KEGG   Homo sapiens (human): 51166
Entry
51166             CDS       T01001                                 
Symbol
AADAT, KAT2, KATII, KYAT2
Name
(RefSeq) aminoadipate aminotransferase
  KO
K00825  kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00310  Lysine degradation
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
hsa01210  2-Oxocarboxylic acid metabolism
Module
hsa_M00032  Lysine degradation, lysine => saccharopine => acetoacetyl-CoA
Network
nt06036  Lysine degradation
  Element
N01685  Lysine degradation 1
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    51166 (AADAT)
   00310 Lysine degradation
    51166 (AADAT)
   00380 Tryptophan metabolism
    51166 (AADAT)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    51166 (AADAT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.7  kynurenine---oxoglutarate transaminase
     51166 (AADAT)
    2.6.1.39  2-aminoadipate transaminase
     51166 (AADAT)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   51166 (AADAT)
SSDB
Motif
Pfam: Aminotran_1_2 Asp_aminotransf
Other DBs
NCBI-GeneID: 51166
NCBI-ProteinID: NP_001273612
OMIM: 611754
HGNC: 17929
Ensembl: ENSG00000109576
UniProt: Q8N5Z0 Q4W5N8
Structure
Position
4:complement(170060222..170094292)
AA seq 425 aa
MNYARFITAASAARNPSPIRTMTDILSRGPKSMISLAGGLPNPNMFPFKTAVITVENGKT
IQFGEEMMKRALQYSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQG
LCKVFEMIINPGDNVLLDEPAYSGTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKP
EDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNK
FRVPTFLSMDVDGRVIRADSFSKIISSGLRIGFLTGPKPLIERVILHIQVSTLHPSTFNQ
LMISQLLHEWGEEGFMAHVDRVIDFYSNQKDAILAAADKWLTGLAEWHVPAAGMFLWIKV
KGINDVKELIEEKAVKMGVLMLPGNAFYVDSSAPSPYLRASFSSASPEQMDVAFQVLAQL
IKESL
NT seq 1278 nt   +upstreamnt  +downstreamnt
atgaattacgcacggttcatcacggcagcgagcgcagccagaaacccttctcccatccgg
accatgactgacatattgagcagaggaccaaaatcgatgatctccttggctggtggctta
ccaaatccaaacatgtttccttttaagactgccgtaatcactgtagaaaatggaaagacc
atccaatttggagaagagatgatgaagagagcacttcagtattctccgagtgctggaatt
ccagagcttttgtcctggctaaaacagttacaaataaaattgcataatcctcctaccatc
cattacccacccagtcaaggacaaatggatctatgtgtcacatctggcagccaacaaggt
ctttgtaaggtgtttgaaatgatcattaatcctggagataatgtcctcctagatgaacct
gcttattcaggaactcttcaaagtctgcacccactgggctgcaacattattaatgttgcc
agtgatgaaagtgggattgttccagattccctaagagacatactttccagatggaaacca
gaagatgcaaagaatccccagaaaaacacccccaaatttctttatactgttccaaatggc
aacaaccctactggaaactcattaaccagtgaacgcaaaaaggaaatctatgagcttgca
agaaaatatgatttcctcataatagaagatgatccttactattttctccagtttaacaag
ttcagggtaccaacatttctttccatggatgttgatggacgtgtcatcagagctgactct
ttttcaaaaatcatttcctctgggttgagaataggatttttaactggtccaaaaccctta
atagagagagttattttacacatacaagtttcaacattgcaccccagcacttttaaccag
ctcatgatatcacagcttctacacgaatggggagaagaaggtttcatggctcatgtagac
agggttattgatttctatagtaaccagaaggatgcaatactggcagctgcagacaagtgg
ttaactggtttggcagaatggcatgttcctgctgctggaatgtttttatggattaaagtt
aaaggcattaatgatgtaaaagaactgattgaagaaaaggccgttaagatgggggtatta
atgctccctggaaatgctttctacgtcgatagctcagctcctagcccttacttgagagca
tccttctcttcagcttctccagaacagatggatgtggccttccaggtattagcacaactt
ataaaagaatctttatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (11)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (15)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (22)   
   RefSeq(nuc) (12)   
   GenBank (5)   
   EMBL (5)   
3D Structure (17)   
   PDB (17)   
Protein domain (2)   
   Pfam (2)   
All databases (68)   

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