KEGG   Homo sapiens (human): 3249Help
Entry
3249              CDS       T01001                                 

Gene name
HPN, TMPRSS1
Definition
(RefSeq) hepsin
  KO
K08665  hepsin [EC:3.4.21.106]
Organism
hsa  Homo sapiens (human)
Pathway
hsa05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    3249 (HPN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    3249 (HPN)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.106  hepsin
     3249 (HPN)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S1: chymotrypsin family
   3249 (HPN)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Trypsin Hepsin-SRCR SRCR_2 DUF1986 Trypsin_2
Motif
Other DBs
NCBI-GeneID: 3249
NCBI-ProteinID: NP_002142
OMIM: 142440
HGNC: 5155
Ensembl: ENSG00000105707
Vega: OTTHUMG00000182474
Pharos: P05981(Tchem)
UniProt: P05981 A0A140VJK9
Structure
PDB: 

Position
19q13.11
AA seq 417 aa AA seqDB search
MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSAD
ARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCV
DEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSL
RYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYH
GGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQ
YYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCE
DSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL
NT seq 1254 nt NT seq  +upstreamnt  +downstreamnt
atggcgcagaaggagggtggccggactgtgccatgctgctccagacccaaggtggcagct
ctcactgcggggaccctgctacttctgacagccatcggggcggcatcctgggccattgtg
gctgttctcctcaggagtgaccaggagccgctgtacccagtgcaggtcagctctgcggac
gctcggctcatggtctttgacaagacggaagggacgtggcggctgctgtgctcctcgcgc
tccaacgccagggtagccggactcagctgcgaggagatgggcttcctcagggcactgacc
cactccgagctggacgtgcgaacggcgggcgccaatggcacgtcgggcttcttctgtgtg
gacgaggggaggctgccccacacccagaggctgctggaggtcatctccgtgtgtgattgc
cccagaggccgtttcttggccgccatctgccaagactgtggccgcaggaagctgcccgtg
gaccgcatcgtgggaggccgggacaccagcttgggccggtggccgtggcaagtcagcctt
cgctatgatggagcacacctctgtgggggatccctgctctccggggactgggtgctgaca
gccgcccactgcttcccggagcggaaccgggtcctgtcccgatggcgagtgtttgccggt
gccgtggcccaggcctctccccacggtctgcagctgggggtgcaggctgtggtctaccac
gggggctatcttccctttcgggaccccaacagcgaggagaacagcaacgatattgccctg
gtccacctctccagtcccctgcccctcacagaatacatccagcctgtgtgcctcccagct
gccggccaggccctggtggatggcaagatctgtaccgtgacgggctggggcaacacgcag
tactatggccaacaggccggggtactccaggaggctcgagtccccataatcagcaatgat
gtctgcaatggcgctgacttctatggaaaccagatcaagcccaagatgttctgtgctggc
taccccgagggtggcattgatgcctgccagggcgacagcggtggtccctttgtgtgtgag
gacagcatctctcggacgccacgttggcggctgtgtggcattgtgagttggggcactggc
tgtgccctggcccagaagccaggcgtctacaccaaagtcagtgacttccgggagtggatc
ttccaggccataaagactcactccgaagccagcggcatggtgacccagctctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (8)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (25)   
   RefSeq(nuc) (5)   
   GenBank (10)   
   EMBL (10)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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