KEGG   Homo sapiens (human): 6653
Entry
6653              CDS       T01001                                 
Symbol
SORL1, C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
Name
(RefSeq) sortilin related receptor 1
  KO
K24498  sortilin-related receptor
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    6653 (SORL1)
Membrane trafficking [BR:hsa04131]
 Endosome - Golgi transport
  Others
   Others
    6653 (SORL1)
SSDB
Motif
Pfam: Ldl_recept_a Sortilin-Vps10 Sortilin_C fn3 Ldl_recept_b Pur_ac_phosph_N Ig_DSCAM-DSCAML_C Interfer-bind BNR_6 DUF4945
Other DBs
NCBI-GeneID: 6653
NCBI-ProteinID: NP_003096
OMIM: 602005
HGNC: 11185
Ensembl: ENSG00000137642
UniProt: Q92673
Structure
Position
11:121452314..121633763
AA seq 2214 aa
MATRSSRRESRLPFLFTLVALLPPGALCEVWTQRLHGGSAPLPQDRGFLVVQGDPRELRL
WARGDARGASRADEKPLRRKRSAALQPEPIKVYGQVSLNDSHNQMVVHWAGEKSNVIVAL
ARDSLALARPKSSDVYVSYDYGKSFKKISDKLNFGLGNRSEAVIAQFYHSPADNKRYIFA
DAYAQYLWITFDFCNTLQGFSIPFRAADLLLHSKASNLLLGFDRSHPNKQLWKSDDFGQT
WIMIQEHVKSFSWGIDPYDKPNTIYIERHEPSGYSTVFRSTDFFQSRENQEVILEEVRDF
QLRDKYMFATKVVHLLGSEQQSSVQLWVSFGRKPMRAAQFVTRHPINEYYIADASEDQVF
VCVSHSNNRTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGL
QGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQR
LSQLLNLQLRRMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYY
TWGDHGGIITAIAQGMETNELKYSTNEGETWKTFIFSEKPVFVYGLLTEPGEKSTVFTIF
GSNKENVHSWLILQVNATDALGVPCTENDYKLWSPSDERGNECLLGHKTVFKRRTPHATC
FNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCVPDPEFSGKSYSPPVPCPVGS
TYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAVRKSIYRYDLASGATE
QLPLTGLRAAVALDFDYEHNCLYWSDLALDVIQRLCLNGSTGQEVIINSGLETVEALAFE
PLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKP
GIYRSNMDGSAAYHLVSEDVKWPNGISVDDQWIYWTDAYLECIERITFSGQQRSVILDNL
PHPYAIAVFKNEIYWDDWSQLSIFRASKYSGSQMEILANQLTGLMDMKIFYKGKNTGSNA
CVPRPCSLLCLPKANNSRSCRCPEDVSSSVLPSGDLMCDCPQGYQLKNNTCVKQENTCLR
NQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTICDLDTQFRCQESGTCIPLSYKCDL
EDDCGDNSDESHCEMHQCRSDEYNCSSGMCIRSSWVCDGDNDCRDWSDEANCTAIYHTCE
ASNFQCRNGHCIPQRWACDGDTDCQDGSDEDPVNCEKKCNGFRCPNGTCIPSSKHCDGLR
DCSDGSDEQHCEPLCTHFMDFVCKNRQQCLFHSMVCDGIIQCRDGSDEDAAFAGCSQDPE
FHKVCDEFGFQCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFRCENGH
CIPNRWKCDRENDCGDWSDEKDCGDSHILPFSTPGPSTCLPNYYRCSSGTCVMDTWVCDG
YRDCADGSDEEACPLLANVTAASTPTQLGRCDRFEFECHQPKTCIPNWKRCDGHQDCQDG
RDEANCPTHSTLTCMSREFQCEDGEACIVLSERCDGFLDCSDESDEKACSDELTVYKVQN
LQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKTNTVLKVLKPD
TTYQVKVQVQCLSKAHNTNDFVTLRTPEGLPDAPRNLQLSLPREAEGVIVGHWAPPIHTH
GLIREYIVEYSRSGSKMWASQRAASNFTEIKNLLVNTLYTVRVAAVTSRGIGNWSDSKSI
TTIKGKVIPPPDIHIDSYGENYLSFTLTMESDIKVNGYVVNLFWAFDTHKQERRTLNFRG
SILSHKVGNLTAHTSYEISAWAKTDLGDSPLAFEHVMTRGVRPPAPSLKAKAINQTAVEC
TWTGPRNVVYGIFYATSFLDLYRNPKSLTTSLHNKTVIVSKDEQYLFLVRVVVPYQGPSS
DYVVVKMIPDSRLPPRHLHVVHTGKTSVVIKWESPYDSPDQDLLYAVAVKDLIRKTDRSY
KVKSRNSTVEYTLNKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDALKIITENDHVL
LFWKSLALKEKHFNESRGYEIHMFDSAMNITAYLGNTTDNFFKISNLKMGHNYTFTVQAR
CLFGNQICGEPAILLYDELGSGADASATQAARSTDVAAVVVPILFLILLSLGVGFAILYT
KHRRLQSSFTAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA
NT seq 6645 nt   +upstreamnt  +downstreamnt
atggcgacacggagcagcaggagggagtcgcgactcccgttcctattcaccctggtcgca
ctgctgccgcccggagctctctgcgaagtctggacgcagaggctgcacggcggcagcgcg
cccttgccccaggaccggggcttcctcgtggtgcagggcgacccgcgcgagctgcggctg
tgggcgcgcggggatgccaggggggcgagccgcgcggacgagaagccgctccggaggaaa
cggagcgctgccctgcagcccgagcccatcaaggtgtacggacaggttagtctgaatgat
tcccacaatcagatggtggtgcactgggctggagagaaaagcaacgtgatcgtggccttg
gcccgagatagcctggcattggcgaggcccaagagcagtgatgtgtacgtgtcttacgac
tatggaaaatcattcaagaaaatttcagacaagttaaactttggcttgggaaataggagt
gaagctgttatcgcccagttctaccacagccctgcggacaacaagcggtacatctttgca
gacgcttatgcccagtacctctggatcacgtttgacttctgcaacactcttcaaggcttt
tccatcccatttcgggcagctgatctcctcctacacagtaaggcctccaaccttctcttg
ggctttgacaggtcccaccccaacaagcagctgtggaagtcagatgactttggccagacc
tggatcatgattcaggaacatgtcaagtccttttcttggggaattgatccctatgacaaa
ccaaataccatctacattgaacgacatgaaccctctggctactccactgtcttccgaagt
acagatttcttccagtcccgggaaaaccaggaagtgatccttgaggaagtgagagatttt
cagcttcgggacaagtacatgtttgctacaaaggtggtgcatctcttgggcagtgaacag
cagtcttctgtccagctctgggtctcctttggccggaagcccatgagagcagcccagttt
gtcacaagacatcctattaatgaatattacatcgcagatgcctccgaggaccaggtgttt
gtgtgtgtcagccacagtaacaaccgcaccaatttatacatctcagaggcagaggggctg
aagttctccctgtccttggagaacgtgctctattacagcccaggaggggccggcagtgac
accttggtgaggtattttgcaaatgaaccatttgctgacttccaccgagtggaaggattg
caaggagtctacattgctactctgattaatggttctatgaatgaggagaacatgagatcg
gtcatcacctttgacaaagggggaacctgggagtttcttcaggctccagccttcacggga
tatggagagaaaatcaattgtgagctttcccagggctgttcccttcatctggctcagcgc
ctcagtcagctcctcaacctccagctccggagaatgcccatcctgtccaaggagtcggct
ccaggcctcatcatcgccactggctcagtgggaaagaacttggctagcaagacaaacgtg
tacatctctagcagtgctggagccaggtggcgagaggcacttcctggacctcactactac
acatggggagaccacggcggaatcatcacggccattgcccagggcatggaaaccaacgag
ctaaaatacagtaccaatgaaggggagacctggaaaacattcatcttctctgagaagcca
gtgtttgtgtatggcctcctcacagaacctggggagaagagcactgtcttcaccatcttt
ggctcgaacaaagagaatgtccacagctggctgatcctccaggtcaatgccacggatgcc
ttgggagttccctgcacagagaatgactacaagctgtggtcaccatctgatgagcggggg
aatgagtgtttgctgggacacaagactgttttcaaacggcggaccccccatgccacatgc
ttcaatggagaggactttgacaggccggtggtcgtgtccaactgctcctgcacccgggag
gactatgagtgtgacttcggtttcaagatgagtgaagatttgtcattagaggtttgtgtt
ccagatccggaattttctggaaagtcatactcccctcctgtgccttgccctgtgggttct
acttacaggagaacgagaggctaccggaagatttctggggacacttgtagcggaggagat
gttgaagcgcgactggaaggagagctggtcccctgtcccctggcagaagagaacgagttc
attctgtatgctgtgaggaaatccatctaccgctatgacctggcctcgggagccaccgag
cagttgcctctcaccgggctacgggcagcagtggccctggactttgactatgagcacaac
tgtttgtattggtccgacctggccttggacgtcatccagcgcctctgtttgaatggaagc
acagggcaagaggtgatcatcaattctggcctggagacagtagaagctttggcttttgaa
cccctcagccagctgctttactgggtagatgcaggcttcaaaaagattgaggtagctaat
ccagatggcgacttccgactcacaatcgtcaattcctctgtgcttgatcgtcccagggct
ctggtcctcgtgccccaagagggggtgatgttctggacagactggggagacctgaagcct
gggatttatcggagcaatatggatggttctgctgcctatcacctggtgtctgaggatgtg
aagtggcccaatggcatctctgtggacgaccagtggatttactggacggatgcctacctg
gagtgcatagagcggatcacgttcagtggccagcagcgctctgtcattctggacaacctc
ccgcacccctatgccattgctgtctttaagaatgaaatctactgggatgactggtcacag
ctcagcatattccgagcttccaaatacagtgggtcccagatggagattctggcaaaccag
ctcacggggctcatggacatgaagattttctacaaggggaagaacactggaagcaatgcc
tgtgtgcccaggccatgcagcctgctgtgcctgcccaaggccaacaacagtagaagctgc
aggtgtccagaggatgtgtccagcagtgtgcttccatcaggggacctgatgtgtgactgc
cctcagggctatcagctcaagaacaatacctgtgtcaaacaagagaacacctgtcttcgc
aaccagtatcgctgcagcaacgggaactgtatcaacagcatttggtggtgtgactttgac
aacgactgtggagacatgagcgatgagagaaactgccctaccaccatctgtgacctggac
acccagtttcgttgccaggagtctgggacttgtatcccactgtcctataaatgtgacctt
gaggatgactgtggagacaacagtgatgaaagtcattgtgaaatgcaccagtgccggagt
gacgagtacaactgcagttccggcatgtgcatccgctcctcctgggtatgtgacggggac
aacgactgcagggactggtctgatgaagccaactgtaccgccatctatcacacctgtgag
gcctccaacttccagtgccgaaacgggcactgcatcccccagcggtgggcgtgtgacggg
gatacggactgccaggatggttccgatgaggatccagtcaactgtgagaagaagtgcaat
ggattccgctgcccaaacggcacttgcatcccatccagcaaacattgtgatggtctgcgt
gattgctctgatggctccgatgaacagcactgcgagcccctctgtacgcacttcatggac
tttgtgtgtaagaaccgccagcagtgcctgttccactccatggtctgtgacggaatcatc
cagtgccgcgacgggtccgatgaggatgcggcgtttgcaggatgctcccaagatcctgag
ttccacaaggtatgtgatgagttcggtttccagtgtcagaatggagtgtgcatcagtttg
atttggaagtgcgacgggatggatgattgcggcgattattctgatgaagccaactgcgaa
aaccccacagaagccccaaactgctcccgctacttccagtttcggtgtgagaatggccac
tgcatccccaacagatggaaatgtgacagggagaacgactgtggggactggtctgatgag
aaggattgtggagattcacatattcttcccttctcgactcctgggccctccacgtgtctg
cccaattactaccgctgcagcagtgggacctgcgtgatggacacctgggtgtgcgacggg
taccgagattgtgcagatggctctgacgaggaagcctgccccttgcttgcaaacgtcact
gctgcctccactcccacccaacttgggcgatgtgaccgatttgagttcgaatgccaccaa
ccgaagacgtgtattcccaactggaagcgctgtgacggccaccaagattgccaggatggc
cgggacgaggccaattgccccacacacagcaccttgacttgcatgagcagggagttccag
tgcgaggacggggaggcctgcattgtgctctcggagcgctgcgacggcttcctggactgc
tcggacgagagcgatgaaaaggcctgcagtgatgagttgactgtgtacaaagtacagaat
cttcagtggacagctgacttctctggggatgtgactttgacctggatgaggcccaaaaaa
atgccctctgcttcttgtgtatataatgtctactacagggtggttggagagagcatatgg
aagactctggagacccacagcaataagacaaacactgtattaaaagtcttgaaaccagat
accacgtatcaggttaaagtacaggttcagtgtctcagcaaggcacacaacaccaatgac
tttgtgaccctgaggaccccagagggattgccagatgcccctcgaaatctccagctgtca
ctccccagggaagcagaaggtgtgattgtaggccactgggctcctcccatccacacccat
ggcctcatccgtgagtacattgtagaatacagcaggagtggttccaagatgtgggcctcc
cagagggctgctagtaactttacagaaatcaagaacttattggtcaacactctatacacc
gtcagagtggctgcggtgactagtcgtggaataggaaactggagcgattctaaatccatt
accaccataaaaggaaaagtgatcccaccaccagatatccacattgacagctatggtgaa
aattatctaagcttcaccctgaccatggagagtgatatcaaggtgaatggctatgtggtg
aaccttttctgggcatttgacacccacaagcaagagaggagaactttgaacttccgagga
agcatattgtcacacaaagttggcaatctgacagctcatacatcctatgagatttctgcc
tgggccaagactgacttgggggatagccctctggcatttgagcatgttatgaccagaggg
gttcgcccacctgcacctagcctcaaggccaaagccatcaaccagactgcagtggaatgt
acctggaccggcccccggaatgtggtttatggtattttctatgccacgtcctttcttgac
ctctatcgcaacccgaagagcttgactacttcactccacaacaagacggtcattgtcagt
aaggatgagcagtatttgtttctggtccgtgtagtggtaccctaccaggggccatcctct
gactacgttgtagtgaagatgatcccggacagcaggcttccaccccgtcacctgcatgtg
gttcatacgggcaaaacctccgtggtcatcaagtgggaatcaccgtatgactctcctgac
caggacttgttgtatgcagttgcagtcaaagatctcataagaaagactgacaggagctac
aaagtaaaatcccgtaacagcactgtggaatacacccttaacaagttggagcctggcggg
aaataccacatcattgtccaactggggaacatgagcaaagattccagcataaaaattacc
acagtttcattatcagcacctgatgccttaaaaatcataacagaaaatgatcatgttctt
ctgttttggaaaagcctggctttaaaggaaaagcattttaatgaaagcaggggctatgag
atacacatgtttgatagtgccatgaatatcacagcttaccttgggaatactactgacaat
ttctttaaaatttccaacctgaagatgggtcataattacacgttcaccgtccaagcaaga
tgcctttttggcaaccagatctgtggggagcctgccatcctgctgtacgatgagctgggg
tctggtgcagatgcatctgcaacgcaggctgccagatctacggatgttgctgctgtggtg
gtgcccatcttattcctgatactgctgagcctgggggtggggtttgccatcctgtacacg
aagcaccggaggctgcagagcagcttcaccgccttcgccaacagccactacagctccagg
ctggggtccgcaatcttctcctctggggatgacctgggggaagatgatgaagatgcccct
atgataactggattttcagatgacgtccccatggtgatagcctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (29)   
   RefGene (24)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
3D Structure (7)   
   PDB (7)   
Protein domain (10)   
   Pfam (10)   
All databases (89)   

Download RDF
DBGET integrated database retrieval system