KEGG   Homo sapiens (human): 9855
Entry
9855              CDS       T01001                                 
Symbol
FARP2, FIR, FRG, PLEKHC3
Name
(RefSeq) FERM, ARH/RhoGEF and pleckstrin domain protein 2
  KO
K06082  FERM, RhoGEF and pleckstrin domain protein 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04015  Rap1 signaling pathway
hsa04520  Adherens junction
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    9855 (FARP2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    9855 (FARP2)
SSDB
Motif
Pfam: RhoGEF FERM_C PH FERM_N FERM_M FA SOS1_NGEF_PH PH_13 RHG20_PH IQ_SEC7_PH PH_11
Other DBs
NCBI-GeneID: 9855
NCBI-ProteinID: NP_055623
OMIM: 617586
HGNC: 16460
Ensembl: ENSG00000006607
UniProt: O94887
Position
2:241356285..241494841
AA seq 1054 aa
MGEIEGTYRVLQTAGMRLGAQTPVGVSTLEPGQTLLPRMQEKHLHLRVKLLDNTMEIFDI
EPKCDGQVLLTQVWKRLNLVECDYFGMEFQNTQSYWIWLEPMKPIIRQIRRPKNVVLRLA
VKFFPPDPGQLQEEYTRYLFALQLKRDLLEERLTCADTTAALLTSHLLQSEIGDYDETLD
REHLKVNEYLPGQQHCLEKILEFHQKHVGQTPAESDFQVLEIARKLEMYGIRFHMASDRE
GTKIQLAVSHMGVLVFQGTTKINTFNWSKVRKLSFKRKRFLIKLHPEVHGPYQDTLEFLL
GSRDECKNFWKICVEYHTFFRLLDQPKPKAKAVFFSRGSSFRYSGRTQKQLVDYFKDSGM
KRIPYERRHSKTHTSVRALTADLPKQSISFPEGLRTPASPSSANAFYSLSPSTLVPSGLP
EFKDSSSSLTDPQVSYVKSPAAERRSGAVAGGPDTPSAQPLGPPALQPGPGLSTKSPQPS
PSSRKSPLSLSPAFQVPLGPAEQGSSPLLSPVLSDAGGAGMDCEEPRHKRVPADEAYFIV
KEILATERTYLKDLEVITVWFRSAVVKEDAMPATLMTLLFSNIDPIYEFHRGFLREVEQR
LALWEGPSKAHTKGSHQRIGDILLRNMRQLKEFTSYFQRHDEVLTELEKATKRCKKLEAV
YKEFELQKVCYLPLNTFLLKPIQRLLHYRLLLRRLCGHYSPGHHDYADCHDALKAITEVT
TTLQHILIRLENLQKLTELQRDLVGIENLIAPGREFIREGCLHKLTKKGLQQRMFFLFSD
MLLYTSKGVAGTSHFRIRGLLPLQGMLVEESDNEWSVPHCFTIYAAQKTIVVAASTRLEK
EKWMLDLNSAIQAAKSGGDTAPALPGRTVCTRPPRSPNEVSLEQESEDDARGVRSSLEGH
GQHRANTTMHVCWYRNTSVSRADHSAAVENQLSGYLLRKFKNSHGWQKLWVVFTNFCLFF
YKTHQDDYPLASLPLLGYSVSIPREADGIHKDYVFKLQFKSHVYFFRAESKYTFERWMEV
IQGASSSAGRAPSIVQDGPQPSSGLEGMVRGKEE
NT seq 3165 nt   +upstreamnt  +downstreamnt
atgggggagatagaaggaacatacagagtcctgcagactgcagggatgcgcttgggtgcc
cagacccctgtgggagttagcacccttgagcctgggcagactctcttgcccagaatgcaa
gagaagcacctgcacctcagagtaaagctgctggacaacaccatggaaatatttgacatt
gagcctaaatgcgatggccaggtattactgacacaagtgtggaagcgtttaaacctggta
gaatgtgactacttcgggatggagtttcaaaatactcagtcctactggatttggcttgaa
cctatgaaacccatcattaggcaaatacgaaggccaaagaatgtggtgcttcgcctagct
gtaaaattttttccacctgatcctggtcagctacaagaagaatatacaagatacttgttt
gccttgcaacttaagagagacctgctggaagagcgtttgacctgtgctgacaccacagcg
gcccttctcacgtcccatctcctgcagtcggaaataggagattacgatgaaacgctggac
cgagagcacctcaaagtgaacgagtatttgcctggccagcagcactgccttgagaagata
ctagaattccatcagaagcacgtgggccagacacctgctgagtcggatttccaggtgctc
gaaattgctcgaaagttggaaatgtacggcatcagatttcacatggcttctgacagggaa
ggaaccaagattcaactggcagtttcccacatgggtgtactcgtgttccagggcaccacc
aaaatcaacactttcaactggtccaaggtccgtaaactaagcttcaagaggaaaagattt
cttatcaaacttcatccagaggttcatggaccttaccaggacacattagaatttttgttg
ggtagtagagatgaatgtaagaacttctggaagatttgtgtggagtatcacacctttttt
agacttttggaccaacctaagccaaaagcaaaagccgtcttcttcagccggggctcctcc
ttcagatacagtggaagaactcagaaacaactagtagattatttcaaagacagtggaatg
aagagaattccatatgaaagaaggcacagcaagacccacacgtccgttcgagctctgact
gcagacctaccaaaacagagcatctcattccccgagggattgaggactcctgcctcccca
tcttcagcgaatgccttttactcgctctctccctccactctggtcccctctggcctgcca
gagtttaaggacagcagcagctccctcacagatccccaggtttcctacgtcaagagtcca
gctgcagagaggcgcagtggagcagtggctggaggccccgacacaccatcggcccagccc
ctcgggccccccgcactccagcctggtccaggcctttccacgaagagtcctcagccttct
ccctccagccggaagagccccctgagtctgagccctgcatttcaggtgcctttgggccca
gctgaacagggctcatccccactcctgagccctgtcctcagtgatgctggcggagccggg
atggactgcgaggagcccagacacaagcgcgtgcctgcagacgaggcctacttcatagtc
aaagagattctcgctacagaacgaacatacctcaaggatttagaagttattaccgtgtgg
ttccgcagcgcagtggtgaaggaggacgccatgcctgcgactctgatgacgctgctcttc
tccaacatcgatcccatctatgagttccacagaggcttcctgcgcgaggtggagcagagg
ctggcactctgggaagggccctccaaagcccacacaaaaggcagtcatcaacgaatcggg
gacatcctgctcaggaacatgcgccagttaaaggagtttaccagctacttccaaagacat
gacgaggtcctaacagaactggaaaaggctaccaaacgctgtaagaagttggaggcagtg
tacaaggagtttgagctgcagaaggtctgctacttgcctctcaacacgttcctgctgaag
cccatccagcggctgctgcactaccgcctgctgctgcgccgcctatgcggacattacagc
cccgggcaccatgactacgctgactgccatgacgccctgaaagccatcacagaggtgacc
accacactacagcacattctcatccggctggagaacctgcagaagctaacggagctgcag
cgggacctggtgggcatagagaacctcattgctcctggcagggagttcatccgtgagggc
tgccttcacaagctcaccaagaagggcctgcagcagaggatgttttttctgttctcagat
atgttgctgtacacaagcaaaggagttgcagggaccagccacttccggatccggggcctc
cttcccctccaaggcatgctggtggaagaaagtgataacgagtggtctgttccacactgt
ttcaccatctacgcggctcagaaaacaatcgtggtggcagccagcactcggctggagaaa
gagaagtggatgctggacctgaactccgcgatccaagcagccaagagtggcggtgacacg
gcccctgcactgccaggccgcactgtgtgcactcgtccccccagatcccccaacgaggta
tctctggagcaggagtcagaagatgatgctcggggtgtccgcagctccctggaggggcat
ggccagcaccgggccaacaccacaatgcacgtgtgctggtaccggaacaccagcgtgtcc
agggcagaccacagtgcagctgtcgagaaccagctttcaggatatctgctaagaaagttc
aaaaacagtcatggctggcagaagctctgggtcgtctttaccaacttctgtttgttcttc
tacaaaactcatcaggatgactacccactggccagcctcccgctgctgggctacagcgtg
agcatccccagggaggccgatggcatacacaaagactatgttttcaagctccagttcaaa
tcccacgtctacttcttccgggctgagagcaagtacacatttgaaaggtggatggaggtg
atccagggggccagcagctcagccgggagggccccaagcatcgtgcaggatggcccccaa
ccctcctcagggctggaggggatggtcagggggaaggaggaatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (23)   
   RefGene (16)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (41)   
   RefSeq(nuc) (21)   
   GenBank (10)   
   EMBL (10)   
Protein domain (11)   
   Pfam (11)   
All databases (99)   

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