KEGG   Homo sapiens (human): 54878
Entry
54878             CDS       T01001                                 
Symbol
DPP8, DP8, DPRP-1, DPRP1, MST097, MSTP097, MSTP135, MSTP141
Name
(RefSeq) dipeptidyl peptidase 8
  KO
K08655  dipeptidyl-peptidase 8 [EC:3.4.14.5]
Organism
hsa  Homo sapiens (human)
Drug target
Talabostat (DG02903): D05989 D05990
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    54878 (DPP8)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.14  Dipeptidyl-peptidases and tripeptidyl-peptidases
    3.4.14.5  dipeptidyl-peptidase IV
     54878 (DPP8)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S9: prolyl oligopeptidase family
   54878 (DPP8)
SSDB
Motif
Pfam: Dpp_8_9_N DPPIV_N Peptidase_S9 Peptidase_S15 BD-FAE Abhydrolase_1 Abhydrolase_6 PETase Esterase
Other DBs
NCBI-GeneID: 54878
NCBI-ProteinID: NP_001307804
OMIM: 606819
HGNC: 16490
Ensembl: ENSG00000074603
UniProt: Q6V1X1 A8K4U2
Structure
Position
15:complement(65442467..65517689)
AA seq 898 aa
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQ
LKKLLADTRKYHGYMMAKAPHDFMFVKRNDPDGPHSDRIYYLAMSGENRENTLFYSEIPK
TINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISN
IVTREERRLTYVHNELANMEEDARSAGVATFVLQEEFDRYSGYWWCPKAETTPSGGKILR
ILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVM
ERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEEIEFIFASECKTGFRHLY
KITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNIQVDEVRRLVYF
EGTKDSPLEHHLYVVSYVNPGEVTRLTDRGYSHSCCISQHCDFFISKYSNQKNPHCVSLY
KLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEIFSFESTTGFTLYGMLYKPHDLQPGK
KYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASLGYVVVVIDNRGSCHRGLKFEGAFKY
KMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWSYGGYLSLMALMQRSDIFRVAIAGAP
VTLWIFYDTGYTERYMGHPDQNEQGYYLGSVAMQAEKFPSEPNRLLLLHGFLDENVHFAH
TSILLSFLVRAGKPYDLQIYPQERHSIRVPESGEHYELHLLHYLQENLGSRIAALKVI
NT seq 2697 nt   +upstreamnt  +downstreamnt
atgtggaagagatctgagcagatgaaaataaaatcaggaaaatgcaacatggcagcagca
atggaaacagaacagctgggtgttgagatatttgaaactgcggactgtgaggagaatatt
gaatcacaggatcggcctaaattggagcctttttatgttgagcggtattcctggagtcag
cttaaaaagctgcttgccgataccagaaaatatcatggctacatgatggctaaggcacca
catgatttcatgtttgtgaagaggaatgatccagatggacctcattcagacagaatctat
taccttgccatgtctggtgagaacagagaaaatacactgttttattctgaaattcccaaa
actatcaatagagcagcagtcttaatgctctcttggaagcctcttttggatctttttcag
gcaacactggactatggaatgtattctcgagaagaagaactattaagagaaagaaaacgc
attggaacagtcggaattgcttcttacgattatcaccaaggaagtggaacatttctgttt
caagccggtagtggaatttatcacgtaaaagatggagggccacaaggatttacgcaacaa
cctttaaggcccaatctagtggaaactagttgtcccaacatacggatggatccaaaatta
tgccctgctgatccagactggattgcttttatacatagcaacgatatttggatatctaac
atcgtaaccagagaagaaaggagactcacttatgtgcacaatgagctagccaacatggaa
gaagatgccagatcagctggagtcgctacctttgttctccaagaagaatttgatagatat
tctggctattggtggtgtccaaaagctgaaacaactcccagtggtggtaaaattcttaga
attctatatgaagaaaatgatgaatctgaggtggaaattattcatgttacatcccctatg
ttggaaacaaggagggcagattcattccgttatcctaaaacaggtacagcaaatcctaaa
gtcacttttaagatgtcagaaataatgattgatgctgaaggaaggatcatagatgtcata
gataaggaactaattcaaccttttgagattctatttgaaggagttgaatatattgccaga
gctggatggactcctgagggaaaatatgcttggtccatcctactagatcgctcccagact
cgcctacagatagtgttgatctcacctgaattatttatcccagtagaagatgatgttatg
gaaaggcagagactcattgagtcagtgcctgattctgtgacgccactaattatctatgaa
gaaacaacagacatctggataaatatccatgacatctttcatgtttttccccaaagtcac
gaagaggaaattgagtttatttttgcctctgaatgcaaaacaggtttccgtcatttatac
aaaattacatctattttaaaggaaagcaaatataaacgatccagtggtgggctgcctgct
ccaagtgatttcaagtgtcctatcaaagaggagatagcaattaccagtggtgaatgggaa
gttcttggccggcatggatctaatatccaagttgatgaagtcagaaggctggtatatttt
gaaggcaccaaagactcccctttagagcatcacctgtacgtagtcagttacgtaaatcct
ggagaggtgacaaggctgactgaccgtggctactcacattcttgctgcatcagtcagcac
tgtgacttctttataagtaagtatagtaaccagaagaatccacactgtgtgtccctttac
aagctatcaagtcctgaagatgacccaacttgcaaaacaaaggaattttgggccaccatt
ttggattcagcaggtcctcttcctgactatactcctccagaaattttctcttttgaaagt
actactggatttacattgtatgggatgctctacaagcctcatgatctacagcctggaaag
aaatatcctactgtgctgttcatatatggtggtcctcaggtgcagttggtgaataatcgg
tttaaaggagtcaagtatttccgcttgaataccctagcctctctaggttatgtggttgta
gtgatagacaacaggggatcctgtcaccgagggcttaaatttgaaggcgcctttaaatat
aaaatgggtcaaatagaaattgacgatcaggtggaaggactccaatatctagcttctcga
tatgatttcattgacttagatcgtgtgggcatccacggctggtcctatggaggatacctc
tccctgatggcattaatgcagaggtcagatatcttcagggttgctattgctggggcccca
gtcactctgtggatcttctatgatacaggatacacggaacgttatatgggtcaccctgac
cagaatgaacagggctattacttaggatctgtggccatgcaagcagaaaagttcccctct
gaaccaaatcgtttactgctcttacatggtttcctggatgagaatgtccattttgcacat
accagtatattactgagttttttagtgagggctggaaagccatatgatttacagatctat
cctcaggagagacacagcataagagttcctgaatcgggagaacattatgaactgcatctt
ttgcactaccttcaagaaaaccttggatcacgtattgctgctctaaaagtgatataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (22)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (61)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (58)   
DNA sequence (110)   
   RefSeq(nuc) (66)   
   GenBank (22)   
   EMBL (22)   
3D Structure (19)   
   PDB (19)   
Protein domain (9)   
   Pfam (9)   
All databases (222)   

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