KEGG   Mus caroli (Ryukyu mouse): 110297443
Entry
110297443         CDS       T05910                                 
Symbol
Arhgef1
Name
(RefSeq) rho guanine nucleotide exchange factor 1 isoform X3
  KO
K12330  Rho guanine nucleotide exchange factor 1
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal04270  Vascular smooth muscle contraction
mcal04611  Platelet activation
mcal04810  Regulation of actin cytoskeleton
mcal04928  Parathyroid hormone synthesis, secretion and action
mcal05135  Yersinia infection
mcal05163  Human cytomegalovirus infection
mcal05200  Pathways in cancer
mcal05205  Proteoglycans in cancer
mcal05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    110297443 (Arhgef1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110297443 (Arhgef1)
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    110297443 (Arhgef1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    110297443 (Arhgef1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110297443 (Arhgef1)
   05205 Proteoglycans in cancer
    110297443 (Arhgef1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    110297443 (Arhgef1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    110297443 (Arhgef1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110297443 (Arhgef1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mcal04131]
    110297443 (Arhgef1)
Membrane trafficking [BR:mcal04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    110297443 (Arhgef1)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PH_13 AbiJ_NTD3
Other DBs
NCBI-GeneID: 110297443
NCBI-ProteinID: XP_021021851
Ensembl: MGP_CAROLIEiJ_G0029351
UniProt: A0A6P5PYN1
Position
7:24173633..24193910
AA seq 976 aa
MGEVAGGAAPGPPRSGLVSIIIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMAL
LQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPNVAFEL
DRTRPDLISEDVQRRFIQEVVQSQQTAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKD
RGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVRTKSGDKKSGR
NFFRKKVMGNRRSDEPPKTKKGLSSILDPARWNRGEPSAPDCRHLKVEADAEKPGPADRK
GGLGMSSRDRTVGTPGQDNPGVSLHPLSTDSVDSREPGVDTPQEPGDTPPQGPTSLEPLA
PPESTEDNGETERLSGRLGRSESLRVSDRRRPSRGSLGAKGRGGGRSRSDVDMDPGSATA
VLGPTRRATPEPGDDGEPGRSGLELEPEEPPGWRELVPPDTLLSLPKSQVKRQEVISELL
VTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFPSLDELIEVHSLFLDRLMKRRQES
GYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQEAES
RPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEESTERGKVELAAECCREILHHVNQA
VRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKDKAIE
VHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATDHKAF
YVIFTWDQEAQIYELVAQTSSERKNWCTLITETAGSLKVPAPASRLKPRPSPSSIREPLL
SSSENGTGGTEMAPADARTERLLNDLLPFCRPGPEGQLAATALQKVLSLKQILLSTEEDS
GAGPPRDGDGVPGGGAPGPAHTQEVEENLLSLEVTIRQLEELEEEFCRLRPLLSQLGGTL
SPNLAAPERSAQTGLS
NT seq 2931 nt   +upstreamnt  +downstreamnt
atgggagaagtcgccggaggggcggccccagggcctccccggtctggcctggtgtccatc
atcatcggggcggaggatgaggattttgagaacgagctggaggcgaactcagaagatcaa
aacagccagttccagagcctggagcaagtgaagcgccgccctgcccaccttatggccctc
ctgcagcatgtggccctgcagtttgagccaggaccgctgctctgctgcctgcatgcagac
atgctgagctctctgggccccaaagaagccaagaaggccttcctcgacttctatcacagt
ttcctggagaagactgcggttctccgggtgccggtccctcccaatgtcgcttttgaactt
gatcgtactcggcctgatctgatctctgaggatgtccagaggcggttcatacaagaggta
gtgcagagccagcagacagccgtgagccgtcagctagaggacttccgctccaagcggctc
atgggcatgacgccctgggagcaggaactgagcctgctggagccctggattgggaaagac
cgaggcaactatgaagcccgggagcggcatgttgcggagcggctgctgtcccacctggag
gagacccagcataccatctctacagatgaagagaaaagtgctgctgtggtcactgccatc
agcctgtatatgcgccaccttggagtccggaccaagagtggggacaagaagtcgggaagg
aacttcttccggaaaaaggtgatggggaatcggaggtcagatgaacccccaaagacaaag
aaagggctgagcagtatcctagatcctgcacgttggaaccggggagagccatctgctcca
gattgtcgacatctaaaggtcgaagctgatgcagagaagccaggccctgcagaccggaag
ggaggcctgggtatgtcttctcgggacaggactgttgggactcctggacaggacaaccca
ggagtctccctgcaccctctgtctacagacagcgtcgactcccgggaaccaggtgtggat
accccgcaggagccaggggacacacccccacagggccctaccagcctggagcccctggcg
cccccagagagcacagaggacaatggcgagactgagaggctatcagggcgtctgggacgc
tcagagagcctgcgggtgagtgaccgccgccggccttcccggggcagcctcggggctaag
ggccggggtgggggccgttcccggagcgacgtggacatggacccgggctccgccacggcc
gtgcttggccccacccgacgagccacccctgagcccggagatgatggggagccaggacgg
tcaggcctggaactggaaccagaagaacctcctgggtggagggaactcgtgcccccagac
accctgctcagtctgcccaagagccaagtgaagcggcaggaggtcatcagcgagctgctc
gtgacggaggcagctcacgtgcgcatgctacgggtactgcatgacctcttctaccagccc
atggcggatggaggcttcttccctctggacgagctgcagaacatcttcccgagcctggat
gagcttatcgaggtgcactccctgttcctcgatcgcttgatgaagcggagacaagagagt
ggctacctcattgaggagattggcgatgtgctactggcccggttcgatggcgctgagggc
tcatggttccagaagatctcctcccgcttctgcagccgccagtcattcgctctagagcag
ctcaaagccaagcagcgcaaggagcctcggttctgtgcctttgtgcaggaagctgagagc
cgcccgagatgccggcgcctacagttaaaggacatgatccccaccgagatgcagcgactg
accaagtacccactgctgctacagagcatcgggcagaacacagaggagtctacagaacga
gggaaagtggagcttgcagctgagtgctgccgggagattctgcaccatgtcaatcaagcc
gtccgtgacatggaggacctgctgcggctcaaggattaccagcggcgcctggacttgact
cacctacggcagagcagtgaccctatgctgagcgagttcaagaacctggacatcactaag
aagaagttggtccatgaaggccccctcacgtggcgagtgaccaaagacaaagctatagaa
gtgcacgtgctcttgctggacgacctactgctgctgctccagcgccaggacgagaggctg
ctgctcaagtcccacagccggacgctgacacccacccctgacggcaaaactatgctgcgg
ccggtgctccggctcacctctgccatgacccgagaggtggccactgatcacaaagctttc
tacgtcatttttacctgggaccaggaggcccagatatatgagctggtggcacagacatcg
tcggaacgcaaaaactggtgtaccctcatcactgagactgctggatccctgaaggtccct
gcccctgcctcccgcctcaaaccccggcccagcccaagcagcatccgagaacctctgctc
agcagctctgagaatggcactggaggcacagagatggctccagctgatgccaggacagag
cggctcctcaacgacctcctgcccttctgcagaccaggcccagagggccagcttgctgcc
acagcccttcagaaagtactgtccctgaagcagatcctgttaagcactgaggaagacagt
ggagcagggcctccccgcgatggggatggggtgcctggtggtggggcccccggcccagcg
cacacccaggaggttgaggaaaacctgcttagcttagaggtgaccatcagacaactggag
gagctggaagaggaattttgtcgcctaagacccctcctgtctcagcttggggggactctg
tcccccaacctggctgcacctgaacgctctgctcagacaggcctttcatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (5)   
   Pfam (5)   
All databases (36)   

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