KEGG   Homo sapiens (human): 3990Help
Entry
3990              CDS       T01001                                 

Gene name
LIPC, HDLCQ12, HL, HTGL, LIPH
Definition
(RefSeq) lipase C, hepatic type
  KO
K22283  hepatic triacylglycerol lipase [EC:3.1.1.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa01100  Metabolic pathways
hsa04979  Cholesterol metabolism
Module
hsa_M00098  Acylglycerol degradation
Drug target
Dextran (DG00180): D02047 D03343
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    3990 (LIPC)
 09150 Organismal Systems
  09154 Digestive system
   04979 Cholesterol metabolism
    3990 (LIPC)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.3  triacylglycerol lipase
     3990 (LIPC)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Lipase PLAT Abhydrolase_6
Motif
Other DBs
NCBI-GeneID: 3990
NCBI-ProteinID: NP_000227
OMIM: 151670
HGNC: 6619
Ensembl: ENSG00000166035
Vega: OTTHUMG00000132632
Pharos: P11150(Tbio)
UniProt: P11150 A6H8L5
Position
15q21.3
AA seq 499 aa AA seqDB search
MDTSPLCFSILLVLCIFIQSSALGQSLKPEPFGRRAQAVETNKTLHEMKTRFLLFGETNQ
GCQIRINHPDTLQECGFNSSLPLVMIIHGWSVDGVLENWIWQMVAALKSQPAQPVNVGLV
DWITLAHDHYTIAVRNTRLVGKEVAALLRWLEESVQLSRSHVHLIGYSLGAHVSGFAGSS
IGGTHKIGRITGLDAAGPLFEGSAPSNRLSPDDANFVDAIHTFTREHMGLSVGIKQPIGH
YDFYPNGGSFQPGCHFLELYRHIAQHGFNAITQTIKCSHERSVHLFIDSLLHAGTQSMAY
PCGDMNSFSQGLCLSCKKGRCNTLGYHVRQEPRSKSKRLFLVTRAQSPFKVYHYQFKIQF
INQTETPIQTTFTMSLLGTKEKMQKIPITLGKGIASNKTYSFLITLDVDIGELIMIKFKW
ENSAVWANVWDTVQTIIPWSTGPRHSGLVLKTIRVKAGETQQRMTFCSENTDDLLLRPTQ
EKIFVKCEIKSKTSKRKIR
NT seq 1500 nt NT seq  +upstreamnt  +downstreamnt
atggacacaagtcccctgtgtttctccattctgttggttttatgcatctttatccaatca
agtgcccttggacaaagcctgaaaccagagccatttggaagaagagctcaagctgttgaa
acaaacaaaacgctgcatgagatgaagaccagattcctgctctttggagaaaccaatcag
ggctgtcagattcgaatcaatcatccggacacgttacaggagtgcggcttcaactcctcc
ctgcctctggtgatgataatccacgggtggtcggtggacggcgtgctagaaaactggatc
tggcagatggtggccgcgctgaagtctcagccggcccagccagtgaacgtggggctggtg
gactggatcaccctggcccacgaccactacaccatcgccgtccgcaacacccgccttgtg
ggcaaggaggtcgcggctcttctccggtggctggaggaatctgtgcaactctctcgaagc
catgttcacctaattgggtacagcctgggtgcacacgtgtcaggatttgccggcagttcc
atcggtggaacgcacaagattgggagaatcacagggctggatgccgcgggacctttgttt
gagggaagtgcccccagcaatcgtctttctccagatgatgccaattttgtggatgccatt
catacctttacccgggagcacatgggcctgagcgtgggcatcaaacagcccataggacac
tatgacttctatcccaacgggggctccttccagcctggctgccacttcctagagctctac
agacatattgcccagcacggcttcaatgccatcacccagaccataaaatgctcccacgag
cgatcggtgcaccttttcatcgactccttgctgcacgccggcacgcagagcatggcctac
ccgtgtggtgacatgaacagcttcagccagggcctgtgcctgagctgcaagaagggccgc
tgcaacacgctgggctaccacgtccgccaggagccgcggagcaagagcaagaggctcttc
ctcgtaacgcgagcccagtcccccttcaaagtttatcattaccagttcaagatccagttc
atcaaccaaactgagacaccaatacaaacaacttttaccatgtcactactcggaacaaaa
gagaaaatgcagaaaattcccatcactctgggcaaaggaattgctagtaataaaacgtat
tcctttcttatcacgctggatgtggatatcggcgagctgatcatgatcaagttcaagtgg
gaaaacagtgcagtgtgggccaatgtctgggacacggtccagaccatcatcccatggagc
acagggccgcgccactcaggcctcgttctgaagacgatcagagtcaaagcaggagaaacc
cagcaaagaatgacattttgttcagaaaacacagatgacctactacttcgcccaacccag
gaaaaaatcttcgtgaaatgtgaaataaagtctaaaacatcaaagcgaaagatcagatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Disease (4)   
   OMIM (4)   
Drug (2)   
   KEGG DRUG (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (35)   
   RefSeq(nuc) (7)   
   GenBank (14)   
   EMBL (14)   
Protein domain (3)   
   Pfam (3)   
All databases (84)   

Download RDF
DBGET integrated database retrieval system