KLRK1)
SSDB
Motif
Pfam: Lectin_C UL45 Chordopox_A33R
Other DBs
NCBI-GeneID: 100528032
NCBI-ProteinID: NP_001186734
HGNC: 48357
UniProt: P26718 A0A024RAP8
Structure
PDB: 
4PDC 4S0U 1MPU 1KCG 1HYR

Position
12p13.2
AA seq 216 aa
MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKSKCRENASPFFFCCFIA
VAMGIRFIIMVTIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFDESKNW
YESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLT
IIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV
NT seq 651 nt   +upstreamnt  +downstreamnt
atggggtggattcgtggtcggaggtctcgacacagctgggagatgagtgaatttcataat
tataacttggatctgaagaagagtgatttttcaacacgatggcaaaagcaaagatgtcca
gtagtcaaaagcaaatgtagagaaaatgcatctccattttttttctgctgcttcatcgct
gtagccatgggaatccgtttcattattatggtaacaatatggagtgctgtattcctaaac
tcattattcaaccaagaagttcaaattcccttgaccgaaagttactgtggcccatgtcct
aaaaactggatatgttacaaaaataactgctaccaattttttgatgagagtaaaaactgg
tatgagagccaggcttcttgtatgtctcaaaatgccagccttctgaaagtatacagcaaa
gaggaccaggatttacttaaactggtgaagtcatatcattggatgggactagtacacatt
ccaacaaatggatcttggcagtgggaagatggctccattctctcacccaacctactaaca
ataattgaaatgcagaagggagactgtgcactctatgcctcgagctttaaaggctatata
gaaaactgttcaactccaaatacgtacatctgcatgcaaaggactgtgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (3)   
   Pfam (3)   
All databases (38)   

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KEGG   Homo sapiens (human): 22914
Entry
22914             CDS       T01001                                 

Gene name
KLRK1, CD314, D12S2489E, KLR, NKG2-D, NKG2D
Definition
(RefSeq) killer cell lectin like receptor K1
  KO
K06728  killer cell lectin-like receptor subfamily K member 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04650  Natural killer cell mediated cytotoxicity
hsa05144  Malaria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    22914 (KLRK1)
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05144 Malaria
    22914 (KLRK1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    22914 (KLRK1)
   04091 Lectins [BR:hsa04091]
    22914 (KLRK1)
CD molecules [BR:hsa04090]
 Proteins
  22914 (KLRK1)
Lectins [BR:hsa04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   22914 (KLRK1)
SSDB
Motif
Pfam: Lectin_C UL45 Chordopox_A33R
Other DBs
NCBI-GeneID: 22914
NCBI-ProteinID: NP_031386
OMIM: 611817
HGNC: 18788
Ensembl: ENSG00000213809
Vega: OTTHUMG00000168574
Pharos: P26718(Tbio)
UniProt: P26718 A0A024RAP8
Structure
PDB: 
4PDC 4S0U 1MPU 1KCG 1HYR

Position
12p13.2
AA seq 216 aa
MGWIRGRRSRHSWEMSEFHNYNLDLKKSDFSTRWQKQRCPVVKSKCRENASPFFFCCFIA
VAMGIRFIIMVTIWSAVFLNSLFNQEVQIPLTESYCGPCPKNWICYKNNCYQFFDESKNW
YESQASCMSQNASLLKVYSKEDQDLLKLVKSYHWMGLVHIPTNGSWQWEDGSILSPNLLT
IIEMQKGDCALYASSFKGYIENCSTPNTYICMQRTV
NT seq 651 nt   +upstreamnt  +downstreamnt
atggggtggattcgtggtcggaggtctcgacacagctgggagatgagtgaatttcataat
tataacttggatctgaagaagagtgatttttcaacacgatggcaaaagcaaagatgtcca
gtagtcaaaagcaaatgtagagaaaatgcatctccattttttttctgctgcttcatcgct
gtagccatgggaatccgtttcattattatggtaacaatatggagtgctgtattcctaaac
tcattattcaaccaagaagttcaaattcccttgaccgaaagttactgtggcccatgtcct
aaaaactggatatgttacaaaaataactgctaccaattttttgatgagagtaaaaactgg
tatgagagccaggcttcttgtatgtctcaaaatgccagccttctgaaagtatacagcaaa
gaggaccaggatttacttaaactggtgaagtcatatcattggatgggactagtacacatt
ccaacaaatggatcttggcagtgggaagatggctccattctctcacccaacctactaaca
ataattgaaatgcagaagggagactgtgcactctatgcctcgagctttaaaggctatata
gaaaactgttcaactccaaatacgtacatctgcatgcaaaggactgtgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (3)   
   Pfam (3)   
All databases (49)   

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KEGG   Homo sapiens (human): 3820
Entry
3820              CDS       T01001                                 

Gene name
KLRB1, CD161, CLEC5B, NKR, NKR-P1, NKR-P1A, NKRP1A, hNKR-P1A
Definition
(RefSeq) killer cell lectin like receptor B1
  KO
K06543  killer cell lectin-like receptor subfamily B
Organism
hsa  Homo sapiens (human)
Pathway
hsa05144  Malaria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05144 Malaria
    3820 (KLRB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    3820 (KLRB1)
   04091 Lectins [BR:hsa04091]
    3820 (KLRB1)
CD molecules [BR:hsa04090]
 Proteins
  3820 (KLRB1)
Lectins [BR:hsa04091]
 C-Type lectins
  Gropu 5: NK-cell receptors
   3820 (KLRB1)
SSDB
Motif
Pfam: Lectin_C
Other DBs
NCBI-GeneID: 3820
NCBI-ProteinID: NP_002249
OMIM: 602890
HGNC: 6373
Ensembl: ENSG00000111796
Vega: OTTHUMG00000168581
Pharos: Q12918(Tbio)
UniProt: Q12918
Structure
PDB: 
5MGR 5MGS 5MGT

Position
12p13.31
AA seq 225 aa
MDQQAIYAELNLPTDSGPESSSPSSLPRDVCQGSPWHQFALKLSCAGIILLVLVVTGLSV
SVTSLIQKSSIEKCSVDIQQSRNKTTERPGLLNCPIYWQQLREKCLLFSHTVNPWNNSLA
DCSTKESSLLLIRDKDELIHTQNLIRDKAILFWIGLNFSLSEKNWKWINGSFLNSNDLEI
RGDAKENSCISISQTSVYSEYCSTEIRWICQKELTPVRNKVYPDS
NT seq 678 nt   +upstreamnt  +downstreamnt
atggaccaacaagcaatatatgctgagttaaacttacccacagactcaggcccagaaagt
tcttcaccttcatctcttcctcgggatgtctgtcagggttcaccttggcatcaatttgcc
ctgaaacttagctgtgctgggattattctccttgtcttggttgttactgggttgagtgtt
tcagtgacatccttaatacagaaatcatcaatagaaaaatgcagtgtggacattcaacag
agcaggaataaaacaacagagagaccgggtctcttaaactgcccaatatattggcagcaa
ctccgagagaaatgcttgttattttctcacactgtcaacccttggaataacagtctagct
gattgttccaccaaagaatccagcctgctgcttattcgagataaggatgaattgatacac
acacagaacctgatacgtgacaaagcaattctgttttggattggattaaatttttcatta
tcagaaaagaactggaagtggataaacggctcttttttaaattctaatgacttagaaatt
agaggtgatgctaaagaaaacagctgtatttccatctcacagacatctgtgtattctgag
tactgtagtacagaaatcagatggatctgccaaaaagaactaacacctgtgagaaataaa
gtgtatcctgactcttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (13)   
   RefSeq(nuc) (1)   
   GenBank (6)   
   EMBL (6)   
Protein domain (1)   
   Pfam (1)   
All databases (39)   

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