KEGG   Loxodonta africana (African savanna elephant): 100653677
Entry
100653677         CDS       T04351                                 
Symbol
MSH2
Name
(RefSeq) DNA mismatch repair protein Msh2
  KO
K08735  DNA mismatch repair protein MSH2
Organism
lav  Loxodonta africana (African savanna elephant)
Pathway
lav01524  Platinum drug resistance
lav03430  Mismatch repair
lav05200  Pathways in cancer
lav05210  Colorectal cancer
Brite
KEGG Orthology (KO) [BR:lav00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03430 Mismatch repair
    100653677 (MSH2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100653677 (MSH2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    100653677 (MSH2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    100653677 (MSH2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:lav03400]
    100653677 (MSH2)
DNA repair and recombination proteins [BR:lav03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   MMR (mismatch excision repair)
    Mismatch and loop recognition factors
     100653677 (MSH2)
SSDB
Motif
Pfam: MutS_V MutS_III MutS_II MutS_IV MutS_I AAA_27
Other DBs
NCBI-GeneID: 100653677
NCBI-ProteinID: XP_023413028
Position
Unknown
AA seq 871 aa
MFFFPPLGAKTLESVVLSKMNFESFVKGLLLVRQYRVEVYKNKAGNKASKENDWYLAFKA
SPGNLSQFEDILFGNNDMSSSIGVVGIKISVVDGQRQVGVGYVDSIQRKLGLCEFPDNDQ
FSNLEALLVQIGPKECVLPGGETTGDMGKLRQIILRGGILITDRKRAEFSAKDIYQDLNR
LLKAKKGEQMNSAVLPEMENQVAVASLSAVIKFLELLSDDSNFGQFELTTFDFNQYMKLD
IAAVRALNLFQGSLEDTTGSQSLAGLLNKCKTPQGQRLVNQWIKQPLMDKNRIEERLNLV
EAFVEDAELRQILQEDLLRRFPDLNRLAKKFQRQAANLQNCYQVYQGVNQLPNVIQALEK
YEGKHQSLLLAIFVTPLVDLRSDFSKFQEMIETTLDMDQVENHEFLVKPSFDPNLTELRE
VMDDLEKKMQSTLTGAARDLGLEPGKQIKLDSSAQFGYYFRVTCKEEKVLRNNKNFTIVD
IQKNGVKFANSKLTSLNEEYTKNKTEYEEAQNAIVKEIINISSGYVEPMQTLNDVLAQLD
AVVSFAHVSNGAPVAYVRPVILEKGRGRILLTASRHACVEVQDEVAFIPNDVHFEKDKQM
FHIITGPNMGGKSTYIRQTGVIVLMAQIGCFVPCESAEVSIVDCILARVGAGDSQLKGVS
TFMAEMLETASILRSATKDSLIIIDELGRGTSTYDGFGLAWAISEYIATRIGAFCMFATH
FHELTALADQIPTVNNLHVTALTTEETLTMLYQVKKGVCDQSFGIHVAELASFPRHVIEC
AKQKALELEEFQNIGKSQDYGETEPAAKRCYLEREQGEKIIQEFLSKVKQVPFTTMSEGD
ITMKLKQLKAEVIAKNNGFVNEIISRIKVTT
NT seq 2616 nt   +upstreamnt  +downstreamnt
atgtttttttttccccctttaggagcaaagactctggagagtgttgtgcttagtaaaatg
aattttgagtcttttgtaaaaggtcttcttctagtccgtcagtatagagttgaagtttat
aagaataaagctggaaataaggcctccaaggagaatgattggtatttggcatttaaggct
tctccaggtaatctttcacagtttgaagacattctgtttggtaacaatgatatgtcgtcg
tccattggagttgtgggtattaaaatatccgtagttgacggccaaagacaagttggcgtt
gggtatgttgactccatccagaggaagctaggactgtgcgagttccctgataatgatcag
ttctccaatcttgaagctctcctggttcagattggacccaaggaatgcgttttaccagga
ggagagactaccggagacatgggaaaactgaggcagattattctgagaggagggattctg
atcacagacagaaaaagagctgaattttccgcaaaagacatttatcaggatctcaaccgg
ttgttgaaagccaaaaagggagaacagatgaatagtgctgtcttgccagaaatggagaat
caggtcgcagttgcatcgttgtctgcagtaatcaagtttttagaactcttatcagatgat
tcaaactttggacagtttgaactgactacttttgacttcaaccagtacatgaaattggat
attgccgcagtccgagcccttaaccttttccagggttctcttgaagataccacaggctct
cagtctctggccggattgctgaataaatgcaaaacccctcaaggacaaagattggttaat
cagtggattaagcagccgctcatggataagaacagaatagaagagagattaaatttagtg
gaagcctttgtagaagacgcagaattgaggcaaatcttacaagaagatttacttcgtcga
ttcccagatctgaaccgacttgctaagaaatttcaaagacaagcagcaaacttacaaaac
tgttaccaagtctaccagggtgtaaatcaactccctaacgttatacaggctctggaaaaa
tatgaaggaaaacaccagtccttgttgttggccatttttgtgacccctcttgtcgatctt
cgttccgatttctccaagtttcaggaaatgatagaaacaactttagacatggatcaggtg
gaaaaccatgaattccttgtaaaaccctcttttgatcctaatctgactgaactaagagaa
gtgatggatgacttggaaaagaagatgcagtcaacattaacaggcgcagccagagaccta
ggcttggagcctggcaagcagattaaactggattccagtgcacagtttggatattacttt
cgagtaacctgtaaggaagaaaaagtccttcgtaataataaaaacttcaccatagtagat
atccagaagaatggtgttaaatttgccaacagtaaattgacttctctcaatgaagagtat
accaaaaataaaactgagtacgaggaagcccagaatgccattgtgaaggaaatcatcaac
atttcttcaggctacgtagaaccgatgcagaccctcaacgatgtgttagctcagctggat
gccgtcgtcagctttgctcacgtctcaaatggagcccctgttgcgtacgtacgaccggtc
attttggagaagggacgaggaagaattctgttgacagcatctagacatgcttgtgttgaa
gttcaagatgaagttgcctttattcccaatgatgttcactttgagaaagataaacagatg
ttccacatcattactggccccaatatgggaggtaaatcaacatatattcgccaaaccggg
gtgatagttctcatggcgcagattgggtgtttcgtgccatgcgagtcggcagaagtgtcc
attgtggactgcatcttggctcgggtaggggctggtgacagtcaattgaaaggagtctcc
acgttcatggctgaaatgttagaaactgcttctattctcaggtctgccaccaaagactcg
ttaataatcatagatgagttgggaagaggaacctcaacctacgatggatttgggttggcg
tgggccatatcagagtacattgccacaaggattggtgccttttgcatgtttgcaacccat
tttcatgaacttactgccttggccgatcagataccaactgtcaataatctgcatgtcaca
gcactgaccactgaagagaccctaactatgctttatcaggtgaagaaaggtgtctgtgat
caaagttttgggattcacgtggcggaacttgctagtttccccaggcacgtaatagagtgt
gctaaacaaaaagccctggagctggaggagtttcagaatattggaaaatctcaagactat
ggtgaaacagaaccagcagcaaaacgatgctatctggaaagagagcaaggtgaaaaaatt
attcaggagtttctgtccaaggtgaagcaagtgccctttaccacaatgtcagaaggagac
atcacaatgaagttgaaacagctgaaagctgaggtgatagcaaagaataatggttttgta
aatgaaatcatttcacgaataaaggttactacataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (30)   

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