KEGG   Homo sapiens (human): 2042Help
Entry
2042              CDS       T01001                                 

Gene name
EPHA3, EK4, ETK, ETK1, HEK, HEK4, TYRO4
Definition
(RefSeq) EPH receptor A3
  KO
K05104  Eph receptor A3 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development
   04360 Axon guidance
    2042 (EPHA3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2042 (EPHA3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2042 (EPHA3)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2042 (EPHA3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_2 SAM_1 Pur_ac_phosph_N Ephrin_rec_like fn3_2 TMEM154 Haspin_kinase Kdo SusE Pkinase_fungal
Motif
Other DBs
NCBI-GeneID: 2042
NCBI-ProteinID: NP_005224
OMIM: 179611
HGNC: 3387
Ensembl: ENSG00000044524
Vega: OTTHUMG00000159040
Pharos: P29320(Tchem)
UniProt: P29320 A0A140VJJ0 Q6P4R6
Structure
PDB: 

Position
3p11.1
AA seq 983 aa AA seqDB search
MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE
HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF
NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY
LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP
RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG
SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN
IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS
PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ
ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDSFSISGESS
QVVMIAISAAVAIILLTVVIYVLIGRFCGYKSKHGADEKRLHFGNGHLKLPGLRTYVDPH
TYEDPTQAVHEFAKELDATNISIDKVVGAGEFGEVCSGRLKLPSKKEISVAIKTLKVGYT
EKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGSLDSFLRKHDAQFTV
IQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYT
TRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVIKAVDEG
YRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARPSN
LLLDQSNVDITTFRTTGDWLNGVWTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG
PQKKIISSIKALETQSKNGPVPV
NT seq 2952 nt NT seq  +upstreamnt  +downstreamnt
atggattgtcagctctccatcctcctccttctcagctgctctgttctcgacagcttcggg
gaactgattccgcagccttccaatgaagtcaatctactggattcaaaaacaattcaaggg
gagctgggctggatctcttatccatcacatgggtgggaagagatcagtggtgtggatgaa
cattacacacccatcaggacttaccaggtgtgcaatgtcatggaccacagtcaaaacaat
tggctgagaacaaactgggtccccaggaactcagctcagaagatttatgtggagctcaag
ttcactctacgagactgcaatagcattccattggttttaggaacttgcaaggagacattc
aacctgtactacatggagtctgatgatgatcatggggtgaaatttcgagagcatcagttt
acaaagattgacaccattgcagctgatgaaagtttcactcaaatggatcttggggaccgt
attctgaagctcaacactgagattagagaagtaggtcctgtcaacaagaagggattttat
ttggcatttcaagatgttggtgcttgtgttgccttggtgtctgtgagagtatacttcaaa
aagtgcccatttacagtgaagaatctggctatgtttccagacacggtacccatggactcc
cagtccctggtggaggttagagggtcttgtgtcaacaattctaaggaggaagatcctcca
aggatgtactgcagtacagaaggcgaatggcttgtacccattggcaagtgttcctgcaat
gctggctatgaagaaagaggttttatgtgccaagcttgtcgaccaggtttctacaaggca
ttggatggtaatatgaagtgtgctaagtgcccgcctcacagttctactcaggaagatggt
tcaatgaactgcaggtgtgagaataattacttccgggcagacaaagaccctccatccatg
gcttgtacccgacctccatcttcaccaagaaatgttatctctaatataaacgagacctca
gttatcctggactggagttggcccctggacacaggaggccggaaagatgttaccttcaac
atcatatgtaaaaaatgtgggtggaatataaaacagtgtgagccatgcagcccaaatgtc
cgcttcctccctcgacagtttggactcaccaacaccacggtgacagtgacagaccttctg
gcacatactaactacacctttgagattgatgccgttaatggggtgtcagagctgagctcc
ccaccaagacagtttgctgcggtcagcatcacaactaatcaggctgctccatcacctgtc
ctgacgattaagaaagatcggacctccagaaatagcatctctttgtcctggcaagaacct
gaacatcctaatgggatcatattggactacgaggtcaaatactatgaaaagcaggaacaa
gaaacaagttataccattctgagggcaagaggcacaaatgttaccatcagtagcctcaag
cctgacactatatacgtattccaaatccgagcccgaacagccgctggatatgggacgaac
agccgcaagtttgagtttgaaactagtccagactctttctccatctctggtgaaagtagc
caagtggtcatgatcgccatttcagcggcagtagcaattattctcctcactgttgtcatc
tatgttttgattgggaggttctgtggctataagtcaaaacatggggcagatgaaaaaaga
cttcattttggcaatgggcatttaaaacttccaggtctcaggacttatgttgacccacat
acatatgaagaccctacccaagctgttcatgagtttgccaaggaattggatgccaccaac
atatccattgataaagttgttggagcaggtgaatttggagaggtgtgcagtggtcgctta
aaacttccttcaaaaaaagagatttcagtggccattaagaccctgaaagttggctacaca
gaaaagcagaggagagacttcctgggagaagcaagcattatgggacagtttgaccacccc
aatatcattcgactggaaggagttgttaccaaaagtaagccagttatgattgtcacagaa
tacatggagaatggttccttggatagtttcctacgtaaacacgatgcccagtttactgtc
attcagctagtggggatgcttcgagggatagcatctggcatgaagtacctgtcagacatg
ggctatgttcaccgagacctcgctgctcggaacatcttgatcaacagtaacttggtgtgt
aaggtttctgatttcggactttcgcgtgtcctggaggatgacccagaagctgcttataca
acaagaggagggaagatcccaatcaggtggacatcaccagaagctatagcctaccgcaag
ttcacgtcagccagcgatgtatggagttatgggattgttctctgggaggtgatgtcttat
ggagagagaccatactgggagatgtccaatcaggatgtaattaaagctgtagatgagggc
tatcgactgccaccccccatggactgcccagctgccttgtatcagctgatgctggactgc
tggcagaaagacaggaacaacagacccaagtttgagcagattgttagtattctggacaag
cttatccggaatcccggcagcctgaagatcatcaccagtgcagccgcaaggccatcaaac
cttcttctggaccaaagcaatgtggatatcactaccttccgcacaacaggtgactggctt
aatggtgtctggacagcacactgcaaggaaatcttcacgggtgtggagtacagttcttgt
gacacaatagccaagatttccacagatgacatgaaaaaggttggtgtcaccgtggttggg
ccacagaagaagatcatcagtagcattaaagctctagaaacgcaatcaaagaatggccca
gttcccgtgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (22)   
   RefSeq(nuc) (4)   
   GenBank (9)   
   EMBL (9)   
Protein domain (15)   
   Pfam (15)   
All databases (68)   

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