ORTHOLOGY: K16421 Help
Entry
Symbol
hmaS, nocF
Name
Pathway
map01055 Biosynthesis of vancomycin group antibiotics
map01110 Biosynthesis of secondary metabolites
Reaction
R06632 4-hydroxyphenylpyruvate:oxygen oxidoreductase (decarboxylating)
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01055 Biosynthesis of vancomycin group antibiotics
K16421 hmaS, nocF; 4-hydroxymandelate synthase
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
K16421 hmaS, nocF; 4-hydroxymandelate synthase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K16421 hmaS, nocF; 4-hydroxymandelate synthase
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.46 4-hydroxymandelate synthase
K16421 hmaS, nocF; 4-hydroxymandelate synthase
Polyketide biosynthesis proteins [BR:ko01008 ]
Nonribosomal peptide tailoring proteins
Others
K16421 hmaS, nocF; 4-hydroxymandelate synthase
BRITE hierarchy
Other DBs
Genes
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Taxonomy UniProt
Reference
Authors
Hubbard BK, Thomas MG, Walsh CT
Title
Biosynthesis of L-p-hydroxyphenylglycine, a non-proteinogenic amino acid constituent of peptide antibiotics.
Journal
Sequence
Reference
Authors
Hojati Z, Milne C, Harvey B, Gordon L, Borg M, Flett F, Wilkinson B, Sidebottom PJ, Rudd BA, Hayes MA, Smith CP, Micklefield J
Title
Structure, biosynthetic origin, and engineered biosynthesis of calcium-dependent antibiotics from Streptomyces coelicolor.
Journal
Sequence
Reference
Authors
Gunsior M, Breazeale SD, Lind AJ, Ravel J, Janc JW, Townsend CA
Title
The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A.
Journal
Sequence