KEGG   Homo sapiens (human): 9615
Entry
9615              CDS       T01001                                 
Symbol
GDA, CYPIN, GAH, GUANASE, NEDASIN
Name
(RefSeq) guanine deaminase
  KO
K01487  guanine deaminase [EC:3.5.4.3]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
hsa01232  Nucleotide metabolism
Module
hsa_M00959  Guanine ribonucleotide degradation, GMP => Urate
Network
nt06027  Purine salvage pathway
  Element
N01424  HPRT1 deficiency in guanine metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    9615 (GDA)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.3  guanine deaminase
     9615 (GDA)
SSDB
Motif
Pfam: Amidohydro_1 Amidohydro_3
Other DBs
NCBI-GeneID: 9615
NCBI-ProteinID: NP_004284
OMIM: 139260
HGNC: 4212
Ensembl: ENSG00000119125
UniProt: Q9Y2T3
Structure
Position
9:72114608..72259869
AA seq 454 aa
MCAAQMPPLAHIFRGTFVHSTWTCPMEVLRDHLLGVSDSGKIVFLEEASQQEKLAKEWCF
KPCEIRELSHHEFFMPGLVDTHIHASQYSFAGSSIDLPLLEWLTKYTFPAEHRFQNIDFA
EEVYTRVVRRTLKNGTTTACYFATIHTDSSLLLADITDKFGQRAFVGKVCMDLNDTFPEY
KETTEESIKETERFVSEMLQKNYSRVKPIVTPRFSLSCSETLMGELGNIAKTRDLHIQSH
ISENRDEVEAVKNLYPSYKNYTSVYDKNNLLTNKTVMAHGCYLSAEELNVFHERGASIAH
CPNSNLSLSSGFLNVLEVLKHEVKIGLGTDVAGGYSYSMLDAIRRAVMVSNILLINKVNE
KSLTLKEVFRLATLGGSQALGLDGEIGNFEVGKEFDAILINPKASDSPIDLFYGDFFGDI
SEAVIQKFLYLGDDRNIEEVYVGGKQVVPFSSSV
NT seq 1365 nt   +upstreamnt  +downstreamnt
atgtgtgccgctcagatgccgcccctggcgcacatcttccgagggacgttcgtccactcc
acctggacctgccccatggaggtgctgcgggatcacctcctcggcgtgagcgacagcggc
aaaatagtgtttttagaagaagcatctcaacaggaaaaactggccaaagaatggtgcttc
aagccgtgtgaaataagagaactgagccaccatgagttcttcatgcctgggctggttgat
acacacatccatgcctctcagtattcctttgctggaagtagcatagacctgccactcttg
gagtggctgaccaagtacacatttcctgcagaacacagattccagaacatcgactttgca
gaagaagtatataccagagttgtcaggagaacactaaagaatggaacaaccacagcttgt
tactttgcaacaattcacactgactcatctctgctccttgccgacattacagataaattt
ggacagcgggcatttgtgggcaaagtttgcatggatttgaatgacacttttccagaatac
aaggagaccactgaggaatcgatcaaggaaactgagagatttgtgtcagaaatgctccaa
aagaactattctagagtgaagcccatagtgacaccacgtttttccctctcctgctctgag
actttgatgggtgaactgggcaacattgctaaaacccgtgatttgcacattcagagccat
ataagtgaaaatcgtgatgaagttgaagctgtgaaaaacttataccccagttataaaaac
tacacatctgtgtatgataaaaacaatcttttgacaaataagacagtgatggcacacggc
tgctacctctctgcagaagaactgaacgtattccatgaacgaggagcatccatcgcacac
tgtcccaattctaatttatcgctcagcagtggatttctaaatgtgctagaagtcctgaaa
catgaagtcaagatagggctgggtacagacgtggctggtggctattcatattccatgctt
gatgcaatcagaagagcagtgatggtttccaatatccttttaattaataaggtaaatgag
aaaagcctcaccctcaaagaagtcttcagactagctactcttggaggaagccaagccctg
gggctggatggtgagattggaaactttgaagtgggcaaggaatttgatgccatcctgatc
aaccccaaagcatccgactctcccattgacctgttttatggggacttttttggtgatatt
tctgaggctgttatccagaagttcctctatctaggagatgatcgaaatattgaagaggtt
tatgtgggcggaaagcaggtggttccgttttccagctcagtgtaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (17)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (55)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (53)   
DNA sequence (104)   
   RefSeq(nuc) (68)   
   GenBank (18)   
   EMBL (18)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (182)   

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