KEGG   Homo sapiens (human): 1445
Entry
1445              CDS       T01001                                 
Symbol
CSK
Name
(RefSeq) C-terminal Src kinase
  KO
K05728  C-terminal Src kinase [EC:2.7.10.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05120  Epithelial cell signaling in Helicobacter pylori infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05120 Epithelial cell signaling in Helicobacter pylori infection
    1445 (CSK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1445 (CSK)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    1445 (CSK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.4  [Src-family] C-terminal protein kinase
     1445 (CSK)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  CSK family
   1445 (CSK)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   1445 (CSK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 ABC1 DUF7063
Other DBs
NCBI-GeneID: 1445
NCBI-ProteinID: NP_001120662
OMIM: 124095
HGNC: 2444
Ensembl: ENSG00000103653
UniProt: P41240 B2R6Q4 A8K3B6
Structure
Position
15:74782080..74803197
AA seq 450 aa
MSAIQAAWPSGTECIAKYNFHGTAEQDLPFCKGDVLTIVAVTKDPNWYKAKNKVGREGII
PANYVQKREGVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCV
SCDGKVEHYRIMYHASKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKPKVMEGTVAAQ
DEFYRSGWALNMKELKLLQTIGKGEFGDVMLGDYRGNKVAVKCIKNDATAQAFLAEASVM
TQLRHSNLVQLLGVIVEEKGGLYIVTEYMAKGSLVDYLRSRGRSVLGGDCLLKFSLDVCE
AMEYLEGNNFVHRDLAARNVLVSEDNVAKVSDFGLTKEASSTQDTGKLPVKWTAPEALRE
KKFSTKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPAVYEVMK
NCWHLDAAMRPSFLQLREQLEHIKTHELHL
NT seq 1353 nt   +upstreamnt  +downstreamnt
atgtcagcaatacaggccgcctggccatccggtacagaatgtattgccaagtacaacttc
cacggcactgccgagcaggacctgcccttctgcaaaggagacgtgctcaccattgtggcc
gtcaccaaggaccccaactggtacaaagccaaaaacaaggtgggccgtgagggcatcatc
ccagccaactacgtccagaagcgggagggcgtgaaggcgggtaccaaactcagcctcatg
ccttggttccacggcaagatcacacgggagcaggctgagcggcttctgtacccgccggag
acaggcctgttcctggtgcgggagagcaccaactaccccggagactacacgctgtgcgtg
agctgcgacggcaaggtggagcactaccgcatcatgtaccatgccagcaagctcagcatc
gacgaggaggtgtactttgagaacctcatgcagctggtggagcactacacctcagacgca
gatggactctgtacgcgcctcattaaaccaaaggtcatggagggcacagtggcggcccag
gatgagttctaccgcagcggctgggccctgaacatgaaggagctgaagctgctgcagacc
atcgggaagggggagttcggagacgtgatgctgggcgattaccgagggaacaaagtcgcc
gtcaagtgcattaagaacgacgccactgcccaggccttcctggctgaagcctcagtcatg
acgcaactgcggcatagcaacctggtgcagctcctgggcgtgatcgtggaggagaagggc
gggctctacatcgtcactgagtacatggccaaggggagccttgtggactacctgcggtct
aggggtcggtcagtgctgggcggagactgtctcctcaagttctcgctagatgtctgcgag
gccatggaatacctggagggcaacaatttcgtgcatcgagacctggctgcccgcaatgtg
ctggtgtctgaggacaacgtggccaaggtcagcgactttggtctcaccaaggaggcgtcc
agcacccaggacacgggcaagctgccagtcaagtggacagcccctgaggccctgagagag
aagaaattctccactaagtctgacgtgtggagtttcggaatccttctctgggaaatctac
tcctttgggcgagtgccttatccaagaattcccctgaaggacgtcgtccctcgggtggag
aagggctacaagatggatgcccccgacggctgcccgcccgcagtctatgaagtcatgaag
aactgctggcacctggacgccgccatgcggccctccttcctacagctccgagagcagctt
gagcacatcaaaacccacgagctgcacctgtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (8)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (17)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (50)   
   RefSeq(nuc) (14)   
   GenBank (18)   
   EMBL (18)   
3D Structure (6)   
   PDB (6)   
Protein domain (8)   
   Pfam (8)   
All databases (90)   

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