KEGG   Homo sapiens (human): 2044Help
Entry
2044              CDS       T01001                                 

Gene name
EPHA5, CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4
Definition
(RefSeq) EPH receptor A5
  KO
K05106  Eph receptor A5 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2044 (EPHA5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2044 (EPHA5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2044 (EPHA5)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2044 (EPHA5)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Ephrin_lbd Pkinase fn3 EphA2_TM SAM_1 SAM_2 Ephrin_rec_like Pur_ac_phosph_N HNH_5 Haspin_kinase DUF4998 Kdo
Motif
Other DBs
NCBI-GeneID: 2044
NCBI-ProteinID: NP_004430
OMIM: 600004
HGNC: 3389
Ensembl: ENSG00000145242
Vega: OTTHUMG00000129273
Pharos: P54756(Tchem)
UniProt: P54756 B7ZKJ3 A0A384MU00 Q59FT4
Structure
PDB: 

Position
4q13.1-q13.2
AA seq 1037 aa AA seqDB search
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE
CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
NSLQEMKVQLVNGMVPL
NT seq 3114 nt NT seq  +upstreamnt  +downstreamnt
atgcggggctcggggccccggggtgcgggacgccggcggcccccaagcggcggcggcgac
acccccatcaccccagcgtccctggccggctgctactctgcacctcgacgggctcccctc
tggacgtgccttctcctgtgcgccgcactccggaccctcctggccagccccagcaacgaa
gtgaatttattggattcacgcactgtcatgggggacctgggatggattgcttttccaaaa
aatgggtgggaagagattggtgaagtggatgaaaattatgcccctatccacacataccaa
gtatgcaaagtgatggaacagaatcagaataactggcttttgaccagttggatctccaat
gaaggtgcttccagaatcttcatagaactcaaatttaccctgcgggactgcaacagcctt
cctggaggactggggacctgtaaggaaacctttaatatgtattactttgagtcagatgat
cagaatgggagaaacatcaaggaaaaccaatacatcaaaattgataccattgctgccgat
gaaagctttacagaacttgatcttggtgaccgtgttatgaaactgaatacagaggtcaga
gatgtaggacctctaagcaaaaagggattttatcttgcttttcaagatgttggtgcttgc
attgctctggtttctgtgcgtgtatactataaaaaatgcccttctgtggtacgacacttg
gctgtcttccctgacaccatcactggagctgattcttcccaattgctcgaagtgtcaggc
tcctgtgtcaaccattctgtgaccgatgaacctcccaaaatgcactgcagcgccgaaggg
gagtggctggtgcccatcgggaaatgcatgtgcaaggcaggatatgaagagaaaaatggc
acctgtcaagtgtgcagacctgggttcttcaaagcctcacctcacatccagagctgcggc
aaatgtccacctcacagttatacccatgaggaagcttcaacctcttgtgtctgtgaaaag
gattatttcaggagagagtctgatccacccacaatggcatgcacaagacccccctctgct
cctcggaatgccatctcaaatgttaatgaaactagtgtctttctggaatggattccgcct
gctgacactggtggaaggaaagacgtgtcatattatattgcatgcaagaagtgcaactcc
catgcaggtgtgtgtgaggagtgtggcggtcatgtcaggtaccttccccggcaaagcggc
ctgaaaaacacctctgtcatgatggtggatctactcgctcacacaaactatacctttgag
attgaggcagtgaatggagtgtccgacttgagcccaggagcccggcagtatgtgtctgta
aatgtaaccacaaatcaagcagctccatctccagtcaccaatgtgaaaaaagggaaaatt
gcaaaaaacagcatctctttgtcttggcaagaaccagatcgtcccaatggaatcatccta
gagtatgaaatcaagtattttgaaaaggaccaagagaccagctacacgattatcaaatct
aaagagacaactattactgcagagggcttgaaaccagcttcagtttatgtcttccaaatt
cgagcacgtacagcagcaggctatggtgtcttcagtcgaagatttgagtttgaaaccacc
ccagtgtttgcagcatccagcgatcaaagccagattcctgtaattgctgtgtctgtgaca
gtgggagtcattttgttggcagtggttatcggcgtcctcctcagtggaagttgctgcgaa
tgtggctgtgggagggcttcttccctgtgcgctgttgcccatccaagcctaatatggcgg
tgtggctacagcaaagcaaaacaagatccagaagaggaaaagatgcattttcataatggg
cacattaaactgccaggagtaagaacttacattgatccacatacctatgaggatcccaat
caagctgtccacgaatttgctaaggagatagaagcatcatgtatcaccattgagagagtt
attggagcaggtgaatttggtgaagtttgtagtggacgtttgaaactaccaggaaaaaga
gaattacctgtggctatcaaaacccttaaagtaggctatactgaaaagcaacgcagagat
ttcctaggtgaagcaagtatcatgggacagtttgatcatcctaacatcatccatttagaa
ggtgtggtgaccaaaagtaaaccagtgatgatcgtgacagagtatatggagaatggctct
ttagatacatttttgaagaaaaacgatgggcagttcactgtgattcagcttgttggcatg
ctgagaggtatctctgcaggaatgaagtacctttctgacatgggctatgtgcatagagat
cttgctgccagaaacatcttaatcaacagtaaccttgtgtgcaaagtgtctgactttgga
ctttcccgggtactggaagatgatcccgaggcagcctacaccacaaggggaggaaaaatt
ccaatcagatggactgccccagaagcaatagctttccgaaagtttacttctgccagtgat
gtctggagttatggaatagtaatgtgggaagttgtgtcttatggagagagaccctactgg
gagatgaccaatcaagatgtgattaaagcggtagaggaaggctatcgtctgccaagcccc
atggattgtcctgctgctctctatcagttaatgctggattgctggcagaaagagcgaaat
agcaggcccaagtttgatgaaatagtcaacatgttggacaagctgatacgtaacccaagt
agtctgaagacgctggttaatgcatcctgcagagtatctaatttattggcagaacatagc
ccactaggatctggggcctacagatcagtaggtgaatggctagaggcaatcaagatgggc
cggtatacagagattttcatggaaaatggatacagttcaatggacgctgtggctcaggtg
accttggaggatttgagacggcttggagtgactcttgtcggtcaccagaagaagatcatg
aacagccttcaagaaatgaaggtgcagctggtaaacggaatggtgccattgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (17)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (32)   
   RefSeq(nuc) (12)   
   GenBank (10)   
   EMBL (10)   
Protein domain (13)   
   Pfam (13)   
All databases (92)   

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