KEGG   Homo sapiens (human): 100533467
Entry
100533467         CDS       T01001                                 
Symbol
BIVM-ERCC5, ERCC5-202
Name
(RefSeq) BIVM-ERCC5 readthrough
  KO
K10846  DNA excision repair protein ERCC-5
Organism
hsa  Homo sapiens (human)
Pathway
hsa03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03420 Nucleotide excision repair
    100533467 (BIVM-ERCC5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    100533467 (BIVM-ERCC5)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    Other NER factors
     100533467 (BIVM-ERCC5)
SSDB
Motif
Pfam: XPG_I XPG_N 5_3_exonuc EF-G-binding_N
Other DBs
NCBI-GeneID: 100533467
NCBI-ProteinID: NP_001191354
HGNC: 43690
Ensembl: ENSG00000270181
UniProt: R4GMW8 Q59FZ7
Position
13:102807146..102875995
AA seq 1640 aa
MPNVAETERSNDSGNGEHKSERKSPEENLQGAVKSFCTSASGAPLGPKGDGHYPWSCPVT
HTREKIYAICSDYAFLNQATSIYKTPNPSRSPCLPDSTSLSAGNNSSRYIGIPTSTSEII
YNEENSLENLSNSLGKLPLAWEIDKSEFDGVTTNSKHKSGNAKKQVSKRKTSDKKGRYQK
ECPQHSPLEDIKQRKVLDLRRWYCISRPQYKTSCGISSLISCWNFLYSTMGAGNLPPITQ
EEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYKPHGKNKTAGET
ASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPLSPQEVEYWILI
GESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKKVGGNLHCIIAFQRL
NWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQHGRLGRSFSASFHQDSAWK
KMSNISIWLNQALKGVRDRHGNSIENPHLLTLFHRLCKLLFFRIRPIFVFDGDAPLLKKQ
TLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIKTAFRSKRDEALPSLTQVRRENDLYVL
PPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFFHNPQAIDIESEDFSSLPPEVKHEILT
DMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKKNYLNQHIEHVQKEMNQQHSGHIRRQY
EDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTVAEVDSESLPSSSKMHGMSFDVKSSPC
EKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEELESENRRQARGRNAPAAVDEGSISPR
TLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMRINSSTENSDEGLKVRDGKGIPFTATL
ASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVHVGTEAFPISDESMIKDRKDRLPLESA
VVRHSDAPGLPNGRELTPASPTCTNSVSKNETHAEVLEQQNELCPYESKFDSSLLSSDDE
TKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNVENVVSFNAKEHENFLETIQEQQTTES
AGQDLISIPKAVEPMEIDSEESESDGSFIEVQSVISDEELQAEFPETSKPPSEQGEEELV
GTREGEAPAESESLLRDNSERDDVDGEPQEAEKDAEDSLHEWQDINLEELETLESNLLAQ
QNSLKAQKQQQERIAATVTGQMFLESQELLRLFGIPYIQAPMEAEAQCAILDLTDQTSGT
ITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDFHNQLGLDRNKLINLAYLLGSDYTEGI
PTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQKNPKIRPNPHDTKVKKKLRTLQLTPG
FPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIREFCQRYFGWNRTKTDESLFPVLKQLDA
QQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVTCMLRKEKEAAASEIEAVSVAMEKEFE
LLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKGKNTCGGFLGETCLSESSDGSSSEDAE
SSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKNGGATTSSSSDSDDDGGKEKMVLVTAR
SVFGKKRRKLRRARGRKRKT
NT seq 4923 nt   +upstreamnt  +downstreamnt
atgcctaacgttgcagaaacagaaaggtcaaatgattctggaaatggtgagcacaaatct
gagagaaagtcacctgaagagaatctacaaggtgctgtaaaatctttctgcacaagtgcc
tcaggagcacccttgggtcccaaaggagatggtcattatccatggagttgtccagtgact
catacacgggaaaaaatttatgccatctgttcggactatgcctttctcaaccaggcgacc
tcaatctataaaactccaaatccatcccgctctccttgcctccctgatagtacctcttta
tctgctggaaataattcatcaagatacattggtatcccgactagtacatcggaaattatc
tacaatgaagaaaatagcttggaaaacttatccaacagcctgggcaagctacctctcgca
tgggaaattgataaatctgaatttgatggggtgaccacaaattcgaaacacaaatcaggc
aatgcaaagaaacaagtttccaagagaaaaacttcagataaaaagggaagatatcagaag
gaatgtcctcagcattctcctcttgaagatattaaacagcggaaagtattagacctcaga
cgatggtactgcataagccgaccacagtataagacttcttgtggcatctcttcattaatt
tcttgttggaatttcttatacagcacaatgggagctggaaaccttccacctattacccaa
gaagaagctttacatattctgggctttcaacctccatttgaagatattaggtttggtcct
ttcacggggaatacaacacttatgaggtggtttagacaaattaatgaccacttccatgta
aaaggatgctcttatgttctatataagcctcatgggaagaataaaacagcaggagaaact
gcttcaggggccctgtcaaagttaacccgtggattgaaagatgaatcgctggcttatatc
tatcattgccaaaatcattatttttgtccaattggcttcgaagcaacccctgttaaagct
aataaagcattcagcaggggacctctctcaccacaggaagttgaatattggatcttaatt
ggagaatcaagtagaaaacatcctgccattcactgtaaaaaatgggcagatattgttact
gatctaaacactcaaaatccagaatacctggatatccggcacttagagaggggactgcag
tatagaaaaacaaagaaggttgggggaaatttgcattgcatcatagcattccagagactt
aactggcaaagatttggcctttggaactttccatttggaaccattagacaagaatcacaa
cctccaacacatgcccagggaattgccaaatctgagagtgaagacaatatttccaagaag
cagcatgggcgtctgggccggtctttcagtgctagtttccatcaggactcggcatggaaa
aagatgtctaatattagcatttggttaaaccaagcacttaaaggagtccgggatcgccat
gggaactcaatagaaaatcctcatcttctcactttgtttcatcggctctgcaaactctta
ttttttcgaattcgtcctatttttgtgtttgatggggatgctccactattgaagaaacag
actttggtgaagagaaggcagagaaaggacttagcgtccagtgactccaggaaaacgaca
gagaagcttctgaaaacatttttgaaaagacaagccatcaaaactgccttcagaagcaaa
agagatgaagcactacccagtcttacccaagttcgaagagaaaacgacctctatgttttg
cctcctttacaagaggaagaaaaacacagttcagaagaggaagatgaaaaagaatggcaa
gaaagaatgaatcaaaaacaagcattacaggaagagttctttcataatcctcaagcgata
gatattgagtctgaggacttcagcagcctgccccctgaagtaaagcatgaaatcttgact
gatatgaaagagttcaccaagcgcagaagaacattatttgaagcaatgccagaggagtct
gatgacttttcacagtaccaactcaaaggcttgcttaaaaagaactatctgaaccagcat
atagaacatgtccaaaaggaaatgaatcagcaacattcaggacacatccgaaggcagtat
gaagatgaagggggctttctgaaggaggtagagtcaaggagagtggtctctgaagacact
tcacattacatcttgataaaaggtattcaagctaagacagttgcagaagtggattcagag
tctcttccttcttccagcaaaatgcacggcatgtcttttgacgtgaagtcatctccatgt
gaaaaactgaagacagagaaagagcctgatgctacccctccttctccaagaactttacta
gctatgcaagctgccctgctgggaagtagctcagaagaggagctggagagtgaaaatcga
aggcaggcccgtgggaggaacgcacctgctgctgtagacgaaggctccatatcaccccgg
actctttcagccattaagagagctcttgacgatgacgaagatgtaaaagtgtgtgctggg
gatgatgtgcagacgggagggccaggagcagaagaaatgcgtataaacagctccaccgag
aacagtgatgaaggacttaaagtgagagatggaaaaggaataccgtttactgcaacactt
gcgtcatctagtgtgaactctgcagaggagcacgtagccagcactaatgaggggagagag
cccacagactcagttccaaaagaacaaatgtcacttgttcacgtggggactgaagccttt
ccgataagtgatgagtctatgattaaggacagaaaagatcggctgcctctggagagtgca
gtggttagacatagtgacgcacctgggctcccgaatggaagggaactgacaccggcatct
ccaacttgtacaaattctgtgtcaaagaatgaaacacatgctgaagtgcttgagcagcag
aacgaactttgcccatatgagagtaaattcgattcttctcttctttcaagtgatgatgaa
acaaaatgtaaaccgaattctgcttctgaagtcattggccctgtcagtttgcaagaaaca
agtagcatagtaagtgtcccttcagaggcagtagataatgtggaaaatgtggtgtcattt
aatgctaaagagcatgagaattttctggaaaccatccaagaacagcagaccactgaatct
gcaggccaggatttaatttccattccaaaggccgtggaaccaatggaaattgactcggaa
gaaagtgaatctgatggaagtttcattgaagtgcaaagtgtgattagtgatgaggaactt
caagcagaattccctgaaacttccaaacctccctcagaacaaggcgaagaggaactggta
ggaactagggagggagaagcccctgctgagtccgagagcctcctgagggacaactctgag
agggacgacgtggatggtgagccacaggaagctgagaaagatgcggaagattcgctccat
gaatggcaagatattaatttggaggagttggaaactctggagagcaacctcttagcacag
cagaattcactgaaagctcaaaaacagcagcaagaacggatcgctgctactgtcaccgga
cagatgttcctggaaagccaggaactcctgcgcctgttcggcattccctacatccaggct
cccatggaagcagaggcgcagtgcgccatcctggacctgactgatcagacttccggaacc
atcactgatgacagtgatatctggctgtttggagcgcggcatgtctatagaaactttttt
aataaaaacaagtttgtagaatattatcaatatgtggactttcacaatcaattgggattg
gaccggaataagttaataaatttggcttatttgcttggaagtgattataccgaaggaata
ccaactgtgggttgtgtaaccgccatggaaattctcaatgaattccctgggcatggcctg
gaacctctcctaaaattctcagaatggtggcatgaagctcaaaaaaatccaaagataaga
cctaatcctcatgacaccaaagtgaaaaaaaaattacggacattgcaactcacccctggc
tttcctaacccagctgttgccgaggcctacctcaaacccgtggtggatgactcgaaggga
tcctttctgtgggggaaacctgatctcgacaaaattagagaattttgtcagcggtatttc
ggctggaacagaacgaagacagatgaatctctgtttcctgtattaaagcaactcgatgcc
cagcagacacagctccgaattgattccttctttagattagcacaacaggagaaagaagat
gctaaacgtattaagagccagagactaaacagagctgtgacatgtatgctaaggaaagag
aaagaagcagcagccagcgaaatagaagcagtttctgttgccatggagaaagaatttgag
ctacttgataaggcaaaaggaaaaacccagaagagaggcataacaaataccttagaagag
tcatcaagcctgaaaagaaagaggctttcagattctaaaggaaagaatacatgcggtgga
tttttgggggagacctgcctctcagaatcatctgatggatcttcaagtgaagatgctgaa
agttcatctttaatgaatgtacaaaggagaacagctgcgaaagagccaaaaaccagtgct
tcagattcgcagaactcagtgaaggaagctcccgtgaagaatggaggtgcgaccaccagc
agctctagtgatagtgatgacgatggagggaaagagaagatggtcctcgtgaccgccaga
tctgtgtttgggaagaaaagaaggaaactaagacgtgcgaggggaagaaaaaggaaaacc
taa

  All links  
Gene (24)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (2)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (4)   
   Pfam (4)   
All databases (36)   

Download RDF
KEGG   Homo sapiens (human): 2073
Entry
2073              CDS       T01001                                 
Symbol
ERCC5, COFS3, ERCC5-201, ERCM2, UVDR, XPG, XPGC
Name
(RefSeq) ERCC excision repair 5, endonuclease
  KO
K10846  DNA excision repair protein ERCC-5
Organism
hsa  Homo sapiens (human)
Pathway
hsa03420  Nucleotide excision repair
Network
nt06502  Nucleotide excision repair
  Element
N01431  Core NER reaction
Disease
H00076  Cockayne syndrome
H00403  Disorders of nucleotide excision repair
H01428  Xeroderma pigmentosum
H02570  Cerebro-oculo-facio-skeletal syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03420 Nucleotide excision repair
    2073 (ERCC5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:hsa03400]
    2073 (ERCC5)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    Other NER factors
     2073 (ERCC5)
SSDB
Motif
Pfam: XPG_N XPG_I 5_3_exonuc EF-G-binding_N
Other DBs
NCBI-GeneID: 2073
NCBI-ProteinID: NP_000114
OMIM: 133530
HGNC: 3437
Ensembl: ENSG00000134899
UniProt: P28715
Structure
Position
13:102846032..102875995
AA seq 1186 aa
MGVQGLWKLLECSGRQVSPEALEGKILAVDISIWLNQALKGVRDRHGNSIENPHLLTLFH
RLCKLLFFRIRPIFVFDGDAPLLKKQTLVKRRQRKDLASSDSRKTTEKLLKTFLKRQAIK
TAFRSKRDEALPSLTQVRRENDLYVLPPLQEEEKHSSEEEDEKEWQERMNQKQALQEEFF
HNPQAIDIESEDFSSLPPEVKHEILTDMKEFTKRRRTLFEAMPEESDDFSQYQLKGLLKK
NYLNQHIEHVQKEMNQQHSGHIRRQYEDEGGFLKEVESRRVVSEDTSHYILIKGIQAKTV
AEVDSESLPSSSKMHGMSFDVKSSPCEKLKTEKEPDATPPSPRTLLAMQAALLGSSSEEE
LESENRRQARGRNAPAAVDEGSISPRTLSAIKRALDDDEDVKVCAGDDVQTGGPGAEEMR
INSSTENSDEGLKVRDGKGIPFTATLASSSVNSAEEHVASTNEGREPTDSVPKEQMSLVH
VGTEAFPISDESMIKDRKDRLPLESAVVRHSDAPGLPNGRELTPASPTCTNSVSKNETHA
EVLEQQNELCPYESKFDSSLLSSDDETKCKPNSASEVIGPVSLQETSSIVSVPSEAVDNV
ENVVSFNAKEHENFLETIQEQQTTESAGQDLISIPKAVEPMEIDSEESESDGSFIEVQSV
ISDEELQAEFPETSKPPSEQGEEELVGTREGEAPAESESLLRDNSERDDVDGEPQEAEKD
AEDSLHEWQDINLEELETLESNLLAQQNSLKAQKQQQERIAATVTGQMFLESQELLRLFG
IPYIQAPMEAEAQCAILDLTDQTSGTITDDSDIWLFGARHVYRNFFNKNKFVEYYQYVDF
HNQLGLDRNKLINLAYLLGSDYTEGIPTVGCVTAMEILNEFPGHGLEPLLKFSEWWHEAQ
KNPKIRPNPHDTKVKKKLRTLQLTPGFPNPAVAEAYLKPVVDDSKGSFLWGKPDLDKIRE
FCQRYFGWNRTKTDESLFPVLKQLDAQQTQLRIDSFFRLAQQEKEDAKRIKSQRLNRAVT
CMLRKEKEAAASEIEAVSVAMEKEFELLDKAKGKTQKRGITNTLEESSSLKRKRLSDSKG
KNTCGGFLGETCLSESSDGSSSEDAESSSLMNVQRRTAAKEPKTSASDSQNSVKEAPVKN
GGATTSSSSDSDDDGGKEKMVLVTARSVFGKKRRKLRRARGRKRKT
NT seq 3561 nt   +upstreamnt  +downstreamnt
atgggggtccaggggctctggaagctgctggagtgctccgggcggcaggtcagccccgaa
gcgctggaagggaagatcctggctgttgatattagcatttggttaaaccaagcacttaaa
ggagtccgggatcgccatgggaactcaatagaaaatcctcatcttctcactttgtttcat
cggctctgcaaactcttattttttcgaattcgtcctatttttgtgtttgatggggatgct
ccactattgaagaaacagactttggtgaagagaaggcagagaaaggacttagcgtccagt
gactccaggaaaacgacagagaagcttctgaaaacatttttgaaaagacaagccatcaaa
actgccttcagaagcaaaagagatgaagcactacccagtcttacccaagttcgaagagaa
aacgacctctatgttttgcctcctttacaagaggaagaaaaacacagttcagaagaggaa
gatgaaaaagaatggcaagaaagaatgaatcaaaaacaagcattacaggaagagttcttt
cataatcctcaagcgatagatattgagtctgaggacttcagcagcctgccccctgaagta
aagcatgaaatcttgactgatatgaaagagttcaccaagcgcagaagaacattatttgaa
gcaatgccagaggagtctgatgacttttcacagtaccaactcaaaggcttgcttaaaaag
aactatctgaaccagcatatagaacatgtccaaaaggaaatgaatcagcaacattcagga
cacatccgaaggcagtatgaagatgaagggggctttctgaaggaggtagagtcaaggaga
gtggtctctgaagacacttcacattacatcttgataaaaggtattcaagctaagacagtt
gcagaagtggattcagagtctcttccttcttccagcaaaatgcacggcatgtcttttgac
gtgaagtcatctccatgtgaaaaactgaagacagagaaagagcctgatgctacccctcct
tctccaagaactttactagctatgcaagctgccctgctgggaagtagctcagaagaggag
ctggagagtgaaaatcgaaggcaggcccgtgggaggaacgcacctgctgctgtagacgaa
ggctccatatcaccccggactctttcagccattaagagagctcttgacgatgacgaagat
gtaaaagtgtgtgctggggatgatgtgcagacgggagggccaggagcagaagaaatgcgt
ataaacagctccaccgagaacagtgatgaaggacttaaagtgagagatggaaaaggaata
ccgtttactgcaacacttgcgtcatctagtgtgaactctgcagaggagcacgtagccagc
actaatgaggggagagagcccacagactcagttccaaaagaacaaatgtcacttgttcac
gtggggactgaagcctttccgataagtgatgagtctatgattaaggacagaaaagatcgg
ctgcctctggagagtgcagtggttagacatagtgacgcacctgggctcccgaatggaagg
gaactgacaccggcatctccaacttgtacaaattctgtgtcaaagaatgaaacacatgct
gaagtgcttgagcagcagaacgaactttgcccatatgagagtaaattcgattcttctctt
ctttcaagtgatgatgaaacaaaatgtaaaccgaattctgcttctgaagtcattggccct
gtcagtttgcaagaaacaagtagcatagtaagtgtcccttcagaggcagtagataatgtg
gaaaatgtggtgtcatttaatgctaaagagcatgagaattttctggaaaccatccaagaa
cagcagaccactgaatctgcaggccaggatttaatttccattccaaaggccgtggaacca
atggaaattgactcggaagaaagtgaatctgatggaagtttcattgaagtgcaaagtgtg
attagtgatgaggaacttcaagcagaattccctgaaacttccaaacctccctcagaacaa
ggcgaagaggaactggtaggaactagggagggagaagcccctgctgagtccgagagcctc
ctgagggacaactctgagagggacgacgtggatggtgagccacaggaagctgagaaagat
gcggaagattcgctccatgaatggcaagatattaatttggaggagttggaaactctggag
agcaacctcttagcacagcagaattcactgaaagctcaaaaacagcagcaagaacggatc
gctgctactgtcaccggacagatgttcctggaaagccaggaactcctgcgcctgttcggc
attccctacatccaggctcccatggaagcagaggcgcagtgcgccatcctggacctgact
gatcagacttccggaaccatcactgatgacagtgatatctggctgtttggagcgcggcat
gtctatagaaacttttttaataaaaacaagtttgtagaatattatcaatatgtggacttt
cacaatcaattgggattggaccggaataagttaataaatttggcttatttgcttggaagt
gattataccgaaggaataccaactgtgggttgtgtaaccgccatggaaattctcaatgaa
ttccctgggcatggcctggaacctctcctaaaattctcagaatggtggcatgaagctcaa
aaaaatccaaagataagacctaatcctcatgacaccaaagtgaaaaaaaaattacggaca
ttgcaactcacccctggctttcctaacccagctgttgccgaggcctacctcaaacccgtg
gtggatgactcgaagggatcctttctgtgggggaaacctgatctcgacaaaattagagaa
ttttgtcagcggtatttcggctggaacagaacgaagacagatgaatctctgtttcctgta
ttaaagcaactcgatgcccagcagacacagctccgaattgattccttctttagattagca
caacaggagaaagaagatgctaaacgtattaagagccagagactaaacagagctgtgaca
tgtatgctaaggaaagagaaagaagcagcagccagcgaaatagaagcagtttctgttgcc
atggagaaagaatttgagctacttgataaggcaaaaggaaaaacccagaagagaggcata
acaaataccttagaagagtcatcaagcctgaaaagaaagaggctttcagattctaaagga
aagaatacatgcggtggatttttgggggagacctgcctctcagaatcatctgatggatct
tcaagtgaagatgctgaaagttcatctttaatgaatgtacaaaggagaacagctgcgaaa
gagccaaaaaccagtgcttcagattcgcagaactcagtgaaggaagctcccgtgaagaat
ggaggtgcgaccaccagcagctctagtgatagtgatgacgatggagggaaagagaagatg
gtcctcgtgaccgccagatctgtgtttgggaagaaaagaaggaaactaagacgtgcgagg
ggaagaaaaaggaaaacctaa

  All links  
Disease (3)   
   OMIM (3)   
Gene (27)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (29)   
   RefSeq(nuc) (1)   
   GenBank (14)   
   EMBL (14)   
3D Structure (10)   
   PDB (10)   
Protein domain (4)   
   Pfam (4)   
All databases (76)   

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