KEGG   Homo sapiens (human): 10254
Entry
10254             CDS       T01001                                 
Symbol
STAM2, Hbp, STAM2A, STAM2B
Name
(RefSeq) signal transducing adaptor molecule 2
  KO
K04705  signal transducing adaptor molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    10254 (STAM2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    10254 (STAM2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    10254 (STAM2)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Endosomal sorting complexes required for transport (ESCRT)
   ESCRT-0 complex
    10254 (STAM2)
SSDB
Motif
Pfam: VHS SH3_1 SH3_9 SH3_2 UIM GAT ENTH UIM_2 SH3_10 HEAT_Maestro
Other DBs
NCBI-GeneID: 10254
NCBI-ProteinID: NP_005834
OMIM: 606244
HGNC: 11358
Ensembl: ENSG00000115145
UniProt: O75886
Structure
Position
2:complement(152116801..152175763)
AA seq 525 aa
MPLFTANPFEQDVEKATNEYNTTEDWSLIMDICDKVGSTPNGAKDCLKAIMKRVNHKVPH
VALQALTLLGACVANCGKIFHLEVCSRDFATEVRAVIKNKAHPKVCEKLKSLMVEWSEEF
QKDPQFSLISATIKSMKEEGITFPPAGSQTVSAAAKNGTSSNKNKEDEDIAKAIELSLQE
QKQQHTETKSLYPSSEIQLNNKVARKVRALYDFEAVEDNELTFKHGEIIIVLDDSDANWW
KGENHRGIGLFPSNFVTTNLNIETEAAAVDKLNVIDDDVEEIKKSEPEPVYIDEDKMDRA
LQVLQSIDPTDSKPDSQDLLDLEDICQQMGPMIDEKLEEIDRKHSELSELNVKVLEALEL
YNKLVNEAPVYSVYSKLHPPAHYPPASSGVPMQTYPVQSHGGNYMGQSIHQVTVAQSYSL
GPDQIGPLRSLPPNVNSSVTAQPAQTSYLSTGQDTVSNPTYMNQNSNLQSATGTTAYTQQ
MGMSVDMSSYQNTTSNLPQLAGFPVTVPAHPVAQQHTNYHQQPLL
NT seq 1578 nt   +upstreamnt  +downstreamnt
atgcctttgttcaccgccaaccccttcgagcaagacgtggaaaaagccacgaatgagtac
aacactacagaagattggagtcttattatggacatatgtgacaaagttggaagtactcct
aatggagcgaaagattgcctaaaagccataatgaaaagggtaaatcataaggttccacat
gttgctctgcaagcactaactcttcttggggcttgtgtggcaaactgtggaaagatattt
catttagaagtatgttcccgtgattttgcaacagaagtacgtgctgtgattaaaaataag
gcacatcctaaagtatgtgaaaaactgaaatctttaatggtggagtggtcagaagaattt
cagaaggaccctcagtttagtctgatatctgcaactattaaatctatgaaagaagaagga
attacttttcctccagcaggttctcagactgtctcagctgctgccaagaatggtacgtca
tcgaacaaaaacaaagaggatgaagacatagctaaagctattgaattatcgctgcaagaa
cagaaacagcaacacacagaaacaaaatccttatatccatcttcagaaattcagttaaat
aataaggttgcacggaaagtgagagctttatatgattttgaagctgttgaggacaatgaa
ctcacctttaaacatggtgaaataattattgttttggatgacagtgatgccaattggtgg
aaaggagaaaatcacagaggaataggacttttcccatccaattttgtaacaactaattta
aacatagagactgaggcagcggctgtggacaaattgaatgtaattgatgatgatgtggag
gaaattaagaaatcagagcctgagcctgtttatatagatgaggataagatggatagagcc
ctgcaggtacttcagagtatagatccaacagattcaaaaccagactcccaagaccttttg
gatttagaagatatctgccaacagatgggtccaatgatagatgaaaaacttgaagaaatt
gataggaagcattcagaattgtctgaattgaatgttaaagtcctggaagctctggaacta
tataacaaattggtgaatgaagcaccagtgtactcagtctattcaaagctccaccctcca
gcacattacccacctgcatcatctggggttccaatgcagacatatccagttcaatcacat
ggtggaaactatatgggtcagagcattcaccaagtaactgttgcccaaagctatagccta
ggacccgatcaaattggtccactgagatctctgcctccaaatgtgaattcctcagtgaca
gcacagcctgctcaaacttcatatttaagcactggacaagacactgtttccaatcctact
tatatgaaccagaactctaacctacagtcagctactggtacaactgcttacacacagcaa
atggggatgtctgtggatatgtcatcttatcagaacactacttccaatttgcctcaactg
gcaggctttccggtgacagttccagctcatccagttgcacagcagcacacaaattaccat
cagcagcctctcctttag

  All links  
Disease (1)   
   OMIM (1)   
Gene (7)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (25)   
   RefSeq(nuc) (1)   
   GenBank (12)   
   EMBL (12)   
3D Structure (5)   
   PDB (5)   
Protein domain (10)   
   Pfam (10)   
All databases (51)   

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KEGG   Homo sapiens (human): 8027
Entry
8027              CDS       T01001                                 
Symbol
STAM, STAM-1, STAM1
Name
(RefSeq) signal transducing adaptor molecule
  KO
K04705  signal transducing adaptor molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa04144  Endocytosis
hsa04630  JAK-STAT signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    8027 (STAM)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    8027 (STAM)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    8027 (STAM)
Membrane trafficking [BR:hsa04131]
 Endosome - Lysosome transport
  Endosomal sorting complexes required for transport (ESCRT)
   ESCRT-0 complex
    8027 (STAM)
SSDB
Motif
Pfam: VHS SH3_1 SH3_9 SH3_2 UIM GAT UIM_2 SH3_10
Other DBs
NCBI-GeneID: 8027
NCBI-ProteinID: NP_003464
OMIM: 601899
HGNC: 11357
Ensembl: ENSG00000136738
UniProt: Q92783
Structure
Position
10:17644151..17716824
AA seq 540 aa
MPLFATNPFDQDVEKATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPH
VAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVLNKGHPKVCEKLKALMVEWTDEFK
NDPQLSLISAMIKNLKEQGVTFPAIGSQAAEQAKASPALVAKDPGTVANKKEEEDLAKAI
ELSLKEQRQQSTTLSTLYPSTSSLLTNHQHEGRKVRAIYDFEAAEDNELTFKAGEIITVL
DDSDPNWWKGETHQGIGLFPSNFVTADLTAEPEMIKTEKKTVQFSDDVQVETIEPEPEPA
FIDEDKMDQLLQMLQSTDPSDDQPDLPELLHLEAMCHQMGPLIDEKLEDIDRKHSELSEL
NVKVMEALSLYTKLMNEDPMYSMYAKLQNQPYYMQSSGVSGSQVYAGPPPSGAYLVAGNA
QMSHLQSYSLPPEQLSSLSQAVVPPSANPALPSQQTQAAYPNTMVSSVQGNTYPSQAPVY
SPPPAATAAAATADVTLYQNAGPNMPQVPNYNLTSSTLPQPGGSQQPPQPQQPYSQKALL
NT seq 1623 nt   +upstreamnt  +downstreamnt
atgcctctttttgccaccaatcccttcgatcaggatgttgagaaagcaaccagcgagatg
aatactgctgaggactggggcctcattttggatatctgtgataaagttggtcagtctcgc
actggacctaaggattgtcttcggtctattatgagaagagtgaaccacaaagatcctcac
gttgctatgcaggctttgactcttctaggagcatgtgtatcaaactgtggcaaaattttt
catttagaagtatgttcaagagattttgctagtgaagtaagcaacgtattaaataagggt
catcctaaagtatgtgaaaaattaaaggctcttatggttgaatggacagatgaatttaag
aatgatccacagcttagtctaatatcagcaatgattaagaaccttaaggaacaaggagtt
acgttcccagctattggctctcaggctgcagaacaagcaaaagcaagcccagctcttgta
gccaaggatcctggtactgtggctaacaaaaaagaagaagaagatttagcaaaagccatt
gagttgtctctcaaggaacaaaggcagcagtcaaccaccctttccactttgtatccaagc
acatccagtctcttaactaaccaccaacatgaaggccgaaaagttcgtgctatatatgac
tttgaagctgctgaagacaatgaacttacttttaaagctggagaaattattacagttctt
gatgacagtgatcctaactggtggaaaggtgaaacccatcaaggcatagggttatttcct
tctaattttgtgactgcagatctcactgctgaaccagaaatgattaaaacagagaagaag
acggtacaatttagtgatgatgttcaggtagagacaatagaaccagagccggaaccagcc
tttattgatgaagataaaatggaccagttgctacagatgctgcaaagtacagaccccagt
gatgatcagccagacctaccagagctgcttcatcttgaagcaatgtgtcaccagatggga
cctctcattgatgaaaagctggaagatattgatagaaaacattcagaactctcagaactt
aatgtgaaagtgatggaggccctttccttatataccaagttaatgaacgaagatccgatg
tattccatgtatgcaaagttacagaatcagccatattatatgcagtcatctggtgtttct
ggttctcaggtgtatgcagggcctcctccaagtggtgcctacctggttgcagggaacgcg
cagatgagccacctccagagctacagtcttcccccggagcagctgtcttctctcagccag
gcagtggtcccaccatccgcaaacccagcccttcctagtcagcagactcaggccgcttac
ccaaatacaatggtcagttccgttcaaggaaacacatatcccagccaggcgccagtatat
agtcctcctcctgccgctactgctgctgctgcaactgccgatgtcactctgtaccagaat
gcaggacctaatatgccccaggtgccaaactataacttaacatcatcaactctgcctcag
cccggaggcagccaacagccacctcagccacagcaaccatattctcagaaggctctgcta
tag

  All links  
Disease (1)   
   OMIM (1)   
Gene (16)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (25)   
   RefSeq(nuc) (11)   
   GenBank (7)   
   EMBL (7)   
3D Structure (3)   
   PDB (3)   
Protein domain (8)   
   Pfam (8)   
All databases (66)   

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