KEGG   Homo sapiens (human): 635
Entry
635               CDS       T01001                                 
Symbol
BHMT, BHMT1, HEL-S-61p
Name
(RefSeq) betaine--homocysteine S-methyltransferase
  KO
K00544  betaine-homocysteine S-methyltransferase [EC:2.1.1.5]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00270  Cysteine and methionine metabolism
hsa00670  One carbon pool by folate
hsa01100  Metabolic pathways
hsa04981  Folate transport and metabolism
Module
hsa_M00974  Betaine metabolism, animals, betaine => glycine
Network
nt06030  Methionine metabolism
nt06033  Glycine, serine and arginine metabolism
nt06038  Folate metabolism
  Element
N01630  Remethylation, Hcy to Met
N01789  Betaine metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    635 (BHMT)
   00270 Cysteine and methionine metabolism
    635 (BHMT)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    635 (BHMT)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    635 (BHMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.5  betaine---homocysteine S-methyltransferase
     635 (BHMT)
SSDB
Motif
Pfam: S-methyl_trans
Other DBs
NCBI-GeneID: 635
NCBI-ProteinID: NP_001704
OMIM: 602888
HGNC: 1047
Ensembl: ENSG00000145692
UniProt: Q93088 V9HWA4
Structure
Position
5:79111809..79132288
AA seq 406 aa
MPPVGGKKAKKGILERLNAGEIVIGDGGFVFALEKRGYVKAGPWTPEAAVEHPEAVRQLH
REFLRAGSNVMQTFTFYASEDKLENRGNYVLEKISGQEVNEAACDIARQVADEGDALVAG
GVSQTPSYLSCKSETEVKKVFLQQLEVFMKKNVDFLIAEYFEHVEEAVWAVETLIASGKP
VAATMCIGPEGDLHGVPPGECAVRLVKAGASIIGVNCHFDPTISLKTVKLMKEGLEAARL
KAHLMSQPLAYHTPDCNKQGFIDLPEFPFGLEPRVATRWDIQKYAREAYNLGVRYIGGCC
GFEPYHIRAIAEELAPERGFLPPASEKHGSWGSGLDMHTKPWVRARARKEYWENLRIASG
RPYNPSMSKPDGWGVTKGTAELMQQKEATTEQQLKELFEKQKFKSQ
NT seq 1221 nt   +upstreamnt  +downstreamnt
atgccacccgttgggggcaaaaaggccaagaagggcatcctagaacgtttaaatgctgga
gagattgtgattggagatggagggtttgtctttgcactggagaagaggggctacgtaaag
gcaggaccctggactcctgaagctgctgtggagcacccagaagcagttcgccagcttcat
cgagagttcctcagagctggctcaaacgtcatgcagaccttcaccttctatgcgagtgaa
gacaagctggagaacaggggcaactatgtcttagagaagatatctgggcaggaagtcaat
gaagctgcttgcgacatcgcccgacaagtggctgatgaaggagatgctttggtagcagga
ggagtgagtcagacaccttcataccttagctgcaagagtgaaactgaagtcaaaaaagta
tttctgcaacagttagaggtctttatgaagaagaacgtggacttcttgattgcagagtat
tttgaacacgttgaagaagctgtgtgggcagttgaaaccttgatagcatccggtaaacct
gtggcagcaaccatgtgcattggcccagaaggagatttgcatggcgtgccccccggcgag
tgtgcagtgcgcctggtgaaagcaggagcatccatcattggtgtgaactgccactttgac
cccaccattagtttaaaaacagtgaagctcatgaaggagggcttggaggctgcccgactg
aaagctcacctgatgagccagcccttggcttaccacactcctgactgcaacaagcaggga
ttcatcgatctcccagaattcccatttggactggaacccagagttgccaccagatgggat
attcaaaaatacgccagagaggcctacaacctgggggtcaggtacattggcgggtgctgt
ggatttgagccctaccacatcagggcaattgcagaggagctggccccagaaaggggcttt
ttgccaccagcttcagaaaaacatggcagctggggaagtggtttggacatgcacaccaaa
ccctgggttagagcaagggccaggaaggaatactgggagaatcttcggatagcctcaggc
cggccatacaacccttcaatgtcaaagccagatggctggggagtgaccaaaggaacagcc
gagctgatgcagcagaaagaagccacaactgagcagcagctgaaagagctctttgaaaaa
caaaaattcaaatcacagtag

  All links  
Disease (1)   
   OMIM (1)   
Gene (11)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (18)   
   RefSeq(nuc) (2)   
   GenBank (8)   
   EMBL (8)   
3D Structure (4)   
   PDB (4)   
Protein domain (1)   
   Pfam (1)   
All databases (40)   

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