KEGG   Homo sapiens (human): 85363
Entry
85363             CDS       T01001                                 
Symbol
TRIM5, RNF88, TRIM5alpha
Name
(RefSeq) tripartite motif containing 5
  KO
K10648  tripartite motif-containing protein 5 [EC:2.3.2.27]
Organism
hsa  Homo sapiens (human)
Pathway
hsa03250  Viral life cycle - HIV-1
hsa05170  Human immunodeficiency virus 1 infection
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    85363 (TRIM5)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    85363 (TRIM5)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    85363 (TRIM5)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     85363 (TRIM5)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRIM/RBCC proteins
    85363 (TRIM5)
SSDB
Motif
Pfam: SPRY zf-RING_UBOX zf-C3HC4_4 zf-C3HC4 zf-B_box zf-C3HC4_2 RING_XB3-XBAT31 zf-RING_5 zf-RING_2 TMF_TATA_bd zf-C3HC4_3 FAM76 U-box zf-RING_4 Mis12 zf-RING_10 zf-Nse Baculo_IE-1
Other DBs
NCBI-GeneID: 85363
NCBI-ProteinID: NP_149023
OMIM: 608487
HGNC: 16276
Ensembl: ENSG00000132256
UniProt: Q9C035
Structure
Position
11:complement(5588635..5685074)
AA seq 493 aa
MASGILVNVKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRI
SYQPENIRPNRHVANIVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERS
QEHRGHHTFLTEEVAREYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTN
VLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQ
GSVMELLQGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDVRRYWVD
VTVAPNNISCAVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHY
WEVDVSKKTAWILGVCAGFQPDAMCNIEKNENYQPKYGYWVIGLEEGVKCSAFQDSSFHT
PSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPYLNPR
KCGVPMTLCSPSS
NT seq 1482 nt   +upstreamnt  +downstreamnt
atggcttctggaatcctggttaatgtaaaggaggaggtgacctgccccatctgcctggaa
ctcctgacacaacccctgagcctggactgcggccacagcttctgccaagcatgcctcact
gcaaaccacaagaagtccatgctagacaaaggagagagtagctgccctgtgtgccggatc
agttaccagcctgagaacatacggcctaatcggcatgtagccaacatagtggagaagctc
agggaggtcaagttgagcccagaggggcagaaagttgatcattgtgcacgccatggagag
aaacttctactcttctgtcaggaggacgggaaggtcatttgctggctttgtgagcggtct
caggagcaccgtggtcaccacacgttcctcacagaggaggttgcccgggagtaccaagtg
aagctccaggcagctctggagatgctgaggcagaagcagcaggaagctgaagagttagaa
gctgacatcagagaagagaaagcttcctggaagactcaaatacagtatgacaaaaccaac
gtcttggcagattttgagcaactgagagacatcctggactgggaggagagcaatgagctg
caaaacctggagaaggaggaggaagacattctgaaaagccttacgaactctgaaactgag
atggtgcagcagacccagtccctgagagagctcatctcagatctggagcatcggctgcag
gggtcagtgatggagctgcttcagggtgtggatggcgtcataaaaaggacggagaacgtg
accttgaagaagccagaaacttttccaaaaaatcaaaggagagtgtttcgagctcctgat
ctgaaaggaatgctagaagtgtttagagagctgacagatgtccgacgctactgggttgat
gtgacagtggctccaaacaacatttcatgtgctgtcatttctgaagataagagacaagtg
agctctccgaaaccacagataatatatggggcacgagggacaagataccagacatttgtg
aatttcaattattgtactggcatcctgggctctcaaagtatcacatcagggaaacattac
tgggaggtagacgtgtccaagaaaactgcttggatcctgggggtatgtgctggcttccaa
cctgatgcaatgtgtaatattgaaaaaaatgaaaattatcaacctaaatacggctactgg
gttatagggttagaggaaggagttaaatgtagtgctttccaggatagttccttccatact
ccttctgttcctttcattgtgcccctctctgtgattatttgtcctgatcgtgttggagtt
ttcctagactatgaggcttgcactgtctcattcttcaatatcacaaaccatggatttctc
atctataagttttctcactgttctttttctcagcctgtatttccatatttaaatcctaga
aaatgtggagtccccatgactctgtgctcaccaagctcttga

  All links  
Disease (1)   
   OMIM (1)   
Gene (22)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (70)   
   RefSeq(nuc) (34)   
   GenBank (18)   
   EMBL (18)   
3D Structure (2)   
   PDB (2)   
Protein domain (18)   
   Pfam (18)   
All databases (136)   

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