KEGG   Homo sapiens (human): 54878
Entry
54878             CDS       T01001                                 

Gene name
DPP8, DP8, DPRP-1, DPRP1, MST097, MSTP097, MSTP135, MSTP141
Definition
(RefSeq) dipeptidyl peptidase 8
  KO
K08655  dipeptidyl-peptidase 8 [EC:3.4.14.5]
Organism
hsa  Homo sapiens (human)
Drug target
Talabostat (DG02903): D05989 D05990
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    54878 (DPP8)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.14  Dipeptidyl-peptidases and tripeptidyl-peptidases
    3.4.14.5  dipeptidyl-peptidase IV
     54878 (DPP8)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S9: prolyl oligopeptidase family
   54878 (DPP8)
SSDB
Motif
Pfam: DPPIV_N Peptidase_S9 Peptidase_S15 Abhydrolase_1 Abhydrolase_6 Esterase
Other DBs
NCBI-GeneID: 54878
NCBI-ProteinID: NP_001307804
OMIM: 606819
HGNC: 16490
Ensembl: ENSG00000074603
Vega: OTTHUMG00000133150
Pharos: Q6V1X1(Tchem)
UniProt: Q6V1X1 A0A024R5Z6 A8K4U2
Structure
PDB: 
6EOP 6HP8 6EOO 6EOS 6EOT

Position
15q22.31
AA seq 898 aa
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQ
LKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPK
TINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISN
IVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILR
ILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVM
ERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLY
KITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYF
EGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLY
KLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGK
KYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKY
KMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAP
VTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAH
TSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI
NT seq 2697 nt   +upstreamnt  +downstreamnt
atgtggaagagatctgagcagatgaaaataaaatcaggaaaatgcaacatggcagcagca
atggaaacagaacagctgggtgttgagatatttgaaactgcggactgtgaggagaatatt
gaatcacaggatcggcctaaattggagcctttttatgttgagcggtattcctggagtcag
cttaaaaagctgcttgccgataccagaaaatatcatggctacatgatggctaaggcacca
catgatttcatgtttgtgaagaggaatgatccagatggacctcattcagacagaatctat
taccttgccatgtctggtgagaacagagaaaatacactgttttattctgaaattcccaaa
actatcaatagagcagcagtcttaatgctctcttggaagcctcttttggatctttttcag
gcaacactggactatggaatgtattctcgagaagaagaactattaagagaaagaaaacgc
attggaacagtcggaattgcttcttacgattatcaccaaggaagtggaacatttctgttt
caagccggtagtggaatttatcacgtaaaagatggagggccacaaggatttacgcaacaa
cctttaaggcccaatctagtggaaactagttgtcccaacatacggatggatccaaaatta
tgccctgctgatccagactggattgcttttatacatagcaacgatatttggatatctaac
atcgtaaccagagaagaaaggagactcacttatgtgcacaatgagctagccaacatggaa
gaagatgccagatcagctggagtcgctacctttgttctccaagaagaatttgatagatat
tctggctattggtggtgtccaaaagctgaaacaactcccagtggtggtaaaattcttaga
attctatatgaagaaaatgatgaatctgaggtggaaattattcatgttacatcccctatg
ttggaaacaaggagggcagattcattccgttatcctaaaacaggtacagcaaatcctaaa
gtcacttttaagatgtcagaaataatgattgatgctgaaggaaggatcatagatgtcata
gataaggaactaattcaaccttttgagattctatttgaaggagttgaatatattgccaga
gctggatggactcctgagggaaaatatgcttggtccatcctactagatcgctcccagact
cgcctacagatagtgttgatctcacctgaattatttatcccagtagaagatgatgttatg
gaaaggcagagactcattgagtcagtgcctgattctgtgacgccactaattatctatgaa
gaaacaacagacatctggataaatatccatgacatctttcatgtttttccccaaagtcac
gaagaggaaattgagtttatttttgcctctgaatgcaaaacaggtttccgtcatttatac
aaaattacatctattttaaaggaaagcaaatataaacgatccagtggtgggctgcctgct
ccaagtgatttcaagtgtcctatcaaagaggagatagcaattaccagtggtgaatgggaa
gttcttggccggcatggatctaatatccaagttgatgaagtcagaaggctggtatatttt
gaaggcaccaaagactcccctttagagcatcacctgtacgtagtcagttacgtaaatcct
ggagaggtgacaaggctgactgaccgtggctactcacattcttgctgcatcagtcagcac
tgtgacttctttataagtaagtatagtaaccagaagaatccacactgtgtgtccctttac
aagctatcaagtcctgaagatgacccaacttgcaaaacaaaggaattttgggccaccatt
ttggattcagcaggtcctcttcctgactatactcctccagaaattttctcttttgaaagt
actactggatttacattgtatgggatgctctacaagcctcatgatctacagcctggaaag
aaatatcctactgtgctgttcatatatggtggtcctcaggtgcagttggtgaataatcgg
tttaaaggagtcaagtatttccgcttgaataccctagcctctctaggttatgtggttgta
gtgatagacaacaggggatcctgtcaccgagggcttaaatttgaaggcgcctttaaatat
aaaatgggtcaaatagaaattgacgatcaggtggaaggactccaatatctagcttctcga
tatgatttcattgacttagatcgtgtgggcatccacggctggtcctatggaggatacctc
tccctgatggcattaatgcagaggtcagatatcttcagggttgctattgctggggcccca
gtcactctgtggatcttctatgatacaggatacacggaacgttatatgggtcaccctgac
cagaatgaacagggctattacttaggatctgtggccatgcaagcagaaaagttcccctct
gaaccaaatcgtttactgctcttacatggtttcctggatgagaatgtccattttgcacat
accagtatattactgagttttttagtgagggctggaaagccatatgatttacagatctat
cctcaggagagacacagcataagagttcctgaatcgggagaacattatgaactgcatctt
ttgcactaccttcaagaaaaccttggatcacgtattgctgctctaaaagtgatataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Drug (2)   
   KEGG DRUG (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (26)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (22)   
DNA sequence (76)   
   RefSeq(nuc) (32)   
   GenBank (22)   
   EMBL (22)   
Protein domain (6)   
   Pfam (6)   
All databases (141)   

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