KEGG   Homo sapiens (human): 1263Help
Entry
1263              CDS       T01001                                 

Gene name
PLK3, CNK, FNK, PLK-3, PRK
Definition
(RefSeq) polo like kinase 3
  KO
K08862  polo-like kinase 3 [EC:2.7.11.21]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04068  FoxO signaling pathway
hsa04625  C-type lectin receptor signaling pathway
hsa05152  Tuberculosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    1263 (PLK3)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    1263 (PLK3)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    1263 (PLK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1263 (PLK3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    1263 (PLK3)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    1263 (PLK3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.21  polo kinase
     1263 (PLK3)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  PLK family [OT]
   1263 (PLK3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Polo kinases
    1263 (PLK3)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    1263 (PLK3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr POLO_box Kinase-like Pkinase_fungal APH
Motif
Other DBs
NCBI-GeneID: 1263
NCBI-ProteinID: NP_004064
OMIM: 602913
HGNC: 2154
Ensembl: ENSG00000173846
Vega: OTTHUMG00000008491
Pharos: Q9H4B4(Tchem)
UniProt: Q9H4B4
Structure
PDB: 

Position
1p34.1
AA seq 646 aa AA seqDB search
MEPAAGFLSPRPFQRAAAAPAPPAGPGPPPSALRGPELEMLAGLPTSDPGRLITDPRSGR
TYLKGRLLGKGGFARCYEATDTETGSAYAVKVIPQSRVAKPHQREKILNEIELHRDLQHR
HIVRFSHHFEDADNIYIFLELCSRKSLAHIWKARHTLLEPEVRYYLRQILSGLKYLHQRG
ILHRDLKLGNFFITENMELKVGDFGLAARLEPPEQRKKTICGTPNYVAPEVLLRQGHGPE
ADVWSLGCVMYTLLCGSPPFETADLKETYRCIKQVHYTLPASLSLPARQLLAAILRASPR
DRPSIDQILRHDFFTKGYTPDRLPISSCVTVPDLTPPNPARSLFAKVTKSLFGRKKKSKN
HAQERDEVSGLVSGLMRTSVGHQDARPEAPAASGPAPVSLVETAPEDSSPRGTLASSGDG
FEEGLTVATVVESALCALRNCIAFMPPAEQNPAPLAQPEPLVWVSKWVDYSNKFGFGYQL
SSRRVAVLFNDGTHMALSANRKTVHYNPTSTKHFSFSVGAVPRALQPQLGILRYFASYME
QHLMKGGDLPSVEEVEVPAPPLLLQWVKTDQALLMLFSDGTVQVNFYGDHTKLILSGWEP
LLVTFVARNRSACTYLASHLRQLGCSPDLRQRLRYALRLLRDRSPA
NT seq 1941 nt NT seq  +upstreamnt  +downstreamnt
atggagcctgccgccggtttcctgtctccgcgccccttccagcgtgcggccgccgcgccc
gctcccccggccgggcccgggccgcctccgagtgccttgcgcggacctgagctggagatg
ctggccgggctaccgacgtcagaccccgggcgcctcatcacggacccgcgcagcggccgc
acctacctcaaaggccgcttgttgggcaaggggggcttcgcccgctgctacgaggccact
gacacagagactggcagcgcctacgctgtcaaagtcatcccgcagagccgcgtcgccaag
ccgcatcagcgcgagaagatcctaaatgagattgagctgcaccgagacctgcagcaccgc
cacatcgtgcgtttttcgcaccactttgaggacgctgacaacatctacattttcttggag
ctctgcagccgaaagtccctggcccacatctggaaggcccggcacaccctgttggagcca
gaagtgcgctactacctgcggcagatcctttctggcctcaagtacttgcaccagcgcggc
atcttgcaccgggacctcaagttgggaaattttttcatcactgagaacatggaactgaag
gtgggggattttgggctggcagcccggttggagcctccggagcagaggaagaagaccatc
tgtggcacccccaactatgtggctccagaagtgctgctgagacagggccacggccctgag
gcggatgtatggtcactgggctgtgtcatgtacacgctgctctgcgggagccctcccttt
gagacggctgacctgaaggagacgtaccgctgcatcaagcaggttcactacacgctgcct
gccagcctctcactgcctgcccggcagctcctggccgccatccttcgggcctcaccccga
gaccgcccctctattgaccagatcctgcgccatgacttctttaccaagggctacaccccc
gatcgactccctatcagcagctgcgtgacagtcccagacctgacaccccccaacccagct
aggagtctgtttgccaaagttaccaagagcctctttggcagaaagaagaagagtaagaat
catgcccaggagagggatgaggtctccggtttggtgagcggcctcatgcgcacatccgtt
ggccatcaggatgccaggccagaggctccagcagcttctggcccagcccctgtcagcctg
gtagagacagcacctgaagacagctcaccccgtgggacactggcaagcagtggagatgga
tttgaagaaggtctgactgtggccacagtagtggagtcagccctttgtgctctgagaaat
tgtatagccttcatgcccccagcggaacagaacccggcccccctggcccagccagagcct
ctggtgtgggtcagcaagtgggttgactactccaataagttcggctttgggtatcaactg
tccagccgccgtgtggctgtgctcttcaacgatggcacacatatggccctgtcggccaac
agaaagactgtgcactacaatcccaccagcacaaagcacttctccttctccgtgggtgct
gtgccccgggccctgcagcctcagctgggtatcctgcggtacttcgcctcctacatggag
cagcacctcatgaagggtggagatctgcccagtgtggaagaggtagaggtacctgctccg
cccttgctgctgcagtgggtcaagacggatcaggctctcctcatgctgtttagtgatggc
actgtccaggtgaacttctacggggaccacaccaagctgattctcagtggctgggagccc
ctccttgtgacttttgtggcccgaaatcgtagtgcttgtacttacctcgcttcccacctt
cggcagctgggctgctctccagacctgcggcagcgactccgctatgctctgcgcctgctc
cgggaccgcagcccagcctag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (22)   
   RefSeq(nuc) (2)   
   GenBank (10)   
   EMBL (10)   
Protein domain (6)   
   Pfam (6)   
All databases (57)   

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