KEGG   Homo sapiens (human): 2044
Entry
2044              CDS       T01001                                 
Symbol
EPHA5, CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4
Name
(RefSeq) EPH receptor A5
  KO
K05106  Eph receptor A5 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2044 (EPHA5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2044 (EPHA5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2044 (EPHA5)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2044 (EPHA5)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 Ephrin_CRD EphA2_TM SAM_1 SAM_2 Pur_ac_phosph_N FN3_DSCAM-DSCAML_C Ephrin_rec_like ABC1 CRLF2-like_D2 DUF4998 HNH_5 Haspin_kinase Kdo
Other DBs
NCBI-GeneID: 2044
NCBI-ProteinID: NP_004430
OMIM: 600004
HGNC: 3389
Ensembl: ENSG00000145242
UniProt: P54756 A0A384MU00 B7ZKJ3 Q59FT4
Structure
Position
4:complement(65319567..65670489)
AA seq 1037 aa
MRGSGPRGAGRRRPPSGGGDTPITPASLAGCYSAPRRAPLWTCLLLCAALRTLLASPSNE
VNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQVCKVMEQNQNNWLLTSWISN
EGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDDQNGRNIKENQYIKIDTIAAD
ESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGACIALVSVRVYYKKCPSVVRHL
AVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEGEWLVPIGKCMCKAGYEEKNG
TCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEKDYFRRESDPPTMACTRPPSA
PRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNSHAGVCEECGGHVRYLPRQSG
LKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSVNVTTNQAAPSPVTNVKKGKI
AKNSISLSWQEPDRPNGIILEYEIKYFEKDQETSYTIIKSKETTITAEGLKPASVYVFQI
RARTAAGYGVFSRRFEFETTPVFAASSDQSQIPVIAVSVTVGVILLAVVIGVLLSGSCCE
CGCGRASSLCAVAHPSLIWRCGYSKAKQDPEEEKMHFHNGHIKLPGVRTYIDPHTYEDPN
QAVHEFAKEIEASCITIERVIGAGEFGEVCSGRLKLPGKRELPVAIKTLKVGYTEKQRRD
FLGEASIMGQFDHPNIIHLEGVVTKSKPVMIVTEYMENGSLDTFLKKNDGQFTVIQLVGM
LRGISAGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRVLEDDPEAAYTTRGGKI
PIRWTAPEAIAFRKFTSASDVWSYGIVMWEVVSYGERPYWEMTNQDVIKAVEEGYRLPSP
MDCPAALYQLMLDCWQKERNSRPKFDEIVNMLDKLIRNPSSLKTLVNASCRVSNLLAEHS
PLGSGAYRSVGEWLEAIKMGRYTEIFMENGYSSMDAVAQVTLEDLRRLGVTLVGHQKKIM
NSLQEMKVQLVNGMVPL
NT seq 3114 nt   +upstreamnt  +downstreamnt
atgcggggctcggggccccggggtgcgggacgccggcggcccccaagcggcggcggcgac
acccccatcaccccagcgtccctggccggctgctactctgcacctcgacgggctcccctc
tggacgtgccttctcctgtgcgccgcactccggaccctcctggccagccccagcaacgaa
gtgaatttattggattcacgcactgtcatgggggacctgggatggattgcttttccaaaa
aatgggtgggaagagattggtgaagtggatgaaaattatgcccctatccacacataccaa
gtatgcaaagtgatggaacagaatcagaataactggcttttgaccagttggatctccaat
gaaggtgcttccagaatcttcatagaactcaaatttaccctgcgggactgcaacagcctt
cctggaggactggggacctgtaaggaaacctttaatatgtattactttgagtcagatgat
cagaatgggagaaacatcaaggaaaaccaatacatcaaaattgataccattgctgccgat
gaaagctttacagaacttgatcttggtgaccgtgttatgaaactgaatacagaggtcaga
gatgtaggacctctaagcaaaaagggattttatcttgcttttcaagatgttggtgcttgc
attgctctggtttctgtgcgtgtatactataaaaaatgcccttctgtggtacgacacttg
gctgtcttccctgacaccatcactggagctgattcttcccaattgctcgaagtgtcaggc
tcctgtgtcaaccattctgtgaccgatgaacctcccaaaatgcactgcagcgccgaaggg
gagtggctggtgcccatcgggaaatgcatgtgcaaggcaggatatgaagagaaaaatggc
acctgtcaagtgtgcagacctgggttcttcaaagcctcacctcacatccagagctgcggc
aaatgtccacctcacagttatacccatgaggaagcttcaacctcttgtgtctgtgaaaag
gattatttcaggagagagtctgatccacccacaatggcatgcacaagacccccctctgct
cctcggaatgccatctcaaatgttaatgaaactagtgtctttctggaatggattccgcct
gctgacactggtggaaggaaagacgtgtcatattatattgcatgcaagaagtgcaactcc
catgcaggtgtgtgtgaggagtgtggcggtcatgtcaggtaccttccccggcaaagcggc
ctgaaaaacacctctgtcatgatggtggatctactcgctcacacaaactatacctttgag
attgaggcagtgaatggagtgtccgacttgagcccaggagcccggcagtatgtgtctgta
aatgtaaccacaaatcaagcagctccatctccagtcaccaatgtgaaaaaagggaaaatt
gcaaaaaacagcatctctttgtcttggcaagaaccagatcgtcccaatggaatcatccta
gagtatgaaatcaagtattttgaaaaggaccaagagaccagctacacgattatcaaatct
aaagagacaactattactgcagagggcttgaaaccagcttcagtttatgtcttccaaatt
cgagcacgtacagcagcaggctatggtgtcttcagtcgaagatttgagtttgaaaccacc
ccagtgtttgcagcatccagcgatcaaagccagattcctgtaattgctgtgtctgtgaca
gtgggagtcattttgttggcagtggttatcggcgtcctcctcagtggaagttgctgcgaa
tgtggctgtgggagggcttcttccctgtgcgctgttgcccatccaagcctaatatggcgg
tgtggctacagcaaagcaaaacaagatccagaagaggaaaagatgcattttcataatggg
cacattaaactgccaggagtaagaacttacattgatccacatacctatgaggatcccaat
caagctgtccacgaatttgctaaggagatagaagcatcatgtatcaccattgagagagtt
attggagcaggtgaatttggtgaagtttgtagtggacgtttgaaactaccaggaaaaaga
gaattacctgtggctatcaaaacccttaaagtaggctatactgaaaagcaacgcagagat
ttcctaggtgaagcaagtatcatgggacagtttgatcatcctaacatcatccatttagaa
ggtgtggtgaccaaaagtaaaccagtgatgatcgtgacagagtatatggagaatggctct
ttagatacatttttgaagaaaaacgatgggcagttcactgtgattcagcttgttggcatg
ctgagaggtatctctgcaggaatgaagtacctttctgacatgggctatgtgcatagagat
cttgctgccagaaacatcttaatcaacagtaaccttgtgtgcaaagtgtctgactttgga
ctttcccgggtactggaagatgatcccgaggcagcctacaccacaaggggaggaaaaatt
ccaatcagatggactgccccagaagcaatagctttccgaaagtttacttctgccagtgat
gtctggagttatggaatagtaatgtgggaagttgtgtcttatggagagagaccctactgg
gagatgaccaatcaagatgtgattaaagcggtagaggaaggctatcgtctgccaagcccc
atggattgtcctgctgctctctatcagttaatgctggattgctggcagaaagagcgaaat
agcaggcccaagtttgatgaaatagtcaacatgttggacaagctgatacgtaacccaagt
agtctgaagacgctggttaatgcatcctgcagagtatctaatttattggcagaacatagc
ccactaggatctggggcctacagatcagtaggtgaatggctagaggcaatcaagatgggc
cggtatacagagattttcatggaaaatggatacagttcaatggacgctgtggctcaggtg
accttggaggatttgagacggcttggagtgactcttgtcggtcaccagaagaagatcatg
aacagccttcaagaaatgaaggtgcagctggtaaacggaatggtgccattgtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (20)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (4)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (36)   
   RefSeq(nuc) (16)   
   GenBank (10)   
   EMBL (10)   
3D Structure (2)   
   PDB (2)   
Protein domain (17)   
   Pfam (17)   
All databases (97)   

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