KEGG   Kryptolebias marmoratus (mangrove rivulus): 108243522
Entry
108243522         CDS       T05608                                 
Symbol
arhgef12a
Name
(RefSeq) rho guanine nucleotide exchange factor 12 isoform X1
  KO
K07532  Rho guanine nucleotide exchange factor 12
Organism
kmr  Kryptolebias marmoratus (mangrove rivulus)
Pathway
kmr04270  Vascular smooth muscle contraction
kmr04625  C-type lectin receptor signaling pathway
kmr04810  Regulation of actin cytoskeleton
Brite
KEGG Orthology (KO) [BR:kmr00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    108243522 (arhgef12a)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    108243522 (arhgef12a)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    108243522 (arhgef12a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:kmr04131]
    108243522 (arhgef12a)
Membrane trafficking [BR:kmr04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    108243522 (arhgef12a)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 PDZ_2
Other DBs
NCBI-GeneID: 108243522
NCBI-ProteinID: XP_017284495
Position
LG2:13435978..13478349
AA seq 1448 aa
MSDTQSSFTDRFNKKAIRTSSILSKDHPPDKKPKSDKTSPPSNEFDPTEALVVQKSGSSS
VLAEGKPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKEDGAAMRAGVQTGDRIIK
VNGTLVTHSNHTEVVKLIKSGSYVALTVLGRPPGLPQIPLPEADPETLGISLSSPNSPAS
ERPYSPLNCLSSSLQQWDENGSACNQRADISLKKFSKEQQELQAMKEEYNRNPSPKLLKD
IQEATKHIPQLQGQLFKATGTTQEAVSGGDEDNSSIIETDCVAAPKGENSTDLSWSSTPA
SRMFGPGSPDSQCPKDSSCASPHSTPRNSFNSYHSPEAEDTTDLEPLSPIPVGSPPPSRP
GFQIIGAEDDYFDSDQEQTNGQFNSFNSIEQLKSRPAHLAAFLHHVISQFDPAPVLCYLY
ADLYKQTNSKETRRVFLDFHAFFMDRAANLKVPVPESVSSDLNRRRMELIPEEINRQHVQ
TLQDSLFPDIQKHLEDFRQKRSMGLTVAEVELTRLDQERVRDRVTLERERSYAENILSKI
DDILITTQPTEEEKCTTIQDVIYTYMKHLGVRVKEPRNLEPKRVRISFLPKMKKSMKTDK
EGDEKVEKKPRFNFLAPQRRPSRIESASAGKTQDNRPRPQKQISQPTLGTNEQMETGLRG
SQSSEGSELTHSLSVSTSSSNSIIHSFDTSRDADIGGTPTSGPSKLLNDSIQSDPLGGLS
CPASHLEFYGLDHLQEDDRESDRAHEGTPKAIRRFEGLGAADVQSEDDQGTDSEHDPPNW
QQLVGREVLAGLRPHEIKRQEVINELFYTERAHVRMLKVLDHIFYQKLSKDAILPPADIK
NIFTNLEEVLQLHVSILEQMTAVRKRNESSVIDQIGDDLLSWFSGGEEEKIKRAVGTFCS
NQPFALEIIKTKQKKDSRFTSFIQEAESNRLCRRLQLKDIIPVEMLRLTKYPLLLDNIVK
YTDNAKEKAKVKQAADCCRRILSHVNQALKESEDKQKLEDYQRRLDLSSLKQTDNPMILE
LKNLDLTKKTLIHKGPLSWKVNKDKIIELFTLLLEDVLVLLQKQDERLILKCHSKNLAGA
PDTKHIYSPIIKLSTVLVRSVATDNKAFFVLSMSENGPQIYELMAPTVSDQKTWQSLISK
RADAIKAKPHSVIPLPQTDRERDGVEIISAGASRLSRDPDRTSTGSTQSTDKESSSASRS
ALQSSPIGSNPFEEVKKDDEEEEEGEEEDGDGFVDPELSYQVAEVDREGDLFDVFPSRAE
EALKTLAALKQVLVTQLMSQEAAEQNKRSTGARLLRTTSLRTPTDSRATVMVHNSSEKSS
SKTQDLTQDLGSGDTGFFDSPEDYGCLVLEGYGGTGESSTDDDILASTTGKPLSTSQVCA
ADSGINLRFSSTSQAGSLSTFSRQVLSHLRNLQTNLNYLKEVEAKYNNLISQRPERSITD
TDENKDKR
NT seq 4347 nt   +upstreamnt  +downstreamnt
atgagtgacacacagtccagcttcactgacaggtttaacaagaaagcaatcagaaccagc
agcattctcagtaaagaccatccgcctgacaagaaacccaaaagtgataaaacctcacct
ccctccaatgaatttgacccgacagaagctctggtggtgcagaagagtggcagcagcagt
gtgctagcagaggggaagcctgagtcctgtggtctggtccagcgatgtgtaatcatccag
aaagatgaaaacggcttcgggctcacggtcagcggtgacaacccagtgtttgtgcagctg
gtcaaagaagatggggctgcgatgcgggcaggtgttcagacaggagacaggatcattaag
gttaacgggacccttgttacacattctaatcacactgaagttgtgaaacttatcaaatcg
ggctcttatgtggccctcacggttttgggacgccctccaggacttccccagatccctttg
cctgaagcagatcccgagactttgggtattagcctttcctctcccaactctccagcgtca
gaacgcccatacagtcctctgaactgcctttcctcctcactgcaacaatgggatgaaaac
ggcagcgcctgcaaccagagggctgacatctcgctgaagaagttctcaaaagaacagcag
gagctgcaggccatgaaagaggagtacaacaggaacccctcccccaaactactgaaagac
attcaggaagcaacaaaacacattcctcagctgcagggtcagctcttcaaggccactggg
acgacacaggaggctgtttcaggtggggatgaagacaatagtagcataatagagacagat
tgcgtagctgcccctaaaggagaaaacagcacagacctgtcctggagcagcactcctgcg
tctcgcatgtttggacccggttctccagatagccagtgtccaaaagactcctcctgtgca
agcccacacagcacccccaggaacagcttcaactcctaccactccccagaggcagaggat
accaccgacctggagcctctgtctcccatcccagttggcagtcccccgccttctcgcccc
ggctttcaaataataggagctgaagacgactactttgattcagaccaagagcaaacaaac
ggccagtttaacagctttaacagtattgagcagctcaagtctcgtcctgcccacctcgca
gcattcctgcaccatgtcatctcccagttcgaccccgctccagtgctgtgctacctctat
gctgacctctataagcaaactaactccaaagagaccagacgggtgtttttggacttccac
gccttctttatggaccgagcagcaaatttaaaagttcctgttcctgaatcagtttcttct
gatctcaaccgacggcggatggagctgatcccagaggaaataaacagacagcatgttcaa
acactgcaggactctctgttccctgacattcagaaacacctcgaggacttcaggcaaaaa
cgcagcatgggcctgacggtggctgaagttgagctgaccagactggatcaagagagagtc
agagaccgggtcactcttgagcgggaacgctcgtacgccgaaaacatcctcagcaaaata
gatgacatcctgataactactcaacctacagaggaagaaaaatgcactacaatacaggat
gttatctatacgtacatgaagcaccttggtgtgagggtcaaggaacctcgaaatctggaa
cccaaacgtgttcggatcagctttcttcctaagatgaagaaaagcatgaagacagataag
gagggagatgagaaagtagagaaaaaacccagatttaattttcttgcacctcagcgtcgg
cccagccgcattgaatcagcatcagcgggtaaaacccaggacaatcgccccaggccacag
aaacagatctctcagcccacactggggacaaacgaacaaatggaaactggtctaagaggc
agccaatccagcgaaggctcggaactcacccactccctgtccgtcagcacctcgtcttca
aacagcatcatccacagcttcgacacaagccgagatgctgatatcggtgggacaccaaca
tcaggcccctccaagctgctgaatgacagcattcagtctgaccctctaggtgggttgtca
tgtcctgcttcgcacttggagttttatggtctggaccatcttcaggaggatgacagagaa
agtgacagagctcacgagggaacaccaaaggccatcagaagatttgagggactgggtgct
gctgatgttcagagtgaggacgatcagggtaccgactctgagcacgatccgccgaactgg
cagcagttggtggggcgagaagtcctggcaggtctcaggcctcacgagatcaagagacaa
gaagttatcaatgagctgttttacacggagcgtgcgcatgtacgcatgctcaaggttttg
gaccacattttctaccagaagctttccaaagatgccatccttcctcctgctgacatcaag
aacatcttcaccaacctggaggaggtcttacagctgcacgtttcaattcttgagcaaatg
acggccgttcgtaagagaaacgagtcgtcagtaattgatcaaataggagacgacttgctc
tcctggttcagcggcggggaggaggagaagatcaagcgagcagtggggacgttttgcagc
aaccagccttttgctctggagatcatcaagaccaagcagaagaaagactccaggtttacg
tcattcattcaggaggcagagagtaacaggctgtgtcgccgactgcagcttaaagacatc
attcctgtagagatgctgcggctcaccaaatatccgttgctgctggacaacattgtcaag
tacacagataacgccaaggagaaggctaaagtaaagcaggcggcagactgctgtagaagg
atcctcagtcatgttaaccaggctttgaaagagtccgaggacaagcagaaattagaagac
tatcagagaagattggacctctcctcactgaagcagacagataaccccatgatcctggag
ctaaagaacctggatctaaccaagaagacgttgattcacaagggtccgctgtcatggaaa
gtgaacaaagacaagattattgagctgttcacgctcctcttggaggacgttctcgttctg
ctacagaaacaagatgaacgtctaatccttaagtgccacagcaaaaacctggcaggcgcc
ccagacaccaagcatatctacagccccatcatcaagctcagcactgttctagtgcgttct
gtggctacagacaacaaggccttctttgtgctctccatgtcagaaaacggtccccagatc
tacgagctcatggcgcccacagtctcagatcagaaaacgtggcaaagtctgatctccaag
agagctgatgcaataaaagccaaacctcacagcgtcataccattacctcagactgacagg
gagagagatggagtggagatcatatcagcaggtgcttccagactgagtagagacccggac
cgcacgtccaccggcagcactcagtccacagataaagagagcagctcagcttctagaagt
gcattgcagagttcgccgattggtagtaatccatttgaagaggtgaagaaagatgacgag
gaggaggaggagggggaggaggaggacggggatggctttgtggacccagagctttcttat
caagtggctgaagtcgacagagaaggagacttgtttgatgtgtttccctcgagagcagag
gaagcactaaaaacactggcagcattgaagcaggttttagtgacccagctgatgtcccag
gaggccgcagagcaaaacaaacgctccactggagcccgtctcctcaggaccacctctctg
cggaccccaacagacagccgcgcaacggtgatggtccacaacagctcggagaaaagcagt
tcaaaaacacaggacctgacccaggatctgggatcgggagacactggattctttgactca
cctgaggactacggatgcttagtcctggagggctacggtggcaccggggagagcagcaca
gatgatgacatcttggcatcaaccactgggaagccgctgagcacctcacaagtctgtgct
gccgactctggcatcaatttgcggttttcctcaacgtcacaggccggcagcctctccact
ttcagcagacaggtgctgtctcaccttcgaaatcttcagaccaacctcaactacctgaag
gaggttgaggctaagtacaataatttaataagccaaaggccagagaggtcaataacagac
acggatgaaaacaaagataagagatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (6)   
   Pfam (6)   
All databases (22)   

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