KEGG   Homo sapiens (human): 80349
Entry
80349             CDS       T01001                                 
Symbol
SKIC8, REC14, SKI8, WDR61
Name
(RefSeq) SKI8 subunit of superkiller complex
  KO
K12602  WD repeat-containing protein 61
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    80349 (SKIC8)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    80349 (SKIC8)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Ski complex
     80349 (SKIC8)
SSDB
Motif
Pfam: WD40_Prp19 WD40 WD40_WDHD1_1st Beta-prop_CAF1B_HIR1 WD40_MABP1-WDR62_2nd Beta-prop_EML_2 WD40_CDC20-Fz Beta-prop_WDR90_POC16_2nd WDR55 EIF3I Beta-prop_TEP1_2nd ANAPC4_WD40 WD40_MABP1-WDR62_1st Beta-prop_WDR75_1st Beta-prop_IFT122_1st Beta-prop_EML Beta-prop_SCAP Beta-prop_TEP1_C Beta-prop_RIG_2nd WDR90_beta-prop_4th Beta-prop_WDR19_1st eIF2A Beta-prop_Vps41 Beta-prop_DCAF4 Beta-prop_WDR35_TULP_N WD40_RFWD3 Beta-prop_NWD2_C Beta-prop_EIPR1 NBCH_WD40 Beta-prop_IFT140_1st Beta-prop_SPT8 Beta-prop_Nup120_160 Beta-prop_HPS5 Ge1_WD40 Cytochrom_D1 PROPPIN Beta-prop_WDR75_2nd Beta-prop_DCAF12 WD_LRWD1 Beta-prop_LRRK2 VPS8_N WDR54 Beta-prop_VPS8 Beta-prop_RIG_1st WD40_like GSDH Nucleoporin_N DUF2415 Beta-prop_IFT122_2nd Vgb_lyase
Other DBs
NCBI-GeneID: 80349
NCBI-ProteinID: NP_001290176
OMIM: 609540
HGNC: 30300
Ensembl: ENSG00000140395
UniProt: Q9GZS3
Structure
Position
15:complement(78283235..78299609)
AA seq 305 aa
MTNQYGILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVWKWRDERLDLQWSL
EGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPDSQY
LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG
KLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAF
CPDDTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI
YDCPI
NT seq 918 nt   +upstreamnt  +downstreamnt
atgaccaaccagtacggtattctcttcaaacaagagcaagcccatgatgatgccatttgg
tcagttgcttgggggacaaacaagaaggaaaactctgagacagtggtcacaggctcccta
gatgacctggtgaaggtctggaaatggcgtgatgagaggctggacctacagtggagtctg
gagggacatcagctgggagtggtgtctgtggacatcagccacaccctgcccattgctgca
tccagctctcttgatgctcatattcgtctttgggacttggaaaatggcaaacagataaag
tccatagatgcaggacctgtggatgcctggactttggccttttctcctgattcccagtat
ctggccacaggaactcatgtcgggaaagtgaacatttttggtgtggaaagtgggaaaaag
gaatattctttggacacgagaggaaaattcattcttagtattgcatatagtcctgatggg
aaatacctagccagtggagccatagatggaatcatcaatatttttgatattgcaactgga
aaacttctgcataccctggaaggccatgccatgcccattcgctccttgaccttttccccg
gactcccagctccttgtcactgcttcagatgatggctacatcaagatctatgatgtacaa
catgccaatttggctggcacgctgagcggccatgcctcctgggtgctgaacgttgcattc
tgtcctgatgacactcactttgtttccagttcgtctgacaaaagtgtaaaagtttgggat
gttggaacgaggacttgtgttcacaccttctttgatcaccaggatcaggtctggggagta
aaatacaatggaaatggttcaaaaattgtgtctgttggagatgaccaggaaattcacatc
tatgattgtccaatttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (15)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (35)   
   RefSeq(nuc) (7)   
   GenBank (14)   
   EMBL (14)   
3D Structure (22)   
   PDB (22)   
Protein domain (50)   
   Pfam (50)   
All databases (132)   

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