KEGG   Homo sapiens (human): 2053
Entry
2053              CDS       T01001                                 

Gene name
EPHX2, ABHD20, CEH, SEH
Definition
(RefSeq) epoxide hydrolase 2
  KO
K08726  soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00590  Arachidonic acid metabolism
hsa01100  Metabolic pathways
hsa04146  Peroxisome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    2053 (EPHX2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    2053 (EPHX2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    2053 (EPHX2)
   01002 Peptidases and inhibitors [BR:hsa01002]
    2053 (EPHX2)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.76  lipid-phosphate phosphatase
     2053 (EPHX2)
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.10  soluble epoxide hydrolase
     2053 (EPHX2)
Protein phosphatases and associated proteins [BR:hsa01009]
 HAD phosphatases
  Other HAD phosphatases
   2053 (EPHX2)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S33
   2053 (EPHX2)
SSDB
Motif
Pfam: Abhydrolase_1 Abhydrolase_6 Hydrolase_4 HAD_2 Hydrolase Hydrolase_like Resolvase E2_bind Ndr Abhydrolase_2
Other DBs
NCBI-GeneID: 2053
NCBI-ProteinID: NP_001970
OMIM: 132811
HGNC: 3402
Ensembl: ENSG00000120915
Vega: OTTHUMG00000102115
Pharos: P34913(Tchem)
UniProt: P34913
Structure
PDB: 

Position
8p21.2-p21.1
AA seq 555 aa
MTLRAAVFDLDGVLALPAVFGVLGRTEEALALPRGLLNDAFQKGGPEGATTRLMKGEITL
SQWIPLMEENCRKCSETAKVCLPKNFSIKEIFDKAISARKINRPMLQAALMLRKKGFTTA
ILTNTWLDDRAERDGLAQLMCELKMHFDFLIESCQVGMVKPEPQIYKFLLDTLKASPSEV
VFLDDIGANLKPARDLGMVTILVQDTDTALKELEKVTGIQLLNTPAPLPTSCNPSDMSHG
YVTVKPRVRLHFVELGSGPAVCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS
APPEIEEYCMEVLCKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVRAVASLNT
PFIPANPNMSPLESIKANPVFDYQLYFQEPGVAEAELEQNLSRTFKSLFRASDESVLSMH
KVCEAGGLFVNSPEEPSLSRMVTEEEIQFYVQQFKKSGFRGPLNWYRNMERNWKWACKSL
GRKILIPALMVTAEKDFVLVPQMSQHMEDWIPHLKRGHIEDCGHWTQMDKPTEVNQILIK
WLDSDARNPPVVSKM
NT seq 1668 nt   +upstreamnt  +downstreamnt
atgacgctgcgcgcggccgtcttcgaccttgacggggtgctggcgctgccagcggtgttc
ggcgtcctcggccgcacggaggaggccctggcgctgcccagaggacttctgaatgatgct
ttccagaaagggggaccagagggtgccactacccggcttatgaaaggagagatcacactt
tcccagtggataccactcatggaagaaaactgcaggaagtgctccgagaccgctaaagtc
tgcctccccaagaatttctccataaaagaaatctttgacaaggcgatttcagccagaaag
atcaaccgccccatgctccaggcagctctcatgctcaggaagaaaggattcactactgcc
atcctcaccaacacctggctggacgaccgtgctgagagagatggcctggcccagctgatg
tgtgagctgaagatgcactttgacttcctgatagagtcgtgtcaggtgggaatggtcaaa
cctgaacctcagatctacaagtttctgctggacaccctgaaggccagccccagtgaggtc
gtttttttggatgacatcggggctaatctgaagccagcccgtgacttgggaatggtcacc
atcctggtccaggacactgacacggccctgaaagaactggagaaagtgaccggaatccag
cttctcaataccccggcccctctgccgacctcttgcaatccaagtgacatgagccatggg
tacgtgacagtaaagcccagggtccgtctgcattttgtggagctgggctccggccctgct
gtgtgcctctgccatggatttcccgagagttggtattcttggaggtaccagatccctgct
ctggcccaggcaggttaccgggtcctagctatggacatgaaaggctatggagagtcatct
gctcctcccgaaatagaagaatattgcatggaagtgttatgtaaggagatggtaaccttc
ctggataaactgggcctctctcaagcagtgttcattggccatgactggggtggcatgctg
gtgtggtacatggctctcttctaccccgagagagtgagggcggtggccagtttgaatact
cccttcataccagcaaatcccaacatgtcccctttggagagtatcaaagccaacccagta
tttgattaccagctctacttccaagaaccaggagtggctgaggctgaactggaacagaac
ctgagtcggactttcaaaagcctcttcagagcaagcgatgagagtgttttatccatgcat
aaagtctgtgaagcgggaggactttttgtaaatagcccagaagagcccagcctcagcagg
atggtcactgaggaggaaatccagttctatgtgcagcagttcaagaagtctggtttcaga
ggtcctctaaactggtaccgaaacatggaaaggaactggaagtgggcttgcaaaagcttg
ggacggaagatcctgattccggccctgatggtcacggcggagaaggacttcgtgctcgtt
cctcagatgtcccagcacatggaggactggattccccacctgaaaaggggacacattgag
gactgtgggcactggacacagatggacaagccaaccgaggtgaatcagatcctcattaag
tggctggattctgatgcccggaacccaccggtggtctcaaagatgtag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (2)   
   OMIM (2)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (7)   
   KEGG ENZYME (2)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (45)   
   RefSeq(nuc) (7)   
   GenBank (19)   
   EMBL (19)   
Protein domain (10)   
   Pfam (10)   
All databases (116)   

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