| Entry |
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| Symbol |
FCGR1A, CD64, CD64A, FCRI, FcgammaRI, IGFR1
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| Name |
(RefSeq) Fc fragment of IgG receptor Ia
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| KO |
| K06498 | high affinity immunoglobulin gamma Fc receptor I |
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| Organism |
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| Pathway |
| hsa04613 | Neutrophil extracellular trap formation |
| hsa04666 | Fc gamma R-mediated phagocytosis |
| hsa05150 | Staphylococcus aureus infection |
| hsa05202 | Transcriptional misregulation in cancer |
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| Network |
nt06135 Cytoskeletal regulation (viruses and bacteria) nt06240 Transcription nt06275 Acute myeloid leukemia |
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| Element |
| N00112 | AML1-ETO fusion to PU.1-mediated transcription |
| N01090 | IGG-FCGR-RAC signaling pathway |
| N01091 | Escherichia EspJ to IGG-FCGR-RAC signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
2209 (FCGR1A)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
2209 (FCGR1A)
04613 Neutrophil extracellular trap formation
2209 (FCGR1A)
04666 Fc gamma R-mediated phagocytosis
2209 (FCGR1A)
09158 Development and regeneration
04380 Osteoclast differentiation
2209 (FCGR1A)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
2209 (FCGR1A)
09162 Cancer: specific types
05221 Acute myeloid leukemia
2209 (FCGR1A)
09171 Infectious disease: bacterial
05150 Staphylococcus aureus infection
2209 (FCGR1A)
05152 Tuberculosis
2209 (FCGR1A)
09174 Infectious disease: parasitic
05140 Leishmaniasis
2209 (FCGR1A)
09163 Immune disease
05322 Systemic lupus erythematosus
2209 (FCGR1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
2209 (FCGR1A)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:hsa04090]
2209 (FCGR1A)
Membrane trafficking [BR:hsa04131]
Endocytosis
Phagocytosis
Fc receptors
2209 (FCGR1A)
CD molecules [BR:hsa04090]
Proteins
2209 (FCGR1A)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
PDB: |
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| Position |
1q21.2
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| AA seq |
374 aa
MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNG
TATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPL
ALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAG
ISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRN
TSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVG
IMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQ
LQEGVHRKEPQGAT |
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| NT seq |
1125 nt +upstreamnt +downstreamnt
atgtggttcttgacaactctgctcctttgggttccagttgatgggcaagtggacaccaca
aaggcagtgatcactttgcagcctccatgggtcagcgtgttccaagaggaaaccgtaacc
ttgcactgtgaggtgctccatctgcctgggagcagctctacacagtggtttctcaatggc
acagccactcagacctcgacccccagctacagaatcacctctgccagtgtcaatgacagt
ggtgaatacaggtgccagagaggtctctcagggcgaagtgaccccatacagctggaaatc
cacagaggctggctactactgcaggtctccagcagagtcttcacggaaggagaacctctg
gccttgaggtgtcatgcgtggaaggataagctggtgtacaatgtgctttactatcgaaat
ggcaaagcctttaagtttttccactggaattctaacctcaccattctgaaaaccaacata
agtcacaatggcacctaccattgctcaggcatgggaaagcatcgctacacatcagcagga
atatctgtcactgtgaaagagctatttccagctccagtgctgaatgcatctgtgacatcc
ccactcctggaggggaatctggtcaccctgagctgtgaaacaaagttgctcttgcagagg
cctggtttgcagctttacttctccttctacatgggcagcaagaccctgcgaggcaggaac
acatcctctgaataccaaatactaactgctagaagagaagactctgggttatactggtgc
gaggctgccacagaggatggaaatgtccttaagcgcagccctgagttggagcttcaagtg
cttggcctccagttaccaactcctgtctggtttcatgtccttttctatctggcagtggga
ataatgtttttagtgaacactgttctctgggtgacaatacgtaaagaactgaaaagaaag
aaaaagtgggatttagaaatctctttggattctggtcatgagaagaaggtaatttccagc
cttcaagaagacagacatttagaagaagagctgaaatgtcaggaacaaaaagaagaacag
ctgcaggaaggggtgcaccggaaggagccccagggggccacgtag |
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