KEGG   Homo sapiens (human): 6091
Entry
6091              CDS       T01001                                 

Symbol
ROBO1, DUTT1, SAX3
Name
(RefSeq) roundabout guidance receptor 1
  KO
K06753  roundabout, axon guidance receptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04360  Axon guidance
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04360 Axon guidance
    6091 (ROBO1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04515 Cell adhesion molecules [BR:hsa04515]
    6091 (ROBO1)
Cell adhesion molecules [BR:hsa04515]
 Immunoglobulin superfamily
  ROBO family
   6091 (ROBO1)
SSDB
Motif
Pfam: I-set Ig_3 Ig_2 ig fn3 V-set C2-set_2 Pur_ac_phosph_N
Other DBs
NCBI-GeneID: 6091
NCBI-ProteinID: NP_002932
OMIM: 602430
HGNC: 10249
Ensembl: ENSG00000169855
Vega: OTTHUMG00000158843
Pharos: Q9Y6N7(Tbio)
UniProt: Q9Y6N7
Structure
PDB: 

Position
3p12.3
AA seq 1651 aa
MKWKHVPFLVMISLLSLSPNHLFLAQLIPDPEDVERGNDHGTPIPTSDNDDNSLGYTGSR
LRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRM
LLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVM
VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC
VGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDG
ELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQ
VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQR
SDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATG
SPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYI
EVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATPTSYIIEAFS
HASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDPVKTQDVLPT
SQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGE
SDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQ
GVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIP
FLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGNPVSPEDQVSLAQQISDVVKQPAFI
AGIGAACWIILMVFSIWLYRHRKKRNGLTSTYAGIRKVPSFTFTPTVTYQRGGEAVSSGG
RPGLLNISEPAAQPWLADTWPNTGNNHNDCSISCCTAGNGNSDSNLTTYSRPADCIANYN
NQLDNKQTNLMLPESTVYGDVDLSNKINEMKTFNSPNLKDGRFVNPSGQPTPYATTQLIQ
SNLSNNMNNGSGDSGEKHWKPLGQQKQEVAPVQYNIVEQNKLNKDYRANDTVPPTIPYNQ
SYDQNTGGSYNSSDRGSSTSGSQGHKKGARTPKVPKQGGMNWADLLPPPPAHPPPHSNSE
EYNISVDESYDQEMPCPVPPARMYLQQDELEEEEDERGPTPPVRGAASSPAAVSYSHQST
ATLTPSPQEELQPMLQDCPEETGHMQHQPDRRRQPVSPPPPPRPISPPHTYGYISGPLVS
DMDTDAPEEEEDEADMEVAKMQTRRLLLRGLEQTPASSVGDLESSVTGSMINGWGSASEE
DNISSGRSSVSSSDGSFFTDADFAQAVAAAAEYAGLKVARRQMQDAAGRRHFHASQCPRP
TSPVSTDSNMSAAVMQKTRPAKKLKHQPGHLRRETYTDDLPPPPVPPPAIKSPTAQSKTQ
LEVRPVVVPKLPSMDARTDRSSDRKGSSYKGREVLDGRQVVDMRTNPGDPREAQEQQNDG
KGRGNKAAKRDLPPAKTHLIQEDILPYCRPTFPTSNNPRDPSSSSSMSSRGSGSRQREQA
NVGRRNIAEMQVLGGYERGEDNNEELEETES
NT seq 4956 nt   +upstreamnt  +downstreamnt
atgaaatggaaacatgttccttttttggtcatgatatcactcctcagcttatccccaaat
cacctgtttctggcccagcttattccagaccctgaagatgtagagagggggaacgaccac
gggacgccaatccccacctctgataacgatgacaattcgctgggctatacaggctcccgt
cttcgtcaggaagattttccacctcgcattgttgaacacccttcagacctgattgtctca
aaaggagaacctgcaactttgaactgcaaagctgaaggccgccccacacccactattgaa
tggtacaaagggggagagagagtggagacagacaaagatgaccctcgctcacaccgaatg
ttgctgccgagtggatctttatttttcttacgtatagtacatggacggaaaagtagacct
gatgaaggagtctatgtctgtgtagcaaggaattaccttggagaggctgtgagccacaat
gcatcgctggaagtagccatacttcgggatgacttcagacaaaacccttcggatgtcatg
gttgcagtaggagagcctgcagtaatggaatgccaacctccacgaggccatcctgagccc
accatttcatggaagaaagatggctctccactggatgataaagatgaaagaataactata
cgaggaggaaagctcatgatcacttacacccgtaaaagtgacgctggcaaatatgtttgt
gttggtaccaatatggttggggaacgtgagagtgaagtagccgagctgactgtcttagag
agaccatcatttgtgaagagacccagtaacttggcagtaactgtggatgacagtgcagaa
tttaaatgtgaggcccgaggtgaccctgtacctacagtacgatggaggaaagatgatgga
gagctgcccaaatccagatatgaaatccgagatgatcataccttgaaaattaggaaggtg
acagctggtgacatgggttcatacacttgtgttgcagaaaatatggtgggcaaagctgaa
gcatctgctactctgactgttcaagaacctccacattttgttgtgaaaccccgtgaccag
gttgttgctttgggacggactgtaacttttcagtgtgaagcaaccggaaatcctcaacca
gctattttctggaggagagaagggagtcagaatctacttttctcatatcaaccaccacag
tcatccagccgattttcagtctcccagactggcgacctcacaattactaatgtccagcga
tctgatgttggttattacatctgccagactttaaatgttgctggaagcatcatcacaaag
gcatatttggaagttacagatgtgattgcagatcggcctcccccagttattcgacaaggt
cctgtgaatcagactgtagccgtggatggcactttcgtcctcagctgtgtggccacaggc
agtccagtgcccaccattctgtggagaaaggatggagtcctcgtttcaacccaagactct
cgaatcaaacagttggagaatggagtactgcagatccgatatgctaagctgggtgatact
ggtcggtacacctgcattgcatcaacccccagtggtgaagcaacatggagtgcttacatt
gaagttcaagaatttggagttccagttcagcctccaagacctactgacccaaatttaatc
cctagtgccccatcaaaacctgaagtgacagatgtcagcagaaatacagtcacattatcg
tggcaaccaaatttgaattcaggagcaactccaacatcttatattatagaagccttcagc
catgcatctggtagcagctggcagaccgtagcagagaatgtgaaaacagaaacatctgcc
attaaaggactcaaacctaatgcaatttaccttttccttgtgagggcagctaatgcatat
ggaattagtgatccaagccaaatatcagatccagtgaaaacacaagatgtcctaccaaca
agtcagggggtggaccacaagcaggtccagagagagctgggaaatgctgttctgcacctc
cacaaccccaccgtcctttcttcctcttccatcgaagtgcactggacagtagatcaacag
tctcagtatatacaaggatataaaattctctatcggccatctggagccaaccacggagaa
tcagactggttagtttttgaagtgaggacgccagccaaaaacagtgtggtaatccctgat
ctcagaaagggagtcaactatgaaattaaggctcgccctttttttaatgaatttcaagga
gcagatagtgaaatcaagtttgccaaaaccctggaagaagcacccagtgccccaccccaa
ggtgtaactgtatccaagaatgatggaaacggaactgcaattctagttagttggcagcca
cctccagaagacactcaaaatggaatggtccaagagtataaggtttggtgtctgggcaat
gaaactcgataccacatcaacaaaacagtggatggttccaccttttccgtggtcattccc
tttcttgttcctggaatccgatacagtgtggaagtggcagccagcactggggctgggtct
ggggtaaagagtgagcctcagttcatccagctggatgcccatggaaaccctgtgtcacct
gaggaccaagtcagcctcgctcagcagatttcagatgtggtgaagcagccggccttcata
gcaggtattggagcagcctgttggatcatcctcatggtcttcagcatctggctttatcga
caccgcaagaagagaaacggacttactagtacctacgcgggtatcagaaaagtcccgtct
tttaccttcacaccaacagtaacttaccagagaggaggcgaagctgtcagcagtggaggg
aggcctggacttctcaacatcagtgaacctgccgcgcagccatggctggcagacacgtgg
cctaatactggcaacaaccacaatgactgctccatcagctgctgcacggcaggcaatgga
aacagcgacagcaacctcactacctacagtcgcccagctgattgtatagcaaattataac
aaccaactggataacaaacaaacaaatctgatgctccctgagtcaactgtttatggtgat
gtggaccttagtaacaaaatcaatgagatgaaaaccttcaatagcccaaatctgaaggat
gggcgttttgtcaatccatcagggcagcctactccttacgccaccactcagctcatccag
tcaaacctcagcaacaacatgaacaatggcagcggggactctggcgagaagcactggaaa
ccactgggacagcagaaacaagaagtggcaccagttcagtacaacatcgtggagcaaaac
aagctgaacaaagattatcgagcaaatgacacagttcctccaactatcccatacaaccaa
tcatacgaccagaacacaggaggatcctacaacagctcagaccggggcagtagtacatct
gggagtcaggggcacaagaaaggggcaagaacacccaaggtaccaaaacagggtggcatg
aactgggcagacctgcttcctcctcccccagcacatcctcctccacacagcaatagcgaa
gagtacaacatttctgtagatgaaagctatgaccaagaaatgccatgtcccgtgccacca
gcaaggatgtatttgcaacaagatgaattagaagaggaggaagatgaacgaggccccact
ccccctgttcggggagcagcttcttctccagctgccgtgtcctatagccatcagtccact
gccactctgactccctccccacaggaagaactccagcccatgttacaggattgtccagag
gagactggccacatgcagcaccagcccgacaggagacggcagcctgtgagtcctcctcca
ccaccacggccgatctcccctccacatacctatggctacatttcaggacccctggtctca
gatatggatacggatgcgccagaagaggaagaagacgaagccgacatggaggtagccaag
atgcaaaccagaaggcttttgttacgtgggcttgagcagacacctgcctccagtgttggg
gacctggagagctctgtcacggggtccatgatcaacggctggggctcagcctcagaggag
gacaacatttccagcggacgctccagtgttagttcttcggacggctcctttttcactgat
gctgactttgcccaggcagtcgcagcagcggcagagtatgctggtctgaaagtagcacga
cggcaaatgcaggatgctgctggccgtcgacattttcatgcgtctcagtgccctaggccc
acaagtcccgtgtctacagacagcaacatgagtgccgccgtaatgcagaaaaccagacca
gccaagaaactgaaacaccagccaggacatctgcgcagagaaacctacacagatgatctt
ccaccacctcctgtgccgccacctgctataaagtcacctactgcccaatccaagacacag
ctggaagtacgacctgtagtggtgccaaaactcccttctatggatgcaagaacagacaga
tcatcagacagaaaaggaagcagttacaaggggagagaagtgttggatggaagacaggtt
gttgacatgcgaacaaatccaggtgatcccagagaagcacaggaacagcaaaatgacggg
aaaggacgtggaaacaaggcagcaaaacgagaccttccaccagcaaagactcatctcatc
caagaggatattctaccttattgtagacctacttttccaacatcaaataatcccagagat
cccagttcctcaagctcaatgtcatcaagaggatcaggaagcagacaaagagaacaagca
aatgtaggtcgaagaaatattgcagaaatgcaggtacttggaggatatgaaagaggagaa
gataataatgaagaattagaggaaactgaaagctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (43)   
   RefSeq(nuc) (13)   
   GenBank (15)   
   EMBL (15)   
Protein domain (8)   
   Pfam (8)   
All databases (94)   

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