KEGG   Mus caroli (Ryukyu mouse): 110306746
Entry
110306746         CDS       T05910                                 
Symbol
Hif1a
Name
(RefSeq) hypoxia-inducible factor 1-alpha isoform X5
  KO
K08268  hypoxia-inducible factor 1 alpha
Organism
mcal  Mus caroli (Ryukyu mouse)
Pathway
mcal04066  HIF-1 signaling pathway
mcal04137  Mitophagy - animal
mcal04140  Autophagy - animal
mcal04148  Efferocytosis
mcal04659  Th17 cell differentiation
mcal04919  Thyroid hormone signaling pathway
mcal05167  Kaposi sarcoma-associated herpesvirus infection
mcal05200  Pathways in cancer
mcal05205  Proteoglycans in cancer
mcal05208  Chemical carcinogenesis - reactive oxygen species
mcal05211  Renal cell carcinoma
mcal05230  Central carbon metabolism in cancer
mcal05231  Choline metabolism in cancer
mcal05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:mcal00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    110306746 (Hif1a)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110306746 (Hif1a)
   04137 Mitophagy - animal
    110306746 (Hif1a)
   04148 Efferocytosis
    110306746 (Hif1a)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    110306746 (Hif1a)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    110306746 (Hif1a)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110306746 (Hif1a)
   05205 Proteoglycans in cancer
    110306746 (Hif1a)
   05208 Chemical carcinogenesis - reactive oxygen species
    110306746 (Hif1a)
   05230 Central carbon metabolism in cancer
    110306746 (Hif1a)
   05231 Choline metabolism in cancer
    110306746 (Hif1a)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110306746 (Hif1a)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    110306746 (Hif1a)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    110306746 (Hif1a)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mcal03000]
    110306746 (Hif1a)
Transcription factors [BR:mcal03000]
 Eukaryotic type
  Basic helix-loop-helix (bHLH)
   Factors with PAS domain
    110306746 (Hif1a)
SSDB
Motif
Pfam: PAS_3 PAS_11 HIF-1a_CTAD PAS HIF-1 PAS_9 PAS_4 DDRGK HLH
Other DBs
NCBI-GeneID: 110306746
NCBI-ProteinID: XP_021034481
Ensembl: MGP_CAROLIEiJ_G0017848
UniProt: A0A6P5QYP1
Position
12:68519656..68559210
AA seq 830 aa
MEGAGGENEKKNRMSSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASV
MRLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKY
MGLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVRKGKEQNTQRSFFLRMKCTLTSRG
RTMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDS
KTFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQ
VTTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTES
VLKPVESSDMKMTQLFTKVESEDTSCLFDKLKKEPDALTLLAPAAGDTIISLDFGSDGQC
LDTETEDQQLEDVPLYNDVMFPSSNEKLNINLAMSPLPASETPKPLRSSADPALNQEVAL
KLESSPESLGLSFTMPQIQDRPASPSDGSTRQSSPEPNSPSEYCFDVDSDMVNVFKLELV
EKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESNSPSPPSMSTV
TGFQQTQLQKPTITATATTTATTATTDESKTETKDNKEDIKILIASPSSTQVPQETTTTK
ASAYSGTHSRTASPDRAGKRVIEQTDKAHPRSLNLSVTLNQRNTVPEEELNPKTIASQNA
QRKRKMEHDGSLFQAAGIGTLLQQPGDCAPAMSLSWKRVKGFISSEQNGTEQKTIILIPS
DLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq 2493 nt   +upstreamnt  +downstreamnt
atggagggcgccggcggcgagaacgagaagaaaaataggatgagttctgaacgtcgaaaa
gaaaagtctagagatgcagcaagatctcggcgaagcaaagagtctgaagttttttatgag
cttgctcatcagttgccacttccccacaatgtgagctcacatcttgataaagcttctgtt
atgaggctcaccatcagttatttacgtgtgagaaagcttctggatgccggtgatctagac
attgaagatgaaatgaaagcacagatgaactgcttttatctgaaagccctggatggcttt
gtaatggtgctaacagatgacggtgacatgatttacatttctgataacgtgaacaaatac
atggggttaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgt
gaccatgaggaaatgagagaaatgcttacacacagaaatggcccagtgagaaaaggaaaa
gaacaaaacacacagcggagcttttttctcagaatgaagtgcaccctaacaagccggggg
aggacgatgaacatcaagtcagcaacgtggaaggtgcttcactgcacgggccatattcat
gtctatgataccaacagtaaccaacctcagtgtgggtacaagaaaccacccatgacgtgc
ttggtgctgatttgtgaacccattcctcatccgtcaaatattgaaattcctttagacagc
aagacatttctcagtcgacacagcctcgatatgaaattttcttactgtgatgaaagaatt
actgagttgatgggttatgagccggaagaacttttgggccgctcaatttatgaatattat
catgctttggattctgatcatctgaccaaaactcaccatgatatgttcactaaaggacaa
gtcaccacaggacagtacaggatgcttgccaaaagaggcggatacgtctgggttgaaact
caagcaactgtcatatataatacgaagaactcccagccacagtgcattgtgtgtgtgaat
tatgttgtaagtggtattattcagcacgacttgattttctcccttcaacaaacagaatct
gtgctcaaaccagttgaatcttcagatatgaagatgactcagctgttcaccaaggttgaa
tcagaggatacaagctgcctttttgataagcttaagaaggagcctgacgctctcactctg
ctggctccagctgctggcgacaccatcatctctctggattttggcagcgatggtcagtgc
ttagacacagaaactgaagatcaacaacttgaagatgttccattatataatgatgtaatg
tttccttcttctaatgaaaaattaaatataaacctggcaatgtctcctttacctgcgtct
gaaacgccaaagccacttcgaagtagtgctgatcctgcactgaatcaagaggttgcatta
aaattagaatcaagtccagagtcactgggactttcttttaccatgccccagattcaagat
cggccagcaagtccttctgatggaagcactagacaaagttcacctgagcctaacagtccc
agtgaatattgctttgatgtggatagcgatatggtcaatgtattcaagttggaactggtg
gaaaaactgtttgctgaagacacagaggcaaagaatccattttcaactcaggacactgat
ttagacttggagatgctggctccctatatcccaatggatgatgatttccagttacgttcc
tttgatcagttgtcaccattagagagcaattctccaagccctccaagtatgagcacagtt
accgggttccagcagacccagttacagaaacctaccatcactgccactgccaccacaact
gctaccactgccaccaccgatgaatcaaaaacagagacaaaggacaataaagaagatatt
aaaatactgattgcatctccatcttctacccaagtacctcaagaaacgaccactactaag
gcatcagcatacagtggcactcacagtcggacagcctcaccagacagagcaggaaagaga
gtcatagaacagacagacaaagctcatccaaggagccttaacctgtctgtcactttgaat
caaagaaatactgttcctgaggaagaattaaacccaaagacaatagcttcgcagaatgct
cagaggaagcgaaaaatggaacatgatggctccctttttcaagcagcaggaattggaaca
ttactgcagcaaccaggtgactgtgcacctgctatgtcactttcttggaaacgagtaaaa
ggattcatatctagtgaacagaatggaacggagcaaaagacaattattttaataccctcc
gacttagcctgtaggctgctggggcagtcaatggatgagagtggattaccacagctgacc
agttacgactgtgaagttaatgctcctatacaaggcagcagaaacctactgcagggtgaa
gaattactcagagctttggatcaagttaactga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (14)   
   KEGG PATHWAY (14)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (8)   
   UniProt (1)   
   RefSeq(pep) (7)   
DNA sequence (7)   
   RefSeq(nuc) (7)   
Protein domain (9)   
   Pfam (9)   
All databases (45)   

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