KEGG   Homo sapiens (human): 7006
Entry
7006              CDS       T01001                                 

Symbol
TEC, PSCTK4
Name
(RefSeq) tec protein tyrosine kinase
  KO
K07364  tyrosine-protein kinase Tec [EC:2.7.10.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04380  Osteoclast differentiation
hsa04660  T cell receptor signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    7006 (TEC)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    7006 (TEC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    7006 (TEC)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     7006 (TEC)
Protein kinases [BR:hsa01001]
 Non-receptor tyrosine kinases
  TEC family
   7006 (TEC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 PH SH3_1 BTK SH3_9 SH3_2 SH3_10 ABC1 Kinase-like
Other DBs
NCBI-GeneID: 7006
NCBI-ProteinID: NP_003206
OMIM: 600583
HGNC: 11719
Ensembl: ENSG00000135605
Vega: OTTHUMG00000128623
Pharos: P42680(Tchem)
UniProt: P42680
Structure
PDB: 
2LUL

Position
4p12-p11
AA seq 631 aa
MNFNTILEEILIKRSQQKKKTSPLNYKERLFVLTKSMLTYYEGRAEKKYRKGFIDVSKIK
CVEIVKNDDGVIPCQNKYPFQVVHDANTLYIFAPSPQSRDLWVKKLKEEIKNNNNIMIKY
HPKFWTDGSYQCCRQTEKLAPGCEKYNLFESSIRKALPPAPETKKRRPPPPIPLEEEDNS
EEIVVAMYDFQAAEGHDLRLERGQEYLILEKNDVHWWRARDKYGNEGYIPSNYVTGKKSN
NLDQYEWYCRNMNRSKAEQLLRSEDKEGGFMVRDSSQPGLYTVSLYTKFGGEGSSGFRHY
HIKETTTSPKKYYLAEKHAFGSIPEIIEYHKHNAAGLVTRLRYPVSVKGKNAPTTAGFSY
EKWEINPSELTFMRELGSGLFGVVRLGKWRAQYKVAIKAIREGAMCEEDFIEEAKVMMKL
THPKLVQLYGVCTQQKPIYIVTEFMERGCLLNFLRQRQGHFSRDVLLSMCQDVCEGMEYL
ERNSFIHRDLAARNCLVSEAGVVKVSDFGMARYVLDDQYTSSSGAKFPVKWCPPEVFNYS
RFSSKSDVWSFGVLMWEVFTEGRMPFEKYTNYEVVTMVTRGHRLYQPKLASNYVYEVMLR
CWQEKPEGRPSFEDLLRTIDELVECEETFGR
NT seq 1896 nt   +upstreamnt  +downstreamnt
atgaattttaacactattttggaggagattcttattaaaaggtcacagcagaaaaagaag
acatcgcccttaaactacaaagagagactttttgtacttacaaagtccatgctaacctac
tatgagggtcgagcagagaagaaatacagaaaggggtttattgatgtttcaaaaatcaag
tgtgtggaaatagtgaagaatgatgatggtgtcattccctgtcaaaataagtatccattt
caggttgttcatgatgctaacacactttacatttttgcacctagtccacaaagcagggac
ctgtgggtgaagaagttaaaagaagaaataaagaacaacaataatattatgattaaatat
catcctaaattctggacagatggaagttatcagtgttgtagacaaactgaaaaattagca
cccggatgtgaaaaatacaatctttttgagagcagtataagaaaagcactacctccagca
ccagaaacaaagaagcgaaggcctcccccaccaattccactagaagaagaagataatagt
gaagaaatcgttgtagccatgtatgatttccaagcagcagaaggacatgatctcagatta
gagagaggccaagagtatctcattttagaaaagaatgatgttcattggtggagagcaaga
gataaatatgggaatgaaggatatatcccaagtaattacgtaacgggaaagaaatcaaac
aacttagatcaatatgaatggtattgcagaaatatgaatagaagcaaggcagagcaactc
ctccgcagtgaagataaagaaggtggttttatggtaagggattccagtcaaccaggcttg
tacacagtctccctttataccaagtttggaggagaaggttcatcgggttttaggcattat
catataaaggaaacaacaacatctccaaagaagtattacctagctgaaaaacatgctttt
ggctccattcctgagattattgaatatcataagcacaatgcagcaggacttgtcaccagg
cttcggtacccagttagtgtgaaagggaagaatgcacccaccactgcaggattcagctat
gagaaatgggagattaacccttcagaactgacctttatgagggaattgggaagtggactg
tttggagtggtgaggcttggcaaatggcgagcccagtacaaagtcgcaatcaaagctatt
cgggaaggtgcaatgtgcgaggaggactttatagaagaagctaaagtgatgatgaaactg
acacacccgaagttagtgcagctttatggtgtgtgcacccagcagaaaccaatatacatt
gttactgagttcatggaaaggggctgccttctgaatttcctccgacagagacaaggtcat
ttcagtagagacgtactgctgagcatgtgtcaggatgtgtgtgaagggatggagtatctg
gagagaaacagcttcatccacagagatctggctgccagaaattgtctagtaagtgaggcg
ggagttgtaaaagtatctgattttggaatggccaggtatgttctggatgatcagtacaca
agttcttctggtgctaagtttcctgtgaagtggtgtccacctgaagtgtttaattacagc
cgcttcagcagcaaatcagatgtctggtcatttggtgttttaatgtgggaagtattcacg
gaaggcagaatgccttttgaaaaatacaccaattatgaagtggtaaccatggttactcga
ggccaccgactctaccagccgaagttggcgtccaactatgtgtatgaggtgatgctgaga
tgttggcaggagaaaccagagggaaggccttctttcgaagatctgctgcgcacaatagat
gaactagttgaatgtgaagaaacttttggaagataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (5)   
DNA sequence (16)   
   RefSeq(nuc) (8)   
   GenBank (4)   
   EMBL (4)   
Protein domain (10)   
   Pfam (10)   
All databases (52)   

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