KEGG   Homo sapiens (human): 84706
Entry
84706             CDS       T01001                                 

Gene name
GPT2, ALT2, GPT_2, MRT49
Definition
(RefSeq) glutamic--pyruvic transaminase 2
  KO
K00814  alanine transaminase [EC:2.6.1.2]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00220  Arginine biosynthesis
hsa00250  Alanine, aspartate and glutamate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa01210  2-Oxocarboxylic acid metabolism
hsa01230  Biosynthesis of amino acids
Disease
H00768  Autosomal recessive mental retardation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    84706 (GPT2)
   00220 Arginine biosynthesis
    84706 (GPT2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01007 Amino acid related enzymes [BR:hsa01007]
    84706 (GPT2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.2  alanine transaminase
     84706 (GPT2)
Amino acid related enzymes [BR:hsa01007]
 Aminotransferase (transaminase)
  Class I
   84706 (GPT2)
SSDB
Motif
Pfam: Aminotran_1_2
Other DBs
NCBI-GeneID: 84706
NCBI-ProteinID: NP_597700
OMIM: 138210
HGNC: 18062
Ensembl: ENSG00000166123
Vega: OTTHUMG00000132541
Pharos: Q8TD30(Tbio)
UniProt: Q8TD30 A0A024R6R2
Structure
PDB: 
3IHJ

Position
16q11.2
AA seq 523 aa
MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAV
EYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPN
LLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDN
IYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENC
WALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADE
VYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLH
PEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLT
EDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVP
GSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA
NT seq 1572 nt   +upstreamnt  +downstreamnt
atgcagcgggcggcggcgctggtccggcggggctgtggtccccggacccccagctcctgg
ggccgcagccagagcagcgcggccgccgaggcctcggcggtgctcaaggtgcggcccgag
cgcagccggcgcgagcgcatcctcacgctggagtccatgaacccgcaggtgaaggcggtg
gagtacgccgtgcggggacccatcgtgctcaaggccggcgagatcgagctcgagctgcag
cggggtatcaaaaagccattcacagaggtcatccgagccaacatcggggacgcccaggct
atggggcagcagccaatcaccttcctccggcaggtgatggcactatgcacctacccaaac
ctgctggacagccccagcttcccagaagatgctaagaaacgtgcccggcggatcctgcag
gcttgtggcgggaacagcctggggtcctacagtgctagccagggtgtcaactgcatccgt
gaagatgtggctgcctacatcaccaggagggatggcggtgtgcctgcggaccccgacaac
atctacctgaccacgggagctagtgacggcatttctacgatcctgaagatcctcgtctcc
gggggcggcaagtcacggacaggtgtgatgatccccatcccacaatatcccctctattca
gctgtcatctctgagctcgacgccatccaggtgaattactacctggacgaggagaactgc
tgggcgctgaatgtgaatgagctccggcgggcggtgcaggaggccaaagaccactgtgat
cctaaggtgctctgcataatcaaccctgggaaccccacaggccaggtacaaagcagaaag
tgcatagaagatgtgatccactttgcctgggaagagaagctctttctcctggctgatgag
gtgtaccaggacaacgtgtactctccagattgcagattccactccttcaagaaggtgctg
tacgagatggggcccgagtactccagcaacgtggagctcgcctccttccactccacctcc
aagggctacatgggcgagtgtggttacagaggaggctacatggaggtgatcaacctgcac
cctgagatcaagggccagctggtgaagctgctgtcggtgcgcctgtgccccccagtgtct
gggcaggccgccatggacattgtcgtgaaccccccggtggcaggagaggagtcctttgag
caattcagccgagagaaggagtcggtcctgggtaatctggccaaaaaagcaaagctgacg
gaagacctgtttaaccaagtcccaggaattcactgcaaccccttgcagggggccatgtac
gccttccctcggatcttcattcctgccaaagctgtggaggctgctcaggcccatcaaatg
gctccagacatgttctactgcatgaagctcctggaggagactggcatctgtgtcgtgccc
ggcagtggctttgggcagagggaaggcacttaccacttcaggatgactatcctccctcca
gtggagaagctgaaaacggtgctgcagaaggtgaaagacttccacatcaacttcctggag
aagtacgcgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (25)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
Protein domain (1)   
   Pfam (1)   
All databases (75)   

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