KEGG   ORTHOLOGY: K05060Help
Entry
K05060                      KO                                     

Name
IL6ST, GP130, CD130
Definition
interleukin 6 signal transducer
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04550  Signaling pathways regulating pluripotency of stem cells
ko04630  Jak-STAT signaling pathway
ko04659  Th17 cell differentiation
ko05167  Kaposi's sarcoma-associated herpesvirus infection
ko05200  Pathways in cancer
ko05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04630 Jak-STAT signaling pathway
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 Cellular Processes
  Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 Organismal Systems
  Immune system
   04659 Th17 cell differentiation
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
   05203 Viral carcinogenesis
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
  Infectious diseases
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IL6/12 receptor family
   K05060  IL6ST, GP130, CD130; interleukin 6 signal transducer
CD molecules [BR:ko04090]
 Proteins
  K05060  CD130, IL6ST; interleukin 6 signal transducer (gp130, oncostatin M receptor)
BRITE hierarchy
Other DBs
GO: 0004915
Genes
HSA: 3572(IL6ST)
PTR: 461866(IL6ST)
PPS: 100992032(IL6ST)
GGO: 101153224(IL6ST)
PON: 100451191(IL6ST)
NLE: 100581824(IL6ST)
MCC: 574127(IL6ST)
MCF: 101926138(IL6ST)
CSAB: 103221611(IL6ST)
RRO: 104680478(IL6ST)
RBB: 108530957(IL6ST)
CJC: 100396729(IL6ST)
SBQ: 101029979(IL6ST)
MMU: 16195(Il6st)
RNO: 25205(Il6st)
CGE: 100767181(Il6st)
NGI: 103739911(Il6st)
HGL: 101703833(Il6st)
CCAN: 109700609(Il6st)
OCU: 100349330(IL6ST)
TUP: 102494199(IL6ST)
CFA: 403545(IL6ST)
AML: 100483131(IL6ST)
UMR: 103663669(IL6ST)
ORO: 101368221(IL6ST)
FCA: 101089832(IL6ST)
PTG: 102968948(IL6ST)
AJU: 106975253(IL6ST)
BTA: 522155(IL6ST)
BOM: 102280532(IL6ST)
BIU: 109574817(IL6ST)
PHD: 102327582 102341578(IL6ST)
CHX: 102188086(IL6ST)
OAS: 101113174(IL6ST)
SSC: 100037294(IL6ST)
CFR: 102511873 102515275(IL6ST)
CDK: 105087138(IL6ST)
BACU: 103000073(IL6ST)
LVE: 103075698(IL6ST)
OOR: 101287401(IL6ST)
ECB: 100051700(IL6ST)
EPZ: 103548204(IL6ST)
EAI: 106843367(IL6ST)
MYB: 102253606(IL6ST)
MYD: 102763204(IL6ST)
HAI: 109382150(IL6ST)
RSS: 109453480(IL6ST)
PALE: 102880415(IL6ST)
LAV: 100669556(IL6ST)
TMU: 101353064
MDO: 100017284(IL6ST)
SHR: 100913307(IL6ST) 100914111
OAA: 100073530(IL6ST)
GGA: 395684(IL6ST)
MGP: 100550313
CJO: 107305990(IL6ST)
APLA: 101799928(IL6ST)
ACYG: 106035611(IL6ST)
TGU: 100226842(IL6ST)
GFR: 102036418(IL6ST)
FAB: 101807050(IL6ST)
PHI: 102107918(IL6ST)
PMAJ: 107198202(IL6ST)
CCW: 104686676(IL6ST)
FPG: 101911352(IL6ST)
FCH: 102051353(IL6ST)
CLV: 102094030(IL6ST)
EGZ: 104134682(IL6ST)
ASN: 102370521 102376353(IL6ST)
AMJ: 102559273(IL6ST)
PSS: 102460174(IL6ST)
CMY: 102933394(IL6ST)
CPIC: 101932922(IL6ST) 101952357
ACS: 100562134(il6st)
PVT: 110079290 110085393(IL6ST)
PBI: 103053185(IL6ST) 103057304
GJA: 107113291 107120496(IL6ST)
XLA: 100158347(il6st.L) 100174791(il6st.S)
XTR: 100489642(il6st)
NPR: 108792012(IL6ST)
DRE: 100006778(il6st)
TRU: 101064175(il6st)
NCC: 104952060
XMA: 102219847(il6st) 102226847
PRET: 103458450 103473124(il6st)
CSEM: 103381225 103389161(il6st)
HCQ: 109530464(il6st)
SFM: 108929965
LCM: 102356131 102357816(IL6ST)
CIN: 100135649(gp130-like)
MYI: 110463908
LAK: 106151265
 » show all
TaxonomyKoalaUniProt
Reference
PMID:2261637
  Authors
Hibi M, Murakami M, Saito M, Hirano T, Taga T, Kishimoto T
  Title
Molecular cloning and expression of an IL-6 signal transducer, gp130.
  Journal
Cell 63:1149-57 (1990)
DOI:10.1016/0092-8674(90)90411-7
  Sequence
[hsa:3572]

DBGET integrated database retrieval system