KEGG   Homo sapiens (human): 2046
Entry
2046              CDS       T01001                                 
Symbol
EPHA8, EEK, EK3, HEK3
Name
(RefSeq) EPH receptor A8
  KO
K05109  Eph receptor A8 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    2046 (EPHA8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    2046 (EPHA8)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     2046 (EPHA8)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  EPH family [OT]
   2046 (EPHA8)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Ephrin_lbd Pkinase fn3 SAM_1 EphA2_TM SAM_2 Pur_ac_phosph_N fn3_2 Ig_DSCAM-DSCAML_C Kdo Ephrin_rec_like SusE CRLF2-like_D2 KASH ABC1 Haspin_kinase Interfer-bind
Other DBs
NCBI-GeneID: 2046
NCBI-ProteinID: NP_065387
OMIM: 176945
HGNC: 3391
Ensembl: ENSG00000070886
UniProt: P29322
Structure
Position
1:22563489..22603595
AA seq 1005 aa
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
LSPEPRRAAVVNITTNQAAPSQVVVIRQERAGQTSVSLLWQEPEQPNGIILEYEIKYYEK
DKEMQSYSTLKAVTTRATVSGLKPGTRYVFQVRARTSAGCGRFSQAMEVETGKPRPRYDT
RTIVWICLTLITGLVVLLLLLICKKRHCGYSKAFQDSDEEKMHYQNGQAPPPVFLPLHHP
PGKLPEPQFYAEPHTYEEPGRAGRSFTREIEASRIHIEKIIGSGDSGEVCYGRLRVPGQR
DVPVAIKALKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTRGRLAMIVTEYMENGS
LDTFLRTHDGQFTIMQLVGMLRGVGAGMRYLSDLGYVHRDLAARNVLVDSNLVCKVSDFG
LSRVLEDDPDAAYTTTGGKIPIRWTAPEAIAFRTFSSASDVWSFGVVMWEVLAYGERPYW
NMTNRDVISSVEEGYRLPAPMGCPHALHQLMLDCWHKDRAQRPRFSQIVSVLDALIRSPE
SLRATATVSRCPPPAFVRSCFDLRGGSGGGGGLTVGDWLDSIRMGRYRDHFAAGGYSSLG
MVLRMNAQDVRALGITLMGHQKKILGSIQTMRAQLTSTQGPRRHL
NT seq 3018 nt   +upstreamnt  +downstreamnt
atggcccccgcccggggccgcctgccccctgcgctctgggtcgtcacggccgcggcggcg
gcggccacctgcgtgtccgcggcgcgcggcgaagtgaatttgctggacacgtcgaccatc
cacggggactggggctggctcacgtatccggctcatgggtgggactccatcaacgaggtg
gacgagtccttccagcccatccacacgtaccaggtttgcaacgtcatgagccccaaccag
aacaactggctgcgcacgagctgggtcccccgagacggcgcccggcgcgtctatgctgag
atcaagtttaccctgcgcgactgcaacagcatgcctggtgtgctgggcacctgcaaggag
accttcaacctctactacctggagtcggaccgcgacctgggggccagcacacaagaaagc
cagttcctcaaaatcgacaccattgcggccgacgagagcttcacaggtgccgaccttggt
gtgcggcgtctcaagctcaacacggaggtgcgcagtgtgggtcccctcagcaagcgcggc
ttctacctggccttccaggacataggtgcctgcctggccatcctctctctccgcatctac
tataagaagtgccctgccatggtgcgcaatctggctgccttctcggaggcagtgacgggg
gccgactcgtcctcactggtggaggtgaggggccagtgcgtgcggcactcagaggagcgg
gacacacccaagatgtactgcagcgcggagggcgagtggctcgtgcccatcggcaaatgc
gtgtgcagtgccggctacgaggagcggcgggatgcctgtgtggcctgtgagctgggcttc
tacaagtcagcccctggggaccagctgtgtgcccgctgccctccccacagccactccgca
gctccagccgcccaagcctgccactgtgacctcagctactaccgtgcagccctggacccg
ccgtcctcagcctgcacccggccaccctcggcaccagtgaacctgatctccagtgtgaat
gggacatcagtgactctggagtgggcccctcccctggacccaggtggccgcagtgacatc
acctacaatgccgtgtgccgccgctgcccctgggcactgagccgctgcgaggcatgtggg
agcggcacccgctttgtgccccagcagacaagcctggtgcaggccagcctgctggtggcc
aacctgctggcccacatgaactactccttctggatcgaggccgtcaatggcgtgtccgac
ctgagccccgagccccgccgggccgctgtggtcaacatcaccacgaaccaggcagccccg
tcccaggtggtggtgatccgtcaagagcgggcggggcagaccagcgtctcgctgctgtgg
caggagcccgagcagccgaacggcatcatcctggagtatgagatcaagtactacgagaag
gacaaggagatgcagagctactccaccctcaaggccgtcaccaccagagccaccgtctcc
ggcctcaagccgggcacccgctacgtgttccaggtccgagcccgcacctcagcaggctgt
ggccgcttcagccaggccatggaggtggagaccgggaaaccccggccccgctatgacacc
aggaccattgtctggatctgcctgacgctcatcacgggcctggtggtgcttctgctcctg
ctcatctgcaagaagaggcactgtggctacagcaaggccttccaggactcggacgaggag
aagatgcactatcagaatggacaggcacccccacctgtcttcctgcctctgcatcacccc
ccgggaaagctcccagagccccagttctatgcggaaccccacacctacgaggagccaggc
cgggcgggccgcagtttcactcgggagatcgaggcctctaggatccacatcgagaaaatc
atcggctctggagactccggggaagtctgctacgggaggctgcgggtgccagggcagcgg
gatgtgcccgtggccatcaaggccctcaaagccggctacacggagagacagaggcgggac
ttcctgagcgaggcgtccatcatggggcaattcgaccatcccaacatcatccgcctcgag
ggtgtcgtcacccgtggccgcctggcaatgattgtgactgagtacatggagaacggctct
ctggacaccttcctgaggacccacgacgggcagttcaccatcatgcagctggtgggcatg
ctgagaggagtgggtgccggcatgcgctacctctcagacctgggctatgtccaccgagac
ctggccgcccgcaacgtcctggttgacagcaacctggtctgcaaggtgtctgacttcggg
ctctcacgggtgctggaggacgacccggatgctgcctacaccaccacgggcgggaagatc
cccatccgctggacggccccagaggccatcgccttccgcaccttctcctcggccagcgac
gtgtggagcttcggcgtggtcatgtgggaggtgctggcctatggggagcggccctactgg
aacatgaccaaccgggatgtcatcagctctgtggaggaggggtaccgcctgcccgcaccc
atgggctgcccccacgccctgcaccagctcatgctcgactgttggcacaaggaccgggcg
cagcggcctcgcttctcccagattgtcagtgtcctcgatgcgctcatccgcagccctgag
agtctcagggccaccgccacagtcagcaggtgcccaccccctgccttcgtccggagctgc
tttgacctccgagggggcagcggtggcggtgggggcctcaccgtgggggactggctggac
tccatccgcatgggccggtaccgagaccacttcgctgcgggcggatactcctctctgggc
atggtgctacgcatgaacgcccaggacgtgcgcgccctgggcatcaccctcatgggccac
cagaagaagatcctgggcagcattcagaccatgcgggcccagctgaccagcacccagggg
ccccgccggcacctctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (20)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (22)   
   RefSeq(nuc) (14)   
   GenBank (4)   
   EMBL (4)   
3D Structure (3)   
   PDB (3)   
Protein domain (18)   
   Pfam (18)   
All databases (78)   

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