KEGG   Homo sapiens (human): 6653
Entry
6653              CDS       T01001                                 

Gene name
SORL1, C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
Definition
(RefSeq) sortilin related receptor 1
Organism
hsa  Homo sapiens (human)
SSDB
Motif
Pfam: Sortilin-Vps10 Ldl_recept_a Sortilin_C fn3 Ldl_recept_b Pur_ac_phosph_N Interfer-bind DUF4945 BNR_6
Other DBs
NCBI-GeneID: 6653
NCBI-ProteinID: NP_003096
OMIM: 602005
HGNC: 11185
Ensembl: ENSG00000137642
Vega: OTTHUMG00000166057
Pharos: Q92673(Tbio)
UniProt: Q92673 A0A024R3H2
Structure
PDB: 
3WSX 3WSY 3WSZ 2DM4

Position
11q24.1
AA seq 2214 aa
MATRSSRRESRLPFLFTLVALLPPGALCEVWTQRLHGGSAPLPQDRGFLVVQGDPRELRL
WARGDARGASRADEKPLRRKRSAALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVAL
ARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFA
DAYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQT
WIMIQEHVKSFSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDF
QLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVF
VCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGL
QGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQR
LSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYY
TWGDHGGIITAIAQGMETNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIF
GSNKENVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATC
FNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGS
TYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATE
QLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFE
PLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKP
GIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNL
PHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNA
CVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLR
NQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDL
EDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCE
ASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLR
DCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPE
FHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGH
CIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDG
YRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDG
RDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQN
LQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKVLKPD
TTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWAPPIHTH
GLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSI
TTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRG
SILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVEC
TWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSS
DYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSY
KVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVL
LFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQAR
CLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYT
KHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA
NT seq 6645 nt   +upstreamnt  +downstreamnt
atggcgacacggagcagcaggagggagtcgcgactcccgttcctattcaccctggtcgca
ctgctgccgcccggagctctctgcgaagtctggacgcagaggctgcacggcggcagcgcg
cccttgccccaggaccggggcttcctcgtggtgcagggcgacccgcgcgagctgcggctg
tgggcgcgcggggatgccaggggggcgagccgcgcggacgagaagccgctccggaggaaa
cggagcgctgccctgcagcccgagcccatcaaggtgtacggacaggttagtctgaatgat
tcccacaatcagatggtggtgcactgggctggagagaaaagcaacgtgatcgtggccttg
gcccgagatagcctggcattggcgaggcccaagagcagtgatgtgtacgtgtcttacgac
tatggaaaatcattcaagaaaatttcagacaagttaaactttggcttgggaaataggagt
gaagctgttatcgcccagttctaccacagccctgcggacaacaagcggtacatctttgca
gacgcttatgcccagtacctctggatcacgtttgacttctgcaacactcttcaaggcttt
tccatcccatttcgggcagctgatctcctcctacacagtaaggcctccaaccttctcttg
ggctttgacaggtcccaccccaacaagcagctgtggaagtcagatgactttggccagacc
tggatcatgattcaggaacatgtcaagtccttttcttggggaattgatccctatgacaaa
ccaaataccatctacattgaacgacatgaaccctctggctactccactgtcttccgaagt
acagatttcttccagtcccgggaaaaccaggaagtgatccttgaggaagtgagagatttt
cagcttcgggacaagtacatgtttgctacaaaggtggtgcatctcttgggcagtgaacag
cagtcttctgtccagctctgggtctcctttggccggaagcccatgagagcagcccagttt
gtcacaagacatcctattaatgaatattacatcgcagatgcctccgaggaccaggtgttt
gtgtgtgtcagccacagtaacaaccgcaccaatttatacatctcagaggcagaggggctg
aagttctccctgtccttggagaacgtgctctattacagcccaggaggggccggcagtgac
accttggtgaggtattttgcaaatgaaccatttgctgacttccaccgagtggaaggattg
caaggagtctacattgctactctgattaatggttctatgaatgaggagaacatgagatcg
gtcatcacctttgacaaagggggaacctgggagtttcttcaggctccagccttcacggga
tatggagagaaaatcaattgtgagctttcccagggctgttcccttcatctggctcagcgc
ctcagtcagctcctcaacctccagctccggagaatgcccatcctgtccaaggagtcggct
ccaggcctcatcatcgccactggctcagtgggaaagaacttggctagcaagacaaacgtg
tacatctctagcagtgctggagccaggtggcgagaggcacttcctggacctcactactac
acatggggagaccacggcggaatcatcacggccattgcccagggcatggaaaccaacgag
ctaaaatacagtaccaatgaaggggagacctggaaaacattcatcttctctgagaagcca
gtgtttgtgtatggcctcctcacagaacctggggagaagagcactgtcttcaccatcttt
ggctcgaacaaagagaatgtccacagctggctgatcctccaggtcaatgccacggatgcc
ttgggagttccctgcacagagaatgactacaagctgtggtcaccatctgatgagcggggg
aatgagtgtttgctgggacacaagactgttttcaaacggcggaccccccatgccacatgc
ttcaatggagaggactttgacaggccggtggtcgtgtccaactgctcctgcacccgggag
gactatgagtgtgacttcggtttcaagatgagtgaagatttgtcattagaggtttgtgtt
ccagatccggaattttctggaaagtcatactcccctcctgtgccttgccctgtgggttct
acttacaggagaacgagaggctaccggaagatttctggggacacttgtagcggaggagat
gttgaagcgcgactggaaggagagctggtcccctgtcccctggcagaagagaacgagttc
attctgtatgctgtgaggaaatccatctaccgctatgacctggcctcgggagccaccgag
cagttgcctctcaccgggctacgggcagcagtggccctggactttgactatgagcacaac
tgtttgtattggtccgacctggccttggacgtcatccagcgcctctgtttgaatggaagc
acagggcaagaggtgatcatcaattctggcctggagacagtagaagctttggcttttgaa
cccctcagccagctgctttactgggtagatgcaggcttcaaaaagattgaggtagctaat
ccagatggcgacttccgactcacaatcgtcaattcctctgtgcttgatcgtcccagggct
ctggtcctcgtgccccaagagggggtgatgttctggacagactggggagacctgaagcct
gggatttatcggagcaatatggatggttctgctgcctatcacctggtgtctgaggatgtg
aagtggcccaatggcatctctgtggacgaccagtggatttactggacggatgcctacctg
gagtgcatagagcggatcacgttcagtggccagcagcgctctgtcattctggacaacctc
ccgcacccctatgccattgctgtctttaagaatgaaatctactgggatgactggtcacag
ctcagcatattccgagcttccaaatacagtgggtcccagatggagattctggcaaaccag
ctcacggggctcatggacatgaagattttctacaaggggaagaacactggaagcaatgcc
tgtgtgcccaggccatgcagcctgctgtgcctgcccaaggccaacaacagtagaagctgc
aggtgtccagaggatgtgtccagcagtgtgcttccatcaggggacctgatgtgtgactgc
cctcagggctatcagctcaagaacaatacctgtgtcaaacaagagaacacctgtcttcgc
aaccagtatcgctgcagcaacgggaactgtatcaacagcatttggtggtgtgactttgac
aacgactgtggagacatgagcgatgagagaaactgccctaccaccatctgtgacctggac
acccagtttcgttgccaggagtctgggacttgtatcccactgtcctataaatgtgacctt
gaggatgactgtggagacaacagtgatgaaagtcattgtgaaatgcaccagtgccggagt
gacgagtacaactgcagttccggcatgtgcatccgctcctcctgggtatgtgacggggac
aacgactgcagggactggtctgatgaagccaactgtaccgccatctatcacacctgtgag
gcctccaacttccagtgccgaaacgggcactgcatcccccagcggtgggcgtgtgacggg
gatacggactgccaggatggttccgatgaggatccagtcaactgtgagaagaagtgcaat
ggattccgctgcccaaacggcacttgcatcccatccagcaaacattgtgatggtctgcgt
gattgctctgatggctccgatgaacagcactgcgagcccctctgtacgcacttcatggac
tttgtgtgtaagaaccgccagcagtgcctgttccactccatggtctgtgacggaatcatc
cagtgccgcgacgggtccgatgaggatgcggcgtttgcaggatgctcccaagatcctgag
ttccacaaggtatgtgatgagttcggtttccagtgtcagaatggagtgtgcatcagtttg
atttggaagtgcgacgggatggatgattgcggcgattattctgatgaagccaactgcgaa
aaccccacagaagccccaaactgctcccgctacttccagtttcggtgtgagaatggccac
tgcatccccaacagatggaaatgtgacagggagaacgactgtggggactggtctgatgag
aaggattgtggagattcacatattcttcccttctcgactcctgggccctccacgtgtctg
cccaattactaccgctgcagcagtgggacctgcgtgatggacacctgggtgtgcgacggg
taccgagattgtgcagatggctctgacgaggaagcctgccccttgcttgcaaacgtcact
gctgcctccactcccacccaacttgggcgatgtgaccgatttgagttcgaatgccaccaa
ccgaagacgtgtattcccaactggaagcgctgtgacggccaccaagattgccaggatggc
cgggacgaggccaattgccccacacacagcaccttgacttgcatgagcagggagttccag
tgcgaggacggggaggcctgcattgtgctctcggagcgctgcgacggcttcctggactgc
tcggacgagagcgatgaaaaggcctgcagtgatgagttgactgtgtacaaagtacagaat
cttcagtggacagctgacttctctggggatgtgactttgacctggatgaggcccaaaaaa
atgccctctgcttcttgtgtatataatgtctactacagggtggttggagagagcatatgg
aagactctggagacccacagcaataagacaaacactgtattaaaagtcttgaaaccagat
accacgtatcaggttaaagtacaggttcagtgtctcagcaaggcacacaacaccaatgac
tttgtgaccctgaggaccccagagggattgccagatgcccctcgaaatctccagctgtca
ctccccagggaagcagaaggtgtgattgtaggccactgggctcctcccatccacacccat
ggcctcatccgtgagtacattgtagaatacagcaggagtggttccaagatgtgggcctcc
cagagggctgctagtaactttacagaaatcaagaacttattggtcaacactctatacacc
gtcagagtggctgcggtgactagtcgtggaataggaaactggagcgattctaaatccatt
accaccataaaaggaaaagtgatcccaccaccagatatccacattgacagctatggtgaa
aattatctaagcttcaccctgaccatggagagtgatatcaaggtgaatggctatgtggtg
aaccttttctgggcatttgacacccacaagcaagagaggagaactttgaacttccgagga
agcatattgtcacacaaagttggcaatctgacagctcatacatcctatgagatttctgcc
tgggccaagactgacttgggggatagccctctggcatttgagcatgttatgaccagaggg
gttcgcccacctgcacctagcctcaaggccaaagccatcaaccagactgcagtggaatgt
acctggaccggcccccggaatgtggtttatggtattttctatgccacgtcctttcttgac
ctctatcgcaacccgaagagcttgactacttcactccacaacaagacggtcattgtcagt
aaggatgagcagtatttgtttctggtccgtgtagtggtaccctaccaggggccatcctct
gactacgttgtagtgaagatgatcccggacagcaggcttccaccccgtcacctgcatgtg
gttcatacgggcaaaacctccgtggtcatcaagtgggaatcaccgtatgactctcctgac
caggacttgttgtatgcagttgcagtcaaagatctcataagaaagactgacaggagctac
aaagtaaaatcccgtaacagcactgtggaatacacccttaacaagttggagcctggcggg
aaataccacatcattgtccaactggggaacatgagcaaagattccagcataaaaattacc
acagtttcattatcagcacctgatgccttaaaaatcataacagaaaatgatcatgttctt
ctgttttggaaaagcctggctttaaaggaaaagcattttaatgaaagcaggggctatgag
atacacatgtttgatagtgccatgaatatcacagcttaccttgggaatactactgacaat
ttctttaaaatttccaacctgaagatgggtcataattacacgttcaccgtccaagcaaga
tgcctttttggcaaccagatctgtggggagcctgccatcctgctgtacgatgagctgggg
tctggtgcagatgcatctgcaacgcaggctgccagatctacggatgttgctgctgtggtg
gtgcccatcttattcctgatactgctgagcctgggggtggggtttgccatcctgtacacg
aagcaccggaggctgcagagcagcttcaccgccttcgccaacagccactacagctccagg
ctggggtccgcaatcttctcctctggggatgacctgggggaagatgatgaagatgcccct
atgataactggattttcagatgacgtccccatggtgatagcctga

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Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
Protein domain (9)   
   Pfam (9)   
All databases (85)   

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