KEGG   Mus musculus (mouse): 16801
Entry
16801             CDS       T01002                                 

Symbol
Arhgef1, L, Lbc, Lbcl2, Lsc
Name
(RefSeq) Rho guanine nucleotide exchange factor (GEF) 1
  KO
K12330  Rho guanine nucleotide exchange factor 1
Organism
mmu  Mus musculus (mouse)
Pathway
mmu04270  Vascular smooth muscle contraction
mmu04611  Platelet activation
mmu04810  Regulation of actin cytoskeleton
mmu04928  Parathyroid hormone synthesis, secretion and action
mmu05135  Yersinia infection
mmu05163  Human cytomegalovirus infection
mmu05200  Pathways in cancer
mmu05205  Proteoglycans in cancer
mmu05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16801 (Arhgef1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    16801 (Arhgef1)
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    16801 (Arhgef1)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    16801 (Arhgef1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16801 (Arhgef1)
   05205 Proteoglycans in cancer
    16801 (Arhgef1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    16801 (Arhgef1)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    16801 (Arhgef1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    16801 (Arhgef1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    16801 (Arhgef1)
Membrane trafficking [BR:mmu04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    16801 (Arhgef1)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PH_13 AbiJ_NTD3
Other DBs
NCBI-GeneID: 16801
NCBI-ProteinID: NP_001123624
MGI: 1353510
Ensembl: ENSMUSG00000040940
Vega: OTTMUSG00000029276
UniProt: Q61210
Position
7; 7 A3
AA seq 920 aa
MGEVAGGAAPGPPRSGLVSIIIGAEDEDFENELEANSEDQNSQFQSLEQVKRRPAHLMAL
LQHVALQFEPGPLLCCLHADMLSSLGPKEAKKAFLDFYHSFLEKTAVLRVPVPPSVAFEL
DRTRPDLISEDVQRRFIQEVVQSQQAAVSRQLEDFRSKRLMGMTPWEQELSLLEPWIGKD
RGNYEARERHVAERLLSHLEETQHTISTDEEKSAAVVTAISLYMRHLGVRTKSGDKKSGR
NFFRKKVMGNRRSDEPPKTKKGLSSILDPARWNRGEPSAPDCRHLKVEADAEKPGPADRK
GGLGMSSRDRTVGTPGQDNPGVSLHPLSTDSVDSREPGVDTPQEPGDTPPQGPTSLEPLA
PPESTEDNGETESPEPGDDGEPGRSGLELEPEEPPGWRELVPPDTLLSLPKSQVKRQEVI
SELLVTEAAHVRMLRVLHDLFYQPMADGGFFPLDELQNIFPSLDELIEVHSLFLDRLMKR
RQESGYLIEEIGDVLLARFDGAEGSWFQKISSRFCSRQSFALEQLKAKQRKEPRFCAFVQ
EAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQSIGQNTEESTERGKVELAAECCREILHH
VNQAVRDMEDLLRLKDYQRRLDLTHLRQSSDPMLSEFKNLDITKKKLVHEGPLTWRVTKD
KAIEVHVLLLDDLLLLLQRQDERLLLKSHSRTLTPTPDGKTMLRPVLRLTSAMTREVATD
HKAFYVIFTWDQEAQIYELVAQTSSERKNWCNLITETAGSLKVPAPASRLKPRPSPSSIR
EPLLSSSENGTGGAEMAPADARTERLLNDLLPFCRPGPEGQLAATALQKVLSLKQILLST
EEDSGAGPPRDGDGVPGGRAPGPVHTQEIEENLLSLEVAIRQLEELEEEFCRLRPLLSQL
GGTLSPNLAAPERSAQTGLS
NT seq 2763 nt   +upstreamnt  +downstreamnt
atgggagaagtcgccggaggggcggccccagggcctccccggtctggcctggtgtccatc
atcatcggggcggaggatgaggattttgagaacgagctggaggcgaactcagaagatcaa
aacagccagttccagagcctagagcaagtgaagcgccgccctgcccacctcatggccctc
ctgcagcatgtggccctgcagttcgagccaggaccactgctctgctgcctgcatgcagac
atgctgagctctctgggccccaaagaagccaagaaggccttccttgacttctatcacagt
ttcctggagaagactgcggttctacgggtgccggtccctcccagtgtcgcttttgaactt
gatcgtactcgacctgatctgatctctgaggatgtccagaggcggttcatacaagaggtg
gtgcagagccagcaggcagccgtgagccgtcagctagaggacttccgctccaagcggctc
atgggcatgacgccctgggagcaggaactgagcctgctggagccctggattgggaaagac
cgaggcaactatgaggcccgggagcggcatgttgcggagcggctgctgtcccacctggag
gagacccagcataccatctctacagatgaagagaaaagtgctgctgtggtcactgccatc
agcctgtatatgcgccaccttggagtccggaccaagagtggggacaagaagtcgggaagg
aacttcttccggaaaaaggtgatggggaatcggaggtcagacgaacccccaaagacaaag
aaagggctgagcagtatcctagatcctgcacgttggaaccggggagagccatccgctcca
gattgtcgacatctaaaggtcgaggctgatgcagagaagccaggccctgcagaccggaag
ggaggcctgggtatgtcttctcgggacaggactgttgggactcctggacaggacaaccca
ggagtctccctgcaccctctgtctacagacagcgtcgactcccgggaaccaggcgtggat
accccgcaggagccaggggatacacccccacagggccctaccagcctggagcccctggcg
cccccagagagcacagaggacaatggcgagactgagagccctgagcccggagatgatggg
gagccaggacggtcaggcctggaactggaaccagaagaacctcctgggtggagggaactc
gtgcccccagacaccctgctcagtctgcccaagagccaagtgaagcggcaagaggtcatc
agcgagctgctcgtgactgaggcagctcacgtgcgcatgctacgggtactgcatgacctc
ttctaccagcccatggcggatggaggcttcttccctctggacgagctgcagaacatcttc
ccgagcctggatgagctcatcgaggtgcactccctgttcctcgatcgcttgatgaagcgg
agacaagagagtggctacctcattgaggagatcggcgatgtgctactggcccggttcgat
ggtgctgagggctcatggttccagaagatctcctcccgcttctgcagccgccagtcgttc
gctctagagcagctcaaagccaagcagcgcaaggagcctcggttctgtgcctttgtgcag
gaagctgagagccgcccgagatgccggcgcctacagttaaaggacatgatccccactgag
atgcagcgactgaccaagtacccactgctgctacagagcatcgggcagaacacagaggag
tctacagaacgagggaaagtggagcttgcagctgagtgctgccgggagattctgcaccat
gtcaatcaagccgtccgtgacatggaggacctgctgcggctcaaggattaccagcggcgc
ctggacttgactcacctacggcagagcagtgaccctatgctgagcgagttcaagaacctg
gacatcactaagaagaagttggtccatgaaggccccctcacgtggcgagtgaccaaagac
aaagctatagaagtgcacgtgctcttgctggacgacctgctgctgctgctccagcgccag
gacgagaggctgctgctcaagtcccacagccggacgctgacacctacccccgatggcaag
accatgctgcggccggtgctccggctcacctctgccatgacccgagaggtggccactgat
cacaaagctttctacgtcatttttacctgggaccaggaggcccagatatatgagctggtg
gcacagacatcttcggaacgcaaaaactggtgtaacctcatcactgagactgctggatcc
ctgaaggtccctgcccctgcctcccgcctcaaaccccggcccagcccaagcagcatccga
gaacccctgctcagcagctctgagaatggcactggaggcgcagagatggctccagctgat
gccaggacagagcggctcctcaatgacctcctgcccttctgcagaccaggcccagagggc
cagcttgctgccacagcccttcagaaagtactgtccctgaagcagatcctgctaagcact
gaggaagacagtggagcggggcctccccgcgatggggatggggtgcctggtggtagggcc
cccggcccagtgcacacccaggagattgaggaaaacttgcttagcttagaggtggccatc
agacaactggaggagttggaagaggaattttgtcgcctaagacccctcctgtcccagctt
ggggggactctgtcccccaacctggctgcacctgaacgctctgctcagacaggcctttca
tga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (66)   
   RefSeq(nuc) (14)   
   GenBank (26)   
   EMBL (26)   
Protein domain (5)   
   Pfam (5)   
All databases (117)   

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