KEGG   Homo sapiens (human): 10093
Entry
10093             CDS       T01001                                 
Symbol
ARPC4, ARC20, DEVLO, P20-ARC
Name
(RefSeq) actin related protein 2/3 complex subunit 4
  KO
K05755  actin related protein 2/3 complex, subunit 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04530  Tight junction
hsa04666  Fc gamma R-mediated phagocytosis
hsa04810  Regulation of actin cytoskeleton
hsa05100  Bacterial invasion of epithelial cells
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01078  EGF-EGFR-Actin signaling pathway
N01079  Shigella IpaC to Actin signaling pathway
N01086  Escherichia EspT to RAC signaling pathway
N01092  Escherichia Eae/Tir to Actin signaling pathway
N01094  Escherichia Eae/Tir/TccP to Actin signaling pathway
N01096  Escherichia Map to CDC42 signaling pathway
N01128  Salmonella SopE to RAC signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
N01287  Tight junction-Actin signaling pathway
Disease
H02685  Developmental delay with neuropsychiatric disorders
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10093 (ARPC4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    10093 (ARPC4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    10093 (ARPC4)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    10093 (ARPC4)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    10093 (ARPC4)
   05132 Salmonella infection
    10093 (ARPC4)
   05131 Shigellosis
    10093 (ARPC4)
   05135 Yersinia infection
    10093 (ARPC4)
   05100 Bacterial invasion of epithelial cells
    10093 (ARPC4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10093 (ARPC4)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    10093 (ARPC4)
Membrane trafficking [BR:hsa04131]
 Others
  Actin-binding proteins
   Arp2/3 complex
    10093 (ARPC4)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Arp2/3 complex
     10093 (ARPC4)
SSDB
Motif
Pfam: ARPC4 Sm_like Cmr7A DurN
Other DBs
NCBI-GeneID: 10093
NCBI-ProteinID: NP_005709
OMIM: 604226
HGNC: 707
Ensembl: ENSG00000241553
UniProt: P59998
Structure
Position
3:9792518..9807101
AA seq 168 aa
MTATLRPYLSAVRATLQAALCLENFSSQVVERHNKPEVEVRSSKELLLQPVTISRNEKEK
VLIEGSINSVRVSIAVKQADEIEKILCHKFMRFMMMRAENFFILRRKPVEGYDISFLITN
FHTEQMYKHKLVDFVIHFMEEIDKEISEMKLSVNARARIVAEEFLKNF
NT seq 507 nt   +upstreamnt  +downstreamnt
atgactgccactctccgcccctacctgagtgccgtgcgggccacattgcaggctgccctc
tgcctggagaacttctcctcccaggttgtggaacgacacaacaagccggaagtggaagtc
aggagtagcaaagagctcctgttacaacctgtgaccatcagcaggaatgagaaggaaaag
gttctgattgagggctccatcaactctgtccgggtcagcattgctgtgaaacaggctgat
gagatcgagaagattttgtgccacaagttcatgcgcttcatgatgatgcgagcagagaac
ttctttatccttcgaaggaagcctgtggaggggtatgatatcagctttctgatcaccaac
ttccacacagagcagatgtacaaacacaagttggtggactttgtgatccacttcatggag
gagattgacaaggagatcagtgagatgaagctgtcagtcaatgcccgtgcccgcattgtg
gctgaagagttccttaagaatttttaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (61)   
   RefGene (49)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (36)   
   RefSeq(nuc) (4)   
   GenBank (16)   
   EMBL (16)   
3D Structure (4)   
   PDB (4)   
Protein domain (4)   
   Pfam (4)   
All databases (113)   

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