KEGG ORTHOLOGY: K05362

ORTHOLOGY: K05362

Entry

K05362                      KO

Symbol

murE

Name

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase [EC:6.3.2.7]

Pathway

map00550

Peptidoglycan biosynthesis

map01100

Metabolic pathways

Reaction

R02786

UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine gamma-ligase (ADP-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    K05362  murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins
    K05362  murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase
Enzymes [BR:ko01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.7  UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase
     K05362  murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase
Peptidoglycan biosynthesis and degradation proteins [BR:ko01011]
Precursor biosynthesis
  Amino acid ligase
   K05362  murE; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase

Other DBs

COG:

COG0769

GO:

0047482

Genes

SDO:	SD1155_07410

BACO:

BHAI:

OIH:

LSP:

LFU:	HR49_19765

LYS:	LBYS11_03725

LYB:	C3943_04735

LYZ:	DCE79_03385

LYG:	C1N55_05265

LPAK:

GDS87_04015

LAGR:

FJQ98_04825

LMAC:

I6G82_14570

LYC:	FH508_0003860

LCAP:

ICJ70_20525

LYP:	MTP04_10770(murE_1)

LIU:	OU989_03485

LLB:	R6U77_01025

VIR:	X953_06650

VIK:	KFZ58_10795

BVQ:	FHE72_08510

RMF:	D5E69_08915

RAZ:	U9J35_08545

SAU:	SA0876(murE)

SAV:	SAV1018(murE)

SAW:	SAHV_1012(murE)

SAH:	SaurJH1_1035

SAJ:	SaurJH9_1016

SAM:	MW0899(murE)

SAS:

SAS0887

SAR:	SAR0988(murE)

SAC:	SACOL1023(murE)

SAX:	USA300HOU_0976(murE1)

SAA:	SAUSA300_0919(murE)

SAO:	SAOUHSC_00954

SAE:	NWMN_0888(murE)

SAD:

SAAV_0980

SUU:	M013TW_0943

SUV:	SAVC_04255

SUE:

SAOV_0963

SUJ:	SAA6159_00874

SUK:	SAA6008_00973(murE)

SUC:	ECTR2_873(murE)

SUT:	SAT0131_01053

SUQ:	HMPREF0772_12216(murE)

SUZ:	MS7_0974(murE)

SUD:	ST398NM01_1014

SUX:	SAEMRSA15_08480(murE)

SUW:	SATW20_10150(murE)

SUG:

SAPIG1014

SUF:	SARLGA251_09330(murE)

SAUA:

SAAG_02127

SAUE:

RSAU_000903(murE)

SAUN:

SAKOR_00936

SAUS:

SA40_0888(murE)

SAUU:

SA957_0903(murE)

SAUG:

SA268_0905(murE)

SAUZ:

SAZ172_0959(murE)

SAUT:

SAUJ:

SAUK:

SAUQ:

SAUV:

SAI7S6_1007210(murE)

SAUW:

SAI5S5_1007170(murE)

SAUX:

SAI6T6_1007180(murE)

SAUY:

SAI8T7_1007210(murE)

SAUF:

X998_1016

SAB:	SAB0884(murE)

SUY:	SA2981_0972(murE)

SAUB:

C248_1042(murE)

SAUM:

BN843_9230

SAUC:

CA347_935(murE)

SAUR:

SABB_00986(murE)

SAUI:

AZ30_04840

SAUD:

CH52_00795

SAMS:

NI36_04845

SUH:	SAMSHR1132_08650

SER:	SERP0607(murE)

SEP:

SE_0718

SEPP:

SEB_00697

SEPS:

DP17_2003(murE)

SHA:	SH1941(murE)

SHH:	ShL2_01803(murE)

SSP:

SSP1767

SCA:	SCA_0621(murE)

SLG:	SLGD_01850

SLN:	SLUG_18440(murE)

SSD:	SPSINT_0714

SDT:	SPSE_1819(murE)

SDP:	NCTC12225_02039(murE)

SWA:	A284_08685

SPAS:

STP1_2087

SXY:	BE24_02440

SXL:	SXYLSMQ121_1766

SXO:	SXYL_01914(murE)

SHU:	SHYC_09250(murE-2)

SCAP:

AYP1020_0275(murE)

SSCH:

SSCZ:

SAGQ:

SEQO:

SSIF:

SCV:	A4G25_04830

SPET:

CEP67_11885

SLZ:	B5P37_09085

SCOH:

BZ166_00755

SNL:	BJD96_09795

SKL:	C7J89_10925

SFQ:	C7J90_06800

SHOM:

EGX58_01800(murE)

SMUS:

C7J88_10310

SCAR:

DWB96_09560(murE)

SCHR:

DWB92_09015(murE)

SARL:

SAP2_18050(murE)

SPIC:

SAMEA4384060_1942(murE)

SSH:	NCTC13712_00961(murE)

SSIM:

SAMEA4384339_0867(murE)

SDB:	CNQ82_04845(murE)

SLLO:

SAUL:

SSAC:

SRAI:

SPSD:

STAS:

SURY:

SEDA:

SCAQ:

SDEV:

SROT:

STAP:

SSCU:

SFF:	FOB90_10775

SSTE:

SAMEA4384403_1838(murE)

MLEN:

H3V22_13400

MVT:	I6J10_02135

MACR:

MARY:

MBRU:

MEPI:

MEQU:

MBOC:

MCL:	MCCL_0631(murE)

MCAK:

MCCS_08580(murE)

MBOE:

HT586_04535

SHV:	AAT16_03595

JEA:	JEM45_04525

NAMP:

KPF49_02030

NMY:	CJ229_008575

SBAC:

BVH56_06325

GOT:	AXE85_03625

GMO:	NCTC11323_01073(murE)

GEQ:	CG018_05765

GSA:	FOC50_07515

GHA:	NCTC10459_00697(murE)

SIV:

SSIL_3199

SSIL:

SOLI23_02570

SOB:	CSE16_03405

PLN:	Plano_2069

PKU:	AUO94_05340

PRT:	AUC31_16570

PLL:	I858_012485

PANA:

BBH88_08720

PDG:	BCM40_04900

PHC:	BBI08_07600

PMAR:

B0X71_12800

PPLA:

BBI15_06065

PFAE:

AJGP001_12205

PLX:	CW734_12065

PMAT:

BBI11_11520

PDEC:

H1Q58_10780

JEO:

JMA_14530

KUR:	ASO14_2324(murE)

KZO:	NCTC404_00255(murE)

SPSY:

SPOR:

SPOP:

SURE:

SPOS:

SPAE:

SPOO:

SURL:

RST:	ATY39_01725

PAEK:

D3873_03840

PANC:

E2636_11030

PLAY:

DNR44_009310

VIJ:	JNUCC6_18910

UTH:	DKZ56_06045

LLK:	LLKF_1979(murE)

LLT:	CVCAS_1739(murE)

LLS:	lilo_1789(murE)

LLD:	P620_10210

LLX:	NCDO2118_1912(murE)

LLJ:	LG36_1762(murE)

LLC:

LACR_1987

LLR:

llh_3110

LLN:	LLNZ_10265(murE)

LLI:	uc509_1759(murE)

LLW:	kw2_1860(murE)

LGR:

LCGT_0383

LGV:

LCGL_0383

LPK:	LACPI_2096(murE)

LRN:	CMV25_06495

LACT:

D7I46_06865(murE)

LTI:	JW886_08480

LPAA:

BHS01_09930

LPET:

lgb_00390(murE)

LFO:	LMK00_01935

SPY:	SPy_0388(murE)

SPZ:	M5005_Spy0325(murE)

SPYM:

M1GAS476_0392(murE)

SPYA:

A20_0373c(murE)

SPM:	spyM18_0440(murE)

SPG:	SpyM3_0284(murE)

SPS:

SPs1575

SPH:	MGAS10270_Spy0320(murE)

SPI:	MGAS10750_Spy0321(murE)

SPJ:	MGAS2096_Spy0343(murE)

SPK:	MGAS9429_Spy0324(murE)

SPF:	SpyM51533(murE)

SPA:	M6_Spy0351

SPB:	M28_Spy0314(murE)

STG:	MGAS15252_0351(murE.1)

STX:	MGAS1882_0351(murE.1)

SOZ:	Spy49_0319c(murE)

STZ:	SPYALAB49_000354(murE)

SPYH:

L897_01765

SPN:	SP_1530(murE)

SPD:	SPD_1359(murE)

SPR:	spr1384(murE)

SPW:	SPCG_1517(murE)

SJJ:

SPJ_1434

SNV:	SPNINV200_13670(murE)

SPX:	SPG_1456(murE)

SNT:

SPT_1468

SND:

MYY_1460

SPNN:

T308_06950

SNE:	SPN23F14930(murE)

SPV:

SPH_1643

SNC:	HMPREF0837_11764(murE)

SNM:	SP70585_1569

SPP:

SPP_1552

SNI:	INV104_13020(murE)

SPNG:

HMPREF1038_01514

SNB:	SP670_1613

SNP:

SPAP_1552

SNX:	SPNOXC13410(murE)

SNU:	SPNA45_00691(murE)

SPNE:

SPN034156_04290(murE)

SPNU:

SPN034183_13400(murE)

SPNM:

SPN994038_13290(murE)

SPNO:

SPN994039_13300(murE)

SAG:	SAG1391(murE)

SAN:

gbs1461

SAK:	SAK_1424(murE)

SGC:	A964_1305(murE)

SAGS:

SaSA20_1131(murE)

SAGL:

GBS222_1144(murE)

SAGM:

SAGI:

SAGR:

SAGP:

SAGC:

SAGT:

SAGE:

SAGG:

SAGN:

W903_1407(murE)

SAGJ:

ID870_02680

SMU:	SMU_1677(murE)

SMC:	SmuNN2025_0440(murE)

SMUT:

SMUGS5_07580

SMJ:	SMULJ23_0456(murE)

SMUA:

SMUFR_1459

STC:	str0349(murE)

STL:	stu0349(murE)

STE:

STER_0387

STN:

STND_0341

STU:	STH8232_0447(mure)

STW:

Y1U_C0334

STHE:

T303_02880

STHS:

AVT04_03150

SSA:	SSA_1739(murE)

SSB:	SSUBM407_1216(murE)

SSU:	SSU05_0651

SSV:	SSU98_0652

SSI:	SSU0608(murE)

SSS:	SSUSC84_0581(murE)

SSF:	SSUA7_0606(murE)

SSW:	SSGZ1_0642

SUP:

YYK_02890

SSUS:

NJAUSS_0712

SST:	SSUST3_0812(murE)

SSUY:

YB51_4025

SSK:	SSUD12_1217(murE)

SUI:	SSUJS14_0741(murE)

SUO:	SSU12_0607(murE)

SRP:	SSUST1_1159(murE)

SSUT:

TL13_1126(murE)

SSUI:

T15_1332(murE)

SGO:	SGO_1638(murE)

SEZ:	Sez_1617(murE)

SEQ:

SZO_03550

SEZO:

SeseC_02166(murE)

SEQU:

Q426_00770

SEU:

SEQ_1835

SUB:	SUB0425(murE)

SDS:	SDEG_0435(murE)

SDG:	SDE12394_02090

SDA:	GGS_0424(murE)

SDC:	SDSE_0454(murE)

SDQ:	SDSE167_0474(murE)

SGA:	GALLO_1770(murE)

SGG:	SGGBAA2069_c17290(murE)

SGT:	SGGB_1757(murE)

SMB:	smi_1512(murE)

SOR:	SOR_0659(murE)

STK:

STP_1332

STB:	SGPB_1578(murE.2)

SCP:	HMPREF0833_10974(murE)

SCF:	Spaf_1551(murE2)

SSR:	SALIVB_0346(murE)

STF:	Ssal_01844(murE)

STJ:	SALIVA_0324(murE)

STRS:

SSAL8618_01905

SSAH:

HSISS4_00276(murE)

STD:	SPPN_07500

SMN:	SMA_1676(murE)

SIF:	Sinf_1499(murE)

SIE:	SCIM_0429(murE)

SIB:	SIR_1231(murE)

SIU:	SII_1255(murE)

SANG:

SAIN_0463(murE)

SANC:

SANR_0481(murE)

SANS:

DK43_07865

SCG:	SCI_0511(murE)

SCON:

SCRE_0491(murE)

SCOS:

SCR2_0491(murE)

SOI:	I872_05895

SIK:

K710_1552

SIQ:	DQ08_07240

SIO:	DW64_07225

SIZ:	SI82_07345

SLU:

KE3_1632

SIG:	N596_04825

SIP:	N597_06680

STV:	V470_02995

SPAT:

A0O21_01685

STRA:

ATM98_04500

STRN:

SNAG_0628(murE)

SSOB:

DK181_08630(murE)

SRQ:	SR187_6770

SEQI:

A6J79_04620(murE)

SKI:	D7D50_05820(murE)

SPEI:

EHW89_02275(murE)

SRAT:

FY406_06125

SGW:	D7D53_05730(murE)

SPLR:

C0J00_02250

STRG:

SRT_04560(murE)

SVB:	NCTC12167_00375(murE_1)

SMEN:

SAMEA4412692_1073(murE)

SFER:

NCTC12278_01481(murE)

SCAI:

NCTC12191_00119(murE)

SPSU:

NCTC13786_01732(murE)

SCHJ:

DDV21_008855(murE)

SPOC:

NCTC10925_01423(murE)

SPAB:

KQ224_10235

SLAT:

J4854_08020

SAUP:

NCTC3168_01256(murE)

SURN:

NCTC13766_01698(murE)

SACO:

SAME_00581(murE_1)

SVF:	NCTC3166_01492(murE)

SOS:	INT76_03075

STOY:

STYK_14530(murE)

SRUM:

GPZ88_02250

SACY:

O6R09_07245

SMIE:

NCTC11169_00434(murE)

SRUN:

LPB404_08075

FPEN:

KIW23_09135

LMU:	LBLM1_00055

LVA:	LV515_09230(murE)

LPON:

LP475_08555(murE)

LGAS:

LG045_09270(murE) LG045_09275(murE)

LPOR:

PRK60_09190(murE)

LNN:	F0161_11015(murE)

EFA:	EF0668(murE)

EFL:	EF62_1038(murE)

EFI:	OG1RF_10399(murE)

EFD:	EFD32_0482

EFS:	EFS1_0515(murE)

EFN:	DENG_00697(murE)

EFQ:	DR75_2617(murE)

EFC:	EFAU004_02569

EFAU:

EFAU085_02652

EFU:	HMPREF0351_12511(murE2)

EFM:

M7W_2527

EFT:	M395_11930

EHR:

ECAS:

EMU:

EDU:

EGA:	AL523_03305

ESS:	ATZ33_15015

ETH:	CK496_11385

EGV:	EGCR1_10725(murE)

EAV:	EH197_22045(murE)

ESG:	EsVE80_02820(murE2)

ELAC:

I4Q40_11975

ECEC:

NCTC12421_02150(murE)

ERAF:

J9537_12845

EIE:	ENLAB_14990(murE_2)

EDS:	PML78_06265

EMS:	P3T75_11975

MPS:

MPTP_1715

MPX:

MPD5_0348

THL:	TEH_01090(murE)

TEY:	GLW17_06280(murE)

TOO:	C7K38_03850

TKR:	C7K43_09960

VTE:	BHY08_05245

VPI:	BW732_00325

VAC:	E4Z98_04960(murE)

VAO:	FA707_05565(murE)

VAH:	G7081_05755

VCP:	H9L18_08285

VHY:	G7082_12370

VFV:	K5K99_09460

VLU:	M2919_01605(murE)

VLC:	G314FT_15050(murE)

VIE:	OL234_05105

AUI:	APT62_06795

ACG:	AWM71_05850

AVS:	AWM76_03400

AUH:	AWM75_06455

ALOY:

CJ190_002905

AMIT:

DBT49_0003325

ATJ:	DBT50_009000(murE)

CML:	BN424_209(murE)

CARN:

FPV25_04635(murE)

DPM:	FNV33_08880(murE)

DINC:

QNK01_07860

FSA:	C5Q98_01550

LASA:

L9O85_14680(argB)

PALM:

RBG61_09480

IBU:	IB211_00151

COO:

CCU_09610

CCOM:

I6K69_13995

CEV:	LK421_04065 LK421_09800

QDO:	H9Q78_12455

WHJ:	H9Q79_08600(murE)

SMOE:

RGT18_02270

OLO:	ADJ70_02405

TIO:	INP52_09145

CGO:	Corgl_0162

COLL:

KPC83_01475

BDE:	BDP_1522(mur)

BDN:

BBDE_1446

BSUE:

BS3272_03770

» show all

Reference

Authors

Triolo TA, Chabin RM, Pompliano DL

Title

Cloning, expression and characterization of the Streptococcus pyogenes murE gene encoding a UDP-MurNAc-l-alanyl-d-glutamate: l-lysine ligase

Journal

Enzyme Microb Technol 35:300-308 (2004)
DOI:10.1016/j.enzmictec.2004.03.020

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
   KEGG RCLASS (2)   
Gene (1320)   
   KEGG GENES (458)   
   KEGG MGENES (850)   
   RefGene (8)   
   OC (4)   
All databases (1333)   

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