KEGG   Homo sapiens (human): 1445
Entry
1445              CDS       T01001                                 

Gene name
CSK
Definition
(RefSeq) C-terminal Src kinase
  KO
K05728  c-src tyrosine kinase [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    1445 (CSK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1445 (CSK)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1445 (CSK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     1445 (CSK)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  CSK family
   1445 (CSK)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   1445 (CSK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 APH SH3_3
Other DBs
NCBI-GeneID: 1445
NCBI-ProteinID: NP_001120662
OMIM: 124095
HGNC: 2444
Ensembl: ENSG00000103653
Vega: OTTHUMG00000142814
Pharos: P41240(Tchem)
UniProt: P41240 B2R6Q4 A8K3B6
Structure
PDB: 

Position
15q24.1
AA seq 450 aa
MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII
PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV
SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ
DEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM
TQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE
AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE
KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK
NCWHLDAAMRPSFLQLREQLEHIKTHELHL
NT seq 1353 nt   +upstreamnt  +downstreamnt
atgtcagcaatacaggccgcctggccatccggtacagaatgtattgccaagtacaacttc
cacggcactgccgagcaggacctgcccttctgcaaaggagacgtgctcaccattgtggcc
gtcaccaaggaccccaactggtacaaagccaaaaacaaggtgggccgtgagggcatcatc
ccagccaactacgtccagaagcgggagggcgtgaaggcgggtaccaaactcagcctcatg
ccttggttccacggcaagatcacacgggagcaggctgagcggcttctgtacccgccggag
acaggcctgttcctggtgcgggagagcaccaactaccccggagactacacgctgtgcgtg
agctgcgacggcaaggtggagcactaccgcatcatgtaccatgccagcaagctcagcatc
gacgaggaggtgtactttgagaacctcatgcagctggtggagcactacacctcagacgca
gatggactctgtacgcgcctcattaaaccaaaggtcatggagggcacagtggcggcccag
gatgagttctaccgcagcggctgggccctgaacatgaaggagctgaagctgctgcagacc
atcgggaagggggagttcggagacgtgatgctgggcgattaccgagggaacaaagtcgcc
gtcaagtgcattaagaacgacgccactgcccaggccttcctggctgaagcctcagtcatg
acgcaactgcggcatagcaacctggtgcagctcctgggcgtgatcgtggaggagaagggc
gggctctacatcgtcactgagtacatggccaaggggagccttgtggactacctgcggtct
aggggtcggtcagtgctgggcggagactgtctcctcaagttctcgctagatgtctgcgag
gccatggaatacctggagggcaacaatttcgtgcatcgagacctggctgcccgcaatgtg
ctggtgtctgaggacaacgtggccaaggtcagcgactttggtctcaccaaggaggcgtcc
agcacccaggacacgggcaagctgccagtcaagtggacagcccctgaggccctgagagag
aagaaattctccactaagtctgacgtgtggagtttcggaatccttctctgggaaatctac
tcctttgggcgagtgccttatccaagaattcccctgaaggacgtcgtccctcgggtggag
aagggctacaagatggatgcccccgacggctgcccgcccgcagtctatgaagtcatgaag
aactgctggcacctggacgccgccatgcggccctccttcctacagctccgagagcagctt
gagcacatcaaaacccacgagctgcacctgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (17)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (50)   
   RefSeq(nuc) (14)   
   GenBank (18)   
   EMBL (18)   
Protein domain (8)   
   Pfam (8)   
All databases (94)   

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