KEGG   Mus musculus (mouse): 19223
Entry
19223             CDS       T01002                                 

Gene name
Ptgis, Cyp8, Cyp8a1, P, Pg, Pgis
Definition
(RefSeq) prostaglandin I2 (prostacyclin) synthase
  KO
K01831  prostacyclin synthase [EC:5.3.99.4]
Organism
mmu  Mus musculus (mouse)
Pathway
mmu00590  Arachidonic acid metabolism
mmu01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    19223 (Ptgis)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:mmu00199]
    19223 (Ptgis)
Enzymes [BR:mmu01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.99  Other intramolecular oxidoreductases
    5.3.99.4  prostaglandin-I synthase
     19223 (Ptgis)
Cytochrome P450 [BR:mmu00199]
 Cytochrome P450, animal type
  CYP8 family
   19223 (Ptgis)
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 19223
NCBI-ProteinID: NP_032994
MGI: 1097156
Ensembl: ENSMUSG00000017969
Vega: OTTMUSG00000001169
UniProt: O35074
Position
2; 2 H3
AA seq 501 aa
MSWAALLGLLAVLLLLLLLLSRRRARRPGEPPLDLGSIPWLGHALEFGRDAASFLTRMKE
KHGDIFTVLVGGRYVTVLLDPHSYDTVVWELRTRLDFHPYAIFLMERIFDLQLPNFNPSE
EKARMKPTLMHRDLQALTEAMYTNLRTVLLGDSTEAGSGWQETGLLEFSYNALLSAGYLT
LYGVEASPRTHESQAQDRVHSADVFHTFRQLDLLLPKLARGSLSAGDKDHACSVKNRLWK
LLSPARLASRADRSSWLESYLRHLEEMGVSEEMQARALVLQLWATQGNMGPTAFWLLLFL
LKNPEALAAVRAELKHTVWQAEQPVSQMTTLPQKILDSMPVLDSVLNETLRLTAAPFITR
EVMADLALPMADGREFSLRRGDRLLLFPFLSPQKDPEIYTEPEVFKYNRFLNPDGSEKKD
FYKDGKRLKNYNMPWGAGHNQCLGKSYAINSIKQFVVLLLTHFDLELGSEDTEVPEFDLS
RYGFGLMQPEEDVPIRYRARL
NT seq 1506 nt   +upstreamnt  +downstreamnt
atgtcctgggctgctctgctcggcctcctggccgtgctattgctgttgctgctgctgctg
agccgccggcgcgcgcggagacctggtgagcctccgttggacctgggcagcatcccctgg
ctgggccatgccttggagtttgggagagatgctgccagcttccttaccaggatgaaggaa
aagcacggtgacatatttactgtgctggtggggggcagatacgtcactgttctcctggac
ccacactcttacgacacagtggtgtgggagctgcgtacacggctggacttccatccctat
gccatcttcctcatggagaggatttttgatctgcagcttccaaatttcaaccccagtgag
gagaaggccaggatgaagccgacgctcatgcacagagacctgcaggcgctcacagaagcc
atgtataccaaccttcgcacggtcctgctgggtgactccacagaagcaggcagtggctgg
caggagacaggtctccttgagttctcctacaacgccctgctcagcgccggctacctgacc
ctatatggagtggaggcctcaccacgcacccatgagagtcaggcccaagatcgtgtccac
tcagcggatgttttccataccttccgccagctggatctgctgctccccaaactggctcga
ggctccttgtcagcgggggataaagaccatgcatgcagtgtcaaaaaccgcctgtggaag
ctgctgtccccagccaggctggcctccagggctgaccggagcagctggctggagagttat
ctgagacatcttgaggagatgggggtgtcagaggagatgcaggcccgggctctggtgttg
cagctctgggccacacaggggaatatgggtcccacggccttctggctccttcttttcctc
ctcaagaatccggaagccctcgccgctgtccgtgcagagctgaagcacacggtctggcaa
gcagagcagcctgtttcacagatgaccacactcccacagaagattctagacagcatgcct
gtgctagacagtgtgctcaatgagacactccggctcacggctgcccccttcatcacccgt
gaggtcatggcagacctggccttgcctatggcagacgggagggaattctctcttcgacgt
ggtgaccgccttctcctctttcccttcctgagtccccagaaggacccagaaatctacaca
gagcctgaggtgtttaaatacaaccgattcttgaacccagatggatctgaaaagaaagat
ttttacaaagatgggaaacggctgaagaattacaacatgccatggggcgcagggcacaac
cagtgcctggggaagagttatgccatcaacagcatcaaacaatttgtcgtcctactgctg
actcatttcgacctggagctgggcagcgaggacacagaggttcctgagtttgacctcagc
agatatggcttcggtctgatgcagccagaggaagacgtgcccatccggtaccgtgccagg
ctgtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical substance (2)   
   KEGG COMPOUND (2)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (16)   
   RefSeq(nuc) (2)   
   GenBank (7)   
   EMBL (7)   
Protein domain (1)   
   Pfam (1)   
All databases (43)   

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