KEGG   Homo sapiens (human): 1969
Entry
1969              CDS       T01001                                 
Symbol
EPHA2, ARCC2, CTPA, CTPP1, CTRCT6, ECK
Name
(RefSeq) EPH receptor A2
  KO
K05103  Eph receptor A2 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
hsa04014  Ras signaling pathway
hsa04015  Rap1 signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04360  Axon guidance
Network
nt06526  MAPK signaling
nt06530  PI3K signaling
  Element
N01592  GF-RTK-RAS-ERK signaling pathway
N01599  Regulation of GF-RTK-RAS-ERK signaling, ubiquitination of RTK by CBL
N01656  GF-RTK-PI3K signaling pathway
N01658  GF-RTK-RAS-PI3K signaling pathway
Disease
H01202  Cataract
Drug target
Dasatinib (DG00714): D03658<JP> D06414<JP/US> D12609
Sitravatinib (DG03045): D11140 D11541
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    1969 (EPHA2)
   04014 Ras signaling pathway
    1969 (EPHA2)
   04015 Rap1 signaling pathway
    1969 (EPHA2)
   04151 PI3K-Akt signaling pathway
    1969 (EPHA2)
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    1969 (EPHA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    1969 (EPHA2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     1969 (EPHA2)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   1969 (EPHA2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_1 SAM_2 Pur_ac_phosph_N Ig_DSCAM-DSCAML_C Interfer-bind ABC1 Ephrin_rec_like Haspin_kinase CD34_antigen TM_ErbB1 Pkinase_fungal
Other DBs
NCBI-GeneID: 1969
NCBI-ProteinID: NP_004422
OMIM: 176946
HGNC: 3386
Ensembl: ENSG00000142627
UniProt: P29317
Structure
Position
1:complement(16124337..16156069)
AA seq 976 aa
MELQAARACFALLWGCALAAAAAAQGKEVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMN
DMPIYMYSVCNVMSGDQDNWLRTNWVYRGEAERIFIELKFTVRDCNSFPGGASSCKETFN
LYYAESDLDYGTNFQKRLFTKIDTIAPDEITVSSDFEARHVKLNVEERSVGPLTRKGFYL
AFQDIGACVALLSVRVYYKKCPELLQGLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGG
EEPRMHCAVDGEWLVPIGQCLCQAGYEKVEDACQACSPGFFKFEASESPCLECPEHTLPS
PEGATSCECEEGFFRAPQDPASMPCTRPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDI
VYSVTCEQCWPESGECGPCEASVRYSEPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSG
LVTSRSFRTASVSINQTEPPKVRLEGRSTTSLSVSWSIPPPQQSRVWKYEVTYRKKGDSN
SYNVRRTEGFSVTLDDLAPDTTYLVQVQALTQEGQGAGSKVHEFQTLSPEGSGNLAVIGG
VAVGVVLLLVLAGVGFFIHRRRKNQRARQSPEDVYFSKSEQLKPLKTYVDPHTYEDPNQA
VLKFTTEIHPSCVTRQKVIGAGEFGEVYKGMLKTSSGKKEVPVAIKTLKAGYTEKQRVDF
LGEAGIMGQFSHHNIIRLEGVISKYKPMMIITEYMENGALDKFLREKDGEFSVLQLVGML
RGIAAGMKYLANMNYVHRDLAARNILVNSNLVCKVSDFGLSRVLEDDPEATYTTSGGKIP
IRWTAPEAISYRKFTSASDVWSFGIVMWEVMTYGERPYWELSNHEVMKAINDGFRLPTPM
DCPSAIYQLMMQCWQQERARRPKFADIVSILDKLIRAPDSLKTLADFDPRVSIRLPSTSG
SEGVPFRTVSEWLESIKMQQYTEHFMAAGYTAIEKVVQMTNDDIKRIGVRLPGHQKRIAY
SLLGLKDQVNTVGIPI
NT seq 2931 nt   +upstreamnt  +downstreamnt
atggagctccaggcagcccgcgcctgcttcgccctgctgtggggctgtgcgctggccgcg
gccgcggcggcgcagggcaaggaagtggtactgctggactttgctgcagctggaggggag
ctcggctggctcacacacccgtatggcaaagggtgggacctgatgcagaacatcatgaat
gacatgccgatctacatgtactccgtgtgcaacgtgatgtctggcgaccaggacaactgg
ctccgcaccaactgggtgtaccgaggagaggctgagcgtatcttcattgagctcaagttt
actgtacgtgactgcaacagcttccctggtggcgccagctcctgcaaggagactttcaac
ctctactatgccgagtcggacctggactacggcaccaacttccagaagcgcctgttcacc
aagattgacaccattgcgcccgatgagatcaccgtcagcagcgacttcgaggcacgccac
gtgaagctgaacgtggaggagcgctccgtggggccgctcacccgcaaaggcttctacctg
gccttccaggatatcggtgcctgtgtggcgctgctctccgtccgtgtctactacaagaag
tgccccgagctgctgcagggcctggcccacttccctgagaccatcgccggctctgatgca
ccttccctggccactgtggccggcacctgtgtggaccatgccgtggtgccaccggggggt
gaagagccccgtatgcactgtgcagtggatggcgagtggctggtgcccattgggcagtgc
ctgtgccaggcaggctacgagaaggtggaggatgcctgccaggcctgctcgcctggattt
tttaagtttgaggcatctgagagcccctgcttggagtgccctgagcacacgctgccatcc
cctgagggtgccacctcctgcgagtgtgaggaaggcttcttccgggcacctcaggaccca
gcgtcgatgccttgcacacgacccccctccgccccacactacctcacagccgtgggcatg
ggtgccaaggtggagctgcgctggacgccccctcaggacagcgggggccgcgaggacatt
gtctacagcgtcacctgcgaacagtgctggcccgagtctggggaatgcgggccgtgtgag
gccagtgtgcgctactcggagcctcctcacggactgacccgcaccagtgtgacagtgagc
gacctggagccccacatgaactacaccttcaccgtggaggcccgcaatggcgtctcaggc
ctggtaaccagccgcagcttccgtactgccagtgtcagcatcaaccagacagagcccccc
aaggtgaggctggagggccgcagcaccacctcgcttagcgtctcctggagcatccccccg
ccgcagcagagccgagtgtggaagtacgaggtcacttaccgcaagaagggagactccaac
agctacaatgtgcgccgcaccgagggtttctccgtgaccctggacgacctggccccagac
accacctacctggtccaggtgcaggcactgacgcaggagggccagggggccggcagcaag
gtgcacgaattccagacgctgtccccggagggatctggcaacttggcggtgattggcggc
gtggctgtcggtgtggtcctgcttctggtgctggcaggagttggcttctttatccaccgc
aggaggaagaaccagcgtgcccgccagtccccggaggacgtttacttctccaagtcagaa
caactgaagcccctgaagacatacgtggacccccacacatatgaggaccccaaccaggct
gtgttgaagttcactaccgagatccatccatcctgtgtcactcggcagaaggtgatcgga
gcaggagagtttggggaggtgtacaagggcatgctgaagacatcctcggggaagaaggag
gtgccggtggccatcaagacgctgaaagccggctacacagagaagcagcgagtggacttc
ctcggcgaggccggcatcatgggccagttcagccaccacaacatcatccgcctagagggc
gtcatctccaaatacaagcccatgatgatcatcactgagtacatggagaatggggccctg
gacaagttccttcgggagaaggatggcgagttcagcgtgctgcagctggtgggcatgctg
cggggcatcgcagctggcatgaagtacctggccaacatgaactatgtgcaccgtgacctg
gctgcccgcaacatcctcgtcaacagcaacctggtctgcaaggtgtctgactttggcctg
tcccgcgtgctggaggacgaccccgaggccacctacaccaccagtggcggcaagatcccc
atccgctggaccgccccggaggccatttcctaccggaagttcacctctgccagcgacgtg
tggagctttggcattgtcatgtgggaggtgatgacctatggcgagcggccctactgggag
ttgtccaaccacgaggtgatgaaagccatcaatgatggcttccggctccccacacccatg
gactgcccctccgccatctaccagctcatgatgcagtgctggcagcaggagcgtgcccgc
cgccccaagttcgctgacatcgtcagcatcctggacaagctcattcgtgcccctgactcc
ctcaagaccctggctgactttgacccccgcgtgtctatccggctccccagcacgagcggc
tcggagggggtgcccttccgcacggtgtccgagtggctggagtccatcaagatgcagcag
tatacggagcacttcatggcggccggctacactgccatcgagaaggtggtgcagatgacc
aacgacgacatcaagaggattggggtgcggctgcccggccaccagaagcgcatcgcctac
agcctgctgggactcaaggaccaggtgaacactgtggggatccccatctga

  All links  
Disease (2)   
   OMIM (2)   
Gene (19)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (26)   
   RefSeq(nuc) (10)   
   GenBank (8)   
   EMBL (8)   
3D Structure (103)   
   PDB (103)   
Protein domain (16)   
   Pfam (16)   
All databases (178)   

Download RDF
KEGG   Homo sapiens (human): 2041
Entry
2041              CDS       T01001                                 
Symbol
EPHA1, EPH, EPHT, EPHT1
Name
(RefSeq) EPH receptor A1
  KO
K05102  Eph receptor A1 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Drug target
Sitravatinib (DG03045): D11140 D11541
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2041 (EPHA1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2041 (EPHA1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2041 (EPHA1)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2041 (EPHA1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase SAM_1 fn3 EphA2_TM SAM_2 Pur_ac_phosph_N Ephrin_rec_like ABC1 Tissue_fac Haspin_kinase Kdo SAM_CEP-1_C
Other DBs
NCBI-GeneID: 2041
NCBI-ProteinID: NP_005223
OMIM: 179610
HGNC: 3385
Ensembl: ENSG00000146904
UniProt: P21709
Structure
Position
7:complement(143391129..143408856)
AA seq 976 aa
MERRWPLGLGLVLLLCAPLPPGARAKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQILNG
TPLYMYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKE
TFNLLYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRG
LYLAFHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLPGPAGLVEVAGTCLPHARASPR
PSGAPRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQ
STAESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGG
RQDVRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVE
AQNGVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSPGANLT
YELHVLNQDEERYQMVLEPRVLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSPPVS
RGLTGGEIVAVIFGLLLGAALLLGILVFRSRRAQRQRQQRQRDRATDVDREDKLWLKPYV
DLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKD
TSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQ
LVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGT
YETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIE
DGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRM
TLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITL
PGHQKRILCSIQGFKD
NT seq 2931 nt   +upstreamnt  +downstreamnt
atggagcggcgctggcccctggggctagggctggtgctgctgctctgcgccccgctgccc
ccgggggcgcgcgccaaggaagttactctgatggacacaagcaaggcacagggagagctg
ggctggctgctggatcccccaaaagatgggtggagtgaacagcaacagatactgaatggg
acacccctgtacatgtaccaggactgcccaatgcaaggacgcagagacactgaccactgg
cttcgctccaattggatctaccgcggggaggaggcttcccgcgtccacgtggagctgcag
ttcaccgtgcgggactgcaagagtttccctgggggagccgggcctctgggctgcaaggag
accttcaaccttctgtacatggagagtgaccaggatgtgggcattcagctccgacggccc
ttgttccagaaggtaaccacggtggctgcagaccagagcttcaccattcgagaccttgtg
tctggctccgtgaagctgaatgtggagcgctgctctctgggccgcctgacccgccgtggc
ctctacctcgctttccacaacccgggtgcctgtgtggccctggtgtctgtccgggtcttc
taccagcgctgtcctgagaccctgaatggcttggcccaattcccagacactctgcctggc
cccgctgggttggtggaagtggcggggacctgcttgccccacgcgcgggccagccccagg
ccctcaggtgcaccccgcatgcactgcagccctgatggcgagtggctggtgcctgtagga
cggtgccactgtgagcctggctatgaggaaggtggcagtggcgaagcatgtgttgcctgc
cctagcggctcctaccggatggacatggacacaccccattgtctcacgtgcccccagcag
agcactgctgagtctgagggggccaccatctgtacctgtgagagcggccattacagagct
cccggggagggcccccaggtggcatgcacaggtcccccctcggccccccgaaacctgagc
ttctctgcctcagggactcagctctccctgcgttgggaacccccagcagatacgggggga
cgccaggatgtcagatacagtgtgaggtgttcccagtgtcagggcacagcacaggacggg
gggccctgccagccctgtggggtgggcgtgcacttctcgccgggggcccgggggctcacc
acacctgcagtgcatgtcaatggccttgaaccttatgccaactacacctttaatgtggaa
gcccaaaatggagtgtcagggctgggcagctctggccatgccagcacctcagtcagcatc
agcatggggcatgcagagtcactgtcaggcctgtctctgagactggtgaagaaagaaccg
aggcaactagagctgacctgggcggggtcccggccccgaagccctggggcgaacctgacc
tatgagctgcacgtgctgaaccaggatgaagaacggtaccagatggttctagaacccagg
gtcttgctgacagagctgcagcctgacaccacatacatcgtcagagtccgaatgctgacc
ccactgggtcctggccctttctcccctgatcatgagtttcggaccagcccaccagtgtcc
aggggcctgactggaggagagattgtagccgtcatctttgggctgctgcttggtgcagcc
ttgctgcttgggattctcgttttccggtccaggagagcccagcggcagaggcagcagagg
cagcgtgaccgcgccaccgatgtggatcgagaggacaagctgtggctgaagccttatgtg
gacctccaggcatacgaggaccctgcacagggagccctggactttacccgggagcttgat
ccagcgtggctgatggtggacactgtcataggagaaggagagtttggggaagtgtatcga
gggaccctgaggctccccagccaggactgcaagactgtggccattaagaccttaaaagac
acatccccaggtggccagtggtggaacttccttcgagaggcaactatcatgggccagttt
agccacccgcatattctgcatctggaaggcgtcgtcacaaagcgaaagccgatcatgatc
atcacagaatttatggagaatggagccctggatgccttcctgagggagcgggaggaccag
ctggtccctgggcagctagtggccatgctgcagggcatagcatctggcatgaactacctc
agtaatcacaattatgtccaccgggacctggctgccagaaacatcttggtgaatcaaaac
ctgtgctgcaaggtgtctgactttggcctgactcgcctcctggatgactttgatggcaca
tacgaaacccagggaggaaagatccctatccgttggacagcccctgaagccattgcccat
cggatcttcaccacagccagcgatgtgtggagctttgggattgtgatgtgggaggtgctg
agctttggggacaagccttatggggagatgagcaatcaggaggttatgaagagcattgag
gatgggtaccggttgccccctcctgtggactgccctgcccctctgtatgagctcatgaag
aactgctgggcatatgaccgtgcccgccggccacacttccagaagcttcaggcacatctg
gagcaactgcttgccaacccccactccctgcggaccattgccaactttgaccccaggatg
actcttcgcctgcccagcctgagtggctcagatgggatcccatatcgaaccgtctctgag
tggctcgagtccatacgcatgaaacgctacatcctgcacttccactcggctgggctggac
accatggagtgtgtgctggagctgaccgctgaggacctgacgcagatgggaatcacactg
cccgggcaccagaagcgcattctttgcagtattcagggattcaaggactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (21)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (33)   
   RefSeq(nuc) (1)   
   GenBank (16)   
   EMBL (16)   
3D Structure (4)   
   PDB (4)   
Protein domain (14)   
   Pfam (14)   
All databases (76)   

Download RDF
KEGG   Homo sapiens (human): 2042
Entry
2042              CDS       T01001                                 
Symbol
EPHA3, EK4, ETK, ETK1, HEK, HEK4, TYRO4
Name
(RefSeq) EPH receptor A3
  KO
K05104  Eph receptor A3 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2042 (EPHA3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2042 (EPHA3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2042 (EPHA3)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2042 (EPHA3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_2 SAM_1 Pur_ac_phosph_N Ephrin_rec_like Ig_DSCAM-DSCAML_C CRLF2-like_D2 ABC1 fn3_2 Kdo SusE Haspin_kinase Pkinase_fungal TMEM154 EssA
Other DBs
NCBI-GeneID: 2042
NCBI-ProteinID: NP_005224
OMIM: 179611
HGNC: 3387
Ensembl: ENSG00000044524
UniProt: P29320 A0A140VJJ0 Q6P4R6
Structure
Position
3:89107621..89482134
AA seq 983 aa
MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE
HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF
NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY
LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP
RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG
SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN
IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS
PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ
ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESS
QVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPH
TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT
EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV
IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT
TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG
YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSN
LLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG
PQKKIISSIKALETQSKNGPVPV
NT seq 2952 nt   +upstreamnt  +downstreamnt
atggattgtcagctctccatcctcctccttctcagctgctctgttctcgacagcttcggg
gaactgattccgcagccttccaatgaagtcaatctactggattcaaaaacaattcaaggg
gagctgggctggatctcttatccatcacatgggtgggaagagatcagtggtgtggatgaa
cattacacacccatcaggacttaccaggtgtgcaatgtcatggaccacagtcaaaacaat
tggctgagaacaaactgggtccccaggaactcagctcagaagatttatgtggagctcaag
ttcactctacgagactgcaatagcattccattggttttaggaacttgcaaggagacattc
aacctgtactacatggagtctgatgatgatcatggggtgaaatttcgagagcatcagttt
acaaagattgacaccattgcagctgatgaaagtttcactcaaatggatcttggggaccgt
attctgaagctcaacactgagattagagaagtaggtcctgtcaacaagaagggattttat
ttggcatttcaagatgttggtgcttgtgttgccttggtgtctgtgagagtatacttcaaa
aagtgcccatttacagtgaagaatctggctatgtttccagacacggtacccatggactcc
cagtccctggtggaggttagagggtcttgtgtcaacaattctaaggaggaagatcctcca
aggatgtactgcagtacagaaggcgaatggcttgtacccattggcaagtgttcctgcaat
gctggctatgaagaaagaggttttatgtgccaagcttgtcgaccaggtttctacaaggca
ttggatggtaatatgaagtgtgctaagtgcccgcctcacagttctactcaggaagatggt
tcaatgaactgcaggtgtgagaataattacttccgggcagacaaagaccctccatccatg
gcttgtacccgacctccatcttcaccaagaaatgttatctctaatataaacgagacctca
gttatcctggactggagttggcccctggacacaggaggccggaaagatgttaccttcaac
atcatatgtaaaaaatgtgggtggaatataaaacagtgtgagccatgcagcccaaatgtc
cgcttcctccctcgacagtttggactcaccaacaccacggtgacagtgacagaccttctg
gcacatactaactacacctttgagattgatgccgttaatggggtgtcagagctgagctcc
ccaccaagacagtttgctgcggtcagcatcacaactaatcaggctgctccatcacctgtc
ctgacgattaagaaagatcggacctccagaaatagcatctctttgtcctggcaagaacct
gaacatcctaatgggatcatattggactacgaggtcaaatactatgaaaagcaggaacaa
gaaacaagttataccattctgagggcaagaggcacaaatgttaccatcagtagcctcaag
cctgacactatatacgtattccaaatccgagcccgaacagccgctggatatgggacgaac
agccgcaagtttgagtttgaaactagtccagactctttctccatctctggtgaaagtagc
caagtggtcatgatcgccatttcagcggcagtagcaattattctcctcactgttgtcatc
tatgttttgattgggaggttctgtggctataagtcaaaacatggggcagatgaaaaaaga
cttcattttggcaatgggcatttaaaacttccaggtctcaggacttatgttgacccacat
acatatgaagaccctacccaagctgttcatgagtttgccaaggaattggatgccaccaac
atatccattgataaagttgttggagcaggtgaatttggagaggtgtgcagtggtcgctta
aaacttccttcaaaaaaagagatttcagtggccattaagaccctgaaagttggctacaca
gaaaagcagaggagagacttcctgggagaagcaagcattatgggacagtttgaccacccc
aatatcattcgactggaaggagttgttaccaaaagtaagccagttatgattgtcacagaa
tacatggagaatggttccttggatagtttcctacgtaaacacgatgcccagtttactgtc
attcagctagtggggatgcttcgagggatagcatctggcatgaagtacctgtcagacatg
ggctatgttcaccgagacctcgctgctcggaacatcttgatcaacagtaacttggtgtgt
aaggtttctgatttcggactttcgcgtgtcctggaggatgacccagaagctgcttataca
acaagaggagggaagatcccaatcaggtggacatcaccagaagctatagcctaccgcaag
ttcacgtcagccagcgatgtatggagttatgggattgttctctgggaggtgatgtcttat
ggagagagaccatactgggagatgtccaatcaggatgtaattaaagctgtagatgagggc
tatcgactgccaccccccatggactgcccagctgccttgtatcagctgatgctggactgc
tggcagaaagacaggaacaacagacccaagtttgagcagattgttagtattctggacaag
cttatccggaatcccggcagcctgaagatcatcaccagtgcagccgcaaggccatcaaac
cttcttctggaccaaagcaatgtggatatcactaccttccgcacaacaggtgactggctt
aatggtgtctggacagcacactgcaaggaaatcttcacgggtgtggagtacagttcttgt
gacacaatagccaagatttccacagatgacatgaaaaaggttggtgtcaccgtggttggg
ccacagaagaagatcatcagtagcattaaagctctagaaacgcaatcaaagaatggccca
gttcccgtgtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (12)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (11)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (25)   
   RefSeq(nuc) (7)   
   GenBank (9)   
   EMBL (9)   
3D Structure (28)   
   PDB (28)   
Protein domain (19)   
   Pfam (19)   
All databases (96)   

Download RDF
KEGG   Homo sapiens (human): 2043
Entry
2043              CDS       T01001                                 
Symbol
EPHA4, EK8, HEK8, SEK, TYRO1
Name
(RefSeq) EPH receptor A4
  KO
K05105  Eph receptor A4 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Network
nt06511  NOTCH signaling
  Element
N01481  Notch-MESP2 signaling
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2043 (EPHA4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2043 (EPHA4)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2043 (EPHA4)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2043 (EPHA4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_2 SAM_1 Pur_ac_phosph_N Ig_DSCAM-DSCAML_C Ephrin_rec_like fn3_2 CRLF2-like_D2 ABC1 Haspin_kinase Kdo DUF6377
Other DBs
NCBI-GeneID: 2043
NCBI-ProteinID: NP_001291465
OMIM: 602188
HGNC: 3388
Ensembl: ENSG00000116106
UniProt: P54764
Structure
Position
2:complement(221418027..221574202)
AA seq 986 aa
MAGIFYFALFSCLFGICDAVTGSRVYPANEVTLLDSRSVQGELGWIASPLEGGWEEVSIM
DEKNTPIRTYQVCNVMEPSQNNWLRTDWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKE
TFNLYYYESDNDKERFIRENQFVKIDTIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKG
FYLAFQDVGACIALVSVRVFYKKCPLTVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEK
DVPKMYCGADGEWLVPIGNCLCNAGHEERSGECQACKIGYYKALSTDATCAKCPPHSYSV
WEGATSCTCDRGFFRADNDAASMPCTRPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDI
SYNVVCKKCGAGDPSKCRPCGSGVHYTPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVS
KYNPNPDQSVSVTVTTNQAAPSSIALVQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYE
KDQNERSYRIVRTAARNTDIKGLNPLTSYVFHVRARTAAGYGDFSEPLEVTTNTVPSRII
GDGANSTVLLVSVSGSVVLVVILIAAFVISRRRSKYSKAKQEADEEKHLNQGVRTYVDPF
TYEDPNQAVREFAKEIDASCIKIEKVIGVGEFGEVCSGRLKVPGKREICVAIKTLKAGYT
DKQRRDFLSEASIMGQFDHPNIIHLEGVVTKCKPVMIITEYMENGSLDAFLRKNDGRFTV
IQLVGMLRGIGSGMKYLSDMSYVHRDLAARNILVNSNLVCKVSDFGMSRVLEDDPEAAYT
TRGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEG
YRLPPPMDCPIALHQLMLDCWQKERSDRPKFGQIVNMLDKLIRNPNSLKRTGTESSRPNT
ALLDPSSPEFSAVVSVGDWLQAIKMDRYKDNFTAAGYTTLEAVVHVNQEDLARIGITAIT
HQNKILSSVQAMRTQMQQMHGRMVPV
NT seq 2961 nt   +upstreamnt  +downstreamnt
atggctgggattttctatttcgccctattttcgtgtctcttcgggatttgcgacgctgtc
acaggttccagggtataccccgcgaatgaagttaccttattggattccagatctgttcag
ggagaacttgggtggatagcaagccctctggaaggagggtgggaggaagtgagtatcatg
gatgaaaaaaatacaccaatccgaacctaccaagtgtgcaatgtgatggaacccagccag
aataactggctacgaactgattggatcacccgagaaggggctcagagggtgtatattgag
attaaattcaccttgagggactgcaatagtcttccgggcgtcatggggacttgcaaggag
acgtttaacctgtactactatgaatcagacaacgacaaagagcgtttcatcagagagaac
cagtttgtcaaaattgacaccattgctgctgatgagagcttcacccaagtggacattggt
gacagaatcatgaagctgaacaccgagatccgggatgtagggccattaagcaaaaagggg
ttttacctggcttttcaggatgtgggggcctgcatcgccctggtatcagtccgtgtgttc
tataaaaagtgtccactcacagtccgcaatctggcccagtttcctgacaccatcacaggg
gctgatacgtcttccctggtggaagttcgaggctcctgtgtcaacaactcagaagagaaa
gatgtgccaaaaatgtactgtggggcagatggtgaatggctggtacccattggcaactgc
ctatgcaacgctgggcatgaggagcggagcggagaatgccaagcttgcaaaattggatat
tacaaggctctctccacggatgccacctgtgccaagtgcccaccccacagctactctgtc
tgggaaggagccacctcgtgcacctgtgaccgaggctttttcagagctgacaacgatgct
gcctctatgccctgcacccgtccaccatctgctcccctgaacttgatttcaaatgtcaac
gagacatctgtgaacttggaatggagtagccctcagaatacaggtggccgccaggacatt
tcctataatgtggtatgcaagaaatgtggagctggtgaccccagcaagtgccgaccctgt
ggaagtggggtccactacaccccacagcagaatggcttgaagaccaccaaagtctccatc
actgacctcctagctcataccaattacacctttgaaatctgggctgtgaatggagtgtcc
aaatataaccctaacccagaccaatcagtttctgtcactgtgaccaccaaccaagcagca
ccatcatccattgctttggtccaggctaaagaagtcacaagatacagtgtggcactggct
tggctggaaccagatcggcccaatggggtaatcctggaatatgaagtcaagtattatgag
aaggatcagaatgagcgaagctatcgtatagttcggacagctgccaggaacacagatatc
aaaggcctgaaccctctcacttcctatgttttccacgtgcgagccaggacagcagctggc
tatggagacttcagtgagcccttggaggttacaaccaacacagtgccttcccggatcatt
ggagatggggctaactccacagtccttctggtctctgtctcgggcagtgtggtgctggtg
gtaattctcattgcagcttttgtcatcagccggagacggagtaaatacagtaaagccaaa
caagaagcggatgaagagaaacatttgaatcaaggtgtaagaacatatgtggaccccttt
acgtacgaagatcccaaccaagcagtgcgagagtttgccaaagaaattgacgcatcctgc
attaagattgaaaaagttataggagttggtgaatttggtgaggtatgcagtgggcgtctc
aaagtgcctggcaagagagagatctgtgtggctatcaagactctgaaagctggttataca
gacaaacagaggagagacttcctgagtgaggccagcatcatgggacagtttgaccatccg
aacatcattcacttggaaggcgtggtcactaaatgtaaaccagtaatgatcataacagag
tacatggagaatggctccttggatgcattcctcaggaaaaatgatggcagatttacagtc
attcagctggtgggcatgcttcgtggcattgggtctgggatgaagtatttatctgatatg
agctatgtgcatcgtgatctggccgcacggaacatcctggtgaacagcaacttggtctgc
aaagtgtctgattttggcatgtcccgagtgcttgaggatgatccggaagcagcttacacc
accaggggtggcaagattcctatccggtggactgcgccagaagcaattgcctatcgtaaa
ttcacatcagcaagtgatgtatggagctatggaatcgttatgtgggaagtgatgtcgtac
ggggagaggccctattgggatatgtccaatcaagatgtgattaaagccattgaggaaggc
tatcggttaccccctccaatggactgccccattgcgctccaccagctgatgctagactgc
tggcagaaggagaggagcgacaggcctaaatttgggcagattgtcaacatgttggacaaa
ctcatccgcaaccccaacagcttgaagaggacagggacggagagctccagacctaacact
gccttgttggatccaagctcccctgaattctctgctgtggtatcagtgggcgattggctc
caggccattaaaatggaccggtataaggataacttcacagctgctggttataccacacta
gaggctgtggtgcacgtgaaccaggaggacctggcaagaattggtatcacagccatcacg
caccagaataagattttgagcagtgtccaggcaatgcgaacccaaatgcagcagatgcac
ggcagaatggttcccgtctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (10)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (42)   
   RefSeq(nuc) (4)   
   GenBank (19)   
   EMBL (19)   
3D Structure (17)   
   PDB (17)   
Protein domain (16)   
   Pfam (16)   
All databases (92)   

Download RDF
KEGG   Homo sapiens (human): 2044
Entry
2044              CDS       T01001                                 
Symbol
EPHA5, CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4
Name
(RefSeq) EPH receptor A5
  KO
K05106  Eph receptor A5 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2044 (EPHA5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2044 (EPHA5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2044 (EPHA5)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2044 (EPHA5)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_1 SAM_2 Pur_ac_phosph_N Ig_DSCAM-DSCAML_C Ephrin_rec_like CRLF2-like_D2 ABC1 HNH_5 DUF4998 Haspin_kinase Kdo
Other DBs
NCBI-GeneID: 2044
NCBI-ProteinID: NP_004430
OMIM: 600004
HGNC: 3389
Ensembl: ENSG00000145242
UniProt: P54756 A0A384MU00 B7ZKJ3 Q59FT4
Structure
Position
4:complement(65319567..65670489)
AA seq 1037 aa
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE
CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
NSLQEMKVQLVNGMVPL
NT seq 3114 nt   +upstreamnt  +downstreamnt
atgcggggctcggggccccggggtgcgggacgccggcggcccccaagcggcggcggcgac
acccccatcaccccagcgtccctggccggctgctactctgcacctcgacgggctcccctc
tggacgtgccttctcctgtgcgccgcactccggaccctcctggccagccccagcaacgaa
gtgaatttattggattcacgcactgtcatgggggacctgggatggattgcttttccaaaa
aatgggtgggaagagattggtgaagtggatgaaaattatgcccctatccacacataccaa
gtatgcaaagtgatggaacagaatcagaataactggcttttgaccagttggatctccaat
gaaggtgcttccagaatcttcatagaactcaaatttaccctgcgggactgcaacagcctt
cctggaggactggggacctgtaaggaaacctttaatatgtattactttgagtcagatgat
cagaatgggagaaacatcaaggaaaaccaatacatcaaaattgataccattgctgccgat
gaaagctttacagaacttgatcttggtgaccgtgttatgaaactgaatacagaggtcaga
gatgtaggacctctaagcaaaaagggattttatcttgcttttcaagatgttggtgcttgc
attgctctggtttctgtgcgtgtatactataaaaaatgcccttctgtggtacgacacttg
gctgtcttccctgacaccatcactggagctgattcttcccaattgctcgaagtgtcaggc
tcctgtgtcaaccattctgtgaccgatgaacctcccaaaatgcactgcagcgccgaaggg
gagtggctggtgcccatcgggaaatgcatgtgcaaggcaggatatgaagagaaaaatggc
acctgtcaagtgtgcagacctgggttcttcaaagcctcacctcacatccagagctgcggc
aaatgtccacctcacagttatacccatgaggaagcttcaacctcttgtgtctgtgaaaag
gattatttcaggagagagtctgatccacccacaatggcatgcacaagacccccctctgct
cctcggaatgccatctcaaatgttaatgaaactagtgtctttctggaatggattccgcct
gctgacactggtggaaggaaagacgtgtcatattatattgcatgcaagaagtgcaactcc
catgcaggtgtgtgtgaggagtgtggcggtcatgtcaggtaccttccccggcaaagcggc
ctgaaaaacacctctgtcatgatggtggatctactcgctcacacaaactatacctttgag
attgaggcagtgaatggagtgtccgacttgagcccaggagcccggcagtatgtgtctgta
aatgtaaccacaaatcaagcagctccatctccagtcaccaatgtgaaaaaagggaaaatt
gcaaaaaacagcatctctttgtcttggcaagaaccagatcgtcccaatggaatcatccta
gagtatgaaatcaagtattttgaaaaggaccaagagaccagctacacgattatcaaatct
aaagagacaactattactgcagagggcttgaaaccagcttcagtttatgtcttccaaatt
cgagcacgtacagcagcaggctatggtgtcttcagtcgaagatttgagtttgaaaccacc
ccagtgtttgcagcatccagcgatcaaagccagattcctgtaattgctgtgtctgtgaca
gtgggagtcattttgttggcagtggttatcggcgtcctcctcagtggaagttgctgcgaa
tgtggctgtgggagggcttcttccctgtgcgctgttgcccatccaagcctaatatggcgg
tgtggctacagcaaagcaaaacaagatccagaagaggaaaagatgcattttcataatggg
cacattaaactgccaggagtaagaacttacattgatccacatacctatgaggatcccaat
caagctgtccacgaatttgctaaggagatagaagcatcatgtatcaccattgagagagtt
attggagcaggtgaatttggtgaagtttgtagtggacgtttgaaactaccaggaaaaaga
gaattacctgtggctatcaaaacccttaaagtaggctatactgaaaagcaacgcagagat
ttcctaggtgaagcaagtatcatgggacagtttgatcatcctaacatcatccatttagaa
ggtgtggtgaccaaaagtaaaccagtgatgatcgtgacagagtatatggagaatggctct
ttagatacatttttgaagaaaaacgatgggcagttcactgtgattcagcttgttggcatg
ctgagaggtatctctgcaggaatgaagtacctttctgacatgggctatgtgcatagagat
cttgctgccagaaacatcttaatcaacagtaaccttgtgtgcaaagtgtctgactttgga
ctttcccgggtactggaagatgatcccgaggcagcctacaccacaaggggaggaaaaatt
ccaatcagatggactgccccagaagcaatagctttccgaaagtttacttctgccagtgat
gtctggagttatggaatagtaatgtgggaagttgtgtcttatggagagagaccctactgg
gagatgaccaatcaagatgtgattaaagcggtagaggaaggctatcgtctgccaagcccc
atggattgtcctgctgctctctatcagttaatgctggattgctggcagaaagagcgaaat
agcaggcccaagtttgatgaaatagtcaacatgttggacaagctgatacgtaacccaagt
agtctgaagacgctggttaatgcatcctgcagagtatctaatttattggcagaacatagc
ccactaggatctggggcctacagatcagtaggtgaatggctagaggcaatcaagatgggc
cggtatacagagattttcatggaaaatggatacagttcaatggacgctgtggctcaggtg
accttggaggatttgagacggcttggagtgactcttgtcggtcaccagaagaagatcatg
aacagccttcaagaaatgaaggtgcagctggtaaacggaatggtgccattgtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (20)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (29)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (24)   
DNA sequence (44)   
   RefSeq(nuc) (24)   
   GenBank (10)   
   EMBL (10)   
3D Structure (2)   
   PDB (2)   
Protein domain (16)   
   Pfam (16)   
All databases (112)   

Download RDF
KEGG   Homo sapiens (human): 2045
Entry
2045              CDS       T01001                                 
Symbol
EPHA7, EHK-3, EHK3, EK11, HEK11
Name
(RefSeq) EPH receptor A7
  KO
K05108  EphA7 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2045 (EPHA7)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2045 (EPHA7)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2045 (EPHA7)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2045 (EPHA7)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_1 SAM_2 Ig_DSCAM-DSCAML_C Pur_ac_phosph_N Ephrin_rec_like Tissue_fac CRLF2-like_D2 DUF4998 Interfer-bind ABC1 Haspin_kinase FtrD-like Kdo Pkinase_fungal
Other DBs
NCBI-GeneID: 2045
NCBI-ProteinID: NP_004431
OMIM: 602190
HGNC: 3390
Ensembl: ENSG00000135333
UniProt: Q15375
Structure
Position
6:complement(93240020..93419559)
AA seq 998 aa
MVFQTRYPSWIILCYIWLLRFAHTGEAQAAKEVLLLDSKAQQTELEWISSPPNGWEEISG
LDENYTPIRTYQVCQVMEPNQNNWLRTNWISKGNAQRIFVELKFTLRDCNSLPGVLGTCK
ETFNLYYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKK
GFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEE
EAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHS
FSDKEGSSRCECEDGYYRAPSDPPYVACTRPPSAPQNLIFNINQTTVSLEWSPPADNGGR
NDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNG
VSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKY
YEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATG
KMFEATAVSSEQNPVIIIAVVAVAGTIILVFMVFGFIIGRRHCGYSKADQEGDEELYFHF
KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDV
AVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALD
AFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLS
RVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDM
SNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSL
KTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTI
EDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGTGIQV
NT seq 2997 nt   +upstreamnt  +downstreamnt
atggtttttcaaactcggtacccttcatggattattttatgctacatctggctgctccgc
tttgcacacacaggggaggcgcaggctgcgaaggaagtactactgctggattctaaagca
caacaaacagagttggagtggatttcctctccacccaatgggtgggaagaaattagtggt
ttggatgagaactataccccgatacgaacataccaggtgtgccaagtcatggagcccaac
caaaacaactggctgcggactaactggatttccaaaggcaatgcacaaaggatttttgta
gaattgaaattcaccctgagggattgtaacagtcttcctggagtactgggaacttgcaag
gaaacatttaatttgtactattatgaaacagactatgacactggcaggaatataagagaa
aacctctatgtaaaaatagacaccattgctgcagatgaaagttttacccaaggtgacctt
ggtgaaagaaagatgaagcttaacactgaggtgagagagattggacctttgtccaaaaag
ggattctatcttgcctttcaggatgtaggggcttgcatagctttggtttctgtcaaagtg
tactacaagaagtgctggtccattattgagaacttagctatctttccagatacagtgact
ggttcagaattttcctctttagtcgaggttcgagggacatgtgtcagcagtgcagaggaa
gaagcggaaaacgcccccaggatgcactgcagtgcagaaggagaatggttagtgcccatt
ggaaaatgtatctgcaaagcaggctaccagcaaaaaggagacacttgtgaaccctgtggc
cgtgggttctacaagtcttcctctcaagatcttcagtgctctcgttgtccaactcacagt
ttttctgataaagaaggctcctccagatgtgaatgtgaagatgggtattacagggctcca
tctgacccaccatacgttgcgtgcacaaggcctccatctgcaccacagaacctcattttc
aacatcaaccaaaccacagtaagtttggaatggagtcctcctgcagacaatgggggaaga
aacgatgtgacctacagaatattgtgtaagcggtgcagttgggagcagggcgaatgtgtt
ccctgtgggagtaacattggatacatgccccagcagactggattagaggataactatgtc
actgtcatggacctgctagcccacgctaattatacttttgaagttgaagctgtaaatgga
gtttctgacttaagccgatcccagaggctctttgctgctgtcagtatcaccactggtcaa
gcagctccctcgcaagtgagtggagtaatgaaggagagagtactgcagcggagtgtcgag
ctttcctggcaggaaccagagcatcccaatggagtcatcacagaatatgaaatcaagtat
tacgagaaagatcaaagggaacggacctactcaacagtaaaaaccaagtctacttcagcc
tccattaataatctgaaaccaggaacagtgtatgttttccagattcgggcttttactgct
gctggttatggaaattacagtcccagacttgatgttgctacactagaggaagctacaggt
aaaatgtttgaagctacagctgtctccagtgaacagaatcctgttattatcattgctgtg
gttgctgtagctgggaccatcattttggtgttcatggtctttggcttcatcattgggaga
aggcactgtggttatagcaaagctgaccaagaaggcgatgaagagctttactttcatttt
aaatttccaggcaccaaaacctacattgaccctgaaacctatgaggacccaaatagagct
gtccatcaattcgccaaggagctagatgcctcctgtattaaaattgagcgtgtgattggt
gcaggagaattcggtgaagtctgcagtggccgtttgaaacttccagggaaaagagatgtt
gcagtagccataaaaaccctgaaagttggttacacagaaaaacaaaggagagactttttg
tgtgaagcaagcatcatggggcagtttgaccacccgaatgttgtccatttggaaggggtt
gttacaagagggaaaccagtcatgatagtaatagagttcatggaaaatggagccctagat
gcatttctcaggaaacatgatgggcaatttacagtcattcagttagtaggaatgctgaga
ggaattgctgctggaatgagatatttggctgatatgggatatgttcacagggaccttgca
gctcgcaatattcttgtcaacagcaatctcgtttgtaaagtgtcagattttggcctgtcc
cgagttatagaggatgatccagaagctgtctatacaactactggtggaaaaattccagta
aggtggacagcacccgaagccatccagtaccggaaattcacatcagccagtgatgtatgg
agctatggaatagtcatgtgggaagttatgtcttatggagaaagaccttattgggacatg
tcaaatcaagatgttataaaagcaatagaagaaggttatcgtttaccagcacccatggac
tgcccagctggccttcaccagctaatgttggattgttggcaaaaggagcgtgctgaaagg
ccaaaatttgaacagatagttggaattctagacaaaatgattcgaaacccaaatagtctg
aaaactcccctgggaacttgtagtaggccaataagccctcttctggatcaaaacactcct
gatttcactaccttttgttcagttggagaatggctacaagctattaagatggaaagatat
aaagataatttcacggcagctggctacaattcccttgaatcagtagccaggatgactatt
gaggatgtgatgagtttagggatcacactggttggtcatcaaaagaaaatcatgagcagc
attcagactatgagagcacaaatgctacatttacatggaactggcattcaagtgtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (14)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (16)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (14)   
DNA sequence (37)   
   RefSeq(nuc) (15)   
   GenBank (11)   
   EMBL (11)   
3D Structure (7)   
   PDB (7)   
Protein domain (19)   
   Pfam (19)   
All databases (94)   

Download RDF
KEGG   Homo sapiens (human): 2046
Entry
2046              CDS       T01001                                 
Symbol
EPHA8, EEK, EK3, HEK3
Name
(RefSeq) EPH receptor A8
  KO
K05109  Eph receptor A8 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2046 (EPHA8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2046 (EPHA8)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2046 (EPHA8)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2046 (EPHA8)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 SAM_1 EphA2_TM SAM_2 Pur_ac_phosph_N fn3_2 Ig_DSCAM-DSCAML_C Kdo Ephrin_rec_like SusE CRLF2-like_D2 KASH ABC1 Haspin_kinase Interfer-bind
Other DBs
NCBI-GeneID: 2046
NCBI-ProteinID: NP_065387
OMIM: 176945
HGNC: 3391
Ensembl: ENSG00000070886
UniProt: P29322
Structure
Position
1:22563489..22603595
AA seq 1005 aa
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK
DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT
RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP
PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR
DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS
LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG
LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW
NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE
SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG
MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL
NT seq 3018 nt   +upstreamnt  +downstreamnt
atggcccccgcccggggccgcctgccccctgcgctctgggtcgtcacggccgcggcggcg
gcggccacctgcgtgtccgcggcgcgcggcgaagtgaatttgctggacacgtcgaccatc
cacggggactggggctggctcacgtatccggctcatgggtgggactccatcaacgaggtg
gacgagtccttccagcccatccacacgtaccaggtttgcaacgtcatgagccccaaccag
aacaactggctgcgcacgagctgggtcccccgagacggcgcccggcgcgtctatgctgag
atcaagtttaccctgcgcgactgcaacagcatgcctggtgtgctgggcacctgcaaggag
accttcaacctctactacctggagtcggaccgcgacctgggggccagcacacaagaaagc
cagttcctcaaaatcgacaccattgcggccgacgagagcttcacaggtgccgaccttggt
gtgcggcgtctcaagctcaacacggaggtgcgcagtgtgggtcccctcagcaagcgcggc
ttctacctggccttccaggacataggtgcctgcctggccatcctctctctccgcatctac
tataagaagtgccctgccatggtgcgcaatctggctgccttctcggaggcagtgacgggg
gccgactcgtcctcactggtggaggtgaggggccagtgcgtgcggcactcagaggagcgg
gacacacccaagatgtactgcagcgcggagggcgagtggctcgtgcccatcggcaaatgc
gtgtgcagtgccggctacgaggagcggcgggatgcctgtgtggcctgtgagctgggcttc
tacaagtcagcccctggggaccagctgtgtgcccgctgccctccccacagccactccgca
gctccagccgcccaagcctgccactgtgacctcagctactaccgtgcagccctggacccg
ccgtcctcagcctgcacccggccaccctcggcaccagtgaacctgatctccagtgtgaat
gggacatcagtgactctggagtgggcccctcccctggacccaggtggccgcagtgacatc
acctacaatgccgtgtgccgccgctgcccctgggcactgagccgctgcgaggcatgtggg
agcggcacccgctttgtgccccagcagacaagcctggtgcaggccagcctgctggtggcc
aacctgctggcccacatgaactactccttctggatcgaggccgtcaatggcgtgtccgac
ctgagccccgagccccgccgggccgctgtggtcaacatcaccacgaaccaggcagccccg
tcccaggtggtggtgatccgtcaagagcgggcggggcagaccagcgtctcgctgctgtgg
caggagcccgagcagccgaacggcatcatcctggagtatgagatcaagtactacgagaag
gacaaggagatgcagagctactccaccctcaaggccgtcaccaccagagccaccgtctcc
ggcctcaagccgggcacccgctacgtgttccaggtccgagcccgcacctcagcaggctgt
ggccgcttcagccaggccatggaggtggagaccgggaaaccccggccccgctatgacacc
aggaccattgtctggatctgcctgacgctcatcacgggcctggtggtgcttctgctcctg
ctcatctgcaagaagaggcactgtggctacagcaaggccttccaggactcggacgaggag
aagatgcactatcagaatggacaggcacccccacctgtcttcctgcctctgcatcacccc
ccgggaaagctcccagagccccagttctatgcggaaccccacacctacgaggagccaggc
cgggcgggccgcagtttcactcgggagatcgaggcctctaggatccacatcgagaaaatc
atcggctctggagactccggggaagtctgctacgggaggctgcgggtgccagggcagcgg
gatgtgcccgtggccatcaaggccctcaaagccggctacacggagagacagaggcgggac
ttcctgagcgaggcgtccatcatggggcaattcgaccatcccaacatcatccgcctcgag
ggtgtcgtcacccgtggccgcctggcaatgattgtgactgagtacatggagaacggctct
ctggacaccttcctgaggacccacgacgggcagttcaccatcatgcagctggtgggcatg
ctgagaggagtgggtgccggcatgcgctacctctcagacctgggctatgtccaccgagac
ctggccgcccgcaacgtcctggttgacagcaacctggtctgcaaggtgtctgacttcggg
ctctcacgggtgctggaggacgacccggatgctgcctacaccaccacgggcgggaagatc
cccatccgctggacggccccagaggccatcgccttccgcaccttctcctcggccagcgac
gtgtggagcttcggcgtggtcatgtgggaggtgctggcctatggggagcggccctactgg
aacatgaccaaccgggatgtcatcagctctgtggaggaggggtaccgcctgcccgcaccc
atgggctgcccccacgccctgcaccagctcatgctcgactgttggcacaaggaccgggcg
cagcggcctcgcttctcccagattgtcagtgtcctcgatgcgctcatccgcagccctgag
agtctcagggccaccgccacagtcagcaggtgcccaccccctgccttcgtccggagctgc
tttgacctccgagggggcagcggtggcggtgggggcctcaccgtgggggactggctggac
tccatccgcatgggccggtaccgagaccacttcgctgcgggcggatactcctctctgggc
atggtgctacgcatgaacgcccaggacgtgcgcgccctgggcatcaccctcatgggccac
cagaagaagatcctgggcagcattcagaccatgcgggcccagctgaccagcacccagggg
ccccgccggcacctctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (20)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (22)   
   RefSeq(nuc) (14)   
   GenBank (4)   
   EMBL (4)   
3D Structure (3)   
   PDB (3)   
Protein domain (18)   
   Pfam (18)   
All databases (78)   

Download RDF
KEGG   Homo sapiens (human): 285220
Entry
285220            CDS       T01001                                 
Symbol
EPHA6, EHK-2, EHK2, EK12, EPA6, HEK12, PRO57066
Name
(RefSeq) EPH receptor A6
  KO
K05107  Eph receptor A6 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    285220 (EPHA6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    285220 (EPHA6)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     285220 (EPHA6)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   285220 (EPHA6)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase EphA2_TM ABC1 Haspin_kinase Kdo UPF0542 Pkinase_fungal
Other DBs
NCBI-GeneID: 285220
NCBI-ProteinID: NP_001265229
OMIM: 600066
HGNC: 19296
Ensembl: ENSG00000080224
UniProt: Q9UF33
Position
3:96814594..97761532
AA seq 398 aa
MKDSPFQVTKLYWLNEKWDFIASASDMAAEQGQILVIATAAVGGFTLLVILTLFFLITGR
CQWYIKAKMKSEEKRRNHLQNGHLRFPGIKTYIDPDTYEDPSLAVHEFAKEIDPSRIRIE
RVIGAGEFGEVCSGRLKTPGKREIPVAIKTLKGGHMDRQRRDFLREASIMGQFDHPNIIR
LEGVVTKRSFPAIGVEAFCPSFLRAGFLNSIQAPHPVPGGGSLPPRIPAGRPVMIVVEYM
ENGSLDSFLRKHDGHFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILVNSNLVCKV
SDFGLSRVLEDDPEAAYTTTRPTNHNKEQSELVKEDGLESLCEQCESSSGYGTGLVLMWK
RNRRAMGASGQTRKQCDKRDNPPTDLFQTLTLNLCYSA
NT seq 1197 nt   +upstreamnt  +downstreamnt
atgaaagactctccatttcaagtgacaaaactgtactggcttaatgaaaagtgggacttt
attgcctcagcttctgacatggcagcagaacaaggacagattctcgtgatagccaccgcc
gctgttggcggattcactctcctcgtcatcctcactttattcttcttgatcactgggaga
tgtcagtggtacataaaagccaagatgaagtcagaagagaagagaagaaaccacttacag
aatgggcatttgcgcttcccgggaattaaaacttacattgatccagatacatatgaagac
ccatccctagcagtccatgaatttgcaaaggagattgatccctcaagaattcgtattgag
agagtcattggggcaggtgaatttggagaagtctgtagtgggcgtttgaagacaccaggg
aaaagagagatcccagttgccattaaaactttgaaaggtggccacatggatcggcaaaga
agagattttctaagagaagctagtatcatgggccagtttgaccatccaaacatcattcgc
ctagaaggggttgtcaccaaaagatccttcccggccattggggtggaggcgttttgcccc
agcttcctgagggcagggtttttaaatagcatccaggccccgcatccagtgccaggggga
ggatctttgccccccaggattcctgctggcagaccagtaatgattgtggtggaatatatg
gagaatggatccctagactcctttttgcggaagcatgatggccacttcacagtcatccag
ttggtcggaatgctccgaggcattgcatcaggcatgaagtatctttctgatatgggttat
gttcatcgagacctagcggctcggaatatactggtcaatagcaacttagtatgcaaagtt
tctgattttggtctctccagagtgctggaagatgatccagaagctgcttatacaacaact
agacccacaaatcacaacaaagagcaatcagaactggttaaagaagatggtctggaaagc
ttgtgtgagcagtgcgagtccagctctggttatggtactggactggtcctcatgtggaag
agaaacagaagggccatgggagccagtggccagaccagaaagcaatgtgacaagagagat
aaccctccaacagacctcttccaaactctaacacttaacctctgctattctgcataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (6)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (38)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (36)   
DNA sequence (72)   
   RefSeq(nuc) (40)   
   GenBank (16)   
   EMBL (16)   
Protein domain (8)   
   Pfam (8)   
All databases (125)   

Download RDF
DBGET integrated database retrieval system