KEGG   Homo sapiens (human): 5000Help
Entry
5000              CDS       T01001                                 

Gene name
ORC4, ORC4L, ORC4P
Definition
(RefSeq) origin recognition complex subunit 4
  KO
K02606  origin recognition complex subunit 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Module
hsa_M00284  Origin recognition complex
Disease
H00464  Patella dysplasias
H01889  Meier-Gorlin syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Cellular Processes
  Cell growth and death
   04110 Cell cycle
    5000 (ORC4)
DNA replication proteins [BR:hsa03032]
 Eukaryotic Type
  DNA Replication Initiation Factors
   pre-RC (pre-replication complex)
    5000 (ORC4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: ORC4_C AAA_16 AAA AAA_22 ATPase_2 NACHT AAA_19 TniB AAA_14 DUF815 NB-ARC DUF2075 DAP3 T2SSE KAP_NTPase Mg_chelatase AAA_33 AAA_18 ABC_tran AAA_5 RsgA_GTPase cobW SRPRB AAA_30 AAA_24 AAA_29
Motif
Other DBs
NCBI-GeneID: 5000
NCBI-ProteinID: NP_001177808
OMIM: 603056
HGNC: 8490
Ensembl: ENSG00000115947
Vega: OTTHUMG00000131849
Pharos: O43929(Tbio)
UniProt: O43929
Structure
PDB: 

Position
2q23.1
AA seq 436 aa AA seqDB search
MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES
NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL
ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS
QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF
PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV
DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK
AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN
CPTDVRQWATSSLSWL
NT seq 1311 nt NT seq  +upstreamnt  +downstreamnt
atgagcagtcgtaaatcaaagagtaacagcttaattcacacagagtgcctttcacaggta
caaagaattttacgtgaaagattttgtcgtcagagtccacatagtaacctatttggagtg
caagtacaatacaaacacttaagtgagctgctgaaaagaactgctctccatggagagagt
aactctgtccttattatcggaccccgaggatcaggaaaaactatgttaataaatcatgct
ttgaaagaactcatggaaatagaagaagtgagtgaaaatgtattacaagttcacttaaat
ggactgctgcagatcaatgacaaaatcgccctaaaggaaatcacaaggcagttaaatctg
gaaaatgtagttggagataaagtttttggaagctttgctgaaaacctttcatttcttctg
gaagctttaaaaaaaggtgaccgaactagcagttgcccagtgatcttcatattagatgaa
tttgatctttttgctcatcataaaaaccaaacacttctctataatctttttgacatttct
cagtctgcacagaccccaatagcagttattggtcttacatgtagattggatattttggaa
ctcttagaaaaaagagtgaagtcaagattttctcaccggcagatacacttaatgaattca
tttggttttccacagtatgttaaaatatttaaagaacagttatctctacctgcagagttt
ccagacaaggtttttgctgagaagtggaatgaaaatgttcagtatctctcagaagataga
agtgtgcaagaagtactacagaagcatttcaatatcagcaaaaacctgcggtcattacac
atgctattgatgcttgctttaaatcgagtaacagcatcgcacccatttatgactgccgta
gatctaatggaagcaagccaactgtgtagcatggactcgaaagcaaatattgtacatggt
ctatcagtcttggaaatctgtcttataatagcaatgaaacatttaaatgacatctatgag
gaagagccatttaattttcaaatggtctataatgagtttcagaagtttgttcaaaggaaa
gcacattccgtttataattttgaaaaacctgttgtcatgaaggcttttgaacacttgcag
caattagaattaataaagcccatggaaagaacttcaggaaattcacagagagagtaccag
ctgatgaaactgcttttggataatactcaaattatgaatgctctgcagaaatatcccaac
tgtcctacagatgtgaggcagtgggcaacatcctcactaagctggttatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (1)   
   KEGG MODULE (1)   
Disease (4)   
   KEGG DISEASE (2)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (11)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (75)   
   RefSeq(nuc) (9)   
   GenBank (33)   
   EMBL (33)   
Protein domain (26)   
   Pfam (26)   
All databases (157)   

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