KEGG   ORTHOLOGY: K10030Help
Entry
K10030                      KO                                     

Name
IL8, CXCL8
Definition
interleukin 8
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04062  Chemokine signaling pathway
ko04064  NF-kappa B signaling pathway
ko04072  Phospholipase D signaling pathway
ko04218  Cellular senescence
ko04620  Toll-like receptor signaling pathway
ko04621  NOD-like receptor signaling pathway
ko04622  RIG-I-like receptor signaling pathway
ko04657  IL-17 signaling pathway
ko04932  Non-alcoholic fatty liver disease (NAFLD)
ko04933  AGE-RAGE signaling pathway in diabetic complications
ko05120  Epithelial cell signaling in Helicobacter pylori infection
ko05131  Shigellosis
ko05132  Salmonella infection
ko05133  Pertussis
ko05134  Legionellosis
ko05142  Chagas disease (American trypanosomiasis)
ko05144  Malaria
ko05146  Amoebiasis
ko05160  Hepatitis C
ko05161  Hepatitis B
ko05164  Influenza A
ko05167  Kaposi's sarcoma-associated herpesvirus infection
ko05200  Pathways in cancer
ko05202  Transcriptional misregulation in cancer
ko05219  Bladder cancer
ko05323  Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:ko00001]
 Environmental Information Processing
  Signal transduction
   04064 NF-kappa B signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04072 Phospholipase D signaling pathway
    K10030  IL8, CXCL8; interleukin 8
  Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K10030  IL8, CXCL8; interleukin 8
 Cellular Processes
  Cell growth and death
   04218 Cellular senescence
    K10030  IL8, CXCL8; interleukin 8
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04621 NOD-like receptor signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04622 RIG-I-like receptor signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04657 IL-17 signaling pathway
    K10030  IL8, CXCL8; interleukin 8
   04062 Chemokine signaling pathway
    K10030  IL8, CXCL8; interleukin 8
 Human Diseases
  Cancers
   05200 Pathways in cancer
    K10030  IL8, CXCL8; interleukin 8
   05202 Transcriptional misregulation in cancers
    K10030  IL8, CXCL8; interleukin 8
   05219 Bladder cancer
    K10030  IL8, CXCL8; interleukin 8
  Immune diseases
   05323 Rheumatoid arthritis
    K10030  IL8, CXCL8; interleukin 8
  Endocrine and metabolic diseases
   04932 Non-alcoholic fatty liver disease (NAFLD)
    K10030  IL8, CXCL8; interleukin 8
   04933 AGE-RAGE signaling pathway in diabetic complications
    K10030  IL8, CXCL8; interleukin 8
  Infectious diseases
   05120 Epithelial cell signaling in Helicobacter pylori infection
    K10030  IL8, CXCL8; interleukin 8
   05132 Salmonella infection
    K10030  IL8, CXCL8; interleukin 8
   05131 Shigellosis
    K10030  IL8, CXCL8; interleukin 8
   05133 Pertussis
    K10030  IL8, CXCL8; interleukin 8
   05134 Legionellosis
    K10030  IL8, CXCL8; interleukin 8
   05164 Influenza A
    K10030  IL8, CXCL8; interleukin 8
   05161 Hepatitis B
    K10030  IL8, CXCL8; interleukin 8
   05160 Hepatitis C
    K10030  IL8, CXCL8; interleukin 8
   05167 Kaposi's sarcoma-associated herpesvirus infection
    K10030  IL8, CXCL8; interleukin 8
   05146 Amoebiasis
    K10030  IL8, CXCL8; interleukin 8
   05144 Malaria
    K10030  IL8, CXCL8; interleukin 8
   05142 Chagas disease (American trypanosomiasis)
    K10030  IL8, CXCL8; interleukin 8
Cytokines and growth factors [BR:ko04052]
 Cytokines
  Chemokines
   K10030  IL8, CXCL8; interleukin 8
Glycosaminoglycan binding proteins [BR:ko00536]
 Heparan sulfate/Haparin
  Chemokines
   K10030  IL8, CXCL8; interleukin 8
BRITE hierarchy
Other DBs
GO: 0005153
Genes
HSA: 3576(CXCL8)
PTR: 471205(CXCL8)
PPS: 100978369(CXCL8)
GGO: 101130732(CXCL8)
PON: 100437111 100437488
NLE: 100586157(CXCL8)
MCC: 613028(CXCL8)
MCF: 102127272(CXCL8)
CSAB: 103235786(CXCL8)
RRO: 104658873(CXCL8)
RBB: 108523449(CXCL8)
CJC: 100390587(CXCL8)
SBQ: 101049298(CXCL8)
NGI: 103742429(Cxcl8)
HGL: 101707734(Cxcl8)
CCAN: 109691927(Cxcl8)
OCU: 100009129(CXCL8)
TUP: 102471344(CXCL8)
CFA: 403850(CXCL8)
AML: 100472054(CXCL8)
UMR: 103665307(CXCL8)
ORO: 101365039(CXCL8)
FCA: 493836(CXCL8)
PTG: 102953024(IL8) 102953898
AJU: 106981787 106982166(CXCL8)
BTA: 100847175 280828(CXCL8)
BOM: 102268124(CXCL8)
BIU: 109560570(CXCL8) 109560575
PHD: 102343666(CXCL8) 102344032
CHX: 102178438(CXCL8)
OAS: 101112402 443418(CXCL8)
SSC: 396880(CXCL8)
CFR: 102506409(CXCL8)
CDK: 105091344(CXCL8)
BACU: 103006782(CXCL8)
LVE: 103086219(CXCL8)
OOR: 101278129(CXCL8)
ECB: 100037400(CXCL8)
EPZ: 103566768(CXCL8)
EAI: 106835113(CXCL8)
MYB: 102243203(CXCL8)
MYD: 102761051(CXCL8)
HAI: 109394819(CXCL8)
RSS: 109439832(CXCL8)
PALE: 102892534(CXCL8)
LAV: 100664099(CXCL8)
TMU: 101358515
MDO: 100023722(IL8)
SHR: 100933600(CXCL8)
OAA: 103170567
GGA: 395872(IL8L1) 396495(IL8L2)
MGP: 100034742(IL8) 100546187
CLV: 102090447(IL-8) 102094827
AMJ: 102567477(CXCL8) 102567713 102568190(IL8L1) 102574675(IL8)
CPIC: 101952445(CXCL8)
ACS: 100563503
PBI: 103060378
GJA: 107114920
DRE: 100002946(cxcl8a) 100003859(cxcl8b.3)
TRU: 105418180 445923(il8)
 » show all
TaxonomyKoalaUniProt
Reference
PMID:1639201
  Authors
Baggiolini M, Clark-Lewis I
  Title
Interleukin-8, a chemotactic and inflammatory cytokine.
  Journal
FEBS Lett 307:97-101 (1992)
DOI:10.1016/0014-5793(92)80909-Z
  Sequence
[hsa:3576]

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