KEGG   Homo sapiens (human): 7006
Entry
7006              CDS       T01001                                 
Symbol
TEC, PSCTK4
Name
(RefSeq) tec protein tyrosine kinase
  KO
K07364  tyrosine-protein kinase Tec [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04380  Osteoclast differentiation
hsa04660  T cell receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    7006 (TEC)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    7006 (TEC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    7006 (TEC)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     7006 (TEC)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  TEC family
   7006 (TEC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 PH SH3_1 BTK SH3_2 SH3_9 SH3_10 ABC1 PH_3 Kinase-like
Other DBs
NCBI-GeneID: 7006
NCBI-ProteinID: NP_003206
OMIM: 600583
HGNC: 11719
Ensembl: ENSG00000135605
UniProt: P42680
Structure
Position
4:complement(48135783..48269838)
AA seq 631 aa
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGRAEKKYRKGFIDVSKIK
CVEIVKNDDGVIPCQNKYPFQVVHDANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIKY
HPKFWTDGSYQCCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNS
EEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSN
NLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHY
HIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSY
EKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKL
THPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYL
ERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYS
RFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLR
CWQEKPEGRPSFEDLLRTIDELVECEETFGR
NT seq 1896 nt   +upstreamnt  +downstreamnt
atgaattttaacactattttggaggagattcttattaaaaggtcacagcagaaaaagaag
acatcgcccttaaactacaaagagagactttttgtacttacaaagtccatgctaacctac
tatgagggtcgagcagagaagaaatacagaaaggggtttattgatgtttcaaaaatcaag
tgtgtggaaatagtgaagaatgatgatggtgtcattccctgtcaaaataagtatccattt
caggttgttcatgatgctaacacactttacatttttgcacctagtccacaaagcagggac
ctgtgggtgaagaagttaaaagaagaaataaagaacaacaataatattatgattaaatat
catcctaaattctggacagatggaagttatcagtgttgtagacaaactgaaaaattagca
cccggatgtgaaaaatacaatctttttgagagcagtataagaaaagcactacctccagca
ccagaaacaaagaagcgaaggcctcccccaccaattccactagaagaagaagataatagt
gaagaaatcgttgtagccatgtatgatttccaagcagcagaaggacatgatctcagatta
gagagaggccaagagtatctcattttagaaaagaatgatgttcattggtggagagcaaga
gataaatatgggaatgaaggatatatcccaagtaattacgtaacgggaaagaaatcaaac
aacttagatcaatatgaatggtattgcagaaatatgaatagaagcaaggcagagcaactc
ctccgcagtgaagataaagaaggtggttttatggtaagggattccagtcaaccaggcttg
tacacagtctccctttataccaagtttggaggagaaggttcatcgggttttaggcattat
catataaaggaaacaacaacatctccaaagaagtattacctagctgaaaaacatgctttt
ggctccattcctgagattattgaatatcataagcacaatgcagcaggacttgtcaccagg
cttcggtacccagttagtgtgaaagggaagaatgcacccaccactgcaggattcagctat
gagaaatgggagattaacccttcagaactgacctttatgagggaattgggaagtggactg
tttggagtggtgaggcttggcaaatggcgagcccagtacaaagtcgcaatcaaagctatt
cgggaaggtgcaatgtgcgaggaggactttatagaagaagctaaagtgatgatgaaactg
acacacccgaagttagtgcagctttatggtgtgtgcacccagcagaaaccaatatacatt
gttactgagttcatggaaaggggctgccttctgaatttcctccgacagagacaaggtcat
ttcagtagagacgtactgctgagcatgtgtcaggatgtgtgtgaagggatggagtatctg
gagagaaacagcttcatccacagagatctggctgccagaaattgtctagtaagtgaggcg
ggagttgtaaaagtatctgattttggaatggccaggtatgttctggatgatcagtacaca
agttcttctggtgctaagtttcctgtgaagtggtgtccacctgaagtgtttaattacagc
cgcttcagcagcaaatcagatgtctggtcatttggtgttttaatgtgggaagtattcacg
gaaggcagaatgccttttgaaaaatacaccaattatgaagtggtaaccatggttactcga
ggccaccgactctaccagccgaagttggcgtccaactatgtgtatgaggtgatgctgaga
tgttggcaggagaaaccagagggaaggccttctttcgaagatctgctgcgcacaatagat
gaactagttgaatgtgaagaaacttttggaagataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (8)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (19)   
   RefSeq(nuc) (11)   
   GenBank (4)   
   EMBL (4)   
3D Structure (1)   
   PDB (1)   
Protein domain (12)   
   Pfam (12)   
All databases (54)   

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