KEGG ORTHOLOGY: K05061

ORTHOLOGY: K05061

Entry

K05061                      KO

Symbol

CSF3R, CD114

Name

granulocyte colony-stimulating factor receptor

Pathway

map04060

Cytokine-cytokine receptor interaction

map04151

PI3K-Akt signaling pathway

map04630

JAK-STAT signaling pathway

map04640

Hematopoietic cell lineage

map05200

Pathways in cancer

Disease

H00100

Neutropenic disorders

H02410

Myelodysplastic/myeloproliferative neoplasms

H02412

Atypical chronic myeloid leukemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
   04151 PI3K-Akt signaling pathway
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
   04090 CD molecules
    K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
Cytokine receptors [BR:ko04050]
Interleukin receptor families
  Prolactin receptor family
   K05061  CSF3R, CD114; granulocyte colony-stimulating factor receptor
CD molecules [BR:ko04090]
Proteins
  K05061  CD114, CSF3R; colony stimulating factor 3 receptor (granulocyte)

Genes

HSA:	1441(CSF3R)

PTR:	456756(CSF3R)

PPS:	100974292(CSF3R)

GGO:	101128750(CSF3R)

PON:	100433338(CSF3R)

NLE:	100594510(CSF3R)

HMH:	116472954(CSF3R)

MCC:	713485(CSF3R)

MCF:	102132219(CSF3R)

MTHB:

126959228

MNI:	105494725(CSF3R)

CSAB:

103225104(CSF3R)

CATY:

105594754(CSF3R)

PANU:

101012178(CSF3R)

TGE:	112625944(CSF3R)

MLEU:

105545944(CSF3R)

RRO:	104660161(CSF3R)

RBB:	108537272(CSF3R)

TFN:	117087217 117092868(CSF3R)

PTEH:

111555820(CSF3R)

CANG:

105521209(CSF3R)

CJC:	100393434(CSF3R)

SBQ:	101042318(CSF3R)

CIMI:

108290072(CSF3R)

CSYR:

103254218 103262364(CSF3R)

MMUR:

105871730(CSF3R)

LCAT:

123635757(CSF3R)

PCOQ:

105808649(CSF3R)

OGA:	100966247(CSF3R)

MMU:	12986(Csf3r)

MCAL:

110293219(Csf3r)

MPAH:

110323626(Csf3r)

RNO:	298518(Csf3r)

MCOC:

116096625(Csf3r)

ANU:	117709275(Csf3r)

MUN:	110540287(Csf3r)

CGE:	100760185(Csf3r)

MAUA:

106022359(Csf3r)

PROB:

127225324(Csf3r)

PLEU:

114704288(Csf3r)

MORG:

121448628(Csf3r)

MFOT:

126507300

AAMP:

119816863(Csf3r)

NGI:	103733325(Csf3r)

HGL:	101723599(Csf3r)

CPOC:

100717194(Csf3r)

CCAN:

109690426(Csf3r)

DORD:

105999115(Csf3r)

DSP:	122111398(Csf3r)

PLOP:

125354924(Csf3r)

NCAR:

124990733

MMMA:

107141944(Csf3r)

OCU:

100342746

OPI:	101517668(CSF3R)

TUP:	102471059(CSF3R)

GVR:	103606067 103606070(CSF3R)

CFA:	607605(CSF3R)

CLUD:

112642387(CSF3R)

VVP:	112914671(CSF3R)

VLG:	121481638(CSF3R)

NPO:	129520704(CSF3R)

AML:	100464681(CSF3R)

UMR:	103666378(CSF3R)

UAH:	113268281(CSF3R)

UAR:	123782335(CSF3R)

ELK:

111143352

LLV:

125098568

MPUF:

101670977(CSF3R)

MNP:	132002214(CSF3R)

MLK:	131808970(CSF3R)

NVS:	122898661(CSF3R)

ORO:	101377969(CSF3R)

EJU:	114216966(CSF3R)

ZCA:	113916632(CSF3R)

MLX:	118019680(CSF3R)

NSU:	110574902(CSF3R)

LWW:	102728378 102743193(CSF3R)

FCA:	101089787(CSF3R)

PYU:	121026669(CSF3R)

PCOO:

112863097(CSF3R)

PBG:	122480290(CSF3R)

PVIV:

125173804(CSF3R)

LRUF:

124516500

PTG:	102961715(CSF3R)

PPAD:

109255488(CSF3R)

PUC:

125912766

AJU:

106973256

HHV:	120244920(CSF3R)

BTA:	132344945(CSF3R)

BOM:	102274942(CSF3R)

BIU:	109556495(CSF3R)

BBUB:

102410273(CSF3R)

BBIS:

104989482(CSF3R)

CHX:	102175546(CSF3R)

OAS:	101118070(CSF3R)

BTAX:

128045256(CSF3R)

ODA:	120856381(CSF3R)

CCAD:

122437214(CSF3R)

MBEZ:

129540790(CSF3R)

SSC:	100622336(CSF3R)

CFR:	102505807(CSF3R)

CBAI:

105072803(CSF3R)

CDK:	105086937(CSF3R)

VPC:	102527508(CSF3R)

BACU:

103000462(CSF3R)

BMUS:

118901537(CSF3R)

LVE:	103075275(CSF3R)

OOR:	101275322(CSF3R)

DLE:	111175589(CSF3R)

PCAD:

102980945(CSF3R)

PSIU:

116744796(CSF3R)

NASI:

112395487(CSF3R)

ECB:	100069253(CSF3R)

EPZ:	103549278(CSF3R)

EAI:	106830549(CSF3R)

MYB:	102241961(CSF3R)

MYD:	102764425(CSF3R)

MMYO:

118676572(CSF3R)

MLF:	102427246(CSF3R)

PKL:	118724313(CSF3R)

EFUS:

103294880(CSF3R)

MNA:	107542574(CSF3R)

DRO:	112299557(CSF3R)

SHON:

118977656(CSF3R)

AJM:	119052448(CSF3R)

PDIC:

114497355(CSF3R)

PHAS:

123831933(CSF3R)

MMF:	118626357(CSF3R)

PPAM:

129069057(CSF3R)

HAI:	109390482(CSF3R)

RFQ:	117027656(CSF3R)

PALE:

102897878(CSF3R)

PGIG:

120593303(CSF3R)

PVP:	105290707(CSF3R)

RAY:	107512067(CSF3R)

MJV:	108400801(CSF3R)

TOD:	119236146(CSF3R)

SARA:

101554763(CSF3R)

SETR:

126011721(CSF3R)

LAV:	100665706(CSF3R)

TMU:

101343066

ETF:	101655661(CSF3R)

DNM:	101437378(CSF3R)

MDO:	100031592(CSF3R)

GAS:	123243269(CSF3R)

SHR:	100928707(CSF3R)

AFZ:

127555428

PCW:	110206350(CSF3R)

OAA:	100080173(CSF3R)

GGA:	419620(CSF3R)

PCOC:

116230011(CSF3R)

MGP:	100542145(CSF3R)

CJO:	107324075(CSF3R)

TPAI:

128088349(CSF3R)

LMUT:

125703838(CSF3R)

NMEL:

110387487(CSF3R)

APLA:

101791747(CSF3R)

ACYG:

106038086(CSF3R)

CATA:

118255694(CSF3R)

AFUL:

116498034(CSF3R)

TGU:	100229496(CSF3R)

LSR:	110484278(CSF3R)

SCAN:

103822640(CSF3R)

PMOA:

120511716(CSF3R)

OTC:	121342922(CSF3R)

PRUF:

121359906(CSF3R)

GFR:	102033859(CSF3R)

FAB:	101807604(CSF3R)

OMA:	130262272(CSF3R)

PHI:	102101360(CSF3R)

PMAJ:

107214013(CSF3R)

CCAE:

111938933(CSF3R)

CBRC:

103616974(CSF3R)

ETL:	114058886(CSF3R)

ZAB:	102067746(CSF3R)

SVG:	106856103(CSF3R)

MMEA:

130582376(CSF3R)

HRT:	120763148(CSF3R)

FPG:	106112048(CSF3R)

FCH:	106630793(CSF3R)

CLV:	106145641(CSF3R)

NNI:

104017904

TALA:

116963133(CSF3R)

AFOR:

103903583(CSF3R)

ACHC:

115351446(CSF3R)

HLE:	104837087(CSF3R)

AGEN:

126046964

GCL:

127025109

SHAB:

115615890(CSF3R)

DPUB:

104307417(CSF3R)

CPEA:

104387907(CSF3R)

RTD:	128918942(CSF3R)

CUCA:

104065363(CSF3R)

BRHI:

104490204(CSF3R)

AAM:	106490870(CSF3R)

AROW:

112975657(CSF3R)

NPD:	112950823(CSF3R)

DNE:	112985221(CSF3R)

ASN:	102369421 102370521

AMJ:	102560832(CSF3R)

CPOO:

109318569(CSF3R)

GGN:	109294237(CSF3R)

PSS:	102460143(CSF3R)

CMY:	102931914(CSF3R)

CCAY:

125624640(CSF3R)

DCC:	119845398(CSF3R)

CPIC:

101942477(CSF3R)

TST:	117868289(CSF3R)

CABI:

116817035(CSF3R)

MRV:	120389303(CSF3R)

ACS:	103281080(csf3r) 103282176 103282641

ASAO:

132780375(CSF3R)

PVT:	110082761(CSF3R)

SUND:

121915885(CSF3R)

PBI:	112542138(CSF3R)

PMUR:

114922295(CSF3R)

CTIG:

120301512(CSF3R)

TSR:	106543650(CSF3R)

PGUT:

117663220(CSF3R)

APRI:

131204665(CSF3R)

PTEX:

113437695(CSF3R)

NSS:	113416023(CSF3R)

VKO:	123017849(CSF3R)

PMUA:

114601738(CSF3R)

PRAF:

128418939(CSF3R)

ZVI:	118087748(CSF3R)

HCG:	128333307(CSF3R)

GJA:	107110150(CSF3R)

STOW:

125435025(CSF3R)

EMC:	129342920(CSF3R)

XLA:	108704665 446770(csf3r.L)

XTR:	100498116(csf3r)

NPR:	108804707(CSF3R)

RTEM:

120926979(CSF3R)

BBUF:

120995299(CSF3R)

BGAR:

122932996(CSF3R)

MUO:	115480063(CSF3R)

GSH:	117365202(CSF3R)

DRE:	100134935(csf3r)

SRX:	107732744 107738609

SANH:

107661013 107679306

SGH:	107557599 107598921

CCAR:

109104913

CAUA:

113060044 113116507

CGIB:

127961904 128030085

PTET:

122360257(csf3r)

LROH:

127178430(csf3r)

OMC:	131521200(csf3r)

PPRM:

120490907 120490908

RKG:	130085717(csf3r)

MAMB:

125243268(csf3r)

CIDE:

127497497

MASI:

127452524 127453875

TROS:

130557739(csf3r)

TDW:	130433046(csf3r)

MANU:

129448403 129448463

IPU:

108269562

IFU:	128612178(csf3r)

PHYP:

113533987(csf3r)

SMEO:

124384945(csf3r)

TFD:	113644724(csf3r)

TVC:	132845753(csf3r)

AMEX:

103033065(csf3r)

CMAO:

118819067(csf3r)

EEE:	113578072(csf3r)

CHAR:

105909997(csf3r)

TRU:	101072170(csf3r)

TFS:	130532358(csf3r)

LCO:	104919598(csf3r)

NCC:

104941919

TBEN:

117468549(csf3r)

CGOB:

115021859(csf3r)

PGEO:

117461086(csf3r)

GACU:

117557246(csf3r)

EMAC:

134861625(csf3r)

ELY:	117265243(csf3r)

EFO:	125892782(csf3r)

PLEP:

121945871(csf3r)

SLUC:

116043148(csf3r)

ECRA:

117946068(csf3r)

ESP:	116690449(csf3r)

PFLV:

114557411(csf3r)

GAT:	120810150(csf3r)

PPUG:

119197914(csf3r)

AFB:	129109230(csf3r)

CLUM:

117745079(csf3r)

PSWI:

130213407(csf3r)

MSAM:

119897290(csf3r) 119918788

SCHU:

122881822(csf3r)

CUD:	121513571(csf3r)

ALAT:

119006566(csf3r)

MZE:	101478204(csf3r)

ONL:	100703184(csf3r)

OAU:	116320960(csf3r)

OLA:	101166496(csf3r)

OML:	112144040(csf3r)

CSAI:

133441087(csf3r)

XMA:	102231746(csf3r)

XCO:	114142021(csf3r)

XHE:	116717582(csf3r)

PRET:

103477807(csf3r)

PFOR:

103141547(csf3r)

PLAI:

106948807(csf3r)

PMEI:

106918290

GAF:	122831675(csf3r)

PPRL:

129371036(csf3r)

CVG:

107084721

CTUL:

119776903(csf3r)

GMU:	124865896(csf3r)

NFU:

107396619

KMR:	108235335(csf3r)

ALIM:

106524680(csf3r)

NWH:	119409928(csf3r)

AOCE:

111572351(csf3r)

MCEP:

125016938(csf3r)

CSEM:

103387876(csf3r)

POV:	109633009(csf3r)

SSEN:

122775071(csf3r)

HHIP:

117777409(csf3r)

HSP:	118113351(csf3r)

SMAU:

118308761(csf3r)

LCF:

108899580

SDU:	111235806(csf3r)

SLAL:

111661606(csf3r)

XGL:	120784673(csf3r)

HCQ:	109513114(csf3r)

SSCV:

125974980

SBIA:

133500762(csf3r)

PEE:	133401293(csf3r)

PTAO:

133479888(csf3r)

BPEC:

110174290(csf3r)

MALB:

109954603(csf3r)

BSPL:

114843611(csf3r)

SJO:	128367128(csf3r)

SASA:

100137055(csf3r)

STRU:

115177219

OTW:	112246633(csf3r)

OMY:	100136103(csf3r)

OGO:	124005719(csf3r)

ONE:

115105623

OKI:

109910102

OKE:	118367345(csf3r)

SALP:

111959064 111964732

SNH:	120031388(csf3r)

CCLU:

121555809 121586724

ELS:

105028375

SFM:	108927808(csf3r)

PKI:	111848842(csf3r)

AANG:

118210987(csf3r)

LOC:	102694353(csf3r)

PSPA:

121300512 121303348(csf3r)

ARUT:

117412732 117413588

LCM:	102353589(CSF3R)

CPLA:

HOC:

LRJ:

PJA:

Reference

PMID:2147944

Authors

Larsen A, Davis T, Curtis BM, Gimpel S, Sims JE, Cosman D, Park L, Sorensen E, March CJ, Smith CA

Title

Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.

Journal

J Exp Med 172:1559-70 (1990)
DOI:10.1084/jem.172.6.1559

Sequence

[hsa:1441]

Reference

PMID:1717255

Authors

Fukunaga R, Ishizaka-Ikeda E, Pan CX, Seto Y, Nagata S

Title

Functional domains of the granulocyte colony-stimulating factor receptor.

Journal

EMBO J 10:2855-65 (1991)
DOI:10.1002/j.1460-2075.1991.tb07835.x

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (10)   
   KEGG PATHWAY (10)   
Disease (3)   
   KEGG DISEASE (3)   
Drug (13)   
   KEGG DRUG (13)   
Gene (397)   
   KEGG GENES (377)   
   KEGG MGENES (9)   
   RefGene (7)   
   OC (4)   
Literature (2)   
   PubMed (2)   
All databases (428)   

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