KEGG   Homo sapiens (human): 5000
Entry
5000              CDS       T01001                                 
Symbol
ORC4, ORC4L, ORC4P
Name
(RefSeq) origin recognition complex subunit 4
  KO
K02606  origin recognition complex subunit 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04110  Cell cycle
Network
nt06509  DNA replication
  Element
N01468  DNA replication licensing
N01470  Pre-IC formation
Disease
H01889  Meier-Gorlin syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    5000 (ORC4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:hsa03032]
    5000 (ORC4)
DNA replication proteins [BR:hsa03032]
 Eukaryotic type
  DNA Replication Initiation Factors
   pre-RC (pre-replication complex)
    5000 (ORC4)
SSDB
Motif
Pfam: ORC4_C AAA_16 AAA ATPase_2 AAA_22 NACHT AAA_19 TniB AAA_14 nSTAND3 DUF815 AAA_7 T2SSE DAP3 NB-ARC KAP_NTPase P-loop_TraG AAA_5 Mg_chelatase cobW SLFN-g3_helicase ABC_tran ResIII AAA_29 RsgA_GTPase nSTAND1 AAA_18 AAA_24 UvrD-helicase
Other DBs
NCBI-GeneID: 5000
NCBI-ProteinID: NP_001177808
OMIM: 603056
HGNC: 8490
Ensembl: ENSG00000115947
UniProt: O43929
Structure
Position
2:complement(147930396..148021551)
AA seq 436 aa
MSSRKSKSNSLIHTECLSQVQRILRERFCRQSPHSNLFGVQVQYKHLSELLKRTALHGES
NSVLIIGPRGSGKTMLINHALKELMEIEEVSENVLQVHLNGLLQINDKIALKEITRQLNL
ENVVGDKVFGSFAENLSFLLEALKKGDRTSSCPVIFILDEFDLFAHHKNQTLLYNLFDIS
QSAQTPIAVIGLTCRLDILELLEKRVKSRFSHRQIHLMNSFGFPQYVKIFKEQLSLPAEF
PDKVFAEKWNENVQYLSEDRSVQEVLQKHFNISKNLRSLHMLLMLALNRVTASHPFMTAV
DLMEASQLCSMDSKANIVHGLSVLEICLIIAMKHLNDIYEEEPFNFQMVYNEFQKFVQRK
AHSVYNFEKPVVMKAFEHLQQLELIKPMERTSGNSQREYQLMKLLLDNTQIMNALQKYPN
CPTDVRQWATSSLSWL
NT seq 1311 nt   +upstreamnt  +downstreamnt
atgagcagtcgtaaatcaaagagtaacagcttaattcacacagagtgcctttcacaggta
caaagaattttacgtgaaagattttgtcgtcagagtccacatagtaacctatttggagtg
caagtacaatacaaacacttaagtgagctgctgaaaagaactgctctccatggagagagt
aactctgtccttattatcggaccccgaggatcaggaaaaactatgttaataaatcatgct
ttgaaagaactcatggaaatagaagaagtgagtgaaaatgtattacaagttcacttaaat
ggactgctgcagatcaatgacaaaatcgccctaaaggaaatcacaaggcagttaaatctg
gaaaatgtagttggagataaagtttttggaagctttgctgaaaacctttcatttcttctg
gaagctttaaaaaaaggtgaccgaactagcagttgcccagtgatcttcatattagatgaa
tttgatctttttgctcatcataaaaaccaaacacttctctataatctttttgacatttct
cagtctgcacagaccccaatagcagttattggtcttacatgtagattggatattttggaa
ctcttagaaaaaagagtgaagtcaagattttctcaccggcagatacacttaatgaattca
tttggttttccacagtatgttaaaatatttaaagaacagttatctctacctgcagagttt
ccagacaaggtttttgctgagaagtggaatgaaaatgttcagtatctctcagaagataga
agtgtgcaagaagtactacagaagcatttcaatatcagcaaaaacctgcggtcattacac
atgctattgatgcttgctttaaatcgagtaacagcatcgcacccatttatgactgccgta
gatctaatggaagcaagccaactgtgtagcatggactcgaaagcaaatattgtacatggt
ctatcagtcttggaaatctgtcttataatagcaatgaaacatttaaatgacatctatgag
gaagagccatttaattttcaaatggtctataatgagtttcagaagtttgttcaaaggaaa
gcacattccgtttataattttgaaaaacctgttgtcatgaaggcttttgaacacttgcag
caattagaattaataaagcccatggaaagaacttcaggaaattcacagagagagtaccag
ctgatgaaactgcttttggataatactcaaattatgaatgctctgcagaaatatcccaac
tgtcctacagatgtgaggcagtgggcaacatcctcactaagctggttatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (2)   
   KEGG NETWORK (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (33)   
   KEGG ORTHOLOGY (1)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (78)   
   RefSeq(nuc) (12)   
   GenBank (33)   
   EMBL (33)   
3D Structure (10)   
   PDB (10)   
Protein domain (29)   
   Pfam (29)   
All databases (173)   

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